Feature Channels: Stem Cells

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Released: 13-Jun-2022 12:00 PM EDT
Stretchable mesh microelectronics for the biointegration and stimulation of neural organoids
Preprints

Thomas L Li, Yuxin Liu, Csaba Forro, Levent Beker, Zhenan Bao, Bianxiao Cui, Sergiu P Pasca

Released: 13-Jun-2022 12:00 PM EDT
Nervous system reduction in branched-chain amino acid metabolism disrupts hippocampal neurogenesis and memory
Preprints

Khadar Abdi, Ramona Rodriguez, William C Wetsel, Michelle E Arlotto, Robert W McGarrah, Phillip J White

Released: 13-Jun-2022 12:00 PM EDT
Generation of Cerebral Organoids with Enriched Cortical Cellular Diversity and Outer Radial Glial Cell Identity from Human Pluripotent Stem Cells
Preprints

Yechiel Elkabetz, Sneha Arora, Anastasios Balaskas, Amèlia Aragonés Hernández, Daniel Rosebrock

Released: 13-Jun-2022 12:00 PM EDT
ΔNp63α Transcriptionally Represses p53 Target Genes Involved in the Radiation-Induced DNA Damage Response
Preprints

Ken-Ichi Kudo, Naohiro Tsuyama, Kento Nagata, Tatsuhiko Imaoka, Daisuke Iizuka, Misaki Sugai-Takahashi, Moe Muramatsu, Akira Sakai

Released: 12-Jun-2022 12:00 PM EDT
A Development-Inspired Niche for Homeostatic Human Mini-Intestines
Preprints

Charlie J Childs, Emily M Holloway, Caden W Sweet, Yu-Hwai Tsai, Angeline Wu, Joshua Wu, Oscar Pellon Cardenas, Meghan M Capeling, Madeline Eiken, Rachel Zwick, Brisa Palikuqi, Coralie Trentesaux, Charles Zhang, Ian Glass, Claudia Loebel, Qianhui Yu, Gray Camp, Jonathan Z Sexton, Ophir D Klein, Michael P Verzi, Jason J Spence

Released: 12-Jun-2022 12:00 PM EDT
Molecular phenotyping of colorectal neoplasia shows dynamic and adaptive cancer stem cell population admixture
Preprints

Ester Gil Vasquez, Nadia Nasreddin, Gabriel N Valbuena, Eoghan J Mulholland, Hayley L Belnoue-Davis, Holly Eggington, Ryan O Schenck, Valerie M Wouters, Pratyaksha Wirapati, Kathryn Gilroy, Tamsin R M Lannagan, Dustin J Flanagan, Arafath K Najumudeen, Sulochana Omwenga, Amy M B McCorry, Alistair Easton, Viktor H Koelzer, James E East, Dion Morton, Livio Trusolino, Timothy Maughan, Andrew D Campbell, Maurice B Loughrey, Philip D Dunne, Petros Tsantoulis, David J Huels, Sabine Tejpar, Owen Sansom, Simon J Leedham

Released: 12-Jun-2022 12:00 PM EDT
Angelman syndrome patient neuron screen identifies a potent and selective clinical ASO targeting UBE3A-ATS with long lasting effect in cynomolgus monkey
Preprints

Ravi Jagasia, Charlotte Bon, Soren V. Rasmussen, Solveig Badillo, Disa Tehler, Daniele Buchy, Marco Berrera, Megana Prasad, Marco Terrigno, Nikhil J. Pandya, Veronica Costa, Congwei Wang, Lykke Pedersen, Meghan T Miller, Kamille Dumong Erichsen, Lars Joenson, Joerg Hipp, Azad Bonni, Lutz Mueller, Annamaria Braendli-Baiocco, Thomas Kremer, Erich Koller, Marius Hoener

Released: 12-Jun-2022 12:00 PM EDT
Antiviral Therapy Defiant Polyviral Retinitis Post Hematopoietic Allogeneic Stem Cell Transplant
Preprints

Nadia Gabarin, Mili Roy, Alexander J. Kaplan, Shariq Haider, Dina Khalaf

Released: 11-Jun-2022 12:00 PM EDT
A two-step in vivo CRISPR screen unveils pervasive RNA binding protein dependencies for leukemic stem cells and identifies ELAVL1 as a therapeutic target
Preprints

Ana Vujovic, Laura P.M.H. de Rooij, Ava Keyvani Chahi, He Tian Chen, Brian Yee, Sampath K Loganathan, Lina Liu, Derek C.H. Chan, Amanda Tajik, Emily Tsao, Steven Moreira, Pratik Joshi, Joshua Xu, Nicholas Wong, Sasan Zandi, Stefan Aigner, John E. Dick, Mark D. Minden, Daniel Schramek, Gene W. Yeo, Kristin J Hope

7-Jun-2022 9:00 AM EDT
Stem-Cell Based Therapy Shows Promise in Treating High-Risk Type 1 Diabetes
Endocrine Society

An investigative stem cell-based therapy called PEC-Direct, designed to act as a replacement pancreas, has the potential to provide blood sugar control in patients with high-risk type 1 diabetes, suggests a clinical study presented Saturday, June 11 at ENDO 2022, the Endocrine Society’s annual meeting in Atlanta, Ga.

Newswise: Pediatric Urologist Dr. Anthony Atala to Receive 2022 Jacobson Innovation Award of the American College of Surgeons for Pioneering Work in Regenerative Medicine
Released: 10-Jun-2022 11:30 AM EDT
Pediatric Urologist Dr. Anthony Atala to Receive 2022 Jacobson Innovation Award of the American College of Surgeons for Pioneering Work in Regenerative Medicine
American College of Surgeons (ACS)

The Jacobson Innovation Award is an international surgical honor that recognizes living surgeons who are innovators of a new development or technique in any field of surgery. It is made possible through a gift from Julius H. Jacobson II, MD, FACS, and his wife Joan. Dr. Jacobson is a general vascular surgeon known for his pioneering work in the development of microsurgery. This year's recipient, Dr. Anthony Atala, is a pediatric urologist, researcher, professor, and mentor who is renowned for developing foundational principles for regenerative medicine research, which holds great promise for people who require tissue substitution and reconstruction.

Released: 9-Jun-2022 12:00 PM EDT
Hyaluronic acid biosynthesis promotes an invasive, stem-like cancer cell phenotype by broadly altering metabolism
Preprints

Adrian Adwait Shimpi, Matthew Lee Tan, Michael Vilkhovoy, David Dai, Ladeidra Monet Roberts, Joe Chin-Hun Kuo, Lingting Huang, Jeffrey Varner, Matthew J Paszek, Claudia Fischbach

Released: 9-Jun-2022 12:00 PM EDT
The Korean Undiagnosed Diseases Program Phase I: Expansion of the Nationwide Network and the Development of Long-term Infrastructures
Preprints

Soo Yeon Kim, Seungbok Lee, Hyewon Woo, Young Jun Ko, Youngkyu Shim, Soojin Park, Se Song Jang, Byung Chan Lim, Jung Min Ko, Ki Joong Kim, Anna Cho, Hunmin Kim, Hee Hwang, Ji Eun Choi, Man Jin Kim, Jangsup Moon, Moon-Woo Seong, Sung Sup Park, Sun Ah Choi, Ji Eun Lee, Young Se Kwon, Young Bae Sohn, Jon Soo Kim, Won Seop Kim, Yun Jeong Lee, Soonhak Kwon, Young Ok Kim, Hoon Kook, Yong Gon Cho, Chong Kun Cheon, Ki-Soo Kang, Mi-Ryoung Song, Hyuk-Jin Cha, Hee-Jung Choi, Yun Kee, Seung Tae Baek, Murim Choi, Jong-Hee Chae, Dong-Sung Ryu

Released: 9-Jun-2022 12:00 PM EDT
Alterations in neural stem cell quiescence and activation in the 3xTG-AD model of Alzheimer's Disease
Preprints

Yubing Liu, Bensun Cambell Fong, Richard A Harris, Marie-Michelle McNicoll, Amaal A Abdi, Jacob B Cuthbert, David P Cook, Daniel Figeys, Jing Wang, Barbara C Vanderhyden, Ruth S Slack



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