Feature Channels: Biotech

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Released: 1-Oct-2022 12:00 PM EDT
Dual states of Bmi1-expressing intestinal stem cells drive epithelial development and tissue regeneration
Preprints

Nicholas R. Smith, Sidharth K. Sengupta, Patrick Conley, Nicole R. Giske, Christopher Klocke, Brett S. Walker, Noelle McPhail, John R. Swain, Yeon Jung Yoo, Ashley N. Anderson, Paige S. Davies, Nasim Sanati, Theresa N. Nguyen, Kristo

Released: 28-Sep-2022 12:00 PM EDT
A filamentous phage triggers antiviral responses in cystic fibrosis basal airway epithelial cells
Preprints

Medeea C Popescu, Naomi L Haddock, Elizabeth B Burgener, Laura S Rojas-Hernandez, Gernot Kaber, Aviv Hargil, Paul Bollyky, Carlos E Milla

Released: 28-Sep-2022 12:00 PM EDT
A Single-Cell Level Comparison of Human Inner Ear Organoids and the Human Cochlea and Vestibular Organs
Preprints

Wouter H. van der Valk, Edward S.A. van Beelen, Matthew R. Steinhart, Carl Nist-Lund, John C.M.J. de Groot, Peter Paul G. van Benthem, Karl R. Koehler, Heiko Locher

Released: 28-Sep-2022 12:00 PM EDT
Cell circuits between leukemic cells and mesenchymal stem cells block lymphopoiesis by activating lymphotoxin-beta receptor signaling
Preprints

Xing Feng, Ruifeng Sun, Moonyoung Lee, Xinyue Chen, Shangqin Guo, Huimin Geng, Marcus Müschen, Jungmin Choi, Joao Pedro Pereira

Released: 28-Sep-2022 12:00 PM EDT
Royal jelly maintains epidermal stem cell properties by repressing senescence
Preprints

Mariko Moriyama, Yuko Miyake, Tomomi Degawa, Nobuaki Okumura, Hiroyuki Moriyama

Newswise: Keeping Current with Landslide Prediction Tools
Released: 28-Sep-2022 8:00 AM EDT
Keeping Current with Landslide Prediction Tools
American Society of Agronomy (ASA), Crop Science Society of America (CSSA), Soil Science Society of America (SSSA)

Landslides threaten many lives. A new study suggests we could predict landslides better with electrical measurements of soil.

Newswise: Puzzle Medical Devices Inc. Wins TCT 2022 Shark Tank Innovation Competition
Released: 27-Sep-2022 1:05 PM EDT
Puzzle Medical Devices Inc. Wins TCT 2022 Shark Tank Innovation Competition
Cardiovascular Research Foundation (CRF)

The Cardiovascular Research Foundation (CRF) is pleased to announce that Puzzle Medical Devices Inc. has won the TCT 2022 Shark Tank Innovation Competition for its novel circulatory support device that is implanted percutaneously in the abdominal aorta. The competition took place during Transcatheter Cardiovascular Therapeutics (TCT), the world’s premier educational meeting specializing in interventional cardiovascular medicine, September 16-19 in Boston. The winner was also presented with the Jon DeHaan Foundation Award for Innovation in Cardiology.

Released: 27-Sep-2022 12:00 PM EDT
Retrospective analysis of patients with severe combined immune deficiency: A 20-year Single center experience
Preprints

Sevim Busra Korkmaz, Selma Erol Aytekin, Huseyin Tokgoz, Sukru Guner, Ismail Reisli, Sevgi Keles

Released: 27-Sep-2022 12:00 PM EDT
Intertwining neuropathogenic impacts of aberrant circadian rhythm and impaired neuroregenerative plasticity in Huntington’s disease: Neurotherapeutic significance of chemogenetics
Preprints

Sowbarnika Ravichandran, Ramalingam Suhasini, Sudiksha Madheswaran Deepa, Divya Bharathi Selvaraj, Jemi Feiona Vergil Andrews, Viruthachalam Thiagarajan, Mahesh Kandasamy

Released: 27-Sep-2022 12:00 PM EDT
Olfactory microvillar tuft cells direct neurogenesis during allergic inflammation
Preprints

Saltanat Ualiyeva, Evan R Lemire, Amelia Boyd, Caitlin Wong, Evelyn C Aviles, Alice Maxfield, Rachel Roditi, Nora Barett, Kathleen M Bucheit, Tanya M Laidlaw, Joshua A Boyce, Lora G Bankova, Adam L Haber

Released: 27-Sep-2022 12:00 PM EDT
Donor cord blood aging accelerates in recipients after transplantation
Preprints

Makoto Onizuka, Tadashi Imanishi, Kaito Harada, Yasuyuki Aoyama, Jun Amaki, Masako Toyosaki, Shinichiro Machida, Eri Kikkawa, Sanetoshi Yamada, Kazuhiko Nakabayashi, Kenichiro Hata, Ken Higashimoto, Hidenobu Soejima, Kiyoshi Ando

Released: 27-Sep-2022 12:00 PM EDT
ESDR336 - Induced pluripotent stem cell-derived macrophages in an inflammatory skin disease model to study granuloma formation
Preprints

Lisa Kleissl, Anna Redl, Teresa Neuwirth, Ruth Dingelmaier-Hovorka, Ram Pandey, Georg Stary

Released: 27-Sep-2022 12:00 PM EDT
Sleep-wake Disturbance following Allogeneic Hematopoietic Stem Cell Transplantation: Trajectory and Correlates
Preprints

Muthu Veeraputhiran, Jennifer Gernat, Naveen Yarlagadda, Milan Bimali, Ellyn E. Matthews

Released: 27-Sep-2022 12:00 PM EDT
Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elements
Preprints

Ardian Ferraj, Peter A Audano, Parithi Balachandran, Anne Czechanski, Jacob I Flores, Alexander A Radecki, Varun Mosur, David S Gordon, Isha A Walawalkar, Evan E Eichler, Laura G Reinholdt, Christine R Beck

Released: 27-Sep-2022 12:00 PM EDT
Antagonistic H3K79me-H3K9ac crosstalk determines elongation at housekeeping genes to promote pluripotency
Preprints

Coral K Wille, Xiaoya Zhang, Spencer Haws, John Denu, Rupa Sridharan

Released: 26-Sep-2022 12:00 PM EDT
Long non-coding RNA SNHG16 promotes human placenta-derived mesenchymal stem cell proliferation capacity through the PI3K/AKT pathway under hypoxia
World Journal of Stem Cells

BACKGROUNDThe effect of hypoxia on mesenchymal stem cells (MSCs) is an emerging topic in MSC biology. Although long non-coding RNAs (lncRNAs) and messenger RNAs (mRNAs) are reported to play a critical role in regulating the biological character

Released: 26-Sep-2022 12:00 PM EDT
Intercellular mitochondrial transfer as a means of revitalizing injured glomerular endothelial cells
World Journal of Stem Cells

BACKGROUNDRecent studies have demonstrated that mesenchymal stem cells (MSCs) can rescue injured target cells via mitochondrial transfer. However, it has not been fully understood how bone marrow-derived MSCs repair glomeruli in diabetic kidney

Released: 26-Sep-2022 12:00 PM EDT
Strategies to improve the effect of mesenchymal stem cell therapy on inflammatory bowel disease
World Journal of Stem Cells

Inflammatory bowel disease (IBD) includes Crohn’s disease and ulcerative colitis and is an idiopathic, chronic inflammatory disease of the colonic mucosa. The occurrence of IBD, causes irreversible damage to the colon and increases the risk o

Released: 26-Sep-2022 12:00 PM EDT
Overexpression of GATA binding protein 4 and myocyte enhancer factor 2C induces differentiation of mesenchymal stem cells into cardiac-like cells
World Journal of Stem Cells

BACKGROUNDHeart diseases are the primary cause of death all over the world. Following myocardial infarction, billions of cells die, resulting in a huge loss of cardiac function. Stem cell-based therapies have appeared as a new area to support h

Released: 26-Sep-2022 12:00 PM EDT
Aging and Obesity Prime the Methylome and Transcriptome of Adipose Stem Cells for Disease and Dysfunction
Preprints

Shaojun Xie, Sulbha Choudhari, Chia-Lung Wu, Karen Abramson, David Corcoran, Simon G Gregory, Jyothi M Thimmapuram, Farshid Guilak, Dianne Little

Released: 26-Sep-2022 12:00 PM EDT
Improving stem cell-derived pancreatic islets using single-cell multiome-inferred regulomes
Preprints

Han Zhu, Gaowei Wang, Kim-Vy Nguyen-Ngoc, Dongsu Kim, Michael Miller, Georgina Goss, Jenna Kovsky, Austin R Harrington, Diane Saunders, Rebecca Melton, Alvin C Powers, Sebastian Preissl, Francesca M Spagnoli, Kyle J Gaulton,

Released: 25-Sep-2022 12:00 PM EDT
Enhancing Sox/Oct cooperativity induces higher-grade developmental reset
Preprints

Caitlin M. MacCarthy, Vikas Malik, Guangming Wu, Taras Velychko, Gal Keshet, Ralf Jauch, Vlad Cojocaru, Hans Scholer, Sergiy Velychko

Released: 24-Sep-2022 12:00 PM EDT
LINC01137 facilitate pancreatic cancer stemness via the miR-7155-5p/KLF12/AKT axis
Preprints

Kexian Li, Zengyu Feng, Kai Qin, Yang Ma, Shiwei Zhao, Peng Chen, Jiewei Lin, Yongsheng Jiang, Lijie Han, Yizhi Cao, Jiaxin Luo, Minmin Shi, Hao Chen, Jiancheng Wang, Lingxi

Released: 23-Sep-2022 2:05 PM EDT
Rutgers Researchers Aim to 'Edit' Proteins in Humans and Attain Insight into Illness
Rutgers University-New Brunswick

Rutgers researchers are seeking to develop the technology to modify or “edit” protein molecules in the body—an advance that could spur major breakthroughs in human health.

   
Released: 23-Sep-2022 12:00 PM EDT
IRF7 impacts on prostate cancer cell survival in response to radiation
Preprints

Adam Pickard, Francesca Amoroso, Kelsey McCulloch, Andrew Erickson, Ashwin Sachdeva, Rebecca Steele, Debayan Mukherjee, Margaret Dellett, Jonathan McComb, Laura McCaffrey, Claire Hart, Michael Brown, Simon S McDade, David Waugh,

Released: 23-Sep-2022 12:00 PM EDT
Efficacy and safety of synbiotics in patients undergoing autologous hematopoietic stem cell transplantation: A prospective, randomized, double-blind, placebo-controlled pilot study
Preprints

Yu Mizutani, Shinichiro Kawamoto, Michiko Takahashi, Hisayo Doi, Kumiko Wakida, Satoko Tabuchi, Masaaki Tanda, Akihiro Soga, Ruri Chijiki, Hidetomo Takakura, Koji Kawaguchi, Ako Higashime, Marika Watanabe, Hiroya Ichikawa,

Released: 23-Sep-2022 12:00 PM EDT
Breast Cancer With Increased Drug Resistance, Invasion Ability, and Cancer Stem Cell Property Through Metabolism Reprogramming
Preprints

Kian-Hwee Chong, Yao-Jen Chang, Wei-Hsin Hsu, Ya-Ting Tu, Yi-Ru Chen, Ming-Cheng Lee, Kuo-Wang Tsai

Released: 23-Sep-2022 12:00 PM EDT
Germ-stem cells and oocyte production in the Honeybee Queen Ovary
Preprints

Georgia Cullen, Joshua B Gilligan, Joseph G Guhlin, Peter K Dearden

Released: 23-Sep-2022 12:00 PM EDT
Requirement for STAT3 and its target, TFCP2L1 in self-renewal of naïve pluripotent stem cells in vivo and in vitro
Preprints

Sophie Louise Kraunsoe, Takuya Azami, Yihan Pei, Graziano Martello, Kenneth Alan Jones, Thorsten Edwin Boroviak, Jennifer Nichols

Released: 22-Sep-2022 12:00 PM EDT
ESDR573 - Marine and Bovine-Derived Collagen Peptides Inhibit Catagen Development and Generate Diverse Effects on Stem Cells and Progeny in Human Scalp Hair Follicles Ex Vivo
Preprints

Karin Pappelbaum, Nicolina Virgilio, Francisco Jiménez, Wolfgang Funk, Janne Prawitt, Bastian van der Steen, Marta Bertolini

Released: 22-Sep-2022 12:00 PM EDT
Three-dimensional nanofibrous sponges with aligned architecture and controlled hierarchy regulating neural stem cell fate for spinal cord regeneration
Preprints

Shilei Ni, Zhiwei Li, Ye Qi, Lei Sun, Zheng Li, Shaojun Chen, Yuqi Zhang, Yuan Ma, Jinming Han, Zide Wang, Yulin Zhang, Huimin Geng, Bin Huang, Jian Wang, Gang Li,

Released: 22-Sep-2022 12:00 PM EDT
The impact of pretransplant use of tyrosine kinase inhibitors on allogeneic stem cell transplantation in patients with chronic myeloid leukemia - A single-institution retrospective study
Preprints

Shinya Fujita, Masatoshi Sakurai, Hidenori Kasahara, Jun Kato, Yuya Koda, Kentaro Yamaguchi, Kohei Shiroshita, Mikio Okayama, Ryohei Abe, Taku Kikuchi, Takayuki Shimizu, Takehiko Mori, Keisuke Kataoka, Shinichiro Okamoto

Released: 22-Sep-2022 12:00 PM EDT
The relationship between PD-L1 and quiescence in melanocyte stem cell aging.
Preprints

Joseph W. Palmer, Kyrene M. Villavicencio, Misgana Idris, Dominique Weddle, Fabian V. Filipp, William J. Pavan, Melissa L. Harris, Nisc Comparative Sequencing Program - Nhgri



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