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Released: 4-Apr-1998 12:00 AM EST
Enlarged Hearts and Mild Hypertension A Potentially Deadly Combination
American Society of Hypertension (ASH)

The combination of an enlarged heart and delays in the heart's electrical activity can be life threatening for people with borderline or mild high blood pressure, but the problem can be corrected with high blood pressure medications, according to a landmark study published in the American Journal of Hypertension.

Released: 4-Apr-1998 12:00 AM EST
University of Iowa researchers propose a model to explain the spread of an eye cancer
University of Iowa

Scientists don't know exactly how cancer spreads throughout the body or why some forms of the disease distribute to specific organs, but research conducted at the University of Iowa sheds new light on the mysteries of metastasis.

Released: 4-Apr-1998 12:00 AM EST
Conjoined or "Siamese twins": To separate or not to separate?
Michigan State University

When conjoined twins, or what's commonly known as "Siamese twins," are born, it's automatically assumed they should be separated. Right? Wrong, says a Michigan State University medical historian.

Released: 3-Apr-1998 12:00 AM EST
Sex Offenders Not as Likely to Relapse as Thought
American Psychological Association (APA)

Many believe that once a sex offender, always a sex offender. Not necessarily. According to 61 studies, less than 20 percent of sex offenders are found to have committed another sexual offense. Deviant sexual preferences, criminal lifestyle and dropping out of treatment were the biggest risk factors for reoffending.

Released: 3-Apr-1998 12:00 AM EST
Emory Doctors Use Quick, Painless Procedure To Reduce Habitual Snoring
Emory University Woodruff Health Sciences Center

Using a painless new procedure performed in 10 minutes, otolaryngologists at Emory University are restoring a restful night's sleep to habitual snorers and their loved ones.

Released: 2-Apr-1998 12:00 AM EST
New Studies on Domestic Violence, Organ Donation, and Reasons People Don't Stop to Help Motor Vehicle Crash Victims
American College of Emergency Physicians (ACEP)

Domestic violence reports to police did not increase following a 1994 California mandatory domestic violence reporting law, according to the April issue of Annals of Emergency Medicine. The journal also presents new studies on domestic violence screening, how alcohol abuse history is a strong predictor for acute injury from domestic violence, and the success of a program that increased organ donation referrals by 100 percent.

Released: 2-Apr-1998 12:00 AM EST
University of Illinois at Chicago Study Finds Outpatient Asthma Care Saves Money, Gets Results
University of Illinois Chicago

University of Illinois at Chicago researchers have found that a new treatment alternative for people suffering from severe asthma attacks is more effective and much less costly than traditional hospital inpatient care. Researchers estimate that the alternative treatment, known as an emergency department observation unit, costs $1,202 per patient compared with $2,247 per patient for inpatient care -- a drop of 47 percent.

Released: 2-Apr-1998 12:00 AM EST
Tiny Worm Reveals Workings of Suspected Tumor Protein
Harvard Medical School

The tiny worm that has become a darling of developmental biologists has revealed a biological function for a mysterious protein that may play a role in the growth of tumors. In the cover article of the April 1 Genes and Development, Yang Shi, HMS associate professor of pathology, reports that the worm's version of the human protein p300 helps cells in the early embryo decide what kind of tissue to become. Shi found that p300 also is critical for determining the number of cells formed in the embryo. His finding validates earlier cell culture experiments on how viral cancer-causing proteins subvert a cell's growth.

2-Apr-1998 12:00 AM EST
Women may be at higher risk than men of stroke and post-operative death following carotid endarterectomy
American Heart Association (AHA)

DALLAS, April 3 -- Women and certain other groups of patients who undergo carotid endarterectomy -- a common procedure used to clear blockages in the blood vessels to the brain -- may have a higher risk for death or stroke following the surgery, according to a study in this month's Stroke: Journal of the American Heart Association.

2-Apr-1998 12:00 AM EST
Stroke survivors can fare well into older age, study shows
American Heart Association (AHA)

DALLAS, April 3 -- Stroke survivors have the potential to live independent lives into their 80s and 90s just as well as people of the same age and sex who have not had a stroke, according to a study in this month's Stroke: Journal of the American Heart Association.

Released: 1-Apr-1998 12:00 AM EST
Study Finds Some People Are 'Born To Smoke'
University of Michigan

New research shows mounting evidence that some people are "destined" to become smokers because they are inherently more sensitive to the effects of nicotine than people who are not tempted to smoke again. These findings suggest how one in three kids who sample a cigarette will become lifetime tobacco customers.

Released: 1-Apr-1998 12:00 AM EST
New study provides more evidence that copaxone an slow progression of multiple sclerosis and reduces attacks
University of Maryland Medical Center

A study published today in the March issue of the journal Neurology provides more evidence that the medication Copaxone, the only non-interferon treatment for multiple sclerosis, reduces the number of relapses and slows the progression of disability. The study is a one-year extension of research at 11 medical centers in the United States.

Released: 1-Apr-1998 12:00 AM EST
Molecular Defect Could Be Mysterious Cause of Blood Disorder
Johns Hopkins Medicine

A unique molecular defect in an unusual blood disorder first identified and described at Johns Hopkins by the late Sir William Osler almost a century ago has now been discovered by a team of his professional descendants.

Released: 1-Apr-1998 12:00 AM EST
Molecular Switch in Prostate Cancer May Yield Road Map of Cancer Machinery and Targets for Drugs
Texas A&M Health Science Center

Molecular biologists from Texas A&M's Institute of Biosciences and Technology and from Duke University may have found a genetic switch in prostate cancer cells that can change a quiet tumor into an invasive, deadly cancer that spreads throughout the body.

1-Apr-1998 12:00 AM EST
ACP releases fourth edition of Ethics Manual
American College of Physicians (ACP)

The American College of Physicians (ACP) today published the fourth edition of its Ethics Manual. The ACP Ethics Manual appears in the April 1, 1998, issue of Annals of Internal Medicine, published by ACP.

1-Apr-1998 12:00 AM EST
Annals of Internal Medicine TipSheet from the American College of Physicians
American College of Physicians (ACP)

1) Ticlopidine linked with rare blood disease, thrombotic thrombocytopenic purpura (TTP). 2) Internal medicine experts explore the physician-assisted suicide debate. 3) Annals editor concludes two-part series on medicine and commerce. 4) ACP issues fourth edition of ethics manual. (see separate release)

1-Apr-1998 12:00 AM EST
Echocardiography Is Effective In Measuring Microvascular Damage From Heart Attacks
Johns Hopkins Medicine

Ultrasound waves may be as effective as magnetic resonance imaging at detecting small blood vessel blockage after a heart attack, according to researchers at Johns Hopkins.

Released: 31-Mar-1998 12:00 AM EST
When Genes Go Bad: Scientist Uses Drug Combination to Suppress Mutant P53 Gene
Washington State University

Patients with mutant p53 become resistant to treatment. In fact, the proliferating cells can develop other mutations and become more and more resistant. Sayed Daoud's approach is to focus on the p53 gene itself by using a combination of drugs, one to attack the tumor itself and one to inhibit the effect of the mutated p53. When the effect of the mutated p53 is inhibited, the cell usually will, as Daoud puts it, "crash and die."

Released: 31-Mar-1998 12:00 AM EST
Link Made Between Human Growth Hormone, Bone Quality In Mice
University of Michigan

Laboratory mice which have been genetically altered to produce human growth hormone grow to be 25-30 percent larger than normal mice---with much of that size difference coming from bigger bones, according to researchers.

Released: 31-Mar-1998 12:00 AM EST
American College of Physicians' Annual Session April 2 to 5, 1998
American College of Physicians (ACP)

5,000 doctors of internal medicine (internists) will attend the American College of Physicians' (ACP) 1998 Annual Session, the nation's largest gathering of adult health specialists. Faculty are internal medicine's best and brightest. Full complement of experts in end of life care.

31-Mar-1998 12:00 AM EST
Temple Researchers Expand the Number of Heart Transplant Donors
Temple University Health System

Findings of a multi-year heart transplantation study indicate that the heart donor pool can be expanded through the use of undersized hearts. The donor pool for heart transplants could be increased by at least 25%. The use of undersized donor hearts can help to alleviate a shortage of donor organs and save lives.

31-Mar-1998 12:00 AM EST
Aspirin Substitute May Cause Potentially Fatal Platelet Disorder
Northwestern University

Ticlopidine, a drug that acts like aspirin and is widely used to prevent stroke as well as blood clot formation following placement of cardiac stents, can cause thrombotic thrombocytopenic purpura, a rare but potentially deadly circulatory disease.

31-Mar-1998 12:00 AM EST
Motivating muscles: New UD study might help people with paralysis 'stay strong longer'
University of Delaware

People who have suffered paralyzing injuries sometimes can regain limited control of their muscles, thanks to electrical stimulation techniques now under development, but pulse patterns should be varied to help patients stay strong longer, University of Delaware researchers report in the new Journal of Neurophysiology.

31-Mar-1998 12:00 AM EST
Pitt Researchers Find Way to Block Cellular Growth Pathways and Inhibit Tumor Growth
University of Pittsburgh Medical Center (UPMC)

At the annual American Association of Cancer Research meeting in New Orleans, University of Pittsburgh Cancer Institute researchers are presenting exciting evidence from animal models that blocking two cellular growth pathways causes tumor cells to die.

31-Mar-1998 12:00 AM EST
Women Who Smoke While Pregnant Pass Along Genetic Mutations to Their Babies, According to Pitt Researchers
University of Pittsburgh Medical Center (UPMC)

Certain mothers who smoke while pregnant are at high risk of passing along genetic damage to their babies, according to study results presented by University of Pittsburgh scientists on Tuesday, March 31, at the annual American Association for Cancer Research meeting in New Orleans.

31-Mar-1998 12:00 AM EST
Pitt Researchers Find Marker for Bladder Cancer
University of Pittsburgh Medical Center (UPMC)

University of Pittsburgh Cancer Institute researchers are reporting at the annual American Association for Cancer Research meeting in New Orleans that they have found the first specific marker that distinguishes tissues from individuals with bladder cancer from those without disease and that can be easily isolated from urine.

30-Mar-1998 12:00 AM EST
Volumetrics Medical Imaging Inc. Unveils First Commercial Real-Time Volumetric Ultrasound System
Volumetrics Medical Imaging

The first fundamental breakthrough in diagnostic ultrasound in more than a decade was introduced today at the annual meeting of the American College of Cardiology in Atlanta. The Model 1, real-time volumetric ultrasound imaging system, developed by Volumetrics Medical Imaging, Inc. of Durham, N.C., provides instantaneous, quantifiable ultrasound scans of a whole organ, rather than a single slice.

30-Mar-1998 12:00 AM EST
Heart Failure Study Shows High Doses of Ace Inhibitor Zestril (Lisinopril) Provide Significant Therapeutic Benefits
AstraZeneca

For the five million Americans who suffer from congestive heart failure, a new study shows that patients taking high doses of the angiotensin converting enzyme (ACE) inhibitor Zwstril (lisinopril) may live longer and be hospitalized less often than those on low dose therapy. The results were announced today at the 47th Annual American College of Cardiology (ACC) Scientific Session.

30-Mar-1998 12:00 AM EST
New Test Opens Window on Corrosive Free-Radical Activity in Individuals
Perelman School of Medicine at the University of Pennsylvania

Do antioxidant vitamins protect healthy people from free-radical damage? Can some diseases be slowed or reversed with antioxidants? Perhaps surprisingly, no measurement technique has existed to easily and directly assess the corrosive effects in individuals of these highly reactive types of oxygen. Now, scientists have developed such a test.

26-Mar-1998 12:00 AM EST
Natural Sugar-Phosphate Compound Shows Promise as Cancer Treatment; University of Maryland Researcher Halts Growth, Shrinks Liver Tumors
University of Maryland, Baltimore

What if a common, naturally occurring substance could shrink tumors, stop their growth, even make cancer cells normal again? A University of Maryland researcher is finding that it can.

30-Mar-1998 12:00 AM EST
Gene therapy findings updated: Treatment used in patients with blocked leg vessels
American Heart Association (AHA)

DALLAS, March 31 -- A gene therapy approach to circumvent leg blood vessels obstructed by atherosclerosis that was reported last fall at the American Heart Association's Scientific Sessions has been successfully extended to a larger group of patients.

30-Mar-1998 12:00 AM EST
New Pathway Offers Hope for Anti-Cancer Agents
Temple University Health System

Two separate pathways are now associated with the growth of human tumors. The Src-STAT-3 pathway plays a critical role in the proliferation of human breast, prostate, ovarian and lung cancer cells. This discovery will offer researchers a target for the development of new diagnostic tests and anti-cancer agents.

Released: 28-Mar-1998 12:00 AM EST
Subject to Intense Scientific Scrutiny, Emotions Appear More Important Than Ever
University of Wisconsin-Madison Department of Medicine

Scientists from around the world will gather at the University of Wisconsin, April 17-18, to discuss their latest findings demonstrating the biological underpinnings of emotion, and the profound effects positive and negative feelings can have on human health. The latest technological advances used to identify brain systems associated with different emotions will also be described.

Released: 28-Mar-1998 12:00 AM EST
Recent School Violence Is Wake-Up Call for the Nation
Mental Health America

"The Arkansas schoolyard shooting and other recent acts of school violence are a wake-up call to the nation about our children," said Michael Faenza, President and CEO of the National Mental Health Association.

Released: 28-Mar-1998 12:00 AM EST
Mental Health Parity Would be Boon to Millions of Americans with Mental and Substance Abuse Disorders
Mental Health America

"Full parity is cheap and good public policy precisely because behavioral health treatments work. Treatment restores functioning at home, work and school, reducing other social costs by improving lives," said Michael Faenza, President and CEO of the National Mental Health Association.

Released: 27-Mar-1998 12:00 AM EST
Study shows hypertension in African Americans can be prevented
Vanderbilt University

African Americans are not necessarily genetically predisposed to hypertension, according to a study by a team of researchers from Meharry Medical College and Vanderbilt University that has discovered that hypertension, obesity and high cholesterol in African Americans can be prevented with a radical change in lifestyle.

Released: 27-Mar-1998 12:00 AM EST
Four-year Study Shows Calcium Supplements Reduce Bone Loss, Help Prevent Osteoporosis
Mayo Clinic

Calcium supplements reduce bone loss in elderly women, although only modestly, and can help prevent osteoporosis in women who don't already have the condition, reports a Mayo Clinic study.

Released: 27-Mar-1998 12:00 AM EST
New Resource For Treating Women's Medical Emergencies
University of Michigan

First care providers can now have the latest knowledge from top medical experts in the field of emergency medicine, obstetrics and gynecology at their fingertips. The book will help family physicians, as well as emergency medicine doctors, quickly and effectively diagnose and treat emergency gynecologic and obstetric problems.

Released: 27-Mar-1998 12:00 AM EST
Media Briefing -- Ultrasound Breakthrough Allows Instant 3D Scans of Heart
Volumetrics Medical Imaging

The co-founders of Volumetric Medical Imaging, Inc. will conduct a media briefing to demonstrate Volumetric Sonography (tm) "” the first fundamental breakthrough in diagnostic ultrasound in more than decade.

Released: 27-Mar-1998 12:00 AM EST
UCLA Medical Center Saves Patient with Revolutionary Heart-Assist Device
University of California, Los Angeles (UCLA), Health Sciences

A temporary heart device used by cardiac doctors at UCLA Medical Center saved a 24-year-old patient dying from heart failure. The cardiac-assist device avoided the need for an emergency heart transplant.

Released: 27-Mar-1998 12:00 AM EST
Experimental Treatment at UCLA Attempts to Combat Recurrent Benign Brain Tumors with Chemotherapy
University of California, Los Angeles (UCLA), Health Sciences

Benign, non-cancerous brain tumors, called meningiomas, can impair brain function and even kill. So UCLA medical researchers have begun testing a new form of chemotherapy to treat them.

Released: 27-Mar-1998 12:00 AM EST
No sweat! Positive thoughts help exercisers stick with it
Washington University in St. Louis

Although researchers know that half of all folks who take up exercise quit during the first six months, they have failed to ask how peopleís thoughts and feelings during workouts affect their decision to drop out.

Released: 27-Mar-1998 12:00 AM EST
Needlestick Injuries Common in Female Veterinarians
Ohio State University

Two out of every three female veterinarians have reported accidental needlestick wounds while they were on the job, according to a recent study.

Released: 27-Mar-1998 12:00 AM EST
Program Shows Promise for Treating Children with Mood Disorders
Ohio State University

Researchers at Ohio State University have developed a new intervention program that shows early signs of helping children and teenagers with mood disorders.

Released: 27-Mar-1998 12:00 AM EST
Troubled Teens Report Serious Problems with Marijuana Dependence
University of Colorado Anschutz Medical Campus

A University of Colorado study of marijuana dependence among adolescents in a university treatment program found that such youth reported serious problems in their lives related to dependence on the drug.

Released: 27-Mar-1998 12:00 AM EST
Two Simple Tests May Screen For Carpal Tunnel Syndrome
Ohio State University

Based on a new study, researchers are suggesting physicians use two simple tests to screen patients for carpal tunnel syndrome (CTS).

Released: 27-Mar-1998 12:00 AM EST
Prostate Cancer Treatment From U of Minnesota Works in Mice; Researchers Aim for Clinical Trials in Fall
University of Minnesota

A prostate cancer treatment that kills cancer cells while largely sparing healthy organs has been successfully tested in mice and will be ready for clinical trials this fall if approved by the Food and Drug Administration, according to University of Minnesota researchers who devised the treatment.

Released: 27-Mar-1998 12:00 AM EST
Primary Care Doctors Enlisted to help fight Debilitating Sleep Disorders
Stanford Medicine

Until every primary care physician in the United States recognizes and responds to the signs of life-depleting and sometimes fatal sleep disorders, Dr. William C. Dement believes his work is unfinished.

Released: 27-Mar-1998 12:00 AM EST
Hard Hearts: New Discovery of Bone in Heart Tissue May Explain Valve Disease
Perelman School of Medicine at the University of Pennsylvania

For the first time, researchers at the University of Pennsylvania Medical Center have confirmed that bone--similar to that found in the human skeleton--is present in a substantial portion of diseased heart valves.This finding could lead to the development of therapies to prevent or treat heart-valve disease.

Released: 26-Mar-1998 12:00 AM EST
Phamacist Attracts National Media Interest in Herbal Medicine Study
University of Arkansas for Medical Sciences

Bill J. Gurley, Ph.D., associate professor and chairman of the Department of Pharmaceutics in the UAMS College of Pharmacy's recent study of herbal medicines containing ephedrine has attracted media attention. Supplements containing ephedrine are widely used, especially by students to help them stay awake to study. The danger is that too much ephedrine can cause adverse side effects and even death.



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