Feature Channels: Stem Cells

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Released: 16-Aug-2022 12:00 PM EDT
Fludarabine/TBI 8 Gy versus fludarabine/treosulfan conditioning in patients with AML in first complete remission: A Study from the Acute Leukemia Working Party of the EBMT
Preprints

Gesine Bug, Myriam Labopin, Riitta Niittyvuopio, Matthias Stelljes, Christian Reinhardt, Inken Hilgendorf, Nicolaus Kroeger, Ain Kaare, Wolfgang Bethge, Kerstin Schaefer-Eckart, Mareike Verbeek, Stephan Mielke, Kristina Carlson, Ali

Released: 16-Aug-2022 12:00 PM EDT
Collagen Ⅰ-DDR1 signaling promotes hepatocellular carcinoma cell stemness via Hippo signaling repression.
Preprints

Yi-Xiao Xiong, Xiaochao Zhang, Jing-Han Zhu, Yuxin Zhang, Yonglong Pan, Yu Wu, Jian-Ping Zhao, Junjie Liu, Yuan-Xiang Lu, Huifang Liang, Zhanguo Zhang, Wanguang Zhang

Released: 15-Aug-2022 12:00 PM EDT
Directed differentiation of mouse pluripotent stem cells into functional lung-specific mesenchyme
Preprints

The successful generation of endodermal, ectodermal, and most mesodermal lineages from pluripotent stem cells has resulted in basic discoveries and regenerative medicine clinical trials of cell-based therapies.

Released: 15-Aug-2022 12:00 PM EDT
Alcam-a and Pdgfr-α are essential for the development of sclerotome derived stromal cells that support hematopoiesis in vivo.
Preprints

: Mesenchymal stromal cells are essential components of hematopoietic stem and progenitor cell (HSPC) niches, regulating HSPC proliferation and fate decisions.

Released: 15-Aug-2022 12:00 PM EDT
Mechanical force sensing drives extrusion of Enterovirus A71-infected cells from colonic epithelial organoids
Preprints

Jasmine Moshiri, Ailsa Craven, Sara Mixon, Manuel Amieva, Karla Kirkegaard

Released: 15-Aug-2022 12:00 PM EDT
Mesenchymal stem cells transplantation combined with IronQ attenuates ICH-induced inflammation response via Mincle/Syk signaling pathway
Preprints

Guoqiang Yang, Jiraporn Kantapan, Maryam Mazhar, Xue Bai, Yuanxia Zou, Honglian Wang, Bingfeng Huang, Sijing Yang, Nathupakorn Dechsupa, Li Wang

Released: 15-Aug-2022 12:00 PM EDT
Lipids Maintain Genomic Stability and Developmental Potency of Murine Pluripotent Stem Cells
Preprints

Liangwen Zhong, Miriam Gordillo, Xingyi Wang, Yiren Qin, Yuanyuan Huang, Alexey Soshnev, Ritu Kumar, Gouri Nanjangud, Daylon James, C. David Allis, Todd Evans, Bryce Carey, Duancheng Wen

Released: 12-Aug-2022 12:00 PM EDT
Peripherally Inserted Central Venous Catheter for Pediatric Hematologic Diseases; A Retrospective 11-year Single-center Experience.
Preprints

Silvio Ligia, Salvatore Giacomo Morano, Francesca Kaiser, Alessandra Micozzi, Maria Luisa Moleti, Walter Barberi, Fiorina Giona, Antonio Chistolini, Valentina Arena, Alfonso Piciocchi, Maurizio Forgione, Giulia Gasperini, Marco Fabbri, Anna Maria Testi

Released: 12-Aug-2022 12:00 PM EDT
Effect of human breast milk-derived exosomes on the migration and inflammatory response of lipopolysaccharide-exposed dental pulp stem cells
Preprints

Ehsaneh Azaryan, Samira Karbasi, Mansoore Saharkhiz, Mohammad Yahya Hanafi-Bojd, Asghar Zarban, Fariba Emadian Razavi, Mohsen Naseri

Released: 11-Aug-2022 2:45 PM EDT
Large number of stem cell lines carry significant DNA damage, say researchers
University of Cambridge

DNA damage caused by factors such as ultraviolet radiation affect nearly three-quarters of all stem cell lines derived from human skin cells, say Cambridge researchers, who argue that whole genome sequencing is essential for confirming if cell lines are usable.

Released: 11-Aug-2022 12:00 PM EDT
Exercise Training Remodels Adipocyte-Specific Extracellular Matrix Proteins and Alters Innervation and Vascularization in Inguinal White Adipose Tissue (iWAT)
Preprints

Pasquale Nigro, Maria Vamvini, Jiekun Jackie Yang, Tiziana Caputo, Li-Lun Ho, Danae Papadopoulos, Nicholas Philip Carbone, Royce Colin, Jie He, Hirshman Frederick Michael, Joseph Daniel White, Jacques Robidoux, Robert Hickner, Soeren

Released: 11-Aug-2022 12:00 PM EDT
Development of lacrimal gland organoids from iPSC derived multizonal ocular cells
Preprints

Melis Asal, Gamze Koçak, Vedat Sarı, Tuba Reçber, Emirhan Nemutlu, Canan Aslı Utine, Sinan Guven

Released: 11-Aug-2022 12:00 PM EDT
Human model of primary carnitine deficiency cardiomyopathy reveals ferroptosis as a novel disease mechanism
Preprints

Malte Loos, Birgit Klampe, Thomas Schulze, Xiaoke Yin, Konstantinos Theofilatos, Bärbel Ulmer, Carl Schulz, Charlotta Behrens, Tessa Van Bergen, Eleonora Adami, Henrike Maatz, Michaela Schweizer, Susanne Brodesser, Boris Skryabin,

Released: 11-Aug-2022 12:00 PM EDT
Deciphering transcriptional networks during human cardiac development
Preprints

Robin Canac, Bastien Cimarosti, Aurore Girardeau, Virginie Forest, Pierre Olchesqui, Jeremie Poschmann, Richard Redon, Patricia Lemarchand, Nathalie Gaborit, Guillaume Lamirault

Released: 10-Aug-2022 12:00 PM EDT
Severe Combined Immunodeficiency: Improved survival leading to detection of underlying liver disease
Preprints

Anusha Vittal, Nehna Abdul Majeed, Elizabeth Garabedian, Jamie Marko, David E Kleiner, Rob Sokolic, Fabio Candotti, Harry Malech, Theo Heller, Christopher Koh

Released: 10-Aug-2022 12:00 PM EDT
PVT1/miR-136/Sox2/UPF1 axis regulates the malignant phenotypes of endometrial cancer stem cells
Preprints

Qing Li, Fanfei Kong, Rong Cong, Jian Ma, Cuicui Wang, Xiaoxin Ma

Released: 10-Aug-2022 12:00 PM EDT
Human brain organoid model of maternal immune activation identifies radial glia cells as selectively vulnerable
Preprints

Kseniia Sarieva, Theresa Kagermeier, Shokoufeh Khakipoor, Ezgi Atay, Zeynep Yentuer, Katharina Becker, Simone Mayer

Newswise: See-through zebrafish, new imaging method put blood stem cells in high-resolution spotlight
Released: 9-Aug-2022 4:05 PM EDT
See-through zebrafish, new imaging method put blood stem cells in high-resolution spotlight
University of Wisconsin–Madison

MADISON — For the first time, researchers can get a high-resolution view of single blood stem cells thanks to a little help from microscopy and zebrafish.Researchers at the University of Wisconsin–Madison and the University of California San Diego have developed a method for scientists to track a single blood stem cell in a live organism and then describe the ultrastructure, or architecture, of that same cell using electron microscopy.

Released: 9-Aug-2022 12:00 PM EDT
Adipose tissue-derived stromal/stem cells transplantation + cholecalciferol in recent-onset type 1 diabetes patients: twelve months follow up.
Preprints

Joana Rodrigues Dantas, Débora Batista Araújo, Karina Ribeiro Silva, Débora Lopes Souto, Maria De Fátima Carvalho Pereira, RonirRaggio LUIZ, Cesar Claudio-Da-Silva, Carlos Eduardo Barra Couri, Angelo Maiolino, Carmen Lúcia Kuniyoshi Rebelatto, Débora Regina Daga, Alexandra Cristina Senegaglia,

Released: 9-Aug-2022 12:00 PM EDT
Activation of the urotensin-II receptor by anti-COVID-19 drug remdesivir induces cardiomyocyte dysfunction
Preprints

Fan-Yan Wei, Asuka Inoue, Akiko Ogawa, Seiya Ohira, Tatsuya Ikuta, Yuri Kato, Shota Yanagida, Yukina Ishii, Yasunari Kanda, Motohiro Nishida

Released: 9-Aug-2022 12:00 PM EDT
Mir-4699 Promotes the Osteogenic Differentiation of Mesenchymal Stem Cells
Preprints

Vahedeh Hosseini, Mahdi Paryan, Ameneh Koochaki, Henry Manuel Cesaire, Samira Mohammadi-Yeganeh

Released: 9-Aug-2022 12:00 PM EDT
SMPD1 Expression Profile and Mutation Landscape Help Decipher Genotype–Phenotype Association and Precision Diagnosis for Niemann–Pick Disease Types A and B
Preprints

Ruisong Wang, Ziyi Qin, Long Huang, Huiling Luo, Han Peng, Xinyu Zhou, Zhixiang Zhao, Mingyao Liu, Pinhong Yang, Tieliu Shi

Released: 9-Aug-2022 12:00 PM EDT
Hypoxia induces early neurogenesis in human fetal neural stem cells by activating the WNT pathway
Preprints

Devanjan Dey, Vadanya Shrivastava, Diksha Joshi, Chitra Mohinder Singh Singal, Sagar Tyagi, Muzaffer Ahmed Bhat, Paritosh Jaiswal, Jai Bhagwan Sharma, Jayanth Kumar Palanichamy, Subrata Sinha, Pankaj Seth, Sudip Sen

Released: 8-Aug-2022 2:15 PM EDT
New injectable gel offers promise for tough-to-treat brain tumors
University of Wisconsin–Madison

The University of Wisconsin–Madison's Cell-Inspired Personalized Therapeutic (CIPT) Lab has developed a powerful immunity-boosting postoperative treatment that could transform the odds for patients with glioblastoma.

Released: 8-Aug-2022 12:00 PM EDT
Origami-based Zygote structure enables pluripotent shape-transforming deployable structure
Preprints

Yu-Ki Lee, Yue Hao, Zhonghua Xi, Woongbae Kim, Youngmin Park, Kyu-Jin Cho, Jyh-Ming Lien, In-Suk Choi

Released: 7-Aug-2022 12:00 PM EDT
Nuclear m6A Reader YTHDC1 Promotes Muscle Stem Cell Activation/Proliferation by Regulating mRNA Splicing and Nuclear Export
Preprints

Yulong Qiao, Qiang Sun, Xiaona Chen, Di Wang, Ruibao Su, Yuanchao Xue, Hao Sun, Huating Wang

Released: 7-Aug-2022 12:00 PM EDT
Translation of dipeptide repeat proteins in C9ORF72-ALS/FTD through unique and redundant AUG initiation codons
Preprints

Yoshifumi Sonobe, Soojin Lee, Gopinath Krishnan, Yuanzheng Gu, Deborah Y. Kwon, Fen-Biao Gao, Raymond Roos, Paschalis Kratsios

Released: 6-Aug-2022 12:00 PM EDT
Hepatocyte Differentiation From Mouse Liver Ductal Organoids By Transducing Four Liver-Specific Transcription Factors
Preprints

Katsuhiro Tomofuji, Jumpei Kondo, Kunishige Onuma, Koki Oyama, Eiji Miyoshi, Ken Fukumitsu, Takamichi Ishii, Etsuro Hatano, Masahiro Inoue

Released: 6-Aug-2022 12:00 PM EDT
Culture of human nasal olfactory stem cells and their extracellular vesicles as advanced therapy medicinal products
Preprints

Charlotte Jaloux, Maxime Bonnet, Marie Vogtensperger, Marie Witters, Julie Veran, Laurent Giraudo, Florence Sabatier, Justin Michel, Romaric Lacroix, Corinne Chareyre, Regis Legre, Gaelle Guiraudie Capraz, Francois Feron

Released: 5-Aug-2022 12:00 PM EDT
Fibulin2: A negative regulator of BMSC osteogenic differentiation in infected bone fracture healing
Preprints

Xiang Xu, Shidan Li, Wei Xing, Shaochuan Wang, Youbin Li, Hao Jiang, Hanxuan Zheng, XiaoMing Li, Jing Yang, Debin Guo, Xiaoyu Xie, Renqing Jiang, Chao Fan, Lei Li, Jun Fei

Released: 5-Aug-2022 12:00 PM EDT
Methanol fixation is the method of choice for droplet-based single-cell transcriptomics of neural cells
Preprints

Ana Gutierrez-Franco, Mohamed N. Hassan, Loris Mularoni, Mireya Plass

Released: 5-Aug-2022 12:00 PM EDT
Elucidation of adipogenic differentiation regulatory mechanism in human maxillary/mandibular bone marrow-derived stem cells
Preprints

Haruka Miyata, Masakazu Ishii, Fumio Suehiro, Naohiro Komabashiri, Nao Ikeda, Tomoaki Sakurai, Masahiro Nishimura

Released: 5-Aug-2022 12:00 PM EDT
Intra-peritoneal transplantation for efficient and easy generation of experimental acute myeloid leukemia in mice
Preprints

Fenghua Qian, Brooke E Arner, Shaneice K Nettleford, Robert F Paulson, K. Sandeep Prabhu

Released: 5-Aug-2022 12:00 PM EDT
A postnatal network of co-hepato/pancreatic stem/progenitors in the biliary trees of pigs versus humans
Preprints

Lola Reid, Wencheng Zhang, Giacomo Lanzoni, Eliane Wauthier, Sean Simpson, Amanda Allen, Carolyn Suitt, Juan Dominguez-Bendala, Vincenzo Cardinale, Domenico Alvaro, Diletta Overi, Eugenio Gaudio, Guido Carpino, Kyle Mathews,

Released: 5-Aug-2022 12:00 PM EDT
Study of the inflammatory activating process in the early stage of Fusobacterium nucleatum infected PDLSCs
Preprints

Qiang Feng, Yushang Wang, Lihua Wang, Tianyong Sun, Song Shen, Zixuan Li, Xiaomei Ma, Xiufeng Gu, Xiumei Zhang, Ai Peng, Xin Xu

Released: 5-Aug-2022 12:00 PM EDT
Central nervous system relapse in younger patients with diffuse large B-cell lymphoma - a LYSA and GLA/ DSHNHL analysis
Preprints

Catherine Thieblemont, Bettina Altmann, Fabian Frontzek, Loïc Renaud, Loic Chartier, Nicolas Ketterer, Christian Recher, Viola Poeschel, Olivier Fitoussi, Gerhard Held, René-Olivier Casasnovas, Corinne Haioun, Franck Morschhauser, Be



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