Scientists and industry leaders from around the world will gather in Boston Nov. 14-19, 2009, for the AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics International Conference, which will feature groundbreaking information on important cancer therapies in development.
1) Atypical ductal hyperplasia rate has declined over the past decade; 2) This decline is related to the decline in postmenopausal hormone therapy; 3) Atypical ductal hyperplasia associated with early stage cancers.
The AACR Frontiers in Cancer Prevention meeting is the location to learn about the latest in scientific breakthroughs and epidemiology regarding the prevention of one of the world’s deadliest diseases. This year’s conference brings together delegates from all over the world to discuss new information in genetics, diet, exercise and socioeconomic conditions that affect cancer incidence.
1) Current study focused on oral cancer; 2) Phase II study with 41 patients; 3) Still too early to make recommendations.
Now in its 32nd year, the CTRC-AACR San Antonio Breast Cancer Symposium remains the top venue for research and discovery in breast cancer. This year’s conference will bring together delegates from all over the world.
1) Study shows low cholesterol as a symptom of cancer rather than a cause; 2) Possible benefit of higher HDL and cancer risk; 3) Lower cholesterol may lower risk of high-grade prostate cancer.
Premier international conference highlights breakthroughs in drug development in Boston, Nov. 15-19, 2009.
The American Association for Cancer Research welcomes Michael J. Burton as the chief development officer and executive director of the AACR Foundation. Burton will head the AACR’s fundraising program and lead the effort to raise philanthropic revenues critical to the organization’s mission.
Although a wide spectrum of human papillomavirus is seen across the population of India, HPV-16 and HPV-18 are the most common types and a vaccination targeting these types could eliminate 75 percent of the cervical cancers in the region, according to data presented at the American Association for Cancer Research Frontiers in Basic Cancer Research Meeting.
The American Association for Cancer Research will host its first Frontiers in Basic Cancer Research Meeting in Boston from Oct. 8-11, 2009. The meeting is expected to draw nearly 500 leading scientists to present on high-profile topics like epigenetics, metastasis and systems biology, and create synergies among the many subfields of basic science.
Leptin, a molecule linked with obesity, may play a crucial role in predicting poor prognosis from thyroid cancer, at least in the Middle Eastern region of the world, according to data presented at the American Association for Cancer Research Frontiers in Basic Cancer Research Meeting.
1) Late effects of cancer therapy affect integration into society; 2) Marriage is predicted by height, physical functioning, cognitive outcomes.
The CTRC-AACR San Antonio Breast Cancer Symposium will honor two leading breast cancer researchers when it holds its 32nd annual meeting Dec. 9-13, in San Antonio.
1) Leukemia cell detection using a magnetic needle and nanoparticles; 2) First step in developing a sensitive, low-cost analysis of minimal residual disease.
1) Risk factors for glioma are largely unknown; 2) A link was found between glioma and early life physical activity.
The American Association for Cancer Research congratulates its president-elect Elizabeth H. Blackburn, Ph.D., and AACR member Carol W. Greider, Ph.D., for winning, along with Jack W. Szostak, Ph.D., the Nobel Prize in Medicine, for the discovery of how chromosomes are protected by telomeres and the enzyme telomerase.
The American Association for Cancer Research will hold its first conference devoted solely to basic science from Oct. 8-11, 2009, when it gathers for the Frontiers in Basic Cancer Research Meeting in Boston.
Approximately 90 percent of all cancer deaths are due to metastasis, which occurs when cancer cells shed from the primary tumor and develop secondary, sometimes microscopic, tumors in the body’s distant organs. Although medicine has made significant strides against the more than 200 diseases collectively known as cancer, metastasis continues to present a daunting challenge.
1) Stress from loneliness leads to increased tumor growth; 2) Decrease breast cancer risk by increasing social interaction.
1) Previous studies show estrogen prevents colorectal cancer; 2) Largest study suggesting a prognostic benefit from estrogen; 3) Colorectal cancer is the second leading cause of cancer death.
1) Fat cells have biological effects that impair chemotherapy; 2) Relapsing leukemia cells can be found in fat tissue; 3) Provides possible explanation for rate of relapse.
Margaret Foti, Ph.D., M.D. (h.c.), chief executive officer of the American Association for Cancer Research, will receive the inaugural European CanCer Organisation Award for Lifetime Achievement on Sept. 21, 2009, in Berlin. This award honors Foti’s outstanding contributions to cancer research and her remarkable scientific leadership in the worldwide cancer community.
1) Metformin is more effective than chemotherapy alone; 2) Study supports cancer stem cells hypothesis; 3) Laboratory study focused on breast cancer cells.
1) Lapatinib only benefited a subgroup of patients who developed a rash from toxicity; 2) Hepatocellular carcinomas are clinically, biochemically heterogeneous; 3) Drug was well-tolerated overall; 12 percent required a dose reduction.
1) Pathological damage to a normal pancreas induces autoimmune reactivity; 2) Immunological safeguards exist to prevent severe autoimmune consequences.
1) Chronic periodontitis increases risk; 2) Smoking may be a modifier.
1) Only 22 percent of screen-eligible patients are screened; 2) Insurance, regular visits are the number one predictor of screening; 3) Higher rates of screening lead to less cancer.
1) Cigarette smoking, overweight/obesity increases this risk; 2) Blacks are at an increased risk for mortality.
1) Overweight by age 21 linked to lower risk of localized, low-grade prostate cancer; 2) Overweight in older adulthood linked to increased risk of prostate cancer; 3) Risk varied across ethnic groups.
1) Hexokinase 2 linked with poor post-surgical prognosis; 2) Brain metastasis is a growing problem in breast cancer.
The American Association for Cancer Research is currently accepting nominations for the prestigious Pezcoller Foundation-AACR International Award for Cancer Research. Deadline for Nominations is September 15, 2009.
The American Association for Cancer Research celebrates the life and legacy of Senator Edward M. Kennedy (D-Mass.). Over the last half century, Senator Kennedy has stood as a tireless champion in the fight against cancer and was the driving force behind improving health care and research policy in the U.S. Senate.
1) Interplay of physiological parameters is crucial; 2) Positron emission tomography is a promising tool; 3) Future therapy may need to be adjusted based on these findings.
1) MicroRNAs provide a revolutionary diagnostic tool; 2) Measuring saliva is both non-invasive and effective.
1) Fatigue is a major side effect of radiotherapy; 2) Inflammation mechanism suggests possible treatment option; 3) Test done in breast and prostate cancer.
Research results indicate: Cancer incidence rates still high; Mortality decreasing due to prevention, treatment and screening.
1) Oral budesonide does not change gastrointestinal side effects; 2) Diarrhea occurred in 32.7 percent of patients using the drug; 3) The median 12 and 18 month survivals were excellent and favorable.
"¢ Commonality of surgery increases with greater risk of cancer "¢ Some women choose surgery as far as seven years after genetic risk testing "¢ Age influences patient's decision to undergo mastectomy, oophorectomy
Overall cancer risk increases 40 percent or more for U.S. Hispanics; Mexicans have the lowest cancer risk; Puerto Ricans have the highest risk; Cubans, Puerto Ricans quickly acquire a similar colorectal cancer risk as whites
1) Approximately 50 percent do not recommend the vaccine; 2) Those who hear scientific information more likely to recommend; 3) Study confined to Texas, but representative of national mood.
Research results indicate: Method of restricting calories is important in tumor prevention; Periods of restriction provide protection; Calorie restriction alters hormone levels, influences cancer risk.
Scientists around the world are on the cusp of breakthroughs in cancer research that will soon translate into the clinic and provide the tools doctors need to curb the burden of cancer.
1) Potential late-stage ovarian cancer therapy; currently none available; 2) Diphtheria-encoding genes delivered to tumor site by nanoparticles; 3) Laboratory research; possible human trials about 18 months away.
HPV Infection May Be Linked to Poor Head and Neck Cancer Survival Rates in African Americans: American Association for Cancer Research to Host Press Conference on New Study
1) Amount of PTEN protein predicts resistance; 2) Revolutionary mathematical modeling increases accuracy.
1) Circulating blood cells higher in pediatric patients with metastatic disease; 2) Endothelial cells most likely play a role in the development of cancer; Rare cells detected in adult cancer patients important in pediatric cancers.
The American Association for Cancer Research applauds President Obama's nomination of Francis S. Collins, M.D., Ph.D., to be the 16th director of the National Institutes of Health (NIH).
1) Greater number of lifetime ovulations linked to higher risk of death; 2) Earlier age of menarche increases risk of death.
1) Weight, diet and exercise affects chance of postmenopausal breast cancer; 2) Blood glucose, triglycerides, blood pressure levels significantly increased risk.
1) People open to using online genetic tests; 2) Study suggests genetic testing may be beneficial, but many questions remain; 3) Smokers likely to take steps toward quitting after using genetic test.
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