Feature Channels: Pharmaceuticals

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Surgisphere Corporation announces the availability of a rapid diagnostic tool for novel coronavirus.

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Coriell Life Sciences (CLS), a leading provider of molecular test interpretation and reporting, is offering its coronavirus analysis and reporting services to laboratories throughout the United States at no cost during this period of public health crisis.

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More than 35 million Americans take statin drugs daily to lower their blood cholesterol levels. Now, in experiments with human cells in the laboratory, researchers at Johns Hopkins Medicine have added to growing evidence that the ubiquitous drug may kill cancer cells and have uncovered clues to how they do it.

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Genomic data donated by the public is valuable for the companies that collect it. But a recent survey finds that once people are aware of issues surrounding the use and security of genetic information, people are more concerned about how it might be used and expect to be better compensated for providing it.

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Delivering the medication dantrolene through the nose rather than the mouth may help the medication penetrate the brain more effectively, potentially maximizing its therapeutic benefits in the treatment of neurodegenerative diseases, like Alzheimer’s disease.

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Scientists at Washington University School of Medicine in St. Louis have developed a new imaging agent that could let doctors identify not only multiple types of tumors but the surrounding normal cells that the cancer takes over and uses as a shield to protect itself from attempts to destroy it.

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Drug resistance is a leading cause of cancer death in children and adults with leukemia. St. Jude Children’s Research Hospital scientists have developed a novel strategy to find the genes responsible.

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In a study to be published in the journal Nature Medicine, researchers report on using a skin cream infused with microscopic particles, named STAR particles, to potentially facilitate better treatment of skin diseases including psoriasis, warts, and certain types of skin cancer.

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In research published in Science Advances, Xavier Intes, a professor of biomedical engineering at Rensselaer, joined a multidisciplinary team from Northeastern University and the Icahn School of Medicine at Mount Sinai to demonstrate a methodology that combines the bioprinting and imaging of glioblastoma cells in a cost-effective way that more closely models what happens inside the human body.

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Collaboration combines Harbour BioMed’s proprietary H2L2 Harbour Mice® platform for fully human monoclonal antibody generation with Mount Sinai’s translational medical research expertise.

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In the study, a group of lab mice that had consumed a diet that included the HM-10/10 peptide was found to have a significantly lower tumor load than mice that had not eaten the peptide.

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New research data in the journal PLoS Pathogens suggests that reactivated HSV in trigeminal nerves of laboratory mice kills off at least a portion of sensory neurons. The findings provide additional evidence that as humans get older, the long-term consequences of HSV infection in the nervous system can accumulate and cause neurological damage.

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Researchers who discovered that an engineered cold sore virus could help destroy brain tumors from the inside out have determined a one-two punch might be the key to finish them off. This virotherapy could make a class of investigational cancer drugs more effective, according to investigators at UTHealth.

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The March 2020 issue of Toxicological Sciences features leading research in toxicology, covering investigations in biotransformation, toxicokinetics, and pharmacokinetics in addition to work in exposure sciences and environmental toxicology.

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Researchers from the School of Pharmacy at Queen’s University Belfast have developed a new antimicrobial coating which can be applied to urinary catheters and other medical devices to significantly reduce pain and lower the risk of infection for its users. This unique coating has the potential to greatly improve the quality of life for the millions of catheter users worldwide.

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For years, curry lovers have sworn by the anti-inflammatory properties of turmeric, but its active compound, curcumin, has long frustrated scientists hoping to validate these claims with clinical studies.

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Most birth control options rely on women to manage, but promising Cornell research from the lab of Paula Cohen may be changing the game by tackling male contraception.

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People with headache who use smartphones may be more likely to use more pain medication and find less relief when they do than people with headache who do not use smartphones, according to a preliminary study published in the March 4, 2020, online issue of Neurology® Clinical Practice, an official journal of the American Academy of Neurology. The study does not prove that smartphone use causes greater use of pain medication and less relief; it only shows an association.

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Many people think migraines are just bad headaches – but they’re so much more. While no cure for migraines exists, hope abounds thanks to major advances in research.

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Little data is available about the ability of antiviral drugs used to treat COVID-19, coronavirus, to enter breastmilk, let alone the potential adverse effects on breastfeeding infants.