Feature Channels: Stem Cells

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Released: 14-Jan-2022 8:55 AM EST
Optimization of human umbilical cord blood-derived mesenchymal stem cell isolation and culture methods in serum-and xeno-free conditions
Stem Cell Research & Therapy

… Clearly, more experiments should be performed to elucidate the mechanism behind the morphology change of UCB-MSCs when co-culturing with cancer cells, as well as the effect of this stem cell type on cancer cells. Nevertheless, our initial …

Released: 14-Jan-2022 8:55 AM EST
Hypes and Hopes of Stem Cell Therapies in Dentistry: a Review
Stem Cell Reviews and Reports

… This review outlines the discoveries in the oral stem cell field, focusing on the latest advances in biological research, such as the formation … Of the various dental stem cell populations, both stem cell populations isolated from dental pulp - DPSCs …

Released: 14-Jan-2022 8:55 AM EST
Distinct properties of adipose stem cell subpopulations determine fat depot-specific characteristics
Cell Press

In mammals, white adipose tissues are largely divided into visceral epididymal adipose tissue (EAT) and subcutaneous inguinal adipose tissue (IAT) with distinct metabolic properties. Although emerging evidence suggests that subpopulations of …

Released: 14-Jan-2022 8:55 AM EST
Stem cell transplantation as a progressing treatment for retinitis pigmentosa
Cell and Tissue Research

… This review article mainly discusses the advances in application of stem cell and progenitor transplantation for retinitis pigmentosa. Stem cell sources such as mesenchymal stem cells, embryonic stem cells, induced pluripotent stem cells …

Released: 14-Jan-2022 8:55 AM EST
Coordinate control of basal epithelial cell fate and stem cell maintenance by core EMT transcription factor Zeb1
Cell Reports

… , but the molecular mechanisms that coordinately control basal cell fate and stem cell quiescence are elusive. Here, we report an epithelium-… stem cell function to Zeb1-deficient basal cells. Thus, Zeb1 is a transcriptional regulator that maintains …

Released: 14-Jan-2022 8:55 AM EST
Context-dependent transcriptional regulations of YAP/TAZ in stem cell and differentiation
Stem Cell Research & Therapy

… ESCs, isolated from the ICM in vitro, can propagate in vitro and differentiate into all adult cells, they therefore provide useful materials for stem cell research with strong potential in regenerative medicine. LeBlanc et al. have showed that Yap1/Tead4 …

Released: 14-Jan-2022 8:55 AM EST
The Puzzle of TAVR for Bicuspid AS: Still Missing a Piece?
Journal of Cardiothoracic and Vascular Anesthesia

… Despite a known high prevalence of anemia and periprocedural stroke risk among TAVR patients, few studies have evaluated the relationship between anemia and new ischemic lesions detected by DW-MRI. In this study, we revealed that …

Released: 14-Jan-2022 8:55 AM EST
Emilin-2 is a component of bone marrow extracellular matrix regulating mesenchymal stem cell differentiation and hematopoietic progenitors
Stem Cell Research & Therapy

… Emilin-2 expression was monitored in vitro in primary and mesenchymal stem cell lines under undifferentiated and adipogenic conditions. … Our data provide new insights in the contribution of bone marrow extracellular matrix microenvironment in …

Released: 14-Jan-2022 8:55 AM EST
Profiling biotoxicities of hexafluoropropylene oxide trimer acid with human embryonic stem cell-based assays
Journal of Environmental Sciences

… In this study, we investigated the cytotoxicity and hepatoxicity of HFPO-TA using human embryonic stem cell (hESC)-based assays. Results showed that HFPO-TA reduced hESCs’ viability in a dose dependent manner, and the calculated IC50 for …

Released: 14-Jan-2022 8:55 AM EST
Direct comparison of different therapeutic cell types susceptibility to inflammatory cytokines associated with COVID-19 acute lung injury
Stem Cell Research & Therapy

Although 90% of infections with the novel coronavirus 2 (COVID-19) are mild, many patients progress to acute respiratory distress syndrome (ARDS) which carries a high risk of mortality. Given that this dysregu...

Released: 12-Jan-2022 12:00 PM EST
PINK1 Kinase Enhances the Repair Effects of Bone Marrow Mesenchymal Stem Cells on Renal Ischemia/Reperfusion-Induced Acute Kidney Injury in Mice
Preprints

Chenyu Lin, Wen Chen, Yong Han, Yujie Sun, Xiaoqiong Zhao, Yuan Yue, Binyu Li, Wenmei Fan, Tao Zhang, Li Xiao

Released: 12-Jan-2022 12:00 PM EST
Clinical Predictors of Survival for Patients with Atypical Teratoid/Rhabdoid Tumors
Preprints

Vismaya S Bachu, Pavan Shah, Adrian E Jimenez, Adham M Khalafallah, Jignesh Tailor, Debraj Mukherjee, Alan R Cohen

Released: 12-Jan-2022 12:00 PM EST
Amniotic fluid stem cell extracellular vesicles promote fetal lung branching and cell differentiation in experimental congenital diaphragmatic hernia
Preprints

Kasra Khalaj, Rebeca Lopes Figueira, Lina Antounians, Sree Gandhi, Matthew Wales, Louise Montalva, George Biouss, Augusto Zani

Released: 11-Jan-2022 12:00 PM EST
Human amniotic mesenchymal stem cells combined with PPCNg facilitate injured endometrial regeneration
Stem Cell Research & Therapy

Caused by the injury to the endometrial basal layer, intrauterine adhesions (IUA) are characterized by uterine cavity obliteration, leading to impaired fertility. Human amniotic mesenchymal stem cells (hAMSCs)...

Released: 11-Jan-2022 12:00 PM EST
TrpA1 is a shear stress mechanosensing channel regulating intestinal homeostasis in Drosophila
Preprints

Jiaxin Gong, Niraj K. Nirala, Jiazhang Chen, Fei Wang, Pengyu Gu, Qi Wen, Y. Tony Ip, Yang Xiang

Released: 11-Jan-2022 12:00 PM EST
Polycrystalline Diamond Coating on Orthopaedic Implants: Realization, and Role of Surface Topology and Chemistry in Adsorption of Proteins and Cell Proliferation
Preprints

Justas Zalieckas, Ivan Rios Mondragon, Paulius Pobedinskas, Arne Skodvin Kristoffersen, Samih Mohamed-Ahmed, Cecilie Gjerde, Paul Johan Høl, Geir Hallan, Ove Nord Furnes, Mihaela-Roxana Cimpan, Ken Haenen, Bodil Holst, Martin Møller Greve

Released: 11-Jan-2022 12:00 PM EST
Mouse CHD4-NURD is Required for Neonatal Spermatogonia Survival and Normal Gonad Development
Preprints

Rodrigo Orlandini de Castro, Luciana Previato, Agustin Carbajal, Victor Goitea, Courtney T. Griffin, Roberto J. Pezza



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