In a study of more than 36,000 women, researchers observed that smokers can reduce their risk of developing lung cancer by being physically active. However, they strongly caution that any relative benefit is dwarfed by the benefits gained from quitting smoking.
Cigarette smoking and concurrent infection with high levels of the virus associated with cervical cancer can increase cancer risk by as much as 27 times, according to a study published in the November 2006 issue of Cancer Epidemiology, Biomarkers & Prevention.
British researchers have developed a vaccine that stimulates colorectal cancer patients' immune systems to fight cancerous cells.
Personal choices, such as smoking and consumption of fatty foods, have long been linked to increased cancer risk. During recent years, scientists have been seeking to isolate a variety of lifestyle decisions that may stave off the onset of cancer or even reduce tumor formation in their early stages. The latest round of such studies include the impact of exercise on colon cancer in men, how aspirin consumption may negate the harmful effects of eating flame-broiled meat, and a new link between child bearing and lung cancer.
At the American Association for Cancer Research's Frontiers in Cancer Prevention Research meeting, investigators have found that eating fish regularly as an adult, or soy as a young girl, or using a specific vitamin if you are a smoker, can help to protect against development of certain cancers. The researchers say these studies provide some of the strongest links found to date between diet and cancer.
Scientists are using genetic studies and natural chemicals, such as plant-derived triterpenoids, to further our knowledge on how genetic and early molecular interactions can lead to cancer, and how those early interactions can be manipulated to stave off a variety of cancers. The latest studies with new and promising chemopreventive agents were presented at the American Association for Cancer Research's Frontiers in Cancer Prevention Research meeting today.
The immune system is fickle, and easily influenced by more than just viruses and bacteria. It can be swayed by the seemingly unexpected, such as by what we eat, for example, and affected by surprising sources. At the American Association for Cancer Research's Frontiers in Cancer Prevention Research meeting, scientists are taking a closer look at the link between increasingly common lifestyle factors, the immune system and cancer, with the ultimate goals of preventing and better understanding cancer development.
The science of cancer prevention has advanced to the point where researchers now say they can detect "cancer genes" in the breath of smokers, and can test the presence of two proteins in men they say will predict development of prostate cancer a decade in advance.
Human papillomaviruses (HPV) are the most common sexually transmitted infections in the United States, and certain "high risk" types have been shown to cause cervical cancer. Despite recent advances in the detection and prevention of HPV, the link between the virus and cervical cancer is not well known to the public. In June 2006, the Food and Drug Administration (FDA) approved the first vaccine to prevent infection of two high risk types of HPV, and two types that cause genital warts.
A diagnosis of breast cancer has taken on a new meaning in the past 10 years, as research has produced a host of new therapies and detection techniques, significantly improving long-term survival for women who have been fighting the disease. To build on these successes, researchers are now harnessing what they have learned about treating breast cancer and applying it to possible methods of prevention to reduce the total incidence of the disease.
Stephen S. Hecht, an internationally recognized expert on cancer-causing agents in tobacco and the pathways by which they cause cancer, has been selected to receive the fifth annual American Association for Cancer Research (AACR)-Cancer Research and Prevention Foundation (CRPF) Award for Excellence in Cancer Prevention Research.
During the fifth annual International Conference on Frontiers in Cancer Prevention Research, the American Association for Cancer Research (AACR) is sponsoring a series of press briefings. Following brief presentations by participating investigators, questions will be fielded from members of the press. These briefings are only open to members of the media.
The best initial cervical cancer screening tool for younger women is still the traditional Pap smear. However, a large Danish study has found that for older women (age 40 and older), a test for human papillomavirus (HPV) is a much more effective way to screen for potential cancer.
The American Association for Cancer Research today announces a $635,000 gift from the Pancreatic Cancer Action Network (PanCAN) which significantly increases its grantmaking potential for young cancer scientists.
Chemicals found in grape seeds significantly inhibited growth of colorectal tumors in both cell cultures and in mice, according to researchers who have already demonstrated the extract's anti-cancer effects in other tumor types.
The American Association for Cancer Research today announces a $200,000 gift from the Breast Cancer Research Foundation which will create the BCRF-AACR Fund for Translational Breast Cancer Research.
A chemically altered form of vitamin E mixed into mouse chow dramatically reduced spread of aggressive mammary cancer in mice, suggesting that the compound in pill form could be used to treat human metastatic cancer, according to a report in the October 1 issue of the journal Cancer Research.
American Association for Cancer Research Chief Executive Officer Margaret Foti, Ph.D., M.D. (h.c.) will receive the Association of American Cancer Institutes (AACI) Distinguished Service Award for her outstanding contributions to progress in cancer research. The award will be presented during a special ceremony at the AACI's annual meeting, October 22 "“ 24, 2006.
If an anti-angiogenic drug is successfully starving a cancer patient's tumor to death, the number of endothelial cells circulating in the individual's bloodstream will decrease, thus providing a potential biomarker for gauging the medication's effectiveness, according to National Cancer Institute (NCI) research.
A test that measures the amounts of two members of the same protein family - one of which appears to act as an oncogene, and the other as a tumor suppressor - helps identify patients with breast cancer who will likely benefit from chemotherapy and those who won't, according to researchers.
Researchers have found that the same gene mutation responsible for a tepid response to Gleevec (imatinib) in treatment of gastrointestinal stromal tumors (GIST), bestows benefit when a newer targeted therapy, Sutent (sunitinib), is used.
A common laboratory test that predicted poor outcome from traditional radiation and chemotherapy treatment for head and neck cancers now has been found to predict a good prognosis with treatment of p53 tumor suppressor gene therapy - making it potentially the first predictive biomarker test for a gene-based drug.
Levels of a protein called thymidylate synthase (TS) within two separate compartments of a tumor cell"”the nucleus and the cytoplasm"”may be critical markers predicting survival in colorectal cancer, according to a study at Yale University School of Medicine.
Researchers have devised a new method to detect a spectrum of known gene mutations in a variety of cancer genes that they say is both sensitive and cost-effective. They say that if validated, this method of genotyping might ultimately be used in "real time" to match patients to available targeted therapies.
Scientists at a Maryland-based pharmaceutical company have preliminary evidence showing that a protein in the blood may prove to be a biomarker that is more sensitive and specific than current methods of early detection for prostate cancer.
In the U.S., a novel technology soon may be available to detect the spread, or metastasis, of breast cancer earlier than now possible, according to research presented at the first international meeting on Molecular Diagnostics in Cancer Therapeutic Development, organized by the American Association for Cancer Research.
Patients with melanoma of the eye are at risk for liver metastases, which are often not detected until they have turned into large, lethal tumors. Now researchers have found molecular markers, including changes in a particular chromosome, that flag the presence of small metastases before they reach life-threatening size.
Two genes, known as REG1A and EXTL3, are overexpressed in colorectal tumors of patients who are at high risk of recurrence, according to a new study from the Max Delbrueck Center in Berlin, Germany.
Lung cancer is a formidable disease. While it is one of the most preventable cancers, with the vast majority of 160,000 annual deaths in the United States due to smoking, it is invariably difficult to find early when it is most amenable to treatment. As a result, it remains the top cancer killer in the nation.
A team of researchers at Purdue University has found a protein in the blood that may prove to be more reliable than the standard prostate specific antigen (PSA) test in measuring the extent of prostate cancer.
Angiogenesis inhibitors can be far more effective in treating metastatic clear cell renal cell cancer (RCC) - an aggressive form of the most common kind of kidney cancer that is also rich in blood supply - than traditional treatments, according to accumulating evidence. They can prolong life in about a third of patients, but researchers have not been able to identify the responding patients, prior to treatment.
Raloxifene protects postmenopausal women from developing invasive breast cancer whether they are at high or low risk of developing the disease, according to a new study.
Consumption of Vitamin D tablets was found to cut the risk of pancreatic cancer nearly in half, according to a study led by researchers at Northwestern and Harvard universities.
Continuing a nearly 50-year-old tradition of honoring outstanding achievement in cancer research, the American Association for Cancer Research currently is accepting nominations for its series of annual awards. Scientists advancing the understanding and eradication of cancer through basic research, clinical care, therapeutics and prevention are eligible. Winners will help the AACR fulfill its mission to promote professional education and communications by delivering a lecture during the AACR's Centennial Year Annual Meeting, April 14-18, 2007, in Los Angeles, Calif.
Each year, cancer researchers around the world mark their calendars for what has become the premier international meeting on cancer prevention "“ the AACR Frontiers in Cancer Prevention Research meeting. It's here where the latest advances are revealed, offering the first glimpse into the translational research discoveries from the leading basic, clinical, epidemiologic, and behavioral scientists in the cancer field.
The American Association for Cancer Research to host first-ever meeting on potential breakthroughs in personalized medicine.
The American Association for Cancer Research (AACR), the world's oldest and largest cancer research organization, congratulates Dr. John E. Niederhuber on his appointment as Director of the National Cancer Institute.
Stem cell-like glioma cancer cells that share many characteristics with normal stem cells propel the lethal growth of brain cancers by promoting tumor blood vessel formation, and may hold the key to treating these deadly cancers, a research team reported in the August 15th issue of Cancer Research.
The Premier International Meeting: Molecular Diagnostics in Cancer Therapeutic Development - The American Association for Cancer Research to Host First-Ever Meeting on Potential Breakthroughs in Personalized Medicine. September 12-15, 2006, Hyatt Regency Chicago Hotel, Chicago, Ill.
So-called "DES daughters," born to mothers who used the anti-miscarriage drug diethylstilbestrol during pregnancy, are at a substantially greater risk of developing breast cancer compared to women who were not exposed to the drug in utero.
Scientists involved in cancer research, cancer medicine, or cancer-related biomedical science can nominate a colleague or professional associate for the 10th Pezcoller Foundation-AACR International Award for Cancer Research. The award was established in 1997.
John T. Hunt, Ph.D., executive director of oncology drug discovery at Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, N.J., has been voted Chairperson-elect of the Chemistry in Cancer Research Working Group of the American Association for Cancer Research (CICR/AACR). He will accede to the office of chairperson in April 2007 at the 98th Annual Meeting in Los Angeles, Calif.
The risk for developing the tissue abnormalities, or lesions, that typically precede cervical cancer is much higher for women infected with multiple genotypes of the human papillomavirus (HPV) than previously reported, according to a study published in the July issue of Cancer Epidemiology, Biomarkers & Prevention.
The AACR announces the first 11 recipients of the new Jeannik M. Littlefield-AACR Grants in Metastatic Colon Cancer Research. The awards, ranging to $250,000, were established in February 2006, to support innovative research projects designed to accelerate the discovery and development of new agents to treat metastatic colon cancer.
Pomegranate juice packs a punch on prostate cancer that prolongs post-surgery PSA doubling time, drives down cancer cell proliferation and causes prostate cancer cells to die, according to a study published in the July 1 issue of Clinical Cancer Research.
The American Association for Cancer Research is pleased to invite nominations for the sixth annual Landon-AACR Prizes for Basic and Translational Cancer Research. Nominations will be open until August 10, 2006.
When mom or dad puffs on a cigarette, their infants may inhale the resulting second-hand smoke. Now, scientists have detected cancer-causing chemicals associated with tobacco smoke in the urine of nearly half the babies of smoking parents.
Nominations are open for the annual American Association for Cancer Research-Cancer Research Prevention Foundation Award for Excellence in Cancer Prevention Research.
Researchers at the University of California, Los Angeles have defined conditions associated with disabling fatigue that persists for years in almost a third of breast cancer survivors, according to a study in the May 1 issue of Clinical Cancer Research.
Currently, physicians cannot predict which patients with prostate cancer should receive extra therapy after surgery or whether some of these patients have an indolent disease that does not even require surgery. Most patients with colorectal cancer have surgery, but some could benefit from additional treatment if physicians only knew who.
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