Feature Channels: Stem Cells

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Spinal cord injury (SCI) is damage to the spinal cord that leads to sudden loss of motor, sensory, ..

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Myocardial infarction (MI) results in irreversible loss of cardiomyocytes (CMs) and can often lead ..

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Cartilage injuries and disease are observed in a varied range of people; for instance, cartilage ..

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Objective: This is the first report on the safety and clinical efficacy of a bone marrow ..

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Current research in HIV treatment is oriented toward developing a therapeutic that can permanently ..

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Northern White Rhinos (NWR) are functionally extinct, with only two females left on the planet. ..

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Acute Lymphoblastic Leukemia (ALL) is a cancerous transformation in the blood and bone marrow ..

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Hearing loss affects millions of Americans in every age group, and it can be either conductive or ..

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In clinical medicine, hematopoietic stem cells have been utilized as a great source for disease ..

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Rasmani Hazra, Lily Brine, Libia Garcia, Brian Benz, Napon Chirathivat, Michael M Shen, John Erby Wilkinson, Scott Lyons, David L. Spector

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Jorge Zamora-Zaragoza, Katinka Klap, Jaheli Sánchez-Pérez, Jean-Philippe Vielle-Calzada, Ben Scheres

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Yu Zhao, Yingzhe Ding, Liangqiang He, Yuying Li, Xiaona Chen, Hao Sun, Huating Wang

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Jette Riecks, Balázs Győrffy, Ludwig Kiesel, Alberto Passi, Davide Vigetti, Martin Götte

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Pankaj Mogha, Shruti Iyer, Abhijit Majumder

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The goal of the current study was to investigate the therapeutic effects of exosomes derived from mesenchymal stem cells (MSCs-Exo) and copper sulfide nanoparticles (CuSNPs) as biomaterials in order to understand the mechanisms that contribute to …

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Osteosarcoma is a high-grade bone-forming neoplasm, with a complex genome. Tumours frequently show chromothripsis, many deletions, translocations and copy number alterations. Alterations in the p53 or Rb pathway are the most common …

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Rapid percutaneous coronary intervention for acute myocardial infarction (AMI) reduces acute mortality, but there is an urgent need for treatment of left ventricular dysfunction and remodeling after AMI to improve the prognosis. The myocardium …

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Human pluripotent stem cells (hPSCs) grow as colonies with epithelial-like features including cell polarity and position-dependent features that contribute to symmetry breaking during development. Our study provides evidence that hPSC colonies …

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Mesenchymal stem cells (MSCs) have recently emerged as an important candidate for cell therapy and tissue regeneration. However, some limitations in translational research and therapies still exist, such as insufficient cell supply, inadequate …

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Hematopoietic stem cell (HSC) transplantation is the only curative therapy for many diseases. HSCs from umbilical cord blood (UCB) source have many advantages over from bone marrow. However, limited HSC dose in a single CB unit restrict its …