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Released: 30-Mar-2002 12:00 AM EST
Molecular Studies May Accelerate Research on Blood Diseases, Cancers
UT Southwestern Medical Center

Two studies led by a UT Southwestern Medical Center at Dallas scientist have revealed comparable genes that control what cells become in both mice and a common worm, findings that may lead to expediting research on human-blood diseases.

Released: 23-Mar-2002 12:00 AM EST
How Common Multiple Sclerosis Drug Slows Progression of the Disease
UT Southwestern Medical Center

A common drug given to multiple sclerosis patients appears to stimulate weakened immune system cells, according to a study published by researchers at UT Southwestern Medical Center at Dallas.

Released: 13-Mar-2002 12:00 AM EST
New Implant Product Used by Plastic Surgeons Fills Out Thin Lips and Facial Creases
UT Southwestern Medical Center

Until now, the only option for women who wanted to plump up thin lips was either lip-liner makeup or collagen injections that work only temporarily. But a new synthetic material used by plastic surgeons at UT Southwestern Medical Center at Dallas offers a permanent alternative that creates fuller, more defined lips.

8-Mar-2002 12:00 AM EST
Human Lymphomas Linked to Polio Vaccine Tainted with Monkey Virus
UT Southwestern Medical Center

UT Southwestern researchers have established a link between human non-Hodgkins lymphomas and a monkey virus carried by some people, possibly opening new avenues for detection, prevention and treatment.

Released: 7-Mar-2002 12:00 AM EST
Leptin Replacement Therapy Reduces Metabolic Abnormalities
UT Southwestern Medical Center

Leptin replacement therapy drastically reduces triglyceride levels and controls diabetes in patients with rare fat disorders known as lipodystrophies, according to researchers at UT Southwestern Medical Center at Dallas and the National Institute of Diabetes and Digestive and Kidney Diseases.

Released: 7-Mar-2002 12:00 AM EST
Bacteria's Iron-Absorbing Mechanisms May Open Gates for New Types of Antibiotics
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have brought to light new information about how bacteria capture iron from the human body, and the work has implications for the design of novel antibiotics.

5-Mar-2002 12:00 AM EST
Mechanism by Which Cocaine Elevates Blood Pressure
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have identified the underlying mechanism by which cocaine triggers hypertensive crisis, the most severe form of high blood pressure and one of the most common cocaine-related, cardiovascular emergencies in the United States.

Released: 25-Feb-2002 12:00 AM EST
Asthma and Pneumonia Linked
UT Southwestern Medical Center

Long-term infection with a bacteria that causes pneumonia could lead to chronic asthma, UT Southwestern Medical Center at Dallas researchers report.

Released: 6-Feb-2002 12:00 AM EST
Nutrition Guidelines for Diabetics Emphasize High-Monounsaturated Fat Diet
UT Southwestern Medical Center

Diabetics are no longer limited to a high-carbohydrate/low-fat diet, according to the latest guidelines issued by the American Diabetes Association. While that is still considered a healthy diet, they may now choose a high-monounsaturated diet instead.

Released: 26-Jan-2002 12:00 AM EST
$1.7M to Study Exercise Therapy to Minimize Effects of Aging, Treat Heart Failure
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have received a $1.7M grant from the National Institutes of Health to study the effects of aging on the heart and to determine if an endurance exercise-training program can prevent or treat congestive heart failure in the elderly.

26-Jan-2002 12:00 AM EST
Roehrborn Named UT Southwestern Urology Chairman
UT Southwestern Medical Center

Dr. Claus Roehrborn, the newly appointed chairman of urology at UT Southwestern Medical Center at Dallas, foresees enormous opportunities for the Department of Urology.

Released: 17-Jan-2002 12:00 AM EST
Closer to Defining Function of Two Proteins Involved in Neurotransmitter Release
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas are a step closer to defining the function of two proteins involved in neurotransmitter release, which initiates communication between neurons in the brain.

Released: 16-Jan-2002 12:00 AM EST
Mechanism Involved in Loss of Consciousness After Space Flight Pinpointed
UT Southwestern Medical Center

In one of the most ambitious medical experiments ever conducted aboard a space shuttle, UT Southwestern Medical Center at Dallas space researchers have pinpointed the mechanism responsible for the brief loss of consciousness and lightheadedness that many astronauts experience in the upright posture after space flight. The findings have broad application to medicine, both in space and on earth.

6-Jan-2002 12:00 AM EST
New Contact-Lens Materials Will Revolutionize the Industry
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas report that contact lenses, both rigid and soft, made from new hyper-oxygen transmissible materials are expected to reduce the possibility of bacterial infection better than contact lenses currently on the market. Based in part on these findings, the Food and Drug Administration recently approved hyper-oxygen transmissible contact lenses for 30-day continuous wear.

Released: 29-Dec-2001 12:00 AM EST
New Method of Delivering Vaccines
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have developed a quicker, more cost-efficient method of delivering dendritic cell-based vaccines -- a discovery that moves anti-tumor vaccines closer to a practical reality.

Released: 28-Dec-2001 12:00 AM EST
World-renowned neurobiologist joins UT Southwestern
UT Southwestern Medical Center

Dr. William Maxwell Cowan, former chief scientific officer of the Howard Hughes Medical Institute and a world-renowned neurobiologist known for research on brain function, has joined the UT Southwestern Medical Center at Dallas faculty.

20-Dec-2001 12:00 AM EST
Structures of Protein Molecules That Enable Two-Way Signaling Between Cells
UT Southwestern Medical Center

Two neuroscientists from UT Southwestern Medical Center at Dallas collaborated with cancer investigators in New York and Australia to determine the structures of protein molecules that bind together to initiate two-way signaling between human cells.

Released: 18-Dec-2001 12:00 AM EST
Acupuncture for Treatment of Patients with Bipolar Disorder
UT Southwestern Medical Center

Dr. Tricia Suppes has long been concerned about the 1.9 million Americans with bipolar disorder, also known as manic-depressive illness. That's why she's investigating a new use for an old therapy: acupuncture.

Released: 13-Dec-2001 12:00 AM EST
Statin Drugs Reduce Another Marker of Coronary-Artery Disease
UT Southwestern Medical Center

Two out of three statins, powerful drugs lauded for dramatically lowering low-density lipoproteins (LDL) - the bad cholesterol - have been found to significantly decrease another risk factor for coronary-artery disease, researchers at UT Southwestern Medical Center at Dallas reported.

6-Dec-2001 12:00 AM EST
Children's Cancer Fund Brings World-Class Pediatric Cancer Specialist to Dallas
UT Southwestern Medical Center

The Children's Cancer Fund of Dallas, now in its 19th year of supporting laboratory and clinical research, has helped bring one of the world's most promising young pediatric hematologist/oncologists to UT Southwestern Medical Center at Dallas.

Released: 4-Dec-2001 12:00 AM EST
Automated External Defibrillators to Become as Widespread as Fire Extinguishers
UT Southwestern Medical Center

Automated external defibrillators, portable 4-pound devices used to restore cardiac activity after sudden cardiac arrest, have the potential to save as many as 50,000 lives yearly and are expected to become as widespread as fire extinguishers, say researchers from UT Southwestern Medical Center at Dallas.

Released: 1-Dec-2001 12:00 AM EST
UT Southwestern Names New Chairman of Anesthesiology and Pain Management
UT Southwestern Medical Center

Dr. William E. Johnston, former chief of cardiothoracic anesthesiology at UT Medical Branch in Galveston, has been named chairman of anesthesiology and pain management at UT Southwestern Medical Center at Dallas.

1-Dec-2001 12:00 AM EST
Research Projects Bolstered with $3.6M in Funding
UT Southwestern Medical Center

The Texas Higher Education Coordinating Board has approved grants totaling $3.6M -- more than any other medical center in the state -- to fund 19 research projects at UT Southwestern Medical Center at Dallas. More than $61M in grants was distributed to Texas universities under the state-funded 2001 Advanced Research Program and Advanced Technology Program.

Released: 16-Nov-2001 12:00 AM EST
Better Gene Therapies for Immune-System Disease
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas and the Baylor Institute for Immunology Research in Dallas have linked abnormal secretion of alpha interferon to the malfunctioning immune systems of young patients with lupus, a disease that can damage kidneys, skin, heart and other organs in children and can be fatal without early treatment.

Released: 2-Nov-2001 12:00 AM EST
Experts Lead Forum to Offer Facts About Bioterrorism
UT Southwestern Medical Center

In the wake of the Sept. 11 attack and daily reports of anthrax exposures, UT Southwestern officials convened a panel of experts to discuss bioterrorism - the psychology of a terrorist, how to recognize and respond to a bioterrorist attack, and UT Southwestern's innovative research approaches to counteract bioterrorism.

Released: 2-Nov-2001 12:00 AM EST
Cellular Mechanisms Critical for Restoring Brain Functions After Traumatic Injuries
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have begun to reveal the cellular mechanisms critical for restoring brain functions after traumatic injuries - a step that could lead to effective treatments of paralysis and other brain and spinal-cord damage.

25-Oct-2001 12:00 AM EDT
$1.7M Grant to Study Effects of Long-Term Space Travel on the Heart
UT Southwestern Medical Center

Space researchers at UT Southwestern have received a $1.7M grant from the National Aeronautics and Space Administration to study why the heart decreases in size during long-term space travel.

Released: 24-Oct-2001 12:00 AM EDT
Sustained-Release Fluoride Significantly Reduces Risk of Vertebral Fractures
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have found that using sustained-release sodium fluoride with calcium citrate and vitamin D safely reduces the risk for vertebral fractures while increasing spinal bone mass in older women with osteoporosis.

Released: 18-Oct-2001 12:00 AM EDT
Gynecological Cancer Specialists Treat Patients Through New Hereditary Cancer Clinic
UT Southwestern Medical Center

The Department of Obstetrics and Gynecology at UT Southwestern Medical Center at Dallas has developed a gynecological cancer genetics clinic in conjunction with the medical center's Harold C. Simmons Comprehensive Cancer Center. Recently, it had also begun to serve community patients at Parkland.

Released: 18-Oct-2001 12:00 AM EDT
Volunteer Joins Search for Test to Detect Ovarian Cancer
UT Southwestern Medical Center

Marysol Rojas' mission is to teach women to talk with each other about cancer, especially cancer that attacks their ovaries, the deadliest women's cancer. That's why she volunteered for a study at UT Southwestern Medical Center at Dallas, where researchers are developing a test for ovarian cancer.

Released: 16-Oct-2001 12:00 AM EDT
Two Scientists Elected to National Academy of Sciences' Institute of Medicine
UT Southwestern Medical Center

Dr. Norman F. Gant Jr., professor of obstetrics and gynecology, and Dr. Eric Olson, chairman of molecular biology, have been elected to the Institute of Medicine, a component of the National Academy of Sciences.

Released: 4-Oct-2001 12:00 AM EDT
Cardiac Hormone Level Indicates Increased Risk of Death, Progression of Heart Failure
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have found that elevated levels of a cardiac hormone is predictive of an increased risk of death or heart failure in patients with complications of coronary artery disease.

3-Oct-2001 12:00 AM EDT
Radiofrequency Ablation to Destroy Kidney Tumors without Surgery
UT Southwestern Medical Center

Doctors at UT Southwestern killed a tumor on one of a patients kidneys with radiofrequency ablation, which involved only a needle and a CAT scan. After a one-hour procedure at Zale Lipshy University Hospital, the patient was back home, cancer-free.

Released: 29-Sep-2001 12:00 AM EDT
Alarming Number of Undiagnosed Hypertension, Diabetes
UT Southwestern Medical Center

A landmark heart disease study at UT Southwestern Medical Center, which will continue for at least seven more months, has already identified a large number of study participants who have undiagnosed high blood pressure or diabetes.

18-Sep-2001 12:00 AM EDT
Exercise Reverses Decline in Physical Conditioning Associated with Aging
UT Southwestern Medical Center

Six months of exercise can reverse the decline in physical conditioning associated with aging, researchers at UT Southwestern Medical Center at Dallas reported in a 30-year follow-up to the 1966 landmark Dallas Bed Rest and Training Study.

Released: 14-Sep-2001 12:00 AM EDT
How Neurons Communicate to Wire Developing Brain
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have discovered a biochemical pathway that helps describe how neurons in the brain and spinal cord form their connections. Further study into the new data could lead to discoveries in nerve regrowth and regeneration.

Released: 11-Sep-2001 12:00 AM EDT
UT Southwestern to Get Powerful Electron Microscope
UT Southwestern Medical Center

To focus at the molecular-level on the mechanics of human cells with a clarity rarely possible, UT Southwestern Medical Center at Dallas will install a $1.6 million state-of-the-art electron microscope and related equipment, officials said today.

7-Sep-2001 12:00 AM EDT
Amphetamines Paired with Therapy May Relieve Stroke-Related Speech Problems
UT Southwestern Medical Center

Stroke patients who take an amphetamine before speech-language therapy regain their speech at a faster rate than patients who go through speech-language therapy without the drugs, UT Southwestern Medical Center at Dallas researchers report.

7-Sep-2001 12:00 AM EDT
Hemophiliacs Run High Risk of Blood Clots from Implanted Catheters
UT Southwestern Medical Center

Despite hemophilia's persistent threat of prolonged bleeding, children with the disease run a high risk of developing dangerous internal blood clots from long-term central venous catheter implants, according to research at UT Southwestern Medical Center at Dallas.

23-Aug-2001 12:00 AM EDT
Physical Examination Important in Predicting Heart Failure Outcomes
UT Southwestern Medical Center

Two common findings from a traditional physical examination can provide important information for the 5 million Americans diagnosed with heart failure, according to researchers at UT Southwestern Medical Center at Dallas.

Released: 17-Aug-2001 12:00 AM EDT
Do-It-Yourself Tooth Bleaching Kits May Cause Problems
UT Southwestern Medical Center

People who want to brighten their smiles are opting for over-the-counter bleaching kits instead of visiting their dentist's office. While generally safe, these products have the potential to cause an infection or nerve damage, say UT Southwestern Medical Center at Dallas oral surgeons.

Released: 17-Aug-2001 12:00 AM EDT
Link Between Gene in Rare Disorder and Growth Factor
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas in collaboration with scientists at the University of Helsinki, Finland, have discovered a previously unknown connection between Lkb1, a tumor-suppressor gene associated with a rare genetic disorder called Peutz-Jeghers syndrome, and vascular endothelial growth factor (VEGF), a key regulator of blood vessels.

Released: 2-Aug-2001 12:00 AM EDT
Cocaine-Related Deaths, Drug-Related Emergency Visits Increasing
UT Southwestern Medical Center

Physicians should consider the possibility of cocaine use as a culprit when young adults are brought to emergency rooms for nontraumatic chest pains, according to researchers at the UT Southwestern Medical Center at Dallas.

Released: 31-Jul-2001 12:00 AM EDT
Key Protein in Transforming Excess Glucose Into Fat Isolated
UT Southwestern Medical Center

A biochemistry team from the Department of Veterans Affairs and UT Southwestern Medical Center at Dallas has identified a glucose-sensitive protein that translates excessively high-carbohydrate intake into body fat, especially when combined with a sedentary lifestyle.

19-Jun-2001 12:00 AM EDT
Replacing Estrogen by Skin Patches
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas report that administering replacement estrogen via a skin patch is superior to oral estrogen replacement therapy in lowering blood pressure and sympathetic nerve activity - the neural control of blood pressure - in postmenopausal women.

Released: 12-Jul-2001 12:00 AM EDT
New Liposuction Device Speeds Recovery
UT Southwestern Medical Center

A new liposuction device that varies the amount of ultrasound used is enabling UT Southwestern Medical Center at Dallas plastic surgeons to help patients recover with less bruising and discomfort than traditional ultrasound-assisted liposuction.

29-Jun-2001 12:00 AM EDT
Protein Essential to Development of Heart Discovered
UT Southwestern Medical Center

UT Southwestern Medical Center at Dallas researchers have found a protein that controls the development of the heart - a discovery that could contribute to novel methods of creating heart cells which could be used in the treatment of various cardiac conditions.

Released: 15-Jun-2001 12:00 AM EDT
Another Clue to Secrets of Cellular Aging
UT Southwestern Medical Center

UT Southwestern Medical Center at Dallas scientists discovered that genes near human telomeres can be silenced. This may help explain how and why humans age.

Released: 2-Jun-2001 12:00 AM EDT
Tumor-Suppressor Genes Linked to Insulin Signaling
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have discovered a link between insulin signaling and certain tumor-suppressor genes that may lead to significant progress in diabetes and cancer research.

Released: 1-Jun-2001 12:00 AM EDT
Labor Induction in Overdue Pregnancies Does Not Lead to More Caesarean Sections
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have shown that labor induction alone does not increase the probability of Caesarean section in pregnant women who exceed their due date.



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