In some people, the brain protein tau collects into toxic tangles that damage brain cells and contribute to diseases such as Alzheimer’s. Researchers at Washington University School of Medicine in St. Louis have found a drug that can lower tau levels and prevent some neurological damage.
Polyhedral boranes have become the basis for the creation of cancer therapies, enhanced drug delivery and new contrast agents needed for radioimaging and diagnosis. Now, a researcher at the University of Missouri has discovered an entirely new class of materials based on boranes that might have widespread potential applications, including improved diagnostic tools for cancer and other diseases as well as low-cost solar energy cells.
For many families, normal activities, such as going to a large family gathering or an amusement park, can be difficult to navigate with a child with autism, as the child may be act out due to being overwhelmed by extra noises and stimulation. To help families deal with such situations, specialists at the University of Missouri Thompson Center for Autism and Neurodevelopmental Disorders have been successfully integrating applied behavior analysis (ABA), the science of understanding why people behave in various ways and how understanding those motivations can shape behavior.
Triple-negative breast cancers, which comprise 15 to 20 percent of all breast tumors, are a particularly deadly type of breast disease that often metastasize to distant sites. Now, University of Missouri researchers have found that luteolin, a natural compound found in herbs such as thyme and parsley, and vegetables such as celery and broccoli, could reduce the risk of developing metastasis originating from triple-negative breast cancer in women.
It is of interest, not only because it is a staple crop in Sub-Saharan Africa, but because grain sorghum yields have been flat or declining due to the lack of sufficient investment in the development of new improved varieties. Sorghum is very resilient to drought and heat stress. Natural genetic diversity in sorghum makes it a promising system for identifying stress-resistance mechanisms in grasses that may have been lost during the domestication of related cereal crops. It is among the most efficient crops in conversion of solar energy and use of water, making it an ideal crop to target for improvement to meet the predicted doubling of global food demand by 2050.
The Vasculitis Foundation will hold its 2017 Baltimore Regional Conference on Saturday, February 4, in Bethesda, Maryland.
A new technique helps biologists tinker with genes, whether the goal is to turn cells into tiny factories churning out medicines or to study their effects on human health. The technique allows scientists to precisely regulate how much protein is produced from a particular gene.
Should a bystander intervene if he or she sees an adult screaming at or hitting a child? Saint Louis University is studying how and when to take action.
Fixing flaws introduced during the machining of large components used in the aircraft and heavy equipment industries can be time-consuming for manufacturers – and costly if they must scrap the flawed parts after they’ve been fabricated. A new approach developed by researchers at Missouri University of Science and Technology is helping manufacturers eliminate those flaws before the parts are created.
Advance directives, or living wills, are the legal documents individuals use to communicate their treatment preferences when faced with serious injuries or illnesses. Following a new study, Colleen Galambos, professor in the University of Missouri School of Social Work, says that more attention to how advance directives are used in nursing homes may reduce unnecessary care and save health care costs, all while respecting residents’ wishes.
Microbes can persist in people for years after an illness, even in people who are healthy and immune to recurrence. Now, researchers have found a clue to this seeming paradox: Persistent microbes are constantly multiplying and being killed, keeping the immune system prepared for any new encounters.
If you are on Obamacare, you are likely a better tenant or homeowner.
Amid Trump comments and stock dive, let WUSTL expert on the history of the pharmaceutical industry Michael Kinch walk you through pharma "Valley of Death."
This report details the VF's accomplishments since its Second International Vasculitis Research Consensus Conference held in Chicago, Illinois in 2012. During the conference, participants evaluated programs and explored new areas of inquiry that the Foundation could fund over the next five years.
Despite announcing in his first press conference that he would deal with a pharmaceutical industry “getting away with murder,” President-elect Donald Trump doesn’t seem to have a clear path for how he will reduce drug prices, said Rachel Sachs, associate professor of law at Washington University in St.
Decades of psychological research cast doubt Research on eyewitness testimony has shown that false details put forth during an interrogation can lead some people to develop vivid memories of events that never happened. While this “false memory” phenomenon is alive and well, new research suggests that a bit of misinformation also has potential to improve our memories of past events — at least under certain circumstances.
The work habits of ants could provide valuable insight into making our societies more productive and sustainable, says a team of Missouri S&T researchers.
Warfarin is a commonly prescribed blood thinner used to prevent harmful blood clots. However, the drug requires frequent monitoring, daily dosing and can result in serious negative effects when mixed with vitamin K, a vitamin commonly found in vegetables such as lettuce or broccoli. Now, a new study from University of Missouri Health Care has found that using electronic health records (EHR) can improve the care patients receive after they leave the hospital and eliminate potential confusion among care providers and pharmacists.
A team of seismologists analyzing the data from 671 earthquakes that occurred between 30 and 280 miles beneath the Earth's surface in the Pacific Plate as it descended into the Tonga Trench were surprised to find a zone of intense earthquake activity in the downgoing slab. The pattern of the activity along the slab provided strong evidence that the earthquakes are sparked by the release of water at depth.
SLU professor of physical therapy Ethel Frese, DPT, shares many ways daily exercise contributes to good health and quality of life.
Studies provide fresh insight into how such tiny wild flowers continue to thrive and reproduce.
One in 68 American children lives with autism spectrum disorder, according to the Centers for Disease Control and Prevention. Many of these children also have significant gastrointestinal issues, but the cause of these symptoms is unknown. Now, researchers from the University of Missouri School of Medicine suggest that the gastrointestinal issues in these individuals with autism may be related to an increased reaction to stress. It’s a finding the researchers hope could lead to better treatment options for these patients.
Engineers at Washington University in St. Louis develop new nanoparticle technology that eliminates the need for cold storage in some medical diagnostic tests.
Electronic components that can be elongated or twisted – known as “stretchable” electronics – could soon be used to power electronic gadgets, the onboard systems of vehicles, medical devices and other products.
Researchers at Washington University School of Medicine in St. Louis have found that although many smokers with serious mental illnesses would like to quit smoking, many psychiatrists and caseworkers aren't aware of their patients' wishes and, consequently, haven't prescribed medications or referred them to services to help them stop smoking.
A song is just a song, but as time goes by, something as random as a song’s length could be the difference in whether you miss an important deadline or arrive late for an appointment, suggests time-management research from Washington University in St. Louis.
Welders exposed to airborne manganese at estimated levels well under federal safety standards develop neurological problems, according to a study at Washington University School of Medicine in St. Louis. Current safety standards may not adequately protect welders from the dangers of the job.
New research from Washington University in St. Louis’s Olin Business School shows price hikes in ride-sharing services such as Uber and Lyft during peak use times, such as New Year’s Eve, can actually benefit both drivers and consumers.
A Saint Louis University geriatrician says her patients frequently feel better when she reduces the number of medicines they take. She advocates older adults who take five or more medications talk their doctors annually about triaging their pill boxes.
The first academic study to estimate the cumulative lifetime risk of a child maltreatment investigation, completed by researchers at the Brown School at Washington University in St. Louis, reveals that 37 percent of U.S. children prior to their 18th birthday are the subject of an investigated child neglect and abuse report — and 53 percent of black children.
Do big-brained creatures steal energy for them from other organs or eat more to supply this expensive tissue? New work in large-brained fish suggests skimping elsewhere is not enough to meet the energy demands of an extreme brain.
After World War II, French Holocaust survivors returned to their homes to find them stripped of personal belongings and occupied by new inhabitants. Attempts to reclaim those belongings were key in efforts to rebuild Jewish political and social inclusion after the war, says historian Shannon Fogg.
Scientists at Washington University School of Medicine in St. Louis have detailed the structure of a molecule that has been implicated in Alzheimer’s disease. Knowing the shape of the molecule — and how that shape may be disrupted by certain genetic mutations — can help in understanding how Alzheimer’s and other neurodegenerative diseases develop and how to prevent and treat them.
A team led by an engineer at Washington University in St. Louis found a novel approach to neutralize a cancer-causing chemical in drinking water.
According to the latest data from the Centers for Disease Control and Prevention, one in 45 children is diagnosed with autism. As these children age, experiences such as leaving school, finding jobs and living alone can be stressful for adolescents with autism as well as their caregivers. Researchers from the University of Missouri have conducted the first study analyzing the perspectives of adolescents with autism to identify challenges as they “age out” of services. The researchers say these findings highlight the need for social workers and providers to assist children with autism as they transition to adulthood.
An international team led by Washington University School of Medicine in St. Louis has selected a third investigational drug to be tested in a worldwide clinical trial – already underway – aimed at finding treatments to prevent Alzheimer’s disease.
A Washington University physicist practiced at finding tiny diamonds in stardust from the pre-solar universe has repeatedly failed to find them in Younger Dryas sedimentary layers, effectively discrediting the hypothesis that an exploding comet caused the sudden climate reversal at the end of the last Ice Age.
A team of researchers from Missouri University of Science and Technology and National and Kapodistrian University of Athens in Greece have demonstrated a more efficient, less cost-prohibitive way to split water into its elements of hydrogen and oxygen. Their approach could make hydrogen fuel a more viable energy source in the future while addressing the technological challenge of developing clean and renewable energy without depleting earth’s natural preserves.
The complex process regulating gene expression is often compared to following a recipe. Miss a genetic ingredient, or add it in the wrong order, and you could have a disaster on your hands.
Saint Louis University scientist Angel Baldan, Ph.D., reports that turning off a protein found in liver and adipose tissue significantly improves blood sugar levels and reduces body fat in an animal model.
Adults and teenagers with depression don't respond to rewards in a normal manner. Although depression has been diagnosed in children as young as 3, it hasn't been clear whether their responses to rewards also may be blunted. So Washington University researchers studied kids ages 4 to 7 and found that, like adults, when the children were depressed, their brains were less likely to respond to rewards. The researchers say insensitivity to rewards may serve as a "red flag" for depression in young children.
Scientists under VIRCA Plus are developing improved cassava varieties to enhance the livelihoods and health status of African farm families.
Girls with a rare genetic disorder caused by mutations in the Nf1 gene are much more likely to lose their vision than boys with the same mutations. Researchers at Washington University School of Medicine in St. Louis believe estrogen activates immune cells that damage the nerves necessary for sight.
Physical inactivity is a global health problem that leads to approximately 3.2 million deaths each year, according to the World Health Organization. Researchers from the University of Missouri School of Medicine have found that a government-sponsored community activity program in Brazil is improving activity levels of women. The researchers believe the program could be scaled up and adapted to other communities around the world.
Dr. Delbert E. Day, a prolific inventor whose work with specialty glasses has led to treatments for cancer, bone tissue regeneration and wound care, has been named a National Academy of Inventors Fellow.
A Saint Louis University germ expert suggests strategies to cut your risk of getting sick if you travel during the holidays.
The newly passed 21st Century Cures Act awaiting President Obama’s signature will provide necessary funding to help those with mental illnesses, but a mental health expert at Washington University in St. Louis says it should focus more on mental health outcomes of those suffering right now.“Over 40 million Americans suffer from a mental health condition at any given time,” said Ryan Lindsay, associate professor of practice and chair of the mental health concentration at the Brown School.
Greater stress and anxiety resulting from economic insecurity may be at least partly to blame for the U.S. death rate that the government announced Dec. 8 has increased for the first time in a decade, says an expert on poverty and inequality at Washington University in St. Louis.“For the first time since 1993, the overall life-expectancy rate in the United States last year actually went down, according to the Centers for Disease Control and Prevention,” said Mark Rank, the Herbert S.
Researchers at the University of Missouri School of Medicine examined the effectiveness of peer support interventions and found that the interventions were effective at improving the blood sugar levels of participants from minority groups, especially those of Hispanic ethnicity.
Your commute to work may be smoother in the future, thanks to new federally funded research at Missouri University of Science and Technology.
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