OCTN: A Small Transporter Subfamily with Great Relevance to Human Pathophysiology, Drug Discovery and Diagnostics
A new review by researchers from the University of Calabria (Italy) explores OCTNs, a small but intriguing group of transporters that are opening new frontiers in drug design research for improving drug delivery and predicting drug-drug...
29-Jan-2019 10:05 AM EST
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Announcing the 2018 SLAS Technology Ten: Translating Life Sciences Innovation
The SLAS Technology Ten annually showcases ten individual articles that stand out as the most innovative scientific achievements published in SLAS Technology in the past 12 months.
24-Jan-2019 10:05 AM EST
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Advances in 3D and Organoid Cell Culture
A new collection of reviews and original research illustrate how new technologies and advanced cell culture are accelerating basic research, drug discovery and drug development.
17-Jan-2019 3:05 AM EST
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Improved Fluorescence Methods for High-Throughput Protein Formulation Screening
A study demonstrates the feasibility of using a steady-state/lifetime fluorescence plate reader for direct optimization of challenging formulation conditions and highlights the importance of performing formulation optimization under commercially...
28-Nov-2018 5:05 AM EST
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Is Targeting the Inflammasome a Way Forward for Neuroscience Drug Discovery?
Researchers from the University of Manchester explore recent developments and strategies for targeting the NLRP3 inflammasome as a potential therapeutic target in acute and chronic neurological and neurodegenerative diseases, and offer perspective...
26-Nov-2018 3:05 PM EST
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Harnessing Artificial Intelligence to Improve Drug Combination Design and Personalized Medicine
A new auto-commentary looks at how an emerging area of artificial intelligence, specifically the analysis of small systems-of-interest specific datasets, can be used to improve drug development and personalized medicine.
21-Sep-2018 5:05 AM EDT
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Advancing Life Sciences Research with the Internet of Things
The internet of things (IoT) is allowing scientists to optimize laboratory operations and combine instruments to measure and respond to complex experimental conditions. As a result, IoT is enabling more detailed and more complex experimental...
17-Sep-2018 3:05 PM EDT
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Screening Strategies and Methods for Better Off-Target Liability Prediction and Identification of Small-Molecule Pharmaceuticals
A new review explores how improved safety screening strategies and methods are improving the pharmaceutical discovery and development process. The authors outline several fundamental methods of the current drug screening processes and emerging...
6-Sep-2018 5:05 AM EDT
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