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Delivery of Stem Cell Secretome for Therapeutic Applications F Li, J Zhang, K Yi, H Wang, H Wei, HF Chan, Y Tao… - ACS Applied Bio Materials, 2022 … delivery of stem cell secretome deserve more attention. In this review, we first discuss approaches for the production and characterization of stem cell secretome and their optimization strategies. Moreover, the up-to-date studies to improve the … [HTML] Cancer Stem Cell Markers for Urinary Carcinoma P Xia, DH Liu, ZJ Xu, F Ren - Stem Cells International, 2022 … Cancer stem cell (CSC) refers to cancer cells with stem cell properties, that is, they have the ability of “self-renewal” and “differentiation.” … In this review, cancer stem cell surface markers and functional markers in urinary system were summarized …

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… In contrast, incidence of postprocedural stroke was relatively low in our study (1.8%), and periprocedural AF was not associated with higher risk of stroke. Risk of stroke after TAVR can be affected by various factors, including antithrombotic regimens …

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… remain high when compared to other TAVR related complications. We assessed outcomes in consecutive patients treated with TAVR using a novel Tri-… Non disabling stroke was observed in 1 patient. Median discharge was 1 day post TAVI …

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… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

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… and use of OAC in patients with TAVR and AF, we excluded all patients with a prior mechanical valve, prior stroke within 1 year, in‐… In an analysis from a large clinical data registry of US patients with AF undergoing TAVR, we found that the 1‐year …

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… Therefore, we sought to assess the association between CEP and stroke-related mortality following TAVR using a large-scale US … mortality risk of stroke following TAVR. This result needs cautious interpretation because the sample size of stroke …

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… In contrast, incidence of postprocedural stroke was relatively low in our study (1.8%), and periprocedural AF was not associated with higher risk of stroke. Risk of stroke after TAVR can be affected by various factors, including antithrombotic regimens …

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… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

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… Post-TAVR stroke causes acute and long-term morbidity and mortality. The stroke rate 30 days after TAVR was reported as 3.4% in low-risk … TAVR may reduce the incidence of ischemic stroke and in-hospital mortality.However, the effectiveness of …

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… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

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… In contrast, incidence of postprocedural stroke was relatively low in our study (1.8%), and periprocedural AF was not associated with higher risk of stroke. Risk of stroke after TAVR can be affected by various factors, including antithrombotic regimens …

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… protein C receptor (EPCRhigh) were enriched within the stem cell fraction at the expense of more proliferative EPCRLow HSCs. These … stem cell function. We herein attempted to elucidate the mechanisms by which HSCs convert the effects of …

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… Reports show that > 95% of endovascular TAVR in the US is via transfemoral access, so our population are mostly patients undergoing … in non-TAVR populations [28]. Our study shows that the procedure-related stroke rate was not …

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NK cell content does not seem to influence engraftment in ex vivo T cell depleted haploidentical stem cell tra … usefulness of NK cellderived IFNg inhibition to favor engraftment in allogeneic hematopoietic stem cell transplantation (HSCT) …

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… Post-TAVR stroke causes acute and long-term morbidity and mortality. The stroke rate 30 days after TAVR was reported as 3.4% in low-risk … TAVR may reduce the incidence of ischemic stroke and in-hospital mortality.However, the effectiveness of …

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… In addition, MSCs derived from different donors and tissues lead to individual heterogeneity, which complicates the progress of consistent and standardized stem cell production. Therefore, it is necessary to screen qualified MSCs to avoid uncertain effects. …

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… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

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… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

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… stem cell niches, whose repairing ability is not able to overcome severe damage (heart or nervous tissue). The purpose of this review is to … the main characteristics of stem cell niches in these different tissues, highlighting the various components …

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… primary endpoint of death or disabling stroke were 4.3% in the TAVR group and 6.3% in the … between years 1 and 2 as it relates to early TAVR benefits seen in death or disabling stroke. … used Bayesian statistical inference to predict that TAVR …

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… In contrast, incidence of postprocedural stroke was relatively low in our study (1.8%), and periprocedural AF was not associated with higher risk of stroke. Risk of stroke after TAVR can be affected by various factors, including antithrombotic regimens …

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… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

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… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

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… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

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… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

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… and use of OAC in patients with TAVR and AF, we excluded all patients with a prior mechanical valve, prior stroke within 1 year, in‐… In an analysis from a large clinical data registry of US patients with AF undergoing TAVR, we found that the 1‐year …

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… Our meta‐analysis suggests that in post‐TAVR patients requiring OAC therapy, all‐cause mortality, stroke or systemic embolism, and major and/or life‐threatening bleeding are similar between the NOAC and VKA groups. The NOACs may be considered as …

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… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

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… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

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… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

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… The mechanisms underlying operational tolerance after hematopoietic stem cell transplantation in humans are poorly understood. We studied two independent cohorts of patients who underwent allogeneic hematopoietic stem cell …

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… It then describes our current understanding of the biological mechanisms that govern the stem cell response to surface topographies and highlights specific impacts on stem cell fate. Finally, we consider the translational implications and …

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… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

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… TAVR in patients with another indication of OAC, which were published before 28th September 28, 2021. The effectiveness of outcomes was all-cause mortality and stroke … We included 4947 post-TAVR patients with another indication of OAC …

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… Stem cell–derived insulin-producing cells can theoretically be generated in endless quantities… stem cell–based therapies for type 1 diabetes. The approaches are very different. Vertex embarked on a phase I/II clinical trial in March 2021 in …

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… Background: Stroke associated with transcatheter aortic valve replacement (TAVR) is a potentially devastating complication. Until recently, … of TAVR-related stroke. However, its effectiveness is still undetermined. Objectives: To explore the impact of …

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… A meta-analysis including 7673 patients undergone to TAVR demonstrated that low stroke-volume index, a parameter of transaortic flow, was related with an increased mortality compared with patients with normal stroke volume index [36] …

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… A meta-analysis including 7673 patients undergone to TAVR demonstrated that low stroke-volume index, a parameter of transaortic flow, was related with an increased mortality compared with patients with normal stroke volume index [36] …

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… As compared to patients with a large PA/BSA, the occurrence of a stroke at 30 days was higher in patients with a small PA/BSA in the present cohort. The risk for stroke after TAVR is likely to be multifactorial [33]. Seppelt et al. reported that balloon-expandable …

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… through the regulation of p27Kip1 mRNA translation and modulates glioma stem cell differentiation via regulating Hes1 and Sirt1 translation 36,… may be a potential Aurka downstream target, regulating SC function with regards to stem cell self-renewal …

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… As compared to patients with a large PA/BSA, the occurrence of a stroke at 30 days was higher in patients with a small PA/BSA in the present cohort. The risk for stroke after TAVR is likely to be multifactorial [33]. Seppelt et al. reported that balloon-expandable …

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Few approaches have been made toward exploring autologous NK cells in settings of cancer immunotherapy. Here, we demonstrate the feasibility of infusing multiple doses of ex vivo activated and expanded autologous NK cells in patients with …