Trusted by:

clients clients clients clients clients clients clients clients clients clients
10-Jun-2011 9:00 AM EDT
Aurora A May Contribute to Kidney Disease
The Rockefeller University Press

The Aurora A kinase may contribute to polycystic kidney disease (PKD) by inactivating a key calcium channel in kidney cells, according to a study in the June 13 issue of The Journal of Cell Biology.

10-Jun-2011 9:00 AM EDT
Decoding Chronic Lymphocytic Leukemia
The Rockefeller University Press

A paper published online on June 13 in the Journal of Experimental Medicine identifies new gene mutations in patients with chronic lymphocytic leukemia (CLL)—a disease often associated with lack of response to chemotherapy and poor overall survival.

7-Jul-2011 4:35 PM EDT
SUMO Defeats Protein Aggregates That Typify Parkinson’s Disease
The Rockefeller University Press

A small protein called SUMO might prevent the protein aggregations that typify Parkinson’s disease (PD), according to a new study in the July 11, 2011, issue of The Journal of Cell Biology.

14-Jul-2011 4:00 PM EDT
AMPK Amplifies Huntington’s Disease
The Rockefeller University Press

A new study describes how hyperactivation of AMP-activated protein kinase (AMPK) promotes neurodegeneration in Huntington’s disease (HD). The article appears online on July 18, 2011, in The Journal of Cell Biology.

27-Jul-2011 3:00 PM EDT
Key Growth Factor Identified in T Cell Leukemia
The Rockefeller University Press

Blocking a growth factor receptor cripples cancer growth in a form of T cell leukemia, according to a study published online on August 1 in the Journal of Experimental Medicine (www.jem.org).

14-Sep-2011 3:40 PM EDT
Tumor Environment Keeps Tumor-Fighting T Cells Away
The Rockefeller University Press

Tumors have an arsenal of tricks to help them sidestep the immune system. A study published on September 19 in the Journal of Experimental Medicine reveals a new trick—the ability to keep tumor-fighting T cells out by disabling a T cell–attracting protein within the tumor core.

27-Sep-2011 3:10 PM EDT
Bacteria Enter Via Mucus-Making Gut Cells
The Rockefeller University Press

Cells making slippery mucus provide a sticking point for disease-causing bacteria in the gut, according to a study published on October 3 in the Journal of Experimental Medicine.

7-Oct-2011 2:50 PM EDT
Good Housekeeping Maintains a Healthy Liver
The Rockefeller University Press

Differences in the levels of two key metabolic enzymes may explain why some people are more susceptible to liver damage, according to a study in the October 17 issue of The Journal of Cell Biology (www.jcb.org).

19-Oct-2011 11:25 AM EDT
Study Shows Alzheimer’s Disease–Related Peptides Form Toxic Calcium Channels in the Plasma Membrane
The Rockefeller University Press

The neurodegeneration associated with Alzheimer's disease is thought to be caused by small, soluble A-beta complexes, partly through their ability to induce excess calcium influx into cells, which stimulates cell death. A new study reveals that A-beta oligomers elevate calcium by forming calcium-permeable pores in the plasma membrane.

9-Nov-2011 1:55 PM EST
Potential New Drug Target in Lou Gehrig’s Disease
The Rockefeller University Press

Two proteins conspire to promote Lou Gehrig’s disease, according to a study published in the Journal of Experimental Medicine.


close
2.25531