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Researchers at the University of Illinois Chicago are a step closer to discovering why it is so difficult for people to withdraw from some antidepressant medications. The paper “Antidepressants produce persistent Gαs associated signaling changes in lipid rafts following drug withdrawal,” published in the journal Molecular Pharmacology, addresses the molecular and cellular mechanisms that cause antidepressant withdrawal syndrome.
o help increase access to the availability of non-opioid pain management treatments, the American Association of Nurse Anesthetists (AANA) supports the recent introduction of the Non-Opioids Prevent Addiction in the Nation (NOPAIN) Act introduced by U.S. Rep. Terri Sewell (D-AL), along with Reps. David McKinley (R-WV), Ann Kuster (D-NH), and Brian Fitzpatrick (R-PA). The Senate version of this legislation (S. 589) was previously introduced.
Now that a key policy regarding prescription of a medication for opioid use disorder has been changed, experts reflect on the remaining challenges standing in the way of more people getting effective medication-assisted treatment, and discuss efforts to overcome those barriers.
Researchers at University of California San Diego School of Medicine found that functional impairments among adults aged 50 and older are associated with a higher risk of medical cannabis use; and prescription opioid and tranquilizer/sedative use and misuse.
A study published in the scientific journal Addiction provides the most comprehensive evidence to date of the association between recreational cannabis laws (RCLs) in US states and responses in the illegal markets for cannabis, heroin, and other drugs in those states.
Amid the rising toll of opioid overdoses and deaths in the U.S., several states are considering laws enabling civil commitment for involuntary treatment of patients with substance use disorders (SUDs). Most addiction medicine physicians support civil commitment for SUD treatment – but others strongly oppose this approach, reports a survey study in Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine (ASAM). The journal is published in the Lippincott portfolio by Wolters Kluwer.
The partners of mothers-to-be can influence the women’s drinking and depression during pregnancy, affecting their babies’ development, a new study suggests. The findings highlight the importance of partners’ role in reducing risk for expectant mothers. Pregnant women’s behavioral health is known to be influenced by their relationships with their partners. Partners’ higher substance use, and women’s lower relationship satisfaction, are associated with higher maternal substance use. Women who feel supported by their partners, in contrast, report less prenatal anxiety and depression and lower postpartum distress. Drinking and depression during pregnancy are each associated with multiple health problems, such as premature birth and delayed infant development. The study in Alcoholism: Clinical & Experimental Research explores the role of partners, prenatal alcohol use, and infant outcomes together, aiming for a more comprehensive understanding of how these factors combine.
In a new study, clinician-researchers at Beth Israel Deaconess Medical Center (BIDMC) analyzed naloxone prescription trends during the COVID-19 pandemic in the United States and compared them to trends in opioid prescriptions and to overall prescriptions.
In a study of hundreds of patients undergoing total knee or hip replacement, researchers identified a gene called ABCB1 that may predict long-term pain and opioid use.
Neighborhoods without opioid treatment providers likely serve as a widespread barrier to care for those who are ready to seek help, a new study has found. Nearby access, including by public transit, is essential to treatment success, researchers say.
Programs that provide ongoing support to patients with painful conditions and complex medication regimens may also help them avoid using potentially risky opioid pain medications, or reduce the amount they use, a new study finds.
UC Davis researchers develop PsychLight, a sensor that could be used in discovering new treatments for mental illness, in neuroscience research and to detect drugs of abuse.
Researchers have created to novel biobanks of diverse tissues from animals to further explore the biological bases and consequences of addiction to cocaine and oxycodone.
Babies born to mothers diagnosed with cannabis use disorder are more likely to experience negative health outcomes, such as preterm birth and low birth weight, than babies born to mothers without a cannabis use disorder diagnosis, report UC San Diego researchers.
Since 2016, a federal regulation has allowed nurse practitioners and physician assistants to obtain a waiver to prescribe buprenorphine, a medication used to treat opioid use disorder as a medication assisted treatment.