Feature Channels: Kidney Disease

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Newswise: Researchers Identify Mechanism to Explain Role of Certain Gene Mutations in Kidney Disease
Released: 3-Apr-2020 10:25 AM EDT
Researchers Identify Mechanism to Explain Role of Certain Gene Mutations in Kidney Disease
University of Maryland Medical Center

Researchers from the Center for Precision Disease Modeling at the University of Maryland School of Medicine (UMSOM) have uncovered a mechanism that appears to explain how certain genetic mutations give rise to a rare genetic kidney disorder called nephrotic syndrome. Using a drosophila (fruit fly) model, they found mutations in genes that code for certain proteins lead to a disruption of the recycling of the cell membrane.

27-Mar-2020 10:55 AM EDT
Housing Insecurity May Increase Risk of Kidney Disease
American Society of Nephrology (ASN)

• In a study of urban-dwelling individuals, housing insecurity was linked with a higher risk of developing albuminuria, a sign of kidney disease.

26-Mar-2020 11:45 AM EDT
Two types of diabetes drugs similarly effective in reducing heart and kidney disease
Endocrine Society

Two newer types of medications commonly used to treat type 2 diabetes are similar in their ability to reduce major heart complications, including heart attack, stroke and death from cardiovascular disease, according to research accepted for presentation at ENDO 2020, the Endocrine Society’s annual meeting, and publication in a special supplemental section of the Journal of the Endocrine Society.

Released: 31-Mar-2020 8:20 AM EDT
American Society of Nephrology Provides Insights on COVID-19 and Kidney Disease
American Society of Nephrology (ASN)

• The American Society of Nephrology has launched several initiatives to provide guidance on COVID-19 as it relates to the care of patients with kidney disease.

Newswise: New therapeutic strategies proposed for some lung and kidney cancers
26-Mar-2020 4:50 PM EDT
New therapeutic strategies proposed for some lung and kidney cancers
University of Texas M. D. Anderson Cancer Center

New therapeutic strategies proposed for some lung and kidney cancers. Study shows cancers with high levels of the SLC7A11 gene may respond to glucose transporter inhibitor treatment.

24-Mar-2020 4:05 PM EDT
Insights From Ambulatory Blood Pressure Monitoring in Patients with Kidney Disease
American Society of Nephrology (ASN)

• Two studies examine potential benefits of blood pressure monitoring outside of doctors’ offices for patients with kidney disease.

19-Mar-2020 9:00 AM EDT
Does Patient’s Distance to Transplant Centers Affect Likelihood of Being Considered for Transplantation?
American Society of Nephrology (ASN)

• In an analysis of information on adults who began treatment for kidney failure at any Georgia, North Carolina, or South Carolina dialysis facility, the distance from a patient’s residence to the nearest transplant center did not appear to affect the likelihood of transplant-related referrals and evaluations.

13-Mar-2020 5:05 PM EDT
Kidney Health Initiative Completes Project Focused on Clinical Trial End Points for Primary Hyperoxaluria
American Society of Nephrology (ASN)

Available evidence supports the use of marked changes in urine oxalate in CKD stages 1-3a and plasma oxalate in CKD stages 3b-5 as surrogate end points for clinical trials in primary hyperoxaluria. Worsening kidney function is considered an acceptable clinical trial end point; however in many patients with primary hyperoxaluria, kidney function is not lost at a rapid rate until very advanced stages of disease. Kidney stones are clinically meaningful, though lack sufficient standards for measurement and monitoring. Their role as a feasible clinical end point should be reconsidered as more data becomes available.

Released: 13-Mar-2020 4:30 PM EDT
Diagnosing Hypertension in Children
American Society of Nephrology (ASN)

• Study results call into question the utility of testing blood pressure load—the proportion of elevated blood pressure readings detected over 24 hours—for diagnosing hypertension in children.

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