1) Use of finasteride for prostate cancer prevention has not increased; 2) Experts expect a slow adoption of chemoprevention strategies.
1) Risk varied according to BMI, with greater risks for thinner women; 2) Longer duration of hormone therapy increased breast cancer risk.
Advances in cancer treatment and management have not affected all socioeconomic groups equally, as data shows minority patients tend to lag behind in both awareness and outcomes.
Premier international conference will highlight breakthroughs in diagnosis and patient management in an era of personalized medicine.
The American Association for Cancer Research's Chief Executive Officer, Margaret Foti, Ph.D., M.D. (h.c.), along with other AACR representatives, will ring the opening bell at the NASDAQ Stock Market on Tuesday, August 3, signaling the start of the day’s trading. The ceremony will be broadcast live on a seven-story video tower in New York City’s Times Square, and will stream live on the Internet.
1) Imatinib is the standard of care for chronic myeloid leukemia; 2) Fluorescence resonance energy transfer (FRET) may identify resistance; 3) FRET allows for more accurate treatment management.
Researchers at The University of Texas M. D. Anderson Cancer Center are testing a new technique for identifying circulating genetically abnormal cells, which can lead to poor prognosis, in patients with non-small cell lung cancer.
1) Reduction of 32 percent seen in a prospective cohort study; 2) Fish oil was previously shown to decrease heart disease risk; 3) Randomized, controlled trial planned at Harvard University.
The American Association for Cancer Research is currently accepting nominations for the prestigious 2010 AACR-Prevent Cancer Foundation Award for Excellence in Cancer Prevention Research.
1) Low-income women are often faced with competing priorities; 2) Family income was approximately $7,000 annually.
1) Caffeinated coffee protected against oral cavity, pharyngeal cancers; 2) Regular coffee drinkers had a 39 percent decreased risk of cancer.
The American Association for Cancer Research recognizes the first anniversary of the Family Smoking Prevention and Tobacco Control Act, which was signed into law by President Obama on June 22, 2009.
1) Oncogenic BRAF contributes to immune escape in melanoma; 2) MAPK pathway inhibition can release suppression; 3) BRAF inhibition improves T-cell immune response against cancer.
1) Phase III trial currently enrolling; 2) Clear tumor regression seen in preclinical models; 3) No increased toxicity observed.
1) Intervention improves survival rates following breast cancer recurrence; 2) Benefits were evident years after intervention ended.
1) Risk increased by twofold in Chinese men with low BMI; 2) Non-dairy foods were the largest contributors of calcium intake.
The American Association for Cancer Research registered more than 18,000 people from all over the world for its 101st Annual Meeting 2010 in Washington, D.C., which was held April 17-21. Registration increased by 19 percent from the 2009 Annual Meeting in Denver, Colo.
1) Risk higher than fourfold with some devices; 2) FDA currently considering a ban on indoor tanning beds among teens.
The American Association for Cancer Research Chief Executive Officer Margaret Foti, Ph.D., M.D. (h.c.), received the 2010 Philadelphia Pinnacle Award on May 22.
Two years after an historic fundraising telecast and the start of a groundbreaking grassroots movement, Stand Up To Cancer (SU2C) will return to primetime television on September 10, 2010, at 8PM EST & PST / 7PM CT, with a star-studded appeal to build continuing public support and donations for cutting-edge cancer research that translates at a rapid pace from the laboratory to treatments and technologies that benefit patients.
The American Association for Cancer Research, the world’s oldest and largest cancer research organization, congratulates Harold E. Varmus, M.D., on his nomination by President Barack Obama to serve as the 14th director of the National Cancer Institute (NCI).
1) Despite public health warnings, drinking is still high among pregnant women; 2) AML risk increased 56 percent among children of those who drank alcohol.
While previous research had suggested that drinking milk was related to factors that may increase the risk of renal cell cancer, results of a recent study exploiting the genetic contribution to variation in milk consumption suggest that this may not be the case.
Women who have a breast density of 75 percent or higher on a mammogram have a risk of breast cancer that is four to five times greater than that of women with little or no density, making mammographic breast density one of the strongest biomarkers of breast cancer risk.
• Heavy alcohol consumption accelerates telomere shortening. • Telomere shortening is linked to premature aging and cancer risk.
• EGFR levels are elevated prior to the breast cancer diagnosis. • High levels detected 17 months prior to diagnosis.
• Study expands on the established positive association between postmenopausal weight and breast cancer. • BMI increase of 5 kg/m2 or more between age 20 and study entry (ages 55-74) nearly doubled postmenopausal breast cancer risk.
Interest in cancer prevention is increasing as scientists continue to learn new information and confirm what was already suspected.
• Benign adenomas in the colon increased slightly in participants using statins. • Preliminary data suggesting statins may prevent colorectal cancer were not supported by this secondary analysis.
• Smokers who take metformin for diabetes have a lower incidence of cancer. • Metformin inhibits tumor growth; decreases circulating insulin and IGF-1 levels. • Metformin prevented development of lung tumors in lab animals.
• Ongoing, Phase I study of BBI608 shows early promise. • Enrollment and dose escalation are still underway.
• Higher Prostate Health Index and tissue DNA content are viable biomarkers. • Serum pro-prostate specific antigen levels didn’t predict cancer progression.
New research is emerging that suggests a link between infection-related diseases and risk of cancer, according to findings presented here at the American Association for Cancer Research 101st Annual Meeting 2010.
1) Nobel Laureate Elizabeth H. Blackburn, Ph.D., is new president. 2) Tyler Jacks, Ph.D., is past president. 3) Judy E. Garber, M.D., M.P.H., is president-elect. 4) William N. Hait, M.D., Ph.D., past president (2007-2008), is new treasurer. 5) Hait succeeds Bayard D. Clarkson, M.D., past president (1980-1981), who served an unprecedented five terms as treasurer.
In an update of the 19,490-patient Study of Tamoxifen and Raloxifene (STAR) P-2 trial in breast cancer prevention, both raloxifene and tamoxifen remain effective options to prevent breast cancer at 81 months of follow-up.
Scientists are methodically unlocking the biological processes that lead to cancer, and recent discoveries with microRNAs (miRNAs) are revolutionizing their understanding and leading to clinical trials of potentially effective treatments.
Cancer is a multifaceted disease that requires multiple approaches to diagnosis and management.
New findings from epidemiology and observational studies show an increased risk for cancer among Latino populations, but unique demographic characteristics suggest the problem may be worse than currently known.
• “Mythbusters” interactive program drew large community audience. • Participants’ knowledge of clinical trials increased by 20 percent. • Format to be tried again in rural areas.
• Risk of breast cancer was reduced by 30 to 40 percent. • Calcium works by enhancing DNA repair capacity. • Effect of vitamins is long term and independent of DNA repair capacity.
Lung cancer is the number one cause of cancer death in men and women, but huge randomized trials of thousands of patients have either failed completely or shown negligible survival differences.
The American Association for Cancer Research will gather at the nation’s capitol next week for its Annual Meeting, and key cancer research issues will be on the agenda for more than 17,000 attendees.
The American Association for Cancer Research issued an urgent call for immediate action to stem the global tide of tobacco-related death and suffering and to improve public health in a comprehensive policy statement on tobacco and cancer published today in Cancer Research, a journal of the American Association for Cancer Research.
Scientific breakthroughs in molecular targeting, translational cancer research and cancer prevention will take center stage when more than 17,000 scientists from around the world gather at the Walter E. Washington Convention Center, April 17-21, for the AACR 101st Annual Meeting 2010.
The American Association for Cancer Research will recognize 20 recipients of the AACR-Thomas J. Bardos Science Education Awards for Undergraduate Students at the AACR 101st Annual Meeting 2010, held April 17-21 in Washington, D.C.
In an effort to educate and inspire the future generation of cancer researchers, the American Association for Cancer Research is holding several programs for high school and undergraduate college students who are embarking on a career in science or medicine.
Minorities in Cancer Research (MICR), an AACR membership group more than 4,000 strong, will present a comprehensive program at the AACR 101st Annual Meeting 2010, April 17-21.
The American Association for Cancer Research will award 25 Minority Scholar in Cancer Research Awards at the AACR 101st Annual Meeting 2010, held April 17-21 in Washington, D.C.
The American Association for Cancer Research will recognize leaders in the minority cancer community with the Minority-Serving Institution Faculty Scholar in Cancer Research Awards. The 25 recipients will be honored at the AACR 101st Annual Meeting 2010, held April 17-21 in Washington, D.C.
Joseph Schlessinger, Ph.D., will receive the Pezcoller Foundation-AACR International Award for Cancer Research for elucidating the mechanism of action of receptor tyrosine kinases and their intracellular signaling pathways which led to discovery of new families of cancer drugs for the treatment of renal cancer and gastrointestinal stromal tumors.
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