Feature Channels: Immunology

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Newswise: T Cells Can Activate Themselves to Fight Tumors
Released: 8-May-2023 11:30 AM EDT
T Cells Can Activate Themselves to Fight Tumors
 University of California San Diego

UC San Diego scientists find an auto-signaling mechanism driving the T cell anti-tumor response; findings may inspire new cancer therapeutics and biomarkers.

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Newswise: A Key Biological Pathway for Multiple Sclerosis Is Uncovered by Mount Sinai Researchers
3-May-2023 11:30 PM EDT
A Key Biological Pathway for Multiple Sclerosis Is Uncovered by Mount Sinai Researchers
Mount Sinai Health System

Findings reveal a previously unknown way in which the brain and immune system talk to each other and may identify a new therapeutic target for MS and other brain disorders.

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Released: 8-May-2023 8:00 AM EDT
Adaptive immunity to ancient retroelements controls the skin tissue threshold of activation
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
The landscape of glioma-infiltrated immune cells after immune checkpoint blockade treatment
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Notch2 deficiency generates functionally impaired cDCs and macrophages that correlates with intestinal dysbiosis and low-grade inflammation
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
A combination of TLR9 and STING agonists induces potent neopeptide-specific T cell immunity and improves ICB efficacy in tumor models
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Microanatomical lipid niche controls intestinal memory B cell migration and effector function
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Pyruvate dehydrogenase operates as an intramolecular nitroxyl generator during macrophage metabolic reprogramming
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Single cell RNA sequencing reveals heterogenous immune landscape of tumor infiltrated immune cell population against glioblastoma
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Macrophages and neutrophils in lymph node granulomas from Mycobacterium tuberculosis-infected macaques have immunoregulatory phenotypes
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Robust T cell responses to the Pfizer/BioNTech vaccine compared to infection and evidence of attenuated CD8+ T cell responses due to COVID-19
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Oxidized phospholipid oxPAPC induces a dysfunctional Th1-like phenotype in regulatory T cells
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Pro-resolution lipid mediator maresin-1 reduces inflammation, promotes neuroprotection, and prevents disease progression in multiple sclerosis model of autoimmunity
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Cytometric analysis authenticates adjuvanticity of interferon-γ and suggests potential synergy with toll-like receptor agonists
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Longitudinal analysis reveals age-dependent immune responses to SARS-CoV-2 infection in a mouse model
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Effect of estrogen signaling in CD8 T cell mediated antiviral response
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Engineering antibody fusion proteins for targeted intracellular therapeutic delivery
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Design and characterization of a tumor-retained interleukin-2 cytokine/antibody fusion protein for cancer immunotherapy
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
A commensal-derived exopolysaccharide regulates ILC3-mediated diseases
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Cross-reactive seasonal coronavirus antibody responses contribute to antibody- mediated effector functions against SARS-CoV-2 in individuals in Kenya
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
IL-1 signaling directs the prioritization of inflammatory sites in a model of postoperative pulmonary infection
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Tunable dynamics of B cell selection in gut germinal centers
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Premature Treg induction in early life results in FoxP3 instability post-weaning
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Systems approaches to characterize the local heterogeneities in NK cell antitumor immunity in MHC I-disparate human non-small cell lung cancer
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
SARS-CoV-2 seroreversion is associated with a decrease in T cell functionality in children
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Design and optimization of a novel proteomimetic polymer nanoplatform for the co-delivery of antigens with adjuvants
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Tunable dynamics of B cell selection in gut germinal centers
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Reshaping the anti-tumor CD4 T-cell repertoire contributes to oncolytic virus therapeutic efficacy in malignant glioma
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
The glucose transporter GLUT4 tethers RIG-I-like receptors to suppress antiviral immunity
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Regulation of myeloid cells and inflammation marks increased susceptibility in a genetic model of acute viral infection-induced tissue damage
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Bio-active lipids protect against immune-related adverse events due to immune checkpoint blockade therapy
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Murine CD4+ T cells exhibit sexually dimorphic responses to estrogen signaling
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Prenatally educated friendly NK cells regulate allo-specific T cell responses through expansion of Foxp3+CD4+Treg cells and suppression of Type 1 and 17 CD8+T cell responses
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Dynamics of immune cells in the fetal brain upon viral inflammation
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Overlapping Mendelian disorders of immunity and metabolism shape CD4+ T cell immunometabolism
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Synergy between anti-commensal antibodies and IL-10 in gut homeostasis and disease
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Inhibition of distinct glycolytic enzymes produces differential effects on CD4 T cell function
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Diabetic wound keratinocytes induce macrophage JMJD3-mediated Nlrp3 expression via IL1R signaling
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
lntercellular mitochondria transfer rescues aerobic respiration in metabolically compromised macrophages in vitro and in vivo
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Mitochondrial metabolic flexibility is critical for CD8 T cell anti-tumor immunity
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Microanatomical lipid niche controls intestinal memory B cell migration and effector function
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Reshaping the anti-tumor CD4 T-cell repertoire contributes to oncolytic virus therapeutic efficacy
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Interferon-lambda accelerates viral clearance and regulates CD8+ T cells immunity in a murine model of SARS-CoV-2 infection
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
IL-10 promotes tissue-resident memory T cells (TRM) in the respiratory tract during SARS-CoV-2 infection in rhesus macaques
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Pre-existing immunity modulates responses to mRNA boosters
 American Association of Immunologists (AAI)

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Released: 8-May-2023 8:00 AM EDT
Synthetically mannosylated antigens impair the antigen-specific humoral immune response and prolong the therapeutic efficacy of immunogenic protein drugs
 American Association of Immunologists (AAI)

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Released: 5-May-2023 5:15 PM EDT
Study reveals insights into post-vaccine heart inflammation cases
 Yale University

When new COVID-19 vaccines were first administered two years ago, public health officials found an increase in cases of myocarditis, an inflammation of the heart muscle, particularly among young males who had been vaccinated with mRNA vaccines. It was unclear, however, what exactly was causing this reaction.

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Newswise:Video Embedded live-event-for-may-3-study-of-rebyota-fecal-microbiota-on-patients-with-c-diff-infection
VIDEO
Released: 5-May-2023 10:25 AM EDT
Video and transcript: Study of fecal microbiota on patients with C. diff infection
 Newswise

The researcher discusses the findings in a new study on the efficacy and safety of fecal microbiota (REBYOTA™), the first microbiota-based live biotherapeutic approved by the US FDA used to prevent recurrent Clostridioides difficile infection in adults.

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3-May-2023 4:25 PM EDT
Study Identifies Messages about Vaccinating Children Against COVID-19 That Resonate Best with Vaccine-Hesitant Parents
 Ann and Robert H. Lurie Children's Hospital of Chicago

A study from Ann & Robert H. Lurie Children’s Hospital of Chicago found that parents with children who were not yet vaccinated against COVID-19 were most likely to vaccinate their child after reading the following hypothetical scenario.

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Newswise: Gamma delta T cells can fight aggressive breast cancer
Released: 4-May-2023 7:20 PM EDT
Gamma delta T cells can fight aggressive breast cancer
 University of Freiburg

Researchers from the University of Frieburg discovered that coordinated differentiation and changes in the metabolism of breast cancer stem cells make them invisible for the immune system.

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