A protein associated with cancer progression when abundant inside of tumors also unexpectedly regulates the creation of new blood vessels that feed the tumor outside, a research team led by scientists at The University of Texas MD Anderson Cancer Center reports in the August edition of Cancer Cell.
A team of investigators led by a physician-scientist at The University of Texas MD Anderson Cancer Center has shown for the first time that the small protein SUMO can team up with the replication protein A (RPA) complex to facilitate DNA repair. The study is published in the Aug. 13 edition of the journal Molecular Cell.
Researchers have discovered an enzyme crucial to a type of DNA repair that also causes resistance to a class of cancer drugs most commonly used against ovarian cancer.
The University of Texas MD Anderson Cancer Center remains the leading hospital in the nation for cancer care for the fourth year straight, according to the annual "Best Hospitals" survey published by U.S. News & World Report.
Just one year after The University of Texas MD Anderson Cancer Center launched its secured, Web-based portal for personal health information, more than 28,000 patients (57 percent) who logged into myMDAnderson - a personalized, online connection to the center - have accessed their personal medical information, test results and records.
Margaret M. Fields, an advanced practice nurse in The University of Texas MD Anderson Cancer Center Department of Gynecologic Oncology, is the recipient of the 2010 Ethel Fleming Arceneaux Outstanding Nurse-Oncologist Award, made possible by The Brown Foundation, Inc.
Leading Gulf Coast medical centers, universities and public health institutions from Miami to Houston have united to form a consortium to improve community disaster readiness and recovery through research programs targeting health disparities, disaster preparedness and environmental health.
Oropharyngeal cancer patients whose tumors in the upper part of the throat test positively for the human papillomavirus (HPV) have better overall survival than patients with HPV-negative disease, researchers from The University of Texas MD Anderson Cancer Center report in a study published in The New England Journal of Medicine.
Family members can help reduce an aging relative’s risk of cancer by encouraging healthy lifestyle changes. Experts at The University of Texas MD Anderson Cancer Center offer suggestions for improving seniors' health.
Dasatanib, a medication currently approved as treatment for drug-resistant chronic myeloid leukemia (CML), provided patients with quicker, better responses as a first therapy than the existing front-line drug, according to researchers at The University of Texas MD Anderson Cancer Center.
Selenium, a supplement taken daily by millions in hopes of protection against cancer and a host of other diseases, has proven to be of no benefit in reducing a patient's risk of developing lung cancer - either a recurrence or second primary malignancy, according to results of an international Phase III clinical trial.
When combined with standard chemotherapy, an international Phase III trial has shown that the oral targeted therapy vandetanib improves progression-free survival for patients with advanced non-small cell lung cancer, according to research from The University of Texas MD Anderson Cancer Center.
In the first scientific study of its kind, shark cartilage extract, AE-941 or Neovastat, has shown no benefit as a therapeutic agent when combined with chemotherapy and radiation for patients with advanced non-small cell lung cancer, according to researchers at The University of Texas MD Anderson Cancer Center.
Evaluating its change over time, CA-125, the protein long-recognized for predicting ovarian cancer recurrence, now shows promise as a screening tool for early-stage disease, according to researchers at The University of Texas MD Anderson Cancer Center.
A study by a pediatric surgical oncologist from The University of Texas MD Anderson Children's Cancer Hospital shows that an adult surgery adapted for use in young patients increased the survival of children with rare tumors in the abdomen.
Janet Davison Rowley, M.D., trail-blazing researcher on the role of genetic variation in cancer, mentor of young scientists and role model for the possibilities of work-life balance, is the second winner of the Margaret Kripke Legend Award from The University of Texas MD Anderson Cancer Center.
Experts at The University of Texas MD Anderson Cancer Center are encouraging women to be creative and use parasols to protect delicate skin from the sun.
Human adult stem cells injected around the damage caused by a heart attack survived in the heart and improved its pumping efficiency for a year in a mouse model, researchers at The University of Texas MD Anderson Cancer Center report online ahead of publication in Circulation Research. Injection of a patient’s own adult stem cells into the heart has shown some efficacy in assisting recovery after a heart attack in early human clinical trials, said study senior author Edward T. H. Yeh, M.D. “But nobody knows how they work, or how long the stem cells last and function in the heart,” Yeh said. “This study shows how one type of adult stem cell works.”
Early life exposure to ultraviolet A light does not cause melanoma in a fish model that previously made that connection, scientists from The University of Texas MD Anderson Cancer Center reported today in the online Early Edition of the Proceedings of the National Academy of Sciences. UVA exposure is unlikely to have contributed to the rise in the incidence of melanoma over the past 30 years, the researchers conclude.
Recognized for his 20-year commitment to the science of cancer vaccines, specifically a personalized therapy for follicular lymphoma, Larry Kwak, M.D., Ph.D., professor and chair of the Department of Lymphoma and Myeloma at The University of Texas M. D. Anderson Cancer Center, has been named to the 2010 TIME 100.
The increasing number of minorities diagnosed with cancer has inspired a variety of initiatives at The University of Texas M. D. Anderson Cancer Center focusing on minority health through research, education and community relations.
Experts from the Children's Cancer Hospital at the University of Texas M. D. Anderson Cancer Center help parents understand the disease.
People who eat meat frequently, especially meat that is well done or cooked at high temperatures, may have a higher chance of developing bladder cancer, according to a large study at The University of Texas M. D. Anderson Cancer Center presented at the American Association for Cancer Research 101st Annual Meeting 2010. This risk appears to increase in people with certain genetic variants.
The first lung cancer clinical trial to guide targeted therapies to patients based on molecular signatures in tumor biopsies is a step toward personalized care and more effective, efficient clinical trials for new drugs, study leaders reported today during the American Association for Cancer Research 101st Annual Meeting 2010.
Overexpression of a specific type of microRNA can derail treatment by disabling an important molecular brake on breast cancer cell proliferation, according to evidence presented by researchers from The University of Texas M. D. Anderson Cancer Center at the American Association for Cancer Research 101st Annual Meeting 2010.
A class of brain tumor that tends to emerge in younger patients but is less aggressive than others can be identified by examining DNA methylation of a specific set of genes, scientists at The University of Texas M. D. Anderson Cancer Center and colleagues with The Cancer Genome Atlas report today online at Cancer Cell.
Chronic stress triggers a chain of molecular events that protects breakaway ovarian cancer cells from destruction, a team of researchers led by scientists at The University of Texas M. D. Anderson Cancer Center reports April 12 in the early online publication of the Journal of Clinical Investigation.
The molecular machinery that switches on a gene known to cause breast cancer to spread and invade other organs has been identified by an international team led by scientists at The University of Texas M. D. Anderson Cancer Center. The paper was published Sunday in Nature Cell Biology’s advanced online publication.
In an ongoing effort to scientifically validate the age-old belief that mind-body interventions have a beneficial impact on the health of patients, The University of Texas M. D. Anderson Cancer Center has been awarded more than $4.5 million to study the efficacy of incorporating yoga into the treatment program of women with breast cancer.
Researchers from the Children’s Cancer Hospital at The University of Texas M. D. Anderson Cancer Center may have found a way to more accurately predict treatment outcomes in young leukemia patients using information from a common and simple complete blood count test, also known as a CBC.
A two-drug combination destroys precancerous colon polyps with no effect on normal tissue, opening a new potential avenue for chemoprevention of colon cancer, a team of scientists at The University of Texas M. D. Anderson Cancer Center reports in the advance online edition of the journal Nature.
For Hempstead resident Lynette Love, mother of four and grandmother of five, surviving colorectal cancer took courage, diligence and faith. Now a 3-year survivor, Love is giving the love back to the community through her participation in the Sprint for Colorectal Oncology Prevention and Education (SCOPE) run.
Increased understanding of the Skp2 gene and its relation to cellular senescence may lead to the development of novel agents that can suppress tumor development in common types of cancer, researchers from The University of Texas M. D. Anderson Cancer Center and Memorial Sloan-Kettering Cancer Center report in the journal Nature.
A study from The University of Texas M. D. Anderson Cancer Center reports that cancer centers in the United States provide patients and their families with palliative care, though the depth, range and integration of programs and services widely vary.
The film "Avatar" isn't the only 3-D blockbuster making a splash this winter. A team of Houston scientists this week unveiled a new technique for growing 3-D cell cultures, a technological leap from the flat petri dish that could save millions of dollars in drug-testing costs. The research is reported in Nature Nanotechnology.
Experts at The University of Texas M. D. Anderson Cancer Center encourage people to review their polyp report.
Breast cancer patients with early stage disease that has spread to only one lymph node may not benefit from radiation after mastectomy, because of the low present-day risk of recurrence following modern surgery and systemic therapy, a finding that could one day change the course of treatment for thousands of women diagnosed each year, according to researchers at The University of Texas M. D. Anderson Cancer.
In a new study from The University of Texas M. D. Anderson Cancer Center, researchers found that cystoscopy, the standard for screening for recurrence of early-stage bladder cancer, is a cost-effective method of detecting tumors.
Researchers from The University of Texas M. D. Anderson Cancer Center have developed a new assessment tool to measure the severity of symptoms that can complicate stem cell transplantation. The tool assesses symptoms resulting from chronic graft-versus-host disease (cGVHD), and was presented with supporting research at the 2010 Bone and Marrow Transplant Tandem Meeting.
Contralateral prophylactic mastectomy (CPM), a preventive procedure to remove the unaffected breast in patients with disease in one breast, may only offer a survival benefit to breast cancer patients age 50 and younger, who have early-stage disease and are estrogen receptor (ER) negative, according to researchers at The University of Texas M. D. Anderson Cancer Center.
A comprehensive screening of peptide targeting agents and follow-up analysis produce two small-molecule drugs that attack EGFR and VEGFR pathways in novel ways.
Isaiah J. Fidler, D.V.M, Ph.D., a pioneer in understanding how cancer spreads to other organs and then taps its new environment to thrive and grow, has received the Lifetime Achievement Award from Nature Publishing at the 2010 Miami Winter Symposium - Targeting Cancer Invasion and Metastasis.
ATM, a protein that reacts to DNA damage by ordering repairs or the suicide of the defective cell, plays a similar, previously unknown role in response to oxidative damage outside of the nucleus, researchers report this week in the online version of the Proceedings of the National Academy of Sciences.
M. D. Anderson researchers find better way to predict prognosis in patients treated with aromatase inhibitors; research also suggests a potential means of circumventing drug resistance.
Being active for at least 30 minutes every day reduces your risk of developing some types of cancer. Fitness experts at The University of Texas M. D. Anderson Cancer Center have designed an exclusive exercise plan based on this evidence that will fit into almost anyone’s lifestyle.
Leukemia cells, like most cancers, are addicted to glucose to generate their energy, but new research shows for the first time that these cells also rely on fatty acid metabolism to grow and to evade cell death.
Cancer-initiating cells that launch glioblastoma multiforme, the most lethal type of brain tumor, also suppress an immune system attack on the disease, scientists from The University of Texas M. D. Anderson Cancer Center report in a paper featured on the cover of the Jan. 15 issue of Clinical Cancer Research.
Expert at The University of Texas M. D. Anderson Cancer Center provide insight to parents based on what we've learned about about the HPV vaccine in the past four years.
CAN DO Houston (Children and Neighbors Defeating Obesity) will expand its community-based efforts with a $360,000 grant from the Robert Wood Johnson Foundation’s “Healthy Kids, Healthy Communities” initiative.
A growth factor that is a common target of cancer drugs also plays an important role in the heart's response to stress, researchers at The University of Texas M. D. Anderson Cancer Center report online this week in the Journal of Clinical Investigation.
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