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7-Apr-2011 1:00 PM EDT
Women’s Voices Remain Steady Throughout the Month
Federation of American Societies for Experimental Biology (FASEB)

New study contradicts prior research suggesting hormonal status affects voice

7-Apr-2011 1:00 PM EDT
Obesity May Shut Down Circadian Clock in the Cardiovascular System
Federation of American Societies for Experimental Biology (FASEB)

Researchers have found that a master clock gene does not fluctuate regularly as it does in non-obese animals. This means that a key gene clock of the cardiovascular system does not work properly when obesity is present. The findings are believed to be the first of their kind.

1-Apr-2011 9:00 AM EDT
Novel Vaccine Therapy Shows Promise for Extending Survival Time in Patients with Deadly Glioblastoma
American Association of Neurological Surgeons (AANS)

Glioblastoma, or malignant glioma, is the most common malignant brain tumor, and also the most deadly, because it is very resistant to treatment. In general, current treatments have not yielded significant increases in survival rates, which is why research into novel therapies is so crucial. A novel brain tumor vaccine clinical trial study conducted at UCLA demonstrates a longer survival time in patients with glioblastoma.

1-Apr-2011 9:00 AM EDT
Fluorescence Endoscopy Shows Potential for Improved Outcome in Patients with Pituitary Tumors
American Association of Neurological Surgeons (AANS)

Tumors of the pituitary gland, often referred to as “the master gland” can cause striking physical, mental and psychological debilitation in patients. Researchers at Brigham and Women’s Hospital in Boston analyzed the value of fluorescence endoscopy in visually differentiating pituitary tumors from surrounding areas and its potential for improved tumor resection.

1-Apr-2011 9:00 AM EDT
Stereotactic Radiosurgery a Viable Treatment Option for Difficult to Access Posterior Fossa Meningiomas
American Association of Neurological Surgeons (AANS)

Meningiomas are the most common benign intracranial tumors, and in individuals ages 35 and older, the most common type of brain tumor diagnosed. Researchers at the University of Virginia, Charlottesville, analyzed factors predictive of outcomes and recurrence in patients with posterior fossa meningiomas treated with stereotactic radiosurgery.

1-Apr-2011 9:00 AM EDT
Large Randomized FDA Trials Compare Two Common Procedures used for Cervical Disc Disease and Associated Radiculopathy
American Association of Neurological Surgeons (AANS)

Thousands of Americans suffer from episodes of acute or persistent neck and arm pain every year as a result of underlying cervical disc disease. Anterior cervical discectomy and fusion (ACDF) has been the mainstay treatment for many years. This is the largest combined analysis of class 1 data to date comparing the efficacy of artificial disc surgery (arthroplasty) to the ACDF procedure.

1-Apr-2011 9:00 AM EDT
Research Analyzes the Risks and Outcomes of Repeat Stereotactic Radiosurgery for Arteriovenous Malformations
American Association of Neurological Surgeons (AANS)

An arteriovenous malformation (AVM) is a tangle of abnormal and poorly formed blood vessels (arteries and veins), with an innate propensity to bleed. Researchers at the University of Pittsburgh School of Medicine assessed the risks and efficacy of repeat stereotactic radiosurgery in patients with AVMs.

7-Apr-2011 1:00 PM EDT
Pharmacogenetics Testing Offers Way to Reduce Deaths from Drug Toxicity
Federation of American Societies for Experimental Biology (FASEB)

Pharmacogenetics (PGx) is the study of an individual’s variation in DNA sequence related to drug response. The goal is to select the right drug at the right dose and avoid adverse drug reactions or ineffective treatment. A study aims to develop a PGx test for forensics. Researchers announce their results.

7-Apr-2011 1:00 PM EDT
Therapeutically Promising New Findings for Combating Hypertension and Cardiovascular Disease
Federation of American Societies for Experimental Biology (FASEB)

Researchers from Wisconsin and Texas identify benefits of certain EET analogs that increase sodium excretion and lower blood pressure

8-Apr-2011 8:00 AM EDT
Johns Hopkins University Associate Professor of Medicine Earns APS’ Henry Pickering Bowditch Award
American Physiological Society (APS)

Dr. Larissa Shimoda will discuss her research when she presents this year's Bowditch Lecture, "Effects of chronic hypoxia on the pulmonary circulation: Role of HIF-1," on Sunday, April 10, 5:45 pm, during the Experimental Biology meeting at the Walter E. Washington Convention Center, Washington, DC.

8-Apr-2011 8:00 AM EDT
Johns Hopkins University Associate Professor of Medicine Earns APS’ Henry Pickering Bowditch Award
American Physiological Society (APS)

The American Physiological Society has recognized the importance of Dr. Shimoda's work by awarding her the Henry Pickering Bowditch Award Lecture. Award is given to select scientists younger than 42 whose accomplishments are original and outstanding. It is the Society’s second-highest award.

8-Apr-2011 10:30 AM EDT
Insights Gained from Growing Cold-Causing Virus on Sinus Tissue
University of Wisconsin–Madison

Using sinus tissue removed during surgery at University of Wisconsin Hospital and Clinics, researchers at the University of Wisconsin-Madison have managed to grow a recently discovered species of human rhinovirus (HRV), the most frequent cause of the common cold, in culture.

8-Apr-2011 1:15 PM EDT
West Antarctic Warming Triggered by Warmer Sea Surface in Tropical Pacific
University of Washington

New research shows that rising sea surface temperatures in the central Pacific Ocean drive atmospheric circulation that has caused some of the largest shifts in Antarctic climate in recent decades.

7-Apr-2011 1:00 PM EDT
Blueberries May Inhibit Development of Fat Cells
Federation of American Societies for Experimental Biology (FASEB)

Study was performed in tissue cultures taken from mice. The polyphenols showed a dose-dependent suppression of adipocyte differentiation.

7-Apr-2011 1:00 PM EDT
Green Tea and Tai Chi Enhance Bone Health and Reduce Inflammation in Postmenopausal Women
Federation of American Societies for Experimental Biology (FASEB)

Study shows consumption of GTP (at a level equivalent to about 4-6 cups of steeped green tea daily) & participation in tai chi independently enhanced markers of bone health by 3 and 6 months, respectively

8-Apr-2011 8:00 AM EDT
University of Louisville Chief of Cardiovascular MedicineEarns APS’ Walter B. Cannon Award
American Physiological Society (APS)

In honor of his illuminating work, the American Physiological Society has selected Dr. Roberto Bolli to present the Walter B. Cannon Memorial Lecture at the Experimental Biology 2011 meeting (EB 2011).

8-Apr-2011 8:00 AM EDT
Roberto Bolli, MD, to Discuss Cardiac Stem Cell Treatment for Heart Failure
American Physiological Society (APS)

Bolli and colleagues are conducting the groundbreaking study, "Cardiac Stem Cell Infusion in Patients with Ischemic cardiOmyopathy (SCIPIO)," to perfect a technique for using a patient's own cardiac stem cells to regenerate dead heart muscle after a heart attack.

7-Apr-2011 9:15 AM EDT
Scientists Develop “Universal” Virus-Free Method to Turn Blood Cells Into “Beating” Heart Cells
Johns Hopkins Medicine

Johns Hopkins scientists have developed a simplified, cheaper, all-purpose method they say can be used by scientists around the globe to more safely turn blood cells into heart cells. The method is virus-free and produces heart cells that beat with nearly 100 percent efficiency, they claim.

5-Apr-2011 11:35 AM EDT
IPF Drug Fails in New Trial
American Thoracic Society (ATS)

A new study has demonstrated no significant benefit of taking the drug bosentan for idiopathic pulmonary fibrosis (IPF).

7-Apr-2011 11:00 AM EDT
Hawaii Governor Declares “Brain Health Awareness Week,” April 9-16
American Academy of Neurology (AAN)

Hawaii Governor Neil Abercrombie has issued a state proclamation declaring the week of April 9-16, 2011, as “Brain Health Awareness Week” in the Aloha state. The proclamation coincides with two large events in Honolulu; the Brain Health Fair Saturday, April 9, and the American Academy of Neurology’s Annual Meeting at the Hawaii Convention Center April 9-16, which is the world’s largest meeting of neurologists with more than 9,000 attendees.

7-Apr-2011 11:00 AM EDT
Students at Two Hawaii High Schools to Learn How Brain Works from Top Neurologists
American Academy of Neurology (AAN)

Workshop Coincides with the American Academy of Neurology Annual Meeting, Largest in World

Released: 7-Apr-2011 1:00 PM EDT
Findings May Help Keep Pancreatic Disease Off the Menu
Federation of American Societies for Experimental Biology (FASEB)

A researcher determined to manipulate the activation of certain enzymes will present new findings about a previously unknown cellular process that the pancreas uses to selectively detect and gobble up activated enzymes before they can digest the organ, avoiding disease progression.

Released: 7-Apr-2011 9:00 AM EDT
News Release Effectiveness Study Shows 93% of Research Gets Covered
Newswise

The first of its kind, an effectiveness study by Newswise has shown that 93% of research news releases and 77% of feature news releases get at least 5 news clips in major media outlets. The study also explored the reach and relevance of web search results duplicating the original news release.

       
7-Apr-2011 1:00 PM EDT
The Role of Metabolism in Disease
Federation of American Societies for Experimental Biology (FASEB)

Experts on metabolism will convene for a thematic program to discuss scientific advances in understanding the links between metabolic function and the onset of disease.

7-Apr-2011 1:00 PM EDT
What’s Coming Next in the Biochemical Battle of the Bulge?
Federation of American Societies for Experimental Biology (FASEB)

The program will showcase the work of scientists from all over the world who have their sights set on reversing the epidemic of obesity by laying bare and manipulating, to mankind’s advantage, its molecular underpinnings. Nine 25-minute talks and numerous other shorter talks about groundbreaking obesity studies.

7-Apr-2011 1:00 PM EDT
Researchers Present New Findings on Cancer and Gene Therapy
Federation of American Societies for Experimental Biology (FASEB)

A thematic program will bring together researchers from across the country to discuss recent developments in DNA replication, recombination and repair and the importance of these activities in cancer and gene therapy.

7-Apr-2011 1:00 PM EDT
Hot Topics in Chemical Biology and Drug Development
Federation of American Societies for Experimental Biology (FASEB)

Two dozen researchers will go public about their ongoing work aimed at improving our understanding of biological systems and contributing to our cache of healing compounds.

6-Apr-2011 2:50 PM EDT
Experts Issue Recommendations for Evaluating and Treating Pituitary Incidentalomas
Endocrine Society

Today, The Endocrine Society released a new Clinical Practice Guideline (CPG) for the evaluation and treatment of pituitary incidentalomas. The CPG is published in the April 2011 issue of the Journal of Clinical Endocrinology & Metabolism (JCEM), a publication of The Endocrine Society.

7-Apr-2011 1:00 PM EDT
Labor of Love: New Research Shows Physically Active Moms-to-Be Give Babies a Head Start on Heart Health
Federation of American Societies for Experimental Biology (FASEB)

It turns out that exercising during pregnancy might be the earliest intervention strategy available to mothers for improving their child’s heart health after birth.

7-Apr-2011 1:00 PM EDT
Researcher Doggedly Pursues New Treatments for Traumatic Brain Injury Patients in Coma
Federation of American Societies for Experimental Biology (FASEB)

Familiar voices, magnetic stimulation being tested in two clinical trials. One study is a double-blind, randomized trial in which family members and loved ones of the patients play very important roles.

1-Apr-2011 11:00 AM EDT
NEJM Piece Urges Us to Watch UK Adopt New Policy for Valuing Drugs
Johns Hopkins Medicine

The United States should pay close attention to how the United Kingdom carries out plans to assess a new drug’s worth using factors that go beyond clinical and cost effectiveness, according to researchers at the Johns Hopkins Berman Institute of Bioethics. In a commentary to appear in the April 7 issue of the New England Journal of Medicine, the bioethicists detail and discuss a new, “value-based pricing” policy proposed by the British government.

   
29-Mar-2011 11:35 AM EDT
Healthy Welders May Be at Increased Risk for Early Brain Damage
American Academy of Neurology (AAN)

New research suggests that workers exposed to welding fumes may be at risk for developing brain damage in an area of the brain also affected in Parkinson’s disease. The study is published in the April 6, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology.

4-Apr-2011 9:00 AM EDT
New Study Solidifies Role of DISC1 in Risk for Schizophrenia and Other Mental Illness
Johns Hopkins Medicine

Johns Hopkins researchers report the discovery of a molecular switch that regulates the behavior of a protein that, when altered, is already known to increase human susceptibility to schizophrenia and mood disorders.

5-Apr-2011 4:00 PM EDT
Biologists Pinpoint a Genetic Change That Helps Tumors Move to Other Parts of the Body
Massachusetts Institute of Technology (MIT)

MIT cancer biologists have identified a genetic change that makes lung tumors more likely to spread to other parts of the body. The findings, to be published in the April 6 online issue of Nature, offers new insight into how lung cancers metastasize and could help identify drug targets to combat metastatic tumors, which account for 90 percent of cancer deaths.

4-Apr-2011 3:00 PM EDT
Human Taste Cells Regenerate in a Dish
Monell Chemical Senses Center

Following years of futile attempts, new research from the Monell Center demonstrates that living human taste cells can be maintained in culture for at least seven months. The findings provide scientists with a valuable tool to learn about the human sense of taste and how it functions in health and disease.

25-Mar-2011 1:00 PM EDT
GOLFIG Increased Progression-free Survival in Colorectal Cancer Patients
American Association for Cancer Research (AACR)

Oncologists can use colorectal cancer patients’ own immune system to boost the effects of chemotherapy and increase progression-free survival, according to Phase III study results presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.

25-Mar-2011 1:00 PM EDT
Physical Health Scores Predict Breast Cancer Outcomes
American Association for Cancer Research (AACR)

Breast cancer survivors with poor physical health scores had an elevated risk of poorer cancer outcomes, including recurrence and death, according to the results of an observational study presented at the AACR 102nd Annual Meeting 2011, held April 2-6.

25-Mar-2011 1:00 PM EDT
Strawberries May Slow Precancerous Growth in Esophagus
American Association for Cancer Research (AACR)

Freeze-dried strawberries may be an alternative to drugs for the prevention of esophageal cancer, according to research presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.

1-Apr-2011 11:20 AM EDT
NYU Cancer Institute Experts Present at the American Association for Cancer Research 102nd Annual Meeting 2011
NYU Langone Health

Experts from The Cancer Institute at NYU Langone Medical Center presented new research findings at the American Association for Cancer Research 102nd Annual Meeting 2011 held April 2-6, 2011 in Orlando, Florida. NYU Cancer Institute researchers discussed various breakthroughs such as a novel test for early-stage asbestos-related pulmonary cancer, a promising treatment strategy for glioblastomas, genome-wide mapping of nickel-related cancer and greater understanding of melanoma and bladder cancer.

4-Apr-2011 10:25 AM EDT
Socioeconomics Playing Reduced Role in Autism Diagnoses
American Sociological Association (ASA)

While there is an increasing equality in terms of the likelihood that children from communities and families across the socioeconomic spectrum will be diagnosed with autism, a new study finds that such factors still influence the chance of an autism diagnosis, though to a much lesser extent than they did at the height of rising prevalence.

31-Mar-2011 2:05 PM EDT
Rejuvenating Electron Microscopy
UC San Diego Health

Modifying a protein from a plant much favored by science, researchers at the University of California, San Diego School of Medicine and colleagues have created a new type of genetic tag visible under an electron microscope, illuminating life in never-before-seen detail.

1-Apr-2011 8:00 AM EDT
Demystifying Meditation – Brain Imaging Illustrates How Meditation Reduces Pain
Atrium Health Wake Forest Baptist

Meditation produces powerful pain-relieving effects in the brain, according to new research published in the April 6 edition of the Journal of Neuroscience.

31-Mar-2011 3:30 PM EDT
Chronic Fatigue Syndrome Study Probes for XMRV in Central Nervous System
Rutgers University

Investigators have attempted to replicate 2009 findings that associated the XMRV retrovirus with Chronic Fatigue Syndrome. However those studies have been performed on blood. The current study focuses instead on cerebrospinal fluid, given the syndrome's impact on nervous system function.

1-Apr-2011 2:25 PM EDT
Longer-Term Follow-up of Users of Estrogen Therapy Finds Some Changes in Risks
JAMA - Journal of the American Medical Association

Among postmenopausal women with prior hysterectomy who had used estrogen therapy for about 6 years and then stopped, longer-term follow-up indicates that the increased risk of stroke seen during the intervention period had dissipated, the decreased risk of hip fracture was not maintained, while the decreased risk of breast cancer persisted, according to a study in the April 6 issue of JAMA.

1-Apr-2011 2:25 PM EDT
Blood Biomarker Associated with Prevalence, Severity of Alzheimer's, but Not Risk of Development
JAMA - Journal of the American Medical Association

Higher levels in blood of the protein clusterin, also known as apolipoprotein J, are significantly associated with the prevalence and severity of Alzheimer's disease, but not with the risk of onset of new disease, according to a study in the April 6 issue of JAMA.

1-Apr-2011 2:25 PM EDT
Risk of Death from Opioid Overdose Related to Higher Prescription Dose
JAMA - Journal of the American Medical Association

In an analysis of opioid prescription patterns and deaths, receiving higher prescribed doses is associated with an increased risk of opioid overdose death, but receiving both as-needed and regularly scheduled doses is not associated with overdose risk, according to a study in the April 6 issue of JAMA.

1-Apr-2011 2:30 PM EDT
HIV-1 Drug Resistance Mutations Associated with Increased Risk of Antiretroviral Treatment Failure
JAMA - Journal of the American Medical Association

An analysis of data from 10 studies indicates that the presence of low frequency (also called "minority") human immunodeficiency virus type 1 (HIV-1) drug resistance mutations, particularly those involving nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance, are significantly associated with an increased risk of first-line antiretroviral treatment failure, according to an article in the April 6 issue of JAMA.

5-Apr-2011 1:30 PM EDT
Caution for Estrogen Therapy After Hysterectomy
Washington University in St. Louis

An editorial in the April 6 issue of the Journal of the American Medical Association cautions against estrogen-only hormone therapy in women who have had a hysterectomy because of longstanding evidence that it raises the risk of breast cancer.

25-Mar-2011 1:00 PM EDT
Soy Isoflavones Not a Risk for Breast Cancer Survivors
American Association for Cancer Research (AACR)

Soy food consumption did not increase the risk of cancer recurrence or death among survivors of breast cancer, according to the results of a study presented at the AACR 102nd Annual Meeting 2011, held April 2-6.



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