Improved Fluorescence Methods for High-Throughput Protein Formulation Screening
A study demonstrates the feasibility of using a steady-state/lifetime fluorescence plate reader for direct optimization of challenging formulation conditions and highlights the importance of performing formulation optimization under commercially...
28-Nov-2018 5:05 AM EST
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Is Targeting the Inflammasome a Way Forward for Neuroscience Drug Discovery?
Researchers from the University of Manchester explore recent developments and strategies for targeting the NLRP3 inflammasome as a potential therapeutic target in acute and chronic neurological and neurodegenerative diseases, and offer perspective...
26-Nov-2018 3:05 PM EST
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Harnessing Artificial Intelligence to Improve Drug Combination Design and Personalized Medicine
A new auto-commentary looks at how an emerging area of artificial intelligence, specifically the analysis of small systems-of-interest specific datasets, can be used to improve drug development and personalized medicine.
21-Sep-2018 5:05 AM EDT
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Advancing Life Sciences Research with the Internet of Things
The internet of things (IoT) is allowing scientists to optimize laboratory operations and combine instruments to measure and respond to complex experimental conditions. As a result, IoT is enabling more detailed and more complex experimental...
17-Sep-2018 3:05 PM EDT
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Screening Strategies and Methods for Better Off-Target Liability Prediction and Identification of Small-Molecule Pharmaceuticals
A new review explores how improved safety screening strategies and methods are improving the pharmaceutical discovery and development process. The authors outline several fundamental methods of the current drug screening processes and emerging...
6-Sep-2018 5:05 AM EDT
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High-Throughput Flow Cytometry in Drug Discovery
A new special issue of SLAS Discovery reflects examples of the recent groundswell of creative new applications for high-throughput flow cytometry (HTFC) in drug discovery.
24-Jul-2018 6:05 AM EDT
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Enabling Technology in Cell-Based Therapies: Scale-Up, Scale-Out or Program In-Place
Technologies that are reducing costs and changing the ways in which researchers and clinicians process and use therapeutic cells are showcased in the August 2018 special issue of SLAS Technology.
23-Jul-2018 11:05 AM EDT
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Platforms for Investigating LncRNA Functions
To aid in the discovery and understanding of lncRNA biology, newly published work features the technological platforms and methodology presently used to identify the roles of lncRNA in biology. This work highlights the databases and tools used to...
25-Jun-2018 7:05 AM EDT
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