Case Western Reserve University chemical engineer Rohan Akolkar is leading a research team working to develop a new zero-carbon, electrochemical process to produce iron metal from ore. If successful, the project could be a first step toward eliminating harmful greenhouse gas emissions by eventually replacing century-old, blast-furnace ironmaking with a new electrolytic-iron production process.
U.S. military veterans who lived in what were once known as “redlined” areas had a higher risk for heart attacks and other cardiovascular issues, according to a new study by researchers at Case Western Reserve University, University Hospitals and the Cleveland VA Medical Center.
Electrochemical engineer Rohan Akolkar from Case Western Reserve University in Cleveland, Ohio—whose pioneering research has applications in nano-material fabrication, energy storage, electrometallurgy and sensors—has been selected as the 2023 winner of an international award from The Electrochemical Society (ECS).
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The city’s recreation centers offer opportunities from cooking classes to robotics workshops. But Case Western Reserve University researchers found—through partnership and exhaustive examination—these community hubs serve another critical function: as safe spaces where children often vulnerable to trauma can heal.
Irregularities in the body’s genetic coding to make proteins are linked to cancerous tumors. But most genetic material contains elements whose function isn’t clear. Could abnormalities in non-coding material also impact a person’s health, or even be linked to cancers as well? A new study by researchers at the Case Western Reserve University School of Medicine suggests that the non-coding genetic molecules also play a key role in health and disease, including tumor development.
A regional collaboration led by Case Western Reserve University has won a $1 million grant from the National Science Foundation (NSF) --the only award in Ohio--to plan economic, environmental and manufacturing growth across the 18-county Northeast Ohio region.
Food insecurity—the lack of steady access to nutritionally adequate food—during pregnancy is linked to premature births and poorer health for low-income mothers and their babies, contributing to staggering rates of infant mortality in Cleveland and Cuyahoga County. To address this critical need, a partnership between the Case Western Reserve University School of Medicine (CWRU), Greater Cleveland Food Bank (GCFB) and Better Health Partnership’s Community Pathways HUB (HUB) created a pilot program called Nourishing Beginnings (NB). The program was launched in 2022 with funding from the Vitamix and Bruening foundations and CWRU’s Clinical and Translational Science Collaborative.
Researchers from Case Western Reserve University and University Hospitals Cleveland Medical Center (UH) have secured $6.2 million from two grants awarded in the same month from the National Institutes of Health (NIH) to predict cardiovascular disease through new artificial intelligence (AI) approaches.
Brian McDermott, a Case Western Reserve scientist, is reporting a discovery about unexpected asymmetry on the hair cells of zebrafish that allow them to detect movement with greater sensitivity from the back than the front. “This shows that fish have hair cells that are actually tuned to sense different water directions,” McDermott said. “In humans, our cochleas have hair cells that are similarly tuned to be able to hear different frequencies.” McDermott said the finding also advances our understanding of “the long-sought mechanotransduction (Mec) channel” in living creatures.
Case Western Reserve University law professor examines legal grey area when semi-autonomous vehicles are involved in accidents
Beyond vaccines, mRNA offers immense potential to fight disease, but targeting the genetic material to specific diseased cells is challenging—requiring a new method. To meet this need, researchers at the Case Western Reserve University School of Medicine, with a Global Research Fellowship award from Moderna Inc., are developing a process that essentially uses bubbles to overcome the problem.
With a new three-year, $2.56 million grant from The John A. Hartford Foundation, the Frances Payne Bolton School of Nursing at Case Western Reserve University will evaluate improvements in care, economic impact and equity in outcomes of 1.2 million older adults receiving “age-friendly” care at MinuteClinics nationally.
Case Western Reserve University (CWRU) has completed an exclusive license agreement with Atlanta-based RORA Biologics Inc. (RORA-Bio) for intellectual property to develop new therapies to treat HIV and certain kinds of cancer.
As cocaine use continues to climb across the United States, scientists have struggled to develop an effective pharmacological approach to treat the devastating disorder. But by seamlessly combining artificial intelligence (AI), human intelligence, clinical testing and computer analysis, researchers at Case Western Reserve University have unearthed an existing option that appears to hold promise.
The Inamori International Center for Ethics and Excellence at Case Western Reserve University will award Myroslava Gongadze, a journalist and free-press and human-rights advocate, with the 2023 Inamori Ethics Prize.
With a new five-year, $3.03 million grant from the National Cancer Institute—an agency of the National Institutes of Health—Case Western Reserve University researchers are leading the development and commercialization of a novel MRI and software technology that results in more accurate, consistent brain tumor diagnosis.
PERI, at the Begun Center for Violence Prevention and Research at Case Western Reserve University’s Jack, Joseph and Morton Mandel School of Applied Social Sciences, offers evaluation services and support to local nonprofits.
Case Western Reserve University researchers found that the impacts of 1930s lending practices persist today across the state of Ohio.
Case Western Reserve University (CWRU) developed the HoloAnatomy® Software Suite to teach human anatomy in a more intuitive, cost-effective way using holographic imagery. Building on its long history of bringing influential research into the public domain, CWRU has announced the launch of Ilumis, Inc. to accelerate product innovation, improve partner service, and rapidly scale the potential of this revolutionary learning platform.
With a new $3 million-plus grant from the National Institutes of Health (NIH), Case Western Reserve University researchers are examining the next level of treatment for Candida auris (C.auris), a multidrug-resistant yeast that causes serious infection and, in some cases, death.
The National Institutes of Health (NIH) has awarded the Case Western Reserve University (CWRU) School of Medicine a five-year, $7.3 million grant to identify new technology, methods and models to study the impact of inflammation and pain on eye health, specifically the surface.
Case Western Reserve University researchers have identified a mechanism in brain tissue that may explain why women are more vulnerable to Alzheimer’s disease—a finding that they say could help lead to new medicines to treat the disease. The researchers found that the female brain shows higher expression of a certain enzyme compared to males, resulting in greater accumulation of a protein called tau.
The National Institutes of Health (NIH) has awarded a $15.75 million contract to researchers led by Case Western Reserve and Duke universities to accelerate development of therapeutic devices that improve chronic medical conditions.
Stress has been linked to all sorts of serious health issues, from insomnia to high blood pressure, obesity and even heart disease. But it’s generally acknowledged that some stress can also be helpful, like when someone’s chasing a work deadline. But what if some level of stress can actually protect the body? A new study by researchers at the Case Western Reserve University School of Medicine, with findings published Sept. 26 in Proceedings of the National Academy of Sciences, suggests the immune system may benefit from a measure of stress.
Case Western Reserve University has received a $14.2 million grant from the U.S. Department of Energy’s National Nuclear Security Administration (NNSA) to launch a “Center of Excellence” focused on applying innovative approaches to enhancing manufacturing of materials with greater strength and longer lifecycles.
Children who were infected with COVID-19 show a substantially higher risk of developing type 1 diabetes (T1D), according to a new study that analyzed electronic health records of more than 1 million patients ages 18 and younger.
The National Prion Disease Pathology Surveillance Center (NPDPSC) at Case Western Reserve University will receive up to $20 million in funding as part of a grant renewal from the Centers for Disease Control and Prevention (CDC) to better understand how and why prion diseases––degenerative brain conditions found in both humans and animals—develop and spread.
Gay men are more than twice as likely to develop inflammatory bowel disease (IBD) than heterosexual men when both populations engage in high-risk sexual activity, according to new research from the Digestive Health Research Institute at Case Western Reserve University and University Hospitals Cleveland Medical Center (UH).
Older people who were infected with COVID-19 show a substantially higher risk—as much as 50% to 80% higher than a control group—of developing Alzheimer’s disease within a year, according to a study of more than 6 million patients 65 and older.
In a new study, researchers from the Case Western Reserve University School of Medicine have identified the structure of protein fibrils linked to a hereditary form of human prion disease. This insight, they say, reveals the mechanism for how prions can jump between some animal species, while retaining a transmissibility barrier between other species.
Case Western Reserve University in Cleveland, Ohio, ranks No. 21 globally for the number of U.S. Utility Patents awarded to the university and its researchers, according to 2021 data compiled by the U.S. Patent and Trademark Office (USPTO).
Research led by Case Western Reserve University has identified a promising path to developing therapies to treat esophageal tumors––a form of cancer that not only is among the most deadly, but also has been occurring at increasing rates over the past decade.
The research arm of the U. S. Army has awarded Case Western Reserve University blood surrogate pioneer Anirban Sen Gupta a four-year, $2.5 million grant to advance and optimize his latest nanotechnology to stop bleeding from battlefield injuries. The new technology devised by Sen Gupta and his team is called “SanguiStop.” It allows a clot-promoting enzyme called thrombin to be intravenously delivered in a targeted manner to a bleeding area—especially to the site of internal injuries.
Older physicians benefit from their many years of experience and the skills they have developed over decades of practice. At the same time, they may be at risk of cognitive decline, raising concerns about job performance deficits.
Leading researchers will gather this week at a Case Western Reserve University-led symposium highlighting progress and opportunities in biomedical research and human-performance sciences. The event takes place this Thursday and Friday, Aug. 18-19, at the Wolstein Research Center on the Case Western Reserve campus, and features researchers and clinicians from the university, area hospital affiliates and the Wright-Patterson Air Force Base in Dayton.
The new five-year, $500,000 grant will support Ayday’s ongoing work to identify, analyze and mitigate privacy vulnerabilities for individuals who share their genomic information with institutions, which then share the data with wider genomic databases. Personal genomic data refers to each person’s unique genome, his or her genetic makeup and information that can be gleaned from DNA analysis of a blood test or saliva sample.
A team of researchers at the Case Western Reserve University School of Medicine and Case Comprehensive Cancer Center believe they have identified a cell signaling pathway responsible for the development of esophageal adenocarcinomas, an aggressive form of esophageal cancer that has gradually become more common, even in younger people.
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