Modification of Common Diabetes Drug Improved Blood Sugar Control in Mouse Model
American Physiological Society (APS)
A team of researchers has established a ribonucleic acid (RNA)-based method that drives cells in the body to produce therapeutic proteins and secrete them into the bloodstream. The approach could potentially extend the lifespan of drugs in the body, reducing the burden on patients who require frequent drug administrations.
According to new research looking at every U.S. state, programs that deliver medically tailored meals (MTMs) to people with diet-sensitive conditions such as diabetes and heart disease along with limitations in the ability to perform daily activities could lead to substantial savings in healthcare costs.
For patients with severe obesity undergoing knee or hip replacement, commonly obtained laboratory values – including markers of anemia and inflammation – are independent predictors of the risk of periprosthetic joint infection (PJI), reports a study in The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Eating patterns that align with the Mediterranean diet or the dietary approaches to stop hypertension (DASH) diet could help lower cardiovascular disease risk in adults with type 1 diabetes, according to results from a six-year study.
Findings from a new mouse study suggest that elenolic acid, a natural compound found in olives, can lower blood sugar levels and promote weight loss. The research could pave the way to the development of safe and inexpensive natural products for managing obesity and type 2 diabetes in people.
See how St. Jude researchers investigated Foxp3 function as a transcription cofactor in regulatory T cells in immune system activation and suppression.
A genetic variation common in people of African ancestry is associated with an increased risk of complications from diabetes, including diabetic retinopathy, according to a report published June 25 in the journal Nature Medicine.
Researchers from Johns Hopkins Medicine and the National Institutes of Health’s National Institute on Aging say their study of 40 older adults with obesity and insulin resistance who were randomly assigned to either an intermittent fasting diet or a standard healthy diet approved by the U.S. Department of Agriculture (USDA) offers important clues about the potential benefits of both eating plans on brain health.
A weekly dose of semaglutide 2.4 mg significantly reduced the risk of major adverse cardiovascular events (MACEs) in people with overweight or obesity and cardiovascular disease but not diabetes, regardless of blood sugar level, according to a clinical trial including researchers from UT Southwestern Medical Center. The findings, published in Diabetes Care, also show the reduction in MACEs – a combination of heart attacks, stroke, or death from cardiovascular causes – isn’t due to the drug’s effect in lowering blood sugar.
Hospitalized patients with complex dietary restrictions often develop hyperglycemia (high blood sugar), leading to serious complications particularly in those with preexisting diabetes. UCSF endocrinologist Robert J. Rushakoff, MD, and his team developed a self-adjusting subcutaneous insulin algorithm (SQIA) for automatically adjusted dosing.
UC San Diego School of Medicine international study shows new drug improves sleep, health in patients diagnosed with obesity and sleep apnea.
A study by researchers at Washington University School of Medicine in St. Louis shows that people with COVID-19 who used cannabis were more likely to be hospitalized and require intensive care than those who did not use the drug.
Your sleep tracker might give you information about more than just your sleep–specifically, it might give you information about chronic conditions such as diabetes and sleep apnea, and illnesses such as COVID-19. This is one of the findings of a study that analyzed data from 5 million nights of sleep across roughly 33,000 people.
Poor diet continues to take a toll on American adults. In a study from the Food is Medicine Institute at the Friedman School of Nutrition Science and Policy at Tufts University published today in the Annals of Internal Medicine, researchers found that diet quality among U.S. adults improved modestly between 1999 and 2020. However, they also found that the number of Americans with poor diet quality remains stubbornly high. Most notably, disparities persist and, in some cases, are worsening.
In a large clinical trial, UT Southwestern Medical Center researchers developed a robust model for testing strategies to prevent health problems in patients with multiple chronic conditions.