This research shows that both Pseudomonas and Burkholderia use toxic weaponry, called Type VI Secretion Systems (T6SS), to compete with and establish dominance over each other. It could be possible to target or mimic this weaponry to defeat the bacteria before they cause irreparable lung damage.
Patients with underlying conditions such as asthma or other lung problems should be checked on regularly by pulmonologists or primary-care doctors for at least six months. Some will need to be monitored for one to three years, according to a new opinion piece posted online today in The Lancet-Respiratory Medicine.
Aug. 3, 2020─ More than 30 years after the last guidance on the clinical evaluation of hypersensitivity pneumonitis (HP), the American Thoracic Society – in collaboration with the Asociación Latinoamericana de Tórax or ALAT and the Japanese Respiratory Society– has developed new guidelines for clinicians. The guidelines are available online ahead of print in the American Journal of Respiratory and Critical Care Medicine.
Join us on Aug. 5-10 2020 for ATS 2020 Virtual, when the American Thoracic Society will host a mix of live and pre-recorded sessions in pulmonary, critical care, and sleep medicine. Press are invited to attend (see press guidelines) and may register now. Same day registration will be available during the meeting.
Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified the process by which stem cells in the airways of the lungs switch between two distinct phases — creating more of themselves and producing mature airway cells — to regenerate lung tissue after an injury.
To provide another layer of support for lung transplant recipients, the Keck Medicine of USC lung transplant team launched a two-year observational pilot study to monitor patients post-discharge using Bluetooth-enabled devices and computer tablets.
According to an open-access article published in ARRS' American Journal of Roentgenology (AJR), lung ultrasound (US) was highly sensitive for detecting abnormalities in patients with coronavirus disease (COVID-19), with B-lines, a thickened pleural line, and pulmonary consolidation the most commonly observed features.
For its lifesaving care of patients with severely injured hearts and lungs, University of Virginia Medical Center has earned the Extracorporeal Life Support Organization’s Platinum Level Center of Excellence Award, the international group’s highest honor. Fewer than 30 hospitals worldwide have earned this award.
Smoking cessation initiatives notwithstanding, along with provocative public health campaigns and clinical guidance, quitting tobacco has remained elusive for many smokers. The American Thoracic Society’s new clinical practice guideline on treatment for tobacco dependence in adults addresses how clinicians may deal with patients’ reluctance to quit, one of a number of issues not previously assessed in the older guidelines.
Physicians are studying whether vadadustat, an investigational therapy, could protect the lungs of COVID-19 patients by triggering the body’s protective response to low oxygen levels in a randomized Phase II clinical trial at UTHealth.
Keck Medicine of USC physicians are enrolling patients as part of an international clinical trial to evaluate the safety and efficacy of an antiviral drug, DAS181, as a possible treatment for hospitalized patients with severe COVID-19.
As the number of young adults infected with the coronavirus surges throughout the nation, a new study by researchers at UCSF Benioff Children's Hospitals indicates that youth may not shield people from serious disease.
A multidisciplinary team from Columbia Engineering and Vanderbilt University has now demonstrated that severely injured donor lungs that have been declined for transplant can be recovered outside the body by a system that uses cross-circulation of whole blood between the donor lung and an animal host. For the first time, a severely injured human lung that failed to recover using the standard clinical EVLP was successfully recovered during 24 hours on the team’s cross-circulation platform.
University Hospitals Cleveland Medical Center physicians completed evaluation for the GE Healthcare Critical Care Suite, and the technology is now in daily clinical practice – flagging between seven to 15 collapsed lungs per day within the hospital. No one on the team could have predicted the onset of the COVID-19 pandemic, but this technology and future research with GEHC may enhance the capability to improve care for COVID-19 patients in the ICU. Critical Care Suite is now assisting in COVID and non-COVID patient care as the AMX 240 travels to intensive care units within the hospital.
We see and hear new COVID-19 news almost every minute of the day. But separating facts from fiction can get challenging, especially when it comes to masks. We bust some common mask myths with two Penn State Health experts.
A new study at Intermountain Primary Children’s Hospital in Salt Lake City has found that follow-up appointments for hospitalized children treated for childhood bronchitis are often not necessary, and that switching from mandatory to “as-needed” follow-up care can save families from unnecessary medical care and expense – and may help guide treatment during the COVID-19 pandemic.
A new research study provides possible explanations for COVID-19 patients who present with extremely low, otherwise life-threatening levels of oxygen, but no signs of dyspnea (difficulty breathing). This new understanding of the condition, known as silent hypoxemia or “happy hypoxia,” could prevent unnecessary intubation and ventilation in patients during the current and expected second wave of coronavirus.
Some of America’s favorite Independence Day fireworks emit lead, copper, and other toxins, a new study suggests. These metals, which are used to give fireworks their vibrant color, also damage human cells and animal lungs.
More research must be done to investigate the role of air pollution on the epigenome in patients with interstitial lung diseases (ILDs), in order to develop strategies that minimize the effects of these pollutants, according to a new article published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
Jianjun Sun, Ph.D., associate professor in UTEP’s Department of Biological Sciences, led the research on Mycobacterium tuberculosis (Mtb). Sun’s lab has been investigating the mechanisms of Mtb pathogenesis for more than 10 years at UTEP with a specific focus on EsxA, which is a virulence factor essential for Mtb virulence and a preferred target for developing novel anti-TB drugs and vaccines.
Using an in-home portable air cleaner (PAC) can significantly reduce exposure to fine-particle air pollutants – a major risk factor for cardiovascular events in people with pre-existing heart disease, reports a pilot study in the July issue of Journal of Cardiopulmonary Rehabilitation and Prevention. The journal is published in the Lippincott portfolio by Wolters Kluwer.
SHAREInternational collaboration provides important piece of COVID-19 puzzleLA JOLLA—A new study from researchers at La Jolla Institute for Immunology (LJI) and Erasmus University Medical Center (Erasmus MC) shows that even the sickest COVID-19 patients produce T cells that help fight the virus. The study offers further evidence that a COVID-19 vaccine will need to elicit T cells to work alongside antibodies.
An overactive defense response may lead to increased blood clotting, disease severity, and death from COVID-19. A phenomenon called NETosis—in which infection-fighting cells emit a web-like substance to trap invading viruses—is part of an immune response that becomes increasingly hyperactive in people on ventilators and people who die from the disease.
This month the American Thoracic Society (ATS) and the American College of Chest Physicians (CHEST) launched For My Lung Health, a patient-education website and media campaign. Using public service announcements and an education-based website, For My Lung Health focuses on empowering people from underserved communities who live with chronic lung disease.
For many patients admitted to the hospital with COVID-19, surviving the virus is only half of the battle. Once deemed virus-free and ready to be sent home, the often-long road to recovery – including rebuilding lung capacity and overall respiratory health – begins. Two Cedars-Sinai respiratory therapists explain what roadblocks these hospital-admitted patients face when it comes to lung health and offer tips for non-patients looking to improve their overall respiratory health.
A new perspective piece suggests differences in lung physiology and immune function as possible reasons why children are often spared from severe illness associated with SARS-CoV-2, the novel coronavirus that causes COVID-19.
Exposure to wildfire smoke affects the body's respiratory and cardiovascular systems almost immediately, according to new research from the University of British Columbia's School of Population and Public Health.
ATS 2020 Virtual is taking place on Aug. 5-10, but you can register for “Breaking News: Clinical Trial Results in Pulmonary Medicine,” a preview session taking place on June 24 at 2-3:45 pm ET. Review program details here. Please note that all content for the Clinical Trial Results session is embargoed until 2 p.m. ET June 24.
In a new article, scientists provide an exhaustive, evidence-based review of how COVID-19 droplets from infected patients spread through the air and describe how health care professionals can protect themselves. This Pulmonary Perspective is published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine.
An open-access American Journal of Roentgenology (AJR) article exploring the diagnostic value of chest CT for coronavirus disease (COVID-19) pneumonia--especially for patients with negative initial results of reverse transcription-polymerase chain reaction (RT-PCR) testing--found that the less pulmonary consolidation on chest CT, the greater the possibility of negative initial RT-PCR results.
Researchers from UCLA, Harvard Medical School and the University of Tokyo found that during a recent six-year period, homeless people in New York state were more likely to hospitalized and treated with mechanical ventilators for respiratory infections than people who are not homeless. These findings have implications for the COVID-19 pandemic.
In groundbreaking new research, mechanical engineers and computer scientists at the University of Minnesota have developed a 3D printing technique that uses motion capture technology, similar to that used in Hollywood movies, to print electronic sensors directly on organs that are expanding and contracting. The new 3D printing technique could have future applications in diagnosing and monitoring the lungs of patients with COVID-19.