Screening Strategies and Methods for Better Off-Target Liability Prediction and Identification of Small-Molecule Pharmaceuticals
A new review explores how improved safety screening strategies and methods are improving the pharmaceutical discovery and development process. The authors outline several fundamental methods of the current drug screening processes and emerging...
6-Sep-2018 5:05 AM EDT
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High-Throughput Flow Cytometry in Drug Discovery
A new special issue of SLAS Discovery reflects examples of the recent groundswell of creative new applications for high-throughput flow cytometry (HTFC) in drug discovery.
24-Jul-2018 6:05 AM EDT
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Enabling Technology in Cell-Based Therapies: Scale-Up, Scale-Out or Program In-Place
Technologies that are reducing costs and changing the ways in which researchers and clinicians process and use therapeutic cells are showcased in the August 2018 special issue of SLAS Technology.
23-Jul-2018 11:05 AM EDT
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Platforms for Investigating LncRNA Functions
To aid in the discovery and understanding of lncRNA biology, newly published work features the technological platforms and methodology presently used to identify the roles of lncRNA in biology. This work highlights the databases and tools used to...
25-Jun-2018 7:05 AM EDT
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Using Fragment-Based Approaches to Discover New Antibiotics
A new SLAS Discovery review article summarizes new methods of fragment-based lead discovery (FBLD) to identify new compounds as potential antibiotics. It explains how FBLD works and illustrates its advantages over conventional high-throughput...
18-Jun-2018 9:05 AM EDT
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Integrated Lead Discovery: An Evolving Toolbox
A new SLAS Discovery review article by GlaxoSmithKline researchers in the U.S. and U.K. offers an informative guide to the established and emerging tools available for early drug discovery and screening, and provides illustrative scenarios...
20-Jun-2018 3:05 AM EDT
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Clinical Trials in a Dish: A Perspective on the Coming Revolution in Drug Development
Researchers share perspective about Clinical Trials in a Dish (CTiD), a novel strategy that bridges preclinical testing and clinical trials.
30-May-2018 1:05 AM EDT
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The Evolution in Flow Cytometry: Turning a Low-Throughput Platform into an Automated High-Throughput System
New research highlights a diversity of approaches that an automated high-throughput flow cytometry has enabled for phenotypic drug discovery.
24-May-2018 8:05 AM EDT
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