Focus: Hidden - Texas

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T cell discoveries led to game-changing treatment revolutionizing cancer care

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Two UT Southwestern faculty members have been awarded prestigious National Institutes of Health (NIH) Director’s New Innovator Awards for high-risk, high-reward research.

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To help break the cycle of mental illness, addiction and homelessness, The University of Texas Health Science Center at Houston (UTHealth) has launched a new integrated, trauma-informed behavioral health program for treatment and recovery support.

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Drinking an additional 1.5 liters of water daily can reduce recurring bladder infections in premenopausal women by nearly half, a yearlong study of otherwise healthy women with a history of repeated infections has found.

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A tumor-specific vaccine combined with an immune checkpoint inhibitor shrank tumors in one third of patients with incurable cancer related to the human papilloma virus (HPV) in a phase II clinical trial led by investigators at The University of Texas MD Anderson Cancer Center and reported in JAMA Oncology.

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Houston Methodist Cancer Center has expanded its basic cancer research program, cancer prevention and control efforts, and surgical oncology services with the addition of two national recruits.

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A novel therapy technique invented by researchers at The University of Texas at Dallas has been shown in a pilot study to double the rate of upper limb recovery in stroke patients, a leap forward in treating the nearly 800,000 Americans who suffer strokes each year.

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The University of Texas Health Science Center at Houston (UTHealth) will be part of a new genome center, one of just three created nationally with $28.6 million in funding from the All of Us Research Program of the National Institutes of Health (NIH).

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Previous research has shown that violent crimes are associated with greater access to alcohol outlets. It is unclear, however, whether on-premise outlets such as bars, or off-premise outlets such as liquor stores, have a stronger association with violent crimes. This study used more precise measurement of outlet locations to examine associations between violent crimes and access to different types of alcohol outlets in Baltimore, Maryland.

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Racial and ethnic discrimination is problematic for all aspects of development — from mental and physical health to risky behaviors and academic success — particularly for Latinos, researchers at The University of Texas at Austin determined after analyzing findings from hundreds of previous studies on adolescents.

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A study that reviewed genetic testing results from 1.45 million individuals found that nearly 25 percent of “variants of uncertain significance” were subsequently reclassified – sometimes as less likely to be associated with cancer, sometimes as more likely.

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The Susan G. Komen organization has awarded a $600,000 research grant to Dr. Carlos Arteaga, Director of the Harold C. Simmons Comprehensive Cancer Center and Associate Dean of Oncology Programs at UT Southwestern Medical Center.

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Associate Professor James Scott to speak Sept. 26 about the core concepts behind artificial intelligence by exploring the history of the ideas that led to its development.

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A drug revived by researchers at The University of Texas MD Anderson Cancer Center continues to provide unprecedented response rates among stage 4 non-small cell lung cancer patients with genetic mutations that have previously defied treatment.

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Living with Huntington’s disease can often feel like an endless battle, but patients and their families had the time of their lives watching the Houston Astros in action at Minute Maid Park.

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The University of Texas MD Anderson Cancer Center today joined with more than 450 communities and institutions across the country in hosting a Biden Cancer Community Summit, organized under the charge of the Biden Cancer Initiative. The Summit aims to encourage an ongoing dialogue about opportunities to make significant advances in cancer research, prevention, diagnosis and care.

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The family’s hope for Willow stems from a gene therapy center at UT Southwestern Medical Center where leading experts are engineering innovative treatments for some of the world’s rarest brain diseases.

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New opportunities such as seed production are leading to new research in the Texas A&M AgriLife Research high tunnel project near Bushland.

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Adding more evidence to the comparison between radiation therapy and surgery in treating an increasingly diagnosed head and neck cancer, a new study by researchers at UT Southwestern Medical Center found no major long-term differences in the effectiveness of the two therapies.

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By 2021, Texas Tech University Health Sciences Center El Paso expects to open its fourth school, the Woody L. Hunt School of Dental Medicine. Once approved, the WLHSDM will make history as West Texas’ first-ever dental school. To learn what this means for the university, and for the Paso del Norte region, we sat down with WLHSDM Dean Richard C. Black, D.D.S., M.S., who has also served as interim dean since 2017.

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UT Southwestern researchers today report the first use of CRISPR genome-wide screening to identify a gene that helps cells resist flavivirus infection.

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The risks of alcohol consumption differ by the presence or absence of simultaneous use of other substances, the most common one being marijuana. Simultaneous alcohol and marijuana use may increase alcohol-related risks and societal costs. This paper examined historical changes in simultaneous alcohol/marijuana use among young adult alcohol users from 1977 – 2016.

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Bereaved children whose late mothers were very religious are likely to be less religious after their mother dies than those who do not suffer a maternal loss. Conversely, youths whose late mothers placed no value on religion are more likely to become religious.

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A professor at UTHealth in Houston is testing the hypothesis that probiotics can help improve gastrointestinal symptoms of children with autism spectrum disorder (ASD).

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The Cancer Prevention and Research Institute of Texas (CPRIT) has awarded more than $37 million to UT Southwestern for cancer research and prevention.

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Padmanee Sharma, M.D., Ph.D., professor of Genitourinary Medical Oncology and Immunology at The University of Texas MD Anderson Cancer Center, has been recognized for her innovative work understanding factors that enhance and hinder cancer immunotherapy. Sharma will receive the William B. Coley Award for Distinguished Research in Tumor Immunology, awarded annually by the Cancer Research Institute (CRI), at an annual meeting co-sponsored by CRI in New York Sept. 30 to Oct. 3.

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Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a form of cell death called ferroptosis, opening up a potential new area of therapy research. Findings from the study, led by Boyi Gan, Ph.D., associate professor, Department of Experimental Radiation Oncology, were published in the Sept. 10 online issue of Nature Cell Biology.

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The University of Texas at El Paso, with a consortium of more than 40 other institutions and organizations from the public and private sector, is at the forefront of a national effort to increase the number of Hispanic students who participate in computing.

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Teens who took a supplemental drivers’ education program — including tours of emergency rooms, ICUs and a morgue — showed more awareness of the consequences of risky driving and of how they can avoid dangers, but whether that will change their driving is inconclusive, researchers say.

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Parents always worry about whether their children will do well in school, but their kids probably were born with much of what they will need to succeed.

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Small, New World monkeys called marmosets can mimic the sleep disturbances, changes in circadian rhythm, and cognitive impairment people with Parkinson’s disease develop, according to a new study by scientists at Texas Biomedical Research Institute.

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The FSMB Foundation – the philanthropic arm of the Federation of State Medical Boards - has widened its grantmaking with a new program that supports the work of diverse research and educational projects through “mini-grants” of up to $5,000 each. The grants are designed to encourage research or educational efforts that increase awareness and understanding of trends and issues impacting medical regulation, as well as patient safety and health care quality overall.

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Having atrial fibrillation (AFib) can increase your risk for stroke and heart failure. It’s vital to know your risk and get help before it strikes.

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Pediatric epilepsy specialists are rare; children with epilepsy are not. So in 2005, the British Paediatric Neurology Association established a training course for all health care professionals to improve pediatric epilepsy care around the world.

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An easy and inexpensive test could one day allow clinicians to quickly identify epilepsy patients at risk of carbamazepine hypersensitivity. The technology can be customized to other alleles and is applicable to other gene diagnostics, including pathogen detection.

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Scientists for the first time have used CRISPR gene editing to halt the progression of Duchenne muscular dystrophy (DMD) in a large mammal, according to a study by UT Southwestern that provides a strong indication that a lifesaving treatment may be in the pipeline.

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Heart attack patients given a different type of breathing tube by paramedics had better survival rates than those treated by traditional intubation breathing tube methods – findings that could potentially save more than 10,000 lives annually, researchers report.

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A team of investigators used intraoperative infusions of labeled glucose in patients about to have surgery to remove the kidney cancer to assess how the tumors use glucose.

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UT Southwestern is one of the few medical centers in the country – and the first in Texas – to put the magnetic surgery device to use.

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Scientists at The University of Texas at El Paso have received nearly $6 million from the National Institutes of Health (NIH) to improve treatment and develop new diagnostic tools to assess post-therapeutic outcomes for patients with Chagas disease.

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A Texas Tech University Health Sciences Center El Paso initiative that is increasing the number of screenings for colorectal cancer across West Texas has caught the eye of the National Cancer Institute.

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Biological anthropologists from The University of Texas at Austin have described three new species of fossil primates that were previously unknown to science.

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Blackouts refer to partial or complete memory loss of events that occur while individuals are drinking. These individuals maintain consciousness during the event and may even be able to engage in complex behaviors such as conversing or driving. This study examined young adults’ perceptions of complete memory loss (“en bloc”) blackouts, and off-and-on memory loss (fragmentary) blackouts.

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Young adults who report mistreatment (‘maltreatment’ by the authors) during childhood often demonstrate poor decision-making skills and are at risk for developing alcohol or other drug (AOD) problems, in particular when around peers. Research suggests that decision-making depends on a person’s ability to regulate him/herself during socially stressful situations. This study examined relationships between child mistreatment and AOD problems, with a focus on lack of self-regulation by the young adults as a key risk factor.

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A new device allows surgeons to create an access point for dialysis patients using a minimally-invasive approach. This might help the more than 470,000 currently on dialysis.

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Transplant surgeons are testing a new device that keeps the liver warm and circulates blood through its vessels during transport.

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In a study published today in Science, UT Southwestern and Rockefeller University researchers used advanced microscopes to determine at atomic resolution the structure of a molecular complex implicated in birth defects and several cancers.