Greater purpose in life may help stave off the harmful effects of plaques and tangles associated with Alzheimer’s disease, according to a new study by researchers at Rush University Medical Center.
A study on a handful of people with suspected mild Alzheimer’s disease (AD) suggests that a device that sends continuous electrical impulses to specific “memory” regions of the brain appears to increase neuronal activity. Results of the study using deep brain stimulation, a therapy already used in some patients with Parkinson’s disease and depression, may offer hope for at least some with AD, an intractable disease with no cure.
Current research does not support the use of smell tests for predicting Alzheimer’s dementia, according to a comprehensive review.
A new study suggests that eating foods that contain omega-3 fatty acids, such as fish, chicken, salad dressing and nuts, may be associated with lower blood levels of a protein related to Alzheimer’s disease and memory problems. The research is published in the May 2, 2012, online issue of Neurology®, the medical journal of the American Academy of Neurology.
A highly toxic beta-amyloid – a protein that exists in the brains of Alzheimer's disease victims – has been found to greatly increase the toxicity of other more common and less toxic beta-amyloids, serving as a possible "trigger" for the advent and development of Alzheimer's, researchers at the University of Virginia and German biotech company Probiodrug have discovered.
Scientists now have a better understanding of how precise memories are formed thanks to research led by Prof. Jean-Claude Lacaille of the University of Montreal’s Department of Physiology. “In terms of human applications, these findings could help us to better understand memory impairments in neurodegenerative disorders like Alzheimer's disease,” Lacaille said. The study looks at the cells in our brains, or neurons, and how they work together as a group to form memories.
Mount Sinai School of Medicine researchers have succeeded in developing a biosynthetic polyphenol that improves cognitive function in mice with Alzheimer’s disease (AD). The findings, published in a recent issue of the Journal of Neuroscience, provide insight in determining the feasibility of biosynthetic polyphenols as a possible therapy for AD in humans, a progressive neurodegenerative disease for which there is currently no cure.
Researchers at Mount Sinai School of Medicine have gained insight into the mechanism by which a pathological brain protein called tau contributes to the progression of Alzheimer’s disease (AD) and other neurodegenerative disorders. This finding, published in the most recent issue of the Journal of Biological Chemistry, may provide the basis for future investigations on how to prevent tau from damaging brain circuits involved in cognitive function.
You think your computer has a lot of memory … if you keep using your computer you may, too. Combining mentally stimulating activities, such as using a computer, with moderate exercise decreases your odds of having memory loss more than computer use or exercise alone, a Mayo Clinic study shows. Previous studies have shown that exercising your body and your mind will help your memory but the new study, published in the May 2012 issue of Mayo Clinic Proceedings, reports a synergistic interaction between computer activities and moderate exercise in “protecting” the brain function in people better than 70 years old.
According to a new study, the neuron-killing pathology of Alzheimer’s disease (AD), which begins before clinical symptoms appear, requires the presence of both amyloid-beta (a-beta) plaque deposits and elevated levels of an altered protein called p-tau.
Study supports application of slow release of immunoglobulins to delay the onset of AD
Researchers at Washington University School of Medicine in St. Louis have shown that brain plaques in mice are associated with disruption of the ability of brain regions to network with each other.
Daily physical activity may reduce the risk of Alzheimer’s disease and cognitive decline, even in people over the age of 80, according to a new study by neurological researchers from Rush University Medical Center.
Daily physical exercise may reduce the risk of Alzheimer’s disease, even in people over the age of 80, according to a study published in the April 18, 2012, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Daily physical activity may reduce the risk of Alzheimer’s disease and cognitive decline, even in people over the age of 80, according to a new study by neurological researchers from Rush University Medical Center.
Boise State University biologist Dr. Troy Rohn describes current Alzheimer's research.
Injection of a small amount of clumped protein triggers a cascade of events leading to a Parkinson’s-like disease in mice, according to an article in the Journal of Experimental Medicine.
Use of a new drug to detect the beta-amyloid plaques in the brain that are hallmark signs of Alzheimer’s disease may help doctors diagnose the disease earlier, according to research that will be presented as part of the Emerging Science program (formerly known as Late-Breaking Science) at the American Academy of Neurology’s 64th Annual Meeting in New Orleans April 21 to April 28, 2012.
A global team has mapped the human genes that boost or sabotage the brain’s resistance to a variety of mental illnesses and Alzheimer’s disease. The UCLA-launched study also uncovered new genes that explain individual differences in brain size and intelligence
A new technique for analyzing brain images offers the possibility of using magnetic resonance imaging (MRI) to predict the rate of progression and physical path of many degenerative brain diseases, report scientists at the San Francisco VA Medical Center and the University of California, San Francisco.
Researchers at the University of California, San Diego and Veterans Affairs San Diego Healthcare System have shown that elevated pulse pressure may increase the risk of cerebrovascular disease (CVD) in older adults with Alzheimer’s disease (AD).
New research finds that a person’s memory declines at a faster rate in the two- and-a-half years before death than at any other time after memory problems first begin. A second study shows that keeping mentally fit through board games or reading may be the best way to preserve memory during late life. Both studies are published in the April 4, 2012, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Perhaps no other biochemist in the world has his own baseball card, but Elih Velázquez-Delgado, who gave up pro ball for science, does. The doctoral student is about to publish his first academic paper on caspase-6, an enzyme that’s causally involved in Alzheimer’s and Huntington’s diseases.
Repeated stress triggers the production and accumulation of insoluble tau protein aggregates inside the brain cells of mice, say researchers at the University of California, San Diego School of Medicine in a new study published in the March 26 Online Early Edition of the Proceedings of the National Academy of Sciences.
Alzheimer’s disease (AD) steals memory and ruins lives. Despite near-daily reports of promising new therapies, AD remains unchecked. Now a new study reveals the mechanism by which AD may cause memory loss, suggesting new therapies.
A new study published in the March 21 issue of Neurology suggests that older adults who are hospitalized may have an increased risk of subsequent cognitive decline. The study, conducted by researchers at the Rush Alzheimer’s Disease Center and the Rush Institute for Healthy Aging, Rush University Medical Center, found that hospitalization of older adults was associated with increased memory and thinking problems.
A new study suggests that older people may have an increased risk of problems with memory and thinking abilities after being in the hospital, according to research published in the March 21, 2012, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Researchers at Weill Cornell Medical College have developed a computer program that has tracked the manner in which different forms of dementia spread within a human brain. They say their mathematic model can be used to predict where and approximately when an individual patient's brain will suffer from the spread, neuron to neuron, of "prion-like" toxic proteins -- a process they say underlies all forms of dementia.
Alzheimer’s disease and other forms of dementia may spread within nerve networks in the brain by moving directly between connected neurons, instead of in other ways proposed by scientists, such as by propagating in all directions, according to researchers who report the finding in the March 22 edition of the journal Neuron.
Women 65 or older who have even mild retinopathy, a disease of blood vessels in the retina, are more likely to have cognitive decline and related vascular changes in the brain, according to a multi-institutional study led by scientists at the University of California, San Francisco (UCSF).
A study published this week in the Journal of Neuroscience shows that the compound epothilone D (EpoD) is effective in preventing further neurological damage and improving cognitive performance in a mouse model of Alzheimer's disease (AD). The results establish how the drug might be used in early-stage AD patients.
UCLA is launching a new UCLA Alzheimer's and Dementia Care program, which will provide comprehensive, coordinated care, as well as resources and support, to patients and their caregivers.
Researchers at the University of California, San Diego, the Medical University of South Carolina, the University of Cincinnati, and American Life Science Pharmaceuticals of San Diego have validated the protease cathepsin B (CatB) as a target for improving memory deficits and reducing the pathology of Alzheimer’s disease (AD) in an animal model representative of most AD patients.
A team of academic researchers has identified the intracellular mechanisms regulated by vitamin D3 that may help the body clear the brain of amyloid beta, the main component of plaques associated with Alzheimer's disease. The early findings show that vitamin D3 may activate key genes and cellular signaling networks to help stimulate the immune system to clear the amyloid-beta protein.
A new marker of Alzheimer’s disease can predict how rapidly a patient’s memory and other mental abilities will decline after the disorder is diagnosed, researchers at Washington University School of Medicine in St. Louis have found.
A scientific method paper and video by Loyola researchers has gone viral. The video, which demonstrates a laboratory technique used to study Alzheimer's disease and many other disorders, has been accessed by more than 14,000 scientists worldwide.
As scientists struggle to find an effective way to prevent Alzheimer's disease, researchers at the University of Wisconsin School of Medicine and Public health may have found a new approach to interrupting the process that leads to the devastating disease.
Mitochondria -- subunits inside cells that produce energy -- have long been thought to play a role in Alzheimer’s disease.
New compounds that visualize Alzheimer's-related plaques on brain scans of living people may soon be available to doctors. Clinician researchers are grappling with whether to scan healthy people, how to reliably read scans, and how to reveal plaque status. A nine-part series by the Alzforum reports the field’s latest progress in tackling these issues.
A promising novel target for potentially treating Alzheimer's disease has been identified in mice. Researchers will present their findings at the Biophysical Society's 56th Annual Meeting in San Diego, Calif.
Researchers have developed an algorithm to predict how and when proteins misfold, with potential implications for neurodegenerative diseases such as ALS and Alzheimer’s. The team will present its findings at the 56th Annual Meeting of the Biophysical Society in San Diego, Calif.
U-M Memory Connection is answered by expert care team, connects patients to physicians, social workers, support groups and more.
For some older adults, the online video game World of Warcraft (WoW) may provide more than an opportunity for escapist adventure. Researchers from North Carolina State University have found that playing WoW boosted cognitive functioning for older adults – particularly those who had scored poorly on cognitive ability tests before playing the game.
Simple tests such as walking speed and hand grip strength may help doctors determine how likely it is a middle-aged person will develop dementia or stroke. That’s according to new research that was released today and will be presented at the American Academy of Neurology’s 64th Annual Meeting in New Orleans April 21 to April 28, 2012.
Researchers at Rush University Medical Center are conducting an early phase clinical trial of a novel drug therapy for patients with dementia due to Alzheimer’s disease. The drug is a new compound called MSDC-0160, which is an insulin sensitizer that modulates mitochondrial metabolism.
The amount and quality of sleep you get at night may affect your memory later in life, according to research that was released today and will be presented at the American Academy of Neurology’s 64th Annual Meeting in New Orleans April 21 to April 28, 2012.
A larger waistline may be linked to an increased risk of decreased mental functioning in people infected with the AIDS virus HIV, according to research published in the February 14, 2012, print issue of Neurology®, the medical journal of the American Academy of Neurology.
UCLA scientists used a brain imaging tool that effectively tracked and predicted cognitive decline over a two-year period. The team had previously developed this tool that can assess the neurological changes associated with mild cognitive impairment and dementia.
New research suggests that consuming between 2,100 and 6,000 calories per day may double the risk of memory loss, or mild cognitive impairment (MCI), among people age 70 and older. The study was released today and will be presented at the American Academy of Neurology’s 64th Annual Meeting in New Orleans April 21 to April 28, 2012. MCI is the stage between normal memory loss that comes with aging and early Alzheimer’s disease.
Ever gone to the movies and forgotten where you parked the car? New UCLA research may one day help you improve your memory. UCLA neuroscientists have demonstrated that they can strengthen memory in human patients by stimulating a critical junction in the brain. Published in the Feb. 9 edition of the New England Journal of Medicine, the finding could lead to a new method for boosting memory in patients with early Alzheimer’s disease.
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