Focus: Hidden - Pennsylvania

• share
• favorite_border

Experts say it's always better to get the flu vaccine than not.

• share
• favorite_border

A novel synthetic DNA vaccine developed based on technology pioneered by Wistar scientists offers complete protection from Zaire Ebolavirus (EBOV) infection in promising preclinical research.

• share
• favorite_border

Doctors, nurses and clinical staff will lead efforts to transform the electronic health records at Penn Medicine, recognizing them as a tool just as important as scalpels to modern health care delivery.

• share
• favorite_border

A UPMC-developed test for diagnosis of thyroid nodules, ThyroSeq® Genomic Classifier, has been approved for coverage by its Medicare Administrative Contractor, Novitas Solutions. This decision paves the way for the test to be accessible to more than 50 million Medicare patients nationwide.

• share
• favorite_border

Pediatric researchers studying the life-threatening blood disorder Fanconi anemia have devised a method to block the abnormal biological signals that drive the disease. This proof-of-concept finding in animals and stem cells may lay the foundation for better treatments for children with the rare, frequently fatal disease.

• share
• favorite_border

A team of clinicians, dietitians and researchers has created an automated program to screen for malnutrition in hospitalized children, providing daily alerts to healthcare providers so they can quickly intervene with appropriate treatment. The malnutrition screen draws on existing patient data in electronic health records (EHR).

• share
• favorite_border

New NCCN Guidelines for Patients: NET provides background and treatment information for neuroendocrine tumors, the type of cancer experienced by Aretha Franklin and Steve Jobs

• share
• favorite_border

Contrary to long-held assumptions, researchers find that some seizures start after a burst from neurons that inhibit brain activity.

• share
• favorite_border

On Saturday afternoon, Judge Brett Kavanaugh was confirmed to the Supreme Court by a 50-48 vote in the Senate, almost strictly along party lines. Marked by allegations of sexual assault and sustained partisan acrimony

• share
• favorite_border

For the first time, scientists have performed prenatal gene editing to prevent a lethal metabolic disorder in laboratory animals, offering the potential to treat human congenital diseases before birth.

• share
• favorite_border

For the first time, scientists have performed prenatal gene editing to prevent a lethal metabolic disorder in laboratory animals, offering the potential to treat human congenital diseases before birth. The research offers proof-of-concept for prenatal use of a sophisticated, low-toxicity tool that efficiently edits DNA building blocks in disease-causing genes.

• share
• favorite_border

A new method for sequencing the chemical groups attached to the surface of DNA is paving the way for better detection of cancer and other diseases in the blood.

• share
• favorite_border

Wistar scientists have unraveled a mechanism of resistance to EZH2 inhibitors in ovarian cancers with mutations in the ARID1A gene.

• share
• favorite_border

The Cancer Patient Education Network (CPEN) honored the Patient Education Team from Penn Medicine’s OncoLink with the 2018 Excellence in Patient Education Award.

• share
• favorite_border

Scientists using a powerful new technology that sequences RNA in 20,000 individual cell nuclei have uncovered new insights into biological events in heart disease. In animal hearts, the researchers identified an array of cell types and investigated the “transcriptional landscape” in rich detail.

• share
• favorite_border

Crops being irrigated with an overhead irrigation system.10/03/2018By Jennifer MatthewsUNIVERSITY PARK, Pa. – Global sustainability is important now more than ever due to increasing urban populations and the resulting stress it can have on natural resources. But increased populations in cities may lead to greater efficiency, as a team of Penn State researchers discovered when they analyzed the water footprint of 65 mid- to large-sized U.

• share
• favorite_border

Wistar scientists and collaborators demonstrate for the first time that through engineering constructs, they can express DNA-encoded monoclonal antibodies (DMAbs) targeting CTLA-4, an important cancer checkpoint molecule that blocks anti-cancer immunity.

• share
• favorite_border

Temple University Beasley School of Law has announced a new gift of $1.5 million to the law school from the Sheller Family Foundation in support of the Sheller Center for Social Justice, bringing the Sheller Foundation’s total commitment to the Center to $3 million.

• share
• favorite_border

Penn Medicine experts in nephrology and health policy call for more transparency about joint-venture ownership of dialysis clinics to better understand what impact these arrangements may have on patient referrals and clinical outcomes. The lack of transparency poses a major barrier for evidence-based health care policy research and deprives patients of critical information, the researchers write in a new Perspective published in the New England Journal of Medicine.

• share
• favorite_border

It’s bad enough that breast cancer attacks physical health, but it can also take a toll on mental health and overall wellness.

• share
• favorite_border

Congenital muscular torticollis (CMT) is a common postural deformity in infants, and one that can be effectively treated by physical therapy. A set of updated, evidence-based recommendations for physical therapy management of CMT is presented in the October issue of Pediatric Physical Therapy. The journal is published in the Lippincott portfolio by Wolters Kluwer.

• share
• favorite_border

The medical conference is organized by the Sbarro Health Research Organization (SHRO), in collaboration with Temple University’s College of Science and Technology, the National Italian American Foundation (NIAF), and the Giovan Giacomo Giordano Foundation

• share
• favorite_border

A technique using umbilical cord blood stem cells could be a promising new approach for repair of cleft palate in infants, reports a paper in The Journal of Craniofacial Surgery, published in the Lippincott portfolio by Wolters Kluwer.

• share
• favorite_border

Roy A. Jensen, MD, is the new president of the Association of American Cancer Institutes. He began his two-year term today at the close of the AACI/CCAF annual meeting in Chicago. Dr. Jensen announced plans to develop a comprehensive, cancer-specific library of model legislation.

• share
• favorite_border

The National Institutes of Health grant supports a collaboration between Temple University's dentistry and psychology researchers

• share
• favorite_border

Splitting up and getting back together is always hard to do, but for proteins, it's almost impossible. However, a computer-guided algorithm may help scientists find just the right spot to split a protein and then reassemble it to functionality.

• share
• favorite_border

Three Pitt faculty members win highly selective NIH awards supporting high-risk, high-reward research projects

• share
• favorite_border

Wolters Kluwer, Health announced today that Novant Health is utilizing the Lippincott® Solutions suite to advance its wide-ranging quality improvement initiatives focused on standardizing care across 15 acute care hospitals and medical centers in four U.S. states. By equipping nurses with readily available evidence-based decision support and clinical education resources, Lippincott Solutions plays an important role in helping Novant Health facilities maintain Magnet Recognition®.

• share
• favorite_border

A new National Institutes of Health (NIH) High-Risk, High-Reward grant will allow Penn State’s Dr. Steven Schiff and team to explore a radically changed approach to predicting, preventing and treating infectious disease at the individual level at point-of-care.

• share
• favorite_border

Penn Medicine's new Molecular Integration in Neurological Diagnosis Initiative brings the power of precision medicine to Parkinson’s disease research.

• share
• favorite_border

Foundation Awards Presented for Ethics and Creativity in Medical Research, and Societal Impact in Business & Biotechnology

• share
• favorite_border

Placement of nasogastric (NG) tubes (feeding tubes) in pediatric patients is a common practice, however, the insertion procedure carries risk of serious or even potentially lethal complications. While there are numerous methods of verifying an NG tube has been placed correctly, none of those methods are considered universally standard.

• share
• favorite_border

A practice whose providers are known for a 35-year tradition of providing community-focused family medicine services to Berks and Schuylkill County residents is now part of Penn State Health Medical Group.

• share
• favorite_border

Sexual Harassment and Assault Linked to Worse Physical and Mental Health Among Midlife Women

• share
• favorite_border

A special November issue of Health Physics journal presents 13 original research papers, reviews, and commentaries related to women’s contributions to and experiences in radiation protection and safety. Health Physics, the official journal of the Health Physics Society (HPS) is published in the Lippincott portfolio by Wolters Kluwer.

• share
• favorite_border

An Ivy League experimental rule that moved the kickoff line from the 35- to the 40-yard line and the touchback line from the 25- to the 20-yard line reduced the average annual concussion rate by more than 68 percent, according to the research conducted by a team from The Ivy League and Perelman School of Medicine at the University of Pennsylvania.

• share
• favorite_border

Maybe the genetic test report your doctor ordered says your DNA contains many “variants of unknown significance.” But suppose at a later date a researcher discovers one of those changes causes a disease? How will you learn this new piece of information? You can’t even be sure your doctor will find out about it.

• share
• favorite_border

By investigating how genetic variations drive the expression of genes within the filtering cells of the kidney, researchers have found new pathways to explain CKD development and could inform its treatment.

• share
• favorite_border

The Thomas D. Larson Pennsylvania Transportation Institute (LTI) today announced that Leslie S. Richards, Pennsylvania Secretary of Transportation, will serve as keynote speaker at the 24th Annual Transportation Engineering and Safety Conference (TESC), to be held December 5-7, 2018, at The Penn Stater Hotel and Conference Center. Richards is scheduled to speak on December 5, between noon and 1:15 p.m.

• share
• favorite_border

In a study examining the potential impact of 2001-02 Medicaid expansions by Arizona, Maine and New York – expansions that occurred just prior to the rise in overdose mortality nationwide – researchers from the Perelman School of Medicine at the University of Pennsylvania found that from the time of these expansions through 2008, overdose mortality rates (mostly driven by fatal overdoses of opioids) rose significantly less in the expansion states than in non-expansion states.

• share
• favorite_border

Snow days at Penn State may have become even more rare, thanks to the work of a recent industrial engineering graduate.

• share
• favorite_border

A total of $475K in prizes was awarded to teams of budding entrepreneurs with the best ideas around improving human performance.

• share
• favorite_border

Wistar scientists have implemented a novel structurally designed synthetic DNA vaccine to simultaneously target multiple members of a family of proteins that are specifically overexpressed in several types of cancer.

• share
• favorite_border

There is an ongoing need for healthy volunteers in clinical research studies that can lead to healthcare breakthroughs that provide better drugs and treatments for patients.

• share
• favorite_border

Persistent and significant health disparities related to sexual health, including a higher teen birth rate and HIV prevalence, exist among Puerto Rican adolescents compared to other racial and ethnic adolescents. The Internet is a major platform for the dissemination of health information and has the potential to decrease health disparities and provide quality, culturally sensitive health information to disadvantaged populations.

• share
• favorite_border

In low-resource countries without well-developed screening programs, expanding access to human papilloma virus (HPV) vaccination is the best means of preventing cervical cancer and other diseases caused by HPV infection, according to an editorial in the October special issue of the Journal of Lower Genital Tract Disease, official journal of ASCCP. The journal is published in the Lippincott portfolio by Wolters Kluwer.

• share
• favorite_border

National Comprehensive Cancer Network (NCCN) moves into new global headquarters in Plymouth Meeting, PA, in the Greater Philadelphia area, less than three hour's drive from Washington, D.C., New York City, and Princeton, NJ.

• share
• favorite_border

Severe weather events, such as summer hurricanes, tornadoes, and winter snow storms often result in widespread and prolonged power outages, interrupting essential household functions, including home heating. In such a scenario, people may use generators and risk carbon monoxide poisoning.

• share
• favorite_border

A new Philadelphia-based start-up, Virion Therapeutics, LLC spun out of The Wistar Institute, will work to advance innovative, immune-based therapies for the treatment of chronic viral-associated cancers and viral infections utilizing the first genetically encoded checkpoint inhibitor that can be given via vaccination.

• share
• favorite_border

Saurabh Basu, assistant professor of industrial and manufacturing engineering, is working on making additive components more reliable thanks to a grant from the National Science Foundation.