A protein from algae may have what it takes to stop Severe Acute Respiratory Syndrome (SARS) infections, according to new research. A recent study has found that mice treated with the protein, Griffithsin (GRFT), had a 100 percent survival rate after exposure to the SARS coronavirus (SARS-CoV), as compared to a 30 percent survival for untreated mice.
Vitamin D may slow the progressive decline in the ability to breathe that can occur in people with asthma as a result of human airway smooth muscle (HASM) proliferation, according to researchers at the University of Pennsylvania.
Black Americans are nearly twice as likely to develop acute lung injury, or ALI, as white Americans, according to researchers at the Emory University School of Medicine in Atlanta. The study also revealed that black patients did not have a higher risk of in-hospital death when compared to white patients.
The inactivated flu vaccine does not appear to be effective in preventing influenza-related hospitalizations in children, especially the ones with asthma. In fact, children who get the flu vaccine are more at risk for hospitalization than their peers who do not get the vaccine, according to new research that will be presented on Tuesday, May 19, at the 105th International Conference of the American Thoracic Society in San Diego.
New estimates of the likelihood that a latent case of tuberculosis (TB) will become active have resulted in a roughly 50 percent increase over previous estimates of the number of people needed to be screened (NNS) to prevent an active infection, limiting the cost effectiveness of screening in many Center for Disease Control and Prevention (CDC)-defined risk groups, according to an analysis conducted by experts in the epidemiology of the disease.
Researchers in London have demonstrated the ability of adult stem cells from bone marrow (mesenchymal stem cells, or MSCs) to deliver a cancer-killing protein to tumors. The genetically engineered stem cells are able to home to the cancer cells, both in culture and in mouse models, and deliver TNF-related apoptosis-inducing ligand (TRAIL), destroying the tumor cells while sparing normal cells.
Patients with undiagnosed or untreated obstructive sleep apnea are especially vulnerable to the effects of sleep deprivation and even legal doses of alcohol when it comes to lowered driving performance and increased risk of vehicular accidents, according to new research to be announced on May 19 at the American Thoracic Society's 105th International Conference in San Diego.
The eyes may be the window into the soul, but they may also contain important medical information. According to new research to be presented at the American Thoracic Society's 105th International Conference in San Diego on May 19, patients with diabetes who have retinopathy should also be screened for obstructive sleep apnea (OSA).
Aerosol delivery of antibiotics via nanoparticles may provide a means to improve drug delivery and increase patient compliance, thus reducing the severity of individual illnesses, the spread of epidemics, and possibly even retarding antibiotic resistance.
Children of mothers who smoked during pregnancy and their early childhood years may be predisposed to take up smoking as teens and young adults, compounding the physical damage they sustained from the smoke exposure.
Chronic exposure to tobacco smoke in childhood may contribute to early emphysema later in life, according to new research. Environmental tobacco smoke (ETS) is known to be associated with a variety of serious health problems, but it had not previously been associated with the development of emphysema over the life course. The data will be presented on Tuesday, May 19, at the 105th International Conference of the American Thoracic Society in San Diego.
Babies born to obese mothers may have an increased risk of asthma, according to data from a new study to be presented on May 19 at the 105th International Conference of the American Thoracic Society in San Diego.
Research conducted seven years after the terrorist attacks on the World Trade Center (WTC) in New York City (NYC) found that children attending the socioeconomically and ethnically homogeneous elementary school closest to Ground Zero have high rates of self-reported asthma and airway obstruction.
Chronic asthma sufferers may find new relief in a simple, minimally invasive outpatient procedure known as bronchial thermoplasty, which uses controlled radiofrequency-generated heat to treat the muscles of the airways, preventing them from constricting and narrowing.
Women may be more susceptible to the lung damaging effects of smoking than men, according to new research by Inga-Cecilie Soerheim, M.D., and her colleagues from Channing Laboratory, Brigham and Women's Hospital and University of Bergen, Norway. They analyzed data from a Norwegian case-control study including 954 subjects with chronic obstructive pulmonary disease (COPD) and 955 controls. All were current- or ex-smokers, and the COPD subjects had moderate or severe COPD.
Healthcare workers in South Africa are at a significantly increased risk of developing drug-resistant tuberculosis, or XDR-TB, in a trend which threatens to further exacerbate the already beleaguered healthcare systems in sub-Saharan countries, according to results of a new study. Researchers say the results underscore the urgent need for stringent TB screening policies among healthcare workers in these areas.
New HIV therapies have prolonged lives and improved health for patients with HIV, but the treatments have also brought the longer-term effects of the disease into sharper focus.
Aside from the obvious and immediate health problems that patients undergoing mechanical ventilation face, those who recover often do so with profound loss of strength and mobility that can impair their daily functioning and even lead to increased risk of morbidity and mortality down the line. Now research shows that functional status may be restored earlier to ICU patients by performing daily interruptions in sedation paired with mobilization and exercise, as led by physical and occupational therapists.
Exposure to particulate matter has been recognized as a contributing factor to lung cancer development for some time, but a new study indicates inhalation of certain particulates can actually cause some genes to become reprogrammed, affecting both the development and the outcome of cancers and other diseases.
Individuals suffering from chronic obstructive pulmonary disorder (COPD) can experience significant savings in healthcare costs by employing a self-treatment program with the judicious use of medications, according to the results of a new study. The self-treatment program achieves these savings by reducing the duration of flare-ups.
Could sleep be a critical component to maintaining a healthy body weight? According to new research to be presented on Sunday, May 17, at the American Thoracic Society's 105th International Conference in San Diego, body mass index (BMI) is linked to length and quality of sleep in a surprisingly consistent fashion.
Cystic fibrosis patients may benefit from a new therapy that increases airway hydration, preventing the buildup of mucous, which is a key factor in the disease, according to researchers at Parion Sciences in Durham, N.C.
A new study using advanced cardiac imaging technology indicates that cardiac abnormalities experienced by some marathon runners following competition are temporary, and do not result in damage to the heart muscle. The study, conducted by researchers at the University of Manitoba, marked the first use of cardiac magnetic resonance imaging, or CMR, in a post-marathon setting.
A large, well-controlled, multi-national clinical trial program has demonstrated the effectiveness and safety of what may become the first FDA-approved medicine for idiopathic pulmonary fibrosis, or IPF.
New research suggests that patients newly diagnosed with obstructive sleep apnea (OSA) who use a short-course of the sleep aid, eszopiclone, when beginning continuous positive airway pressure (CPAP) therapy, are more adherent with therapy in six months.
Automated phone calling may help physicians solve a perennial problem: patients who don't take medicine prescribed for chronic health conditions.
Otana Jakpor is a junior at Woodcrest Christian High School, in Riverside, California, and that she is presenting research that she conducted herself, not with colleagues in a laboratory or patient-care setting. Otana, who will be the youngest researcher presenting at the conference, will present two abstracts during the International Conference, which is being held from May 15 to 20, in San Diego.
Practicing certain tongue and pharyngeal exercises may reduce symptoms of mild to moderate obstructive sleep apnea (OSA), according to new research being published in the second issue for May of the American Journal of Respiratory and Critical Care Medicine.
New research provides evidence for a link between vitamin D insufficiency and asthma severity. Serum levels of vitamin D in more than 600 Costa Rican children were inversely linked to several indicators of allergy and asthma severity, including hospitalizations for asthma, use of inhaled steroids and total IgE levels, according to a study that will appear in the first issue for May of the American Journal of Respiratory and Critical Care Medicine.
An urgently needed new tuberculosis vaccine cleared a vital step in testing, an important advance at time when a third of the world's population is believed to be have latent tuberculosis infection (LTBI), which, when re-activated, can cause full-blown disease.
Smoking cigarettes is not only the principle cause of chronic obstructive pulmonary disease (COPD), but it may change the body's immune responses to bacteria that commonly cause exacerbations of the disease, according to new research in a mouse model.
A tiny variation within a single gene can determine not only how quickly and well lungs grow and function in children and adolescents, but how susceptible those children will be to exposure to second-hand tobacco smoke, even in utero, according to researchers from the University of Southern California.
Patients with moderate to severe chronic obstructive pulmonary disease (COPD) exhibit a disordered breathing-swallowing pattern that may account for their higher risk of aspiration pneumonia, according to new research from the University of Pittsburgh.
March 24, 2009, will mark World TB Day. On this day around the world, the public health and scientific community will raise public awareness about tuberculosis and the challenges that remain in controlling it globally, such as the urgent need to develop new TB diagnostic, treatment and prevention tools.
A new study has found that a high waist circumference is strongly associated with decreased lung function"”independent of smoking history, sex, body mass index (BMI) and other complicating factors.
Diagnosing and treating obstructive sleep apnea may soon become much less expensive and arduous, thanks to new research showing that a simplified program using experienced nurses, home ambulatory diagnosis and auto-titrating continuous positive airway pressure (CPAP) machines to titrate CPAP pressures is not inferior to the traditional model which relies on specialist physicians and sleep studies.
New research shows that individual exacerbations in chronic obstructive lung disease (COPD) themselves increase the likelihood of repeat exacerbations, even after five days of full, asymptomatic recovery"”bad news for patients with COPD, where each exacerbation can drive the progression of the disease.
High summer temperatures, pushed higher by global climate change, may bring with them a spike in hospitalizations for respiratory problems, according to an analysis of data from twelve European cities, from Dublin to Valencia. The data comes from the "Assessment and Prevention of Acute Health Effects of Weather Conditions in Europe" (PHEWE), a multi-center, three-year collaboration between epidemiologists, meteorologists and experts in public health collaboration that investigated the short-term effects of weather in Europe.
There may be a new way to predict mortality in patients with idiopathic pulmonary fibrosis (IPF), a devastating disease that slowly petrifies the lungs. Most patients live only three years after diagnosis on average; however, some remain stable for many years, while for others, the disease progresses more rapidly.
For sufferers of obstructive sleep apnea (OSA), a new study shows that losing weight is perhaps the single most effective way to reduce OSA symptoms and associated disorders, according to a new study in the American Journal of Respiratory and Critical Care Medicine, one of the American Thoracic Society's three journals.
Two studies found that obesity and sleep disordered breathing are independently linked to insulin resistance and liver disease"” and that either alone is a cause for concern, but together, they equal a one-two hit to some of the most important metabolic pathways in the body. A third study found that OSA is linked to a sedentary lifestyle, also independent of obesity.
Mortality in patients with acute respiratory distress syndrome (ARDS) has not fallen since 1994, according to a comprehensive review of major studies that assessed ARDS deaths. This disappointing finding contradicts the common wisdom that ARDS mortality has been in steady decline.
A recent multi-center prospective study found that calibrating medications based on daily monitoring of the fractional exhaled nitric oxide (FENO) and symptoms in asthmatic children showed no significant improvement over medicating based on daily symptom monitoring alone. Please see links to full article and editorials under "contacts".
Adult Cystic Fibrosis patients can provide important information that helps to predict their prognosis, according to research that asked 223 adult CF patients to assess their own health and well-being.
Critically ill patients frequently have uncertain prognoses, but their families overwhelmingly wish that physicians would address prognostic uncertainty candidly, according to a new study out of the University of San Francisco Medical Center.
Some patients with severe asthma who also have allergic sensitivity to certain fungi enjoy great improvements in their quality of life and on other measures after taking an antifungal drug, according to new research from The University of Manchester in England.
New research in an animal model suggests that a diet high in inorganic phosphates, which are found in a variety of processed foods including meats, cheeses, beverages, and bakery products, might speed growth of lung cancer tumors and may even contribute to the development of those tumors in individuals predisposed to the disease.
Patients with idiopathic pulmonary fibrosis (IPF) are three times as likely to experience severe coronary events"”including heart attacks"”than people without the disease, according to a recent study that analyzed the risk of cardiovascular disease in nearly 1,000 patients with IPF and more than 3,500 matched controls.
Early detection of lung disease in cystic fibrosis (CF), combined with aggressive treatment in infants, may be the key to controlling the progression of the disease, according to a recent study. New research shows that contrary to previous scientific opinion, progressive lung damage in CF patients can begin as early as infancy even though lung function shortly after diagnosis is normal.
Long-term use of a macrolide antibiotic may reduce the frequency of exacerbations in patients with moderate to severe chronic obstructive pulmonary disease (COPD) by as much as 35 percent, according to a London-based study.
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