The objective of the study was to evaluate the feasibility of sending supportive text messages to low-income mothers of racial and ethnic minority backgrounds with postpartum depression and gauge the perception of receiving such message for depression.
Pain is the most common reason that people seek medical attention, but the available treatments are not always successful at relieving pain in patients with chronic pain. Saint Louis University researchers found that drugs targeting the A3 adenosine receptor can “turn off” pain signals in the spinal cord to provide relief from chronic pain.
Transit stops close to home and workplace incentives are associated with higher likelihood that commuters will choose public transportation, according to research from the Brown School at Washington University in St. Louis and Washington University School of Medicine in St. Louis. The study is co-authored by Aaron Hipp, PhD, assistant professor at the Brown School.
Lesions in DNA can occur as often as 100,000 times per cell per day. They can be the result of normal metabolic activities, like free radicals, as well as exposure to environmental factors such as UV radiation, X-rays and chemical compounds. Saint Louis University researchers share a discovery that explains how cells use a process called replication fork reversal in order to deal with these roadblocks and transmit accurate genetic data.
A new study finds that that 1.2 percent of American preschool children on Medicaid are using psychotropic drugs, including antidepressants, mood stabilizers and medications for attention-deficit disorder. Using 2000-2003 Medicaid Analytic Extract data from 36 states, a group of researchers at the Brown School at Washington University in St. Louis and at Washington University School of Medicine in St. Louis found preschoolers are receiving psychotropic medications despite limited evidence supporting safety or efficacy.
The study cast doubts on the popular idea that salt consumption can help endurance athletes during competition.
New research led by Washington University School of Medicine in St. Louis shows that interfering with the replication of the Ebola virus can stop the virus in its tracks. The discovery opens the door to finding more effective treatments.
Nearly 40 percent of Americans 60 and older are living with a swallowing disorder known as dysphagia. Although it is a major health problem associated with aging, it is unknown whether the condition is a natural part of healthy aging or if it is caused by an age-related disease that has yet to be diagnosed, such as Parkinson’s disease or amyotrophic lateral sclerosis (ALS). Following a recent study, researchers at the University of Missouri have established a model that identifies aging as a key factor in the development of dysphagia, which may lead to new therapeutic treatments.
The federal health-care law has reduced the number of uninsured people by about 10 million. But challenges remain, including how to educate new enrollees about their coverage options. New research shows that communicating new, sometimes confusing information about the Affordable Care Act can be as simple as using plain language, providing comparisons to familiar contexts and using stories about how people might make health insurance decisions.
Introduced plants make up roughly half the diet of two subspecies of endangered tortoise, field research in the Galapagos reveals. Tortoises seem to prefer non-native to native plants and the plants may help them to stay well-nourished during the dry season.
A small team of chemists, having learned the secrets of light absorption from chlorophylls a and b, can now tune molecules to absorb anywhere in the solar spectrum. They are using this facility to synthesize pigments that fill gaps in the sunlight absorbed by native pigments and to push deeper into the infrared than any native pigment
Personalized melanoma vaccines can be used to marshal a powerful immune response against unique mutations in patients' tumors, according to early data in a first-in-people clinical trial at Washington University School of Medicine in St. Louis. The research is reported April 2 in Science Express.
In people, a baby’s risk of congenital heart defects is associated with the age of the mother. Risk goes up with increasing age. Newborn mice predisposed to heart defects because of genetic mutations show the same age association. A new study demonstrates that older mouse mothers reduce this risk for their offspring to that of younger mouse mothers through exercise alone, according to researchers at Washington University School of Medicine in St. Louis.
Using a new high-speed, high-resolution imaging method, Lihong Wang, PhD, and his team at Washington University in St. Louis were able to see blood flow and other functions inside a living mouse brain at faster rates than ever before.
Saint Louis University researcher Daniel Hawiger hopes that these breakthroughs will open the door to design better treatments for autoimmune diseases.
Computer scientists at Washington University in St. Louis tackled some big data about an important protein and discovered its connection in human history as well as clues about its role in complex neurological diseases.
A team of University of Missouri researchers has discovered that another nutrient in garlic offers the brain protection against aging and disease. The finding provides more understanding of how garlic may prevent age-related neurological diseases such as Alzheimer’s and Parkinson’s.
Antibiotic resistance is poised to spread globally among bacteria frequently implicated in respiratory and urinary infections in hospital settings, according to new research at Washington University School of Medicine in St. Louis.
When it comes to romantic relationships, a research review article by a Saint Louis University faculty member suggests humans are wired to break up and move on.
The industrial metal manganese, once scarce, is now ubiquitous in our environment. New work suggests that it addles honey bees, which often act as sentinel species for environmental contaminants, even at levels considered safe for humans.
Much has been written about the history of the women’s and gay liberation movements of the late 20th century, but little is known about how heterosexual men navigated dramatic changes in the legal regulation of families in the 1980s. In a new paper forthcoming in the Virginia Law Review (2016), Deborah Dinner, JD, PhD, associate professor of law at Washington University in St. Louis, provides the first legal history of the father’s rights movement, analyzing how middle-class white men responded to rising divorce rates by pursuing reform in both family law and welfare policy.
The outcome of a duel between mathematical models supports the reigning theory of the genetics of altruism. Called inclusive fitness, it says altruism is competitive if it benefits relatives carrying the same gene as the selfless individual. Attacked by a Nature article published in 2010, it is defended by Washington University evolutionary biologist David Queller.
Vitamin D deficiency is linked to type 2 diabetes and heart disease, and both disorders are rooted in chronic inflammation. Now, studying mice that lack the ability to process vitamin D in immune cells involved in inflammation, Washington University School of Medicine researchers found that the animals made excess glucose, became resistant to insulin action and accumulated plaques in their blood vessels. He said the way those key immune cells behave without vitamin D may provide new targets for treating diabetes and atherosclerosis patients.
If kidney cancer is diagnosed early — before it spreads beyond the kidney — 80 percent of patients survive. However, finding it early has been among the disease’s greatest challenges. Now, Washington University School of Medicine have developed a noninvasive method to screen for kidney cancer that involves measuring the presence of proteins in the urine.
A new project from the Center for Social Development at Washington University in St. Louis shows, among other findings, that girls in developing countries, given equal opportunities, will save as much or more in formal financial institutions than boys.
In diseases such as asthma and chronic obstructive pulmonary disease (COPD), the body produces too much mucus, making breathing difficult. New research from Washington University School of Medicine in St. Louis provides clues to potentially counteract inappropriate mucus production.
An endowed professorship in plastic surgery will boost research.
Saint Louis University recently received grant funding to tackle the health impacts of living without easy access to grocery stores and healthy foods.
Findings by a Saint Louis University researcher parallel earlier results: Adding a strain of influenza B could improve effectiveness of an influenza vaccine.
Appearing March 12 before the U.S. Senate Special Committee on Aging, Michal Grinstein-Weiss, PhD, associate director of the Center for Social Development (CSD) at Washington University in St. Louis, urged U.S. senators to create long-term asset-building policies and to use such “golden moments” as tax time to urge Americans to save.
Colorism, the practice of discrimination based on skin tone even among people of color, is rarely addressed publicly and is uniquely different from racism. The Whitney R. Harris World Law Institute at Washington University in St. Louis School of Law will address this growing international phenomenon in what organizers believe is the first international colorism conference on U.S. soil. The conference, “Global Perspectives on Colorism,” will be held Thursday and Friday, April 2 and 3, in Anheuser-Busch Hall.
Scientists are eager to make use of stem cells’ extraordinary power to transform into nearly any kind of cell, but that ability also is cause for concern in cancer treatment. A new study shows stem cells are found even in low-grade tumors, where they can resist treatment.
A reformulation of OxyContin that makes it less likely to be abused than the older formulation has curtailed the drug’s illicit use. But researchers at Washington University School of Medicine in St. Louis have found that a significant percentage still abuse the drug despite package labeling that emphasizes its abuse-deterrent properties.
C-STARS (Center for Sustainment of Trauma and Readiness Skills) is the first program in the country to prepare U.S. Air Force medical technicians, nurses and doctors to take care of traumatic injuries to patients during war time.
Isotopic analysis of animal teeth from a 2,000-year-old herding settlement near Lake Victoria in southern Kenya show the area was once home to large grassland corridors — routes that could have been used to dodge tsetse flies and bring domesticated livestock to southern Africa, according to new research in the journal Proceedings of the National Academies of Science.
Researchers at the Stowers Institute for Medical Research have developed a high-resolution method that can precisely and reliably map individual transcription factor binding sites in the genome, vastly outperforming standard techniques
Using a mouse model of cancer, researchers at Washington University School of Medicine in St. Louis have devised a way to apply light-based therapy to deep tissues never before accessible. Instead of shining an outside light, they delivered light directly to tumor cells, along with a photosensitive source of free radicals that can be activated by the light to destroy cancer. And they accomplished this using materials already approved for use in cancer patients.
With the “Right to Work” movement growing in Wisconsin and other states, a majority of states may soon bar employees and unions from negotiating agreements that require non-members to contribute to the costs of representing them. For unions to survive and thrive, at least two significant changes are necessary, argues Marion Crain, JD, vice provost and the Wiley B. Rutledge Professor of Law at Washington University in St. Louis.
While many Americans took a big financial hit during the Great Recession, homeowners were less likely than renters to lose very large proportions of their wealth, finds a new study from Michal Grinstein-Weiss, PhD, associate director of the Center for Social Development in the Brown School at Washington University in St. Louis.
SLU sleep specialist recommends a gradual approach to 'springing' forward' for Daylight Saving Time.
The stigma surrounding people with severe mental illness in India leads to increased poverty among them, especially women, according to new research led by Jean-Francois Trani, PhD, assistant professor at the Brown School at Washington University in St. Louis.
Evaluating military personnel with blast-related mild traumatic brain injuries, researchers have found that early symptoms of post-traumatic stress, such as anxiety, emotional numbness, flashbacks and irritability, are the strongest predictors of later disability. The results were surprising because mental health more closely correlated with disability than assessments typically made after concussions, such as tests of memory, thinking, balance, coordination and severity of headaches and dizziness, according to the study led by Washington University School of Medicine in St. Louis.
New research suggests that widely used statin therapy provides the most benefit to patients with the highest genetic risk of heart attack. Using a relatively straightforward genetic analysis, the researchers assessed heart attack risk independently of traditional risk factors such as age, sex, so-called good and bad cholesterol levels, smoking history, family history and whether the patient has diabetes.
Highlighting a potential target in the treatment of multiple sclerosis (MS) and Alzheimer’s disease, new research suggests that triggering a protein found on the surface of brain cells may help slow the progression of these and other neurological diseases.
Every March, students at Missouri University of Science and Technology wield wooden walking sticks called shillelaghs to rid the campus of rubber snakes in honor of how, according to legend, St. Patrick drove the snakes from Ireland centuries ago. This year students, alumni and other visitors to the university’s website will be able to join in on the fun.
Jianmin Cui, PhD, has received a nearly $1.7 million grant from the National Institutes of Health to study the molecular bases for the function of potassium channels vital for the heart, brain, inner ear and other tissues.
An investigational drug appears to cut the risk of severe asthma attacks in half for patients who have difficulty controlling the disorder with standard medications, according to results from two multicenter clinical trials headed by Mario Castro, MD, an asthma specialist at Washington University School of Medicine in St. Louis.
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