Heather Wojcik, Harold N Lovvorn, Melinda Hollingshead, Janene Pierce, Howard Stotler, Andrew J Murphy, Suzanne Borgel, Hannah M Phelps, Hernan Correa, Alan O Perantoni
When starved of glucose, yeast kills its own clones and other surrounding microorganisms to survive in a newly discovered phenomenon named latecomer killing.
Sophie Girardin, Stephan Johannes Ihle, Arianna Menghini, Magdalena Krubner, Leonardo Tognola, Jens Duru, Tobias Ruff, Isabelle Fruh, Matthias Muller, János Vörös
Tailoring the analysis of whole genome sequencing to individual patients could double the diagnostic rates of rare diseases, finds a new study led by UCL researchers.
Insulin injections to treat Type 1 diabetes could become a thing of the past, but finding the cure faces many challenges. Although transplanting insulin-producing cells represents a promising approach, this cell therapy requires immunosuppression to prevent rejection. Georgia Tech researchers have developed a new biomaterial called iTOL-100 that could cure Type 1 diabetes by inducing immune acceptance of curative transplanted cells without immunosuppression.
Dennis Kruk, Anna Yeung, Alen Faiz, Nick H.T. Ten Hacken, Wim Timens, Toin H. Kuppevelt, Willeke Daamen, Danique Hof, Martin C. Harmsen, Mauricio Rojas, Irene H. Heijink
Oier Pastor-Alonso, Irene Dura, Sara Bernardo-Castro, Emilio Varea, Teresa Muro-Garcia, Soraya Martin-Suarez, Juan Manuel Encinas-Perez, Jose Ramon Pineda
Researchers at Cornell University have come up with a reliable, skin-tight computing system that’s easy to attach and detach, and can be used for a variety of purposes – from health monitoring to fashion.
Glioblastomas are lethal malignancies that possess a rapidly evolving microenvironment containing necrotic/hypoxic areas, aberrant microvasculature, and glioblastoma stem cells (GSCs) that promote tumor growth, recurrence, and treatment resistance. C
The reciprocal regulation between mesenchymal stem/stromal cells(MSCs)and immune responses is complex and critical for designing cell therapies. Wang et al. discuss the characteristics and functions of MSCs under different pathophysiological cond
Zheng et al. provide a transcriptomic landscape of hematopoietic stem and progenitor cells and microenvironment in human fetal bone marrow and spleen. They uncover the precise timepoint at which hematopoietic stem cells (HSCs) seed fetal bone marrow
Su et al. performed single-nucleus RNA-sequencing analysis to map diversity, molecular properties, disease relevance, and age-dependent dynamics of glial subpopulations in the human hippocampus across the postnatal lifespan. The resulting glial refe
Collecting ducts in the kidney control the balance of water and electrolytes, as well as pH of the urine to maintain body homeostasis. Shi et al.1 recently reported in Nature Biotechnology a protocol to generate functional collecting duct cells from
A recent study1 demonstrates how hematopoietic stem cells (HSCs) contribute minimally to blood and immune cell production during development and only become active postnatally. The work also reveals how Mecom expression can be used to distinguish rar
Bowel cancer patients could in future benefit from a new 3D bioprinting technology which would use their own cells to replicate the complex cellular environment of solid tumours in 3D models. The University of Bristol-led advance, published in Biofabrication, would allow clinicians to treat the models, known as spheroids, with chemotherapy drugs and radiation to help them understand an individual patient’s resistance to therapies.
Leading culture collection networks in the EU and the U.S. announced today the signing of a Memorandum of Understanding to enhance their cooperation to promote microbial resources and innovation in biotechnology.
Canadian chemists specializing in nanotechnology draw inspiration from nature to create molecular transporters that optimize the release of therapeutic drugs.
Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.
Microalgae play an important role in the Earth’s climate, converting carbon dioxide into solid carbon. This research sought new ways to study these microalgae and their associated bacterial communities across time and space. The researchers created a new co-culture method called a “porous microplate” that passes nutrients and molecules associated with metabolism between culture cells while blocking physical contact between algae in adjacent wells.
A new gene editing technique developed by University of Oregon researchers compresses what previously would have been years of work into just a few days, making new kinds of research possible in animal models.
Sang Hwa Kim, Kye D Nichols, Eric N Anderson, Yining Liu, Nandini Ramesh, Weiyan Jia, Connor J Kuerbis, Mark Scalf, Lloyd M. Smith, Udai Bhan Pandey, Randal S Tibbetts