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Autoimmune Disease, Infectious Disease, Bone Marrow Transplant

Researchers Discover a New Gatekeeper Role for Thymic Dendritic Cells in Controlling T Cell Release into the Bloodstream

A team of scientists led by Julie Saba, MD, PhD at UCSF Benioff Children’s Hospital Oakland, has unveiled a novel role of thymic dendritic cells, which could result in new strategies to treat conditions such as autoimmune diseases, immune deficiencies, prematurity, infections, cancer, and the loss of immunity after bone marrow transplantation.

Medicine

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Dermatology, Dermatologist, Dermatologists, Indoor Tanning, Food & Drug Administration, Centers for Disease Control & Prevention

Research: Indoor Tanning Age Restriction Could Reduce Melanoma Incidence

An age restriction on indoor tanning could save thousands of lives and millions of dollars, according to new research published online in the Journal of the American Academy of Dermatology.

Medicine

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Prostate Cancer, Cancer, Men's Health, Men's Health Cancer Prevention, Inflammation, Inflammation And Prostate Cancer

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 6-Dec-2016 12:00 PM EST

Medicine

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Multiple Myeloma, Lymphoma, Hematology

Advances in Multiple Myeloma, Lymphoma and Other Hematologic Malignancies Presented at Annual Meeting of American Society of Hematology

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News release about significant new research findings in multiple myeloma, lymphoma and other hematologic disorders presented by researchers from University Hospitals Seidman Cancer Center and Case Western Reserve University School of Medicine at the 58th Annual Meeting of American Society of Hematology (ASH) in San Diego.

Medicine

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ASH Conference, Ash, American Society Of Hematology, Lymphoma, Acute Myeloid Leukemia, AML, hypomethylation, Yale Cancer Center

Alternative Option to Intensive Chemotherapy for Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)

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A Yale Cancer Center team has evaluated the use of hypomethylating agents in patients suffering from Acute Myeloid Leukemia (AML) who were resistant to treatment with intensive chemotherapy.

Medicine

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Nyu Langone, Catherine Diefenbach, Immunotherapy, Lymphoma, Ipilimumab, Yervoy, nivolumab, Adcentris, Opdivo, brentuximab vedotin, Perlmutter Cancer, ECOG-ACRIN

Combination Immune Therapy Shows Promise Against Hodgkin Lymphoma

The combination of two new drugs that harness the body’s immune system is safe and effective, destroying most cancer cells in 64 percent of patients with recurrent Hodgkin lymphoma, according to the results of an early-phase study.

Medicine

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Immunotherapy, Acute Myeloid Leukemia, Dr. Aude Chapuis, Fred Hutchinson Cancer Research Center, Fred Hutch, Bone Marrow Transplant

Immunotherapy Shows Promise in Preventing Leukemia Relapse

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Fred Hutchinson Cancer Research Center announced promising results from an early trial in which patients with high-risk acute myeloid leukemia received genetically engineered immune cells. Of the 12 AML patients who received this experimental T-cell therapy after a transplant put their disease in remission, all are still in remission after a median follow-up of more than two years.

Medicine

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Glioblastoma, NAD+ pathway, Nampt, NMN

Pathway Linked to Slower Aging Also Fuels Brain Cancer

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A metabolic pathway linked to slower aging is overactive in a deadly form of brain cancer, according to researchers at Washington University School of Medicine in St. Louis. Their findings suggest that tweaking the pathway to treat cancer may affect other biological processes, such as aging.

Medicine

Science

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alcohol use disorders, personality traits, Resilience, Genetics, Environment, risk, Influences

Resilience: A Small, Quiet Word with Huge Alcohol Use Disorder Implications

Certain personality traits – such as disinhibition (a lack of restraint) and impulsivity – increase the chances of developing alcohol use disorders (AUDs).

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TSRI Scientists Find Mechanism Behind Side Effects in Vision-Loss Treatment

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A common class of drugs for vision loss may actually add to the problem in some patients, according to new research co-led by scientists at The Scripps Research Institute (TSRI).

Medicine

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Hypertension, masked hypertension, Blood Pressure, white coat hypertension, Circulation

Study Reveals More Individuals May Have “Masked” Hypertension Than Thought

A new study shows that around the clock monitoring of blood pressure during daily activity revealed masked, or undetected, high blood pressure in a significant number of otherwise healthy adults who had normal readings in the clinic.

Medicine

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Mobile App Development , Chronic Disease, chronic disease management, Diabetes, Depression, Hypertension, Smartphone, mobile health, mhealth

A Missed App-Ortunity: Study Finds Few Mobile Health Apps Help Patients Who Need Them Most

The smartphones that nearly all Americans carry could transform how people manage their health, especially for those with complex health needs. But a new study suggests app makers are falling short when it comes to actually serving those who could get the most benefit from mobile health apps.

Medicine

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dental insurance, Medicare, Oral Health

Few Older Americans Have Dental Insurance

Only 12 percent of older Americans have some form of dental insurance and fewer than half visited a dentist in the previous year, suggests new Johns Hopkins Bloomberg School of Public Health research on Medicare beneficiaries.

Medicine

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DNA, endogenous retrovirus, Human Genome, provirus

BGSU Researcher: More Ancient Viruses Lurk in Our DNA Than We Thought

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In our recent study, we identified 19 “new” pieces of DNA — left by retroviruses that first infected our ancestors’ germlines hundreds of thousands of years ago –lurking between our own genes.

Medicine

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Concussion, CTE, Football, Mayo Clinic, Rochester Epidemiology Project

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 12-Dec-2016 12:05 AM EST

Medicine

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Digestive Health, IB, GI

Northwestern Memorial Hospital Named NPF Center for Pancreatitis

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The NPF is a nonprofit organization that provides hope for those suffering from pancreatitis and pancreatic cancer.

Medicine

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IBD, Inflammatory Bowel Disease, Widjaja, Dermot McGovern , Stephan Targan, Stephan R Targan, David Underhill

Cedars-Sinai Receives $10 Million for Pioneering Studies of Debilitating Digestive Tract Disease

Cedars-Sinai investigators in gastroenterology have been awarded $10 million by the National Institutes of Health to conclude a groundbreaking, decades-long investigation of the genetic and immunological causes of inflammatory bowel disease (IBD). This is the longest IBD study of its kind funded by the NIH and the first to explore the genetic makeup of the disease.

Medicine

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University of Pennsylvania School of Nursing, Penn Nursing Science, Penn Nursing, Nancy Hodgson, Dementia, Palliative Care, Alzheimer's Disease, Health Policy, health ethics, AMA Journal of Ethics

New Article by Penn Nursing Professor Examines Moral Obligation of Clinicians to Address the Needs of Family Caregivers of Persons with Dementia

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More than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current healthcare environment and reimbursement models emphasize obligations toward individual patients, preventing clinicians from reaching out to these caregivers to assess their needs and provide care.

Medicine

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Stem Cells, Cells, Ips Cells

Designer Switches of Cell Fate Could Streamline Stem Cell Biology

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Researchers at the University of Wisconsin-Madison have developed a novel strategy to reprogram cells from one type to another in a more efficient and less biased manner than previous methods.

Medicine

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Influenza, flu, Vaccine, Pharmaceticals, genes

New, More Effective Strategy for Producing Flu Vaccines

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A team of researchers led by Yoshihiro Kawaoka, professor of pathobiological sciences at the University of Wisconsin–Madison School of Veterinary Medicine, has developed technology that could improve the production of vaccines that protect people from influenza B.







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