A promising beta-blocker did not prolong survival of patients with advanced heart failure, according to a study conducted by researchers at UT Southwestern Medical Center at Dallas.
A panel of the nation's top cholesterol experts convened by the National Heart, Lung and Blood Institute has issued new guidelines focusing on preventing coronary heart disease, which is expected to lead to more than 35 million Americans, three times as many as currently, taking cholesterol-lowering medication and more than 65 million following a new recommended diet.
Many Americans suffer heartburn, but for some it's more frequent and serious. A new study by a UT Southwestern Medical Center at Dallas physician, published in today's Journal of the American Medical Association, suggests that anti-reflux surgery is no better for treating severe heartburn than antacid medications.
The beta-blocking drug carvedilol reduces the risk of death and the symptoms of mild to moderate heart failure in black patients as well as it does in nonblack patients, according to results from the U.S. Carvedilol Heart Failure Trials Program led by a researcher at UT Southwestern Medical Center at Dallas.
Under certain circumstances pediatric cancer patients recovering from chemotherapy can be treated as successfully as outpatients as they would be if hospitalized, UT Southwestern Medical Center at Dallas researchers report.
Researchers at UT Southwestern Medical Center at Dallas have located the gene that, when mutated, is responsible for autosomal recessive hypercholesterolemia, an inherited form of high cholesterol characterized by low-density lipoprotein levels of 350 to 600 milligrams per deciliter.
Cigarette smoking, especially in young women, can cause brain aneurysms and most patients don't know of the danger.
Getting a tattoo could be a key infection route for hepatitis C, the most common chronic viral infection affecting almost 2 percent of the United States population, according to a study by a UT Southwestern Medical Center at Dallas researcher.
The next major project for the National Aeronautics and Space Administration is the Mission to Mars.
Researchers at UT Southwestern Medical Center at Dallas and Rockefeller University have uncovered new information about dopamine-related activity in the brain that may lead to better understanding of the long-term brain-cell changes associated with cocaine addiction and addiction recovery. (Nature, 3-14-01)
The over-expression of a protein produced naturally in the human body inhibits cardiac hypertrophy and ultimately heart failure in transgenic mice, according to a study conducted by researchers at UT Southwestern Medical Center at Dallas.
UT Southwestern Medical Center at Dallas will be the site of the new National Training Program for the Comprehensive Care of Individuals With Multiple Sclerosis funded by the U.S. Congress.
Physiology researchers at UT Southwestern Medical Center at Dallas, working with Korean researchers, have connected defects in the transport of bicarbonate with cystic fibrosis. Their findings raise the question about whether delivering bicarbonate to diseased tissues can someday be used to lessen the effects of cystic fibrosis in patients and even extend their lives. (Nature, 3-1-01)
Researchers at UT Southwestern Medical Center at Dallas have reaffirmed the value of the nearly 50-year-old Apgar score as a quick and easy predictor of 28-day neonatal survival.
Knowledge gained from the human genome-mapping project already is leading to a better understanding of how drugs and alcohol act on the molecular and cellular mechanisms and brain pathways to cause addiction, a UT Southwestern Medical Center at Dallas researcher and his colleague say. (Nature, 2-12-01)
The Center for Biomedical Inventions at UT Southwestern Medical Center at Dallas has launched its first technology partnership, marking a milestone in the center's efforts to help build a biomedical industry in North Texas.
A UT Southwestern Medical Center at Dallas researcher has found that mutated mice bred without an essential protein exhibit symptoms of a rare disorder that causes involuntary "mirror movement" in people. (Neuron, 1-01)
Substituting margarine for butter reduces "bad" cholesterol - called low-density lipoproteins (LDL) - in adults and children, according to researchers at UT Southwestern Medical Center at Dallas. (JAMA, 12-5-00)
A UT Southwestern Medical Center at Dallas doctor is performing a new procedure that can detect pre-malignant and malignant breast cells long before they become visible tumors.
Individualized medical treatments for people diagnosed with heart disease may not be too far in the future with the expansion of genomic research at the University of Texas Southwestern Medical Center at Dallas. The expansion is being made possible by a $13.9 million federal grant.
Researchers at UT Southwestern Medical Center in Dallas have found that a device which can be used by airline flight crews can save the lives of sudden cardiac arrest victims aboard aircraft as well as be used for monitoring patients. (New England Journal of Medicine, 10-24-00)
Providing high-risk infants with more comprehensive follow-up care not only results in substantially healthier babies, but also saves money, according to a study by a UT Southwestern Medical Center at Dallas physician. (Journal of the American Medical Association, 10-25-00)
Researchers at UT Southwestern Medical Center at Dallas have found that a high intake of the antioxidant vitamin E reduces levels of a predictor of cardiovascular disease called C-reactive protein, or CRP.
Secure Internet sites could become an important tool for medical research, according to an article by two UT Southwestern Medical Center at Dallas physicians. (JAMA, 10-11-00)
A UT Southwestern Medical Center study proves that a recently developed fluid-based Pap test offers a relatively simple way for molecular changes in cell samples to be analyzed. This process could lead to the development of biomarkers identifying women at risk for cervical cancer. (Obstetrics and Gynecology, 9-11-00)
The NIH has awarded a $4.6 million, five-year grant that will allow UT Southwestern Medical Center at Dallas technology researchers and biologists to work together to develop new therapies for type II diabetes mellitus.
A strong link between brain cell loss on the left side of the brain has been found in sick Gulf War veterans and abnormal over-production of dopamine, a neurotransmitter chemical important in such conditions as degenerative brain diseases (Journal of Radiology, 6-00).
Researchers at UT Southwestern Medical Center have discovered that the protein SMAC may lead to the development of drugs that eliminate cancerous cells. The protein, second mitochondria-derived activator of caspases, promotes apoptosis, or cell death (Nature, 8-24-00).
Eric J. Nestler has been appointed chairman of psychiatry at UT Southwestern. Formerly director of molecular psychiatry at Yale University School of Medicine, his basic-science focus brings an added dimension to the Department of Psychiatry.
Nobel laureate Dr. Alfred Gilman, chairman of pharmacology at UT Southwestern Medical Center at Dallas, will lead a $10 million-per-year project allowing researchers around the world to pool their efforts in studying one of the biggest unsolved problems in biomedicine -- how cells interact with, or signal, each other.
Researchers at UT Southwestern Medical Center at Dallas have uncovered a potential explanation for how cyclosporine and related anti-rejection drugs can elevate blood pressure and cause hypertension in organ-transplant recipients.
A new way to deliver a schizophrenia drug that may help curtail the problem of patients not taking their medication, which is common in people with schizophrenia, is being tested by UT Southwestern Medical Center psychiatry researchers.
LASIK surgery is far better at correcting farsightedness than photorefractive keratectomy, ophthalmologists at UT Southwestern Medical Center at Dallas have discovered (Transactions of the American Ophthalmological Society).
A high intake of vitamin E can help reduce heart disease and stroke risk in type II diabetics, UT Southwestern researchers have found (Circulation, 7-11-00).
Brain scans of veterans who returned from the Gulf War sick show evidence of significant brain-cell loss, according to UT Southwestern Medical Center researchers.
UT Southwestern Medical Center researchers have developed an easy, inexpensive index to measure the severity of Alzheimer's disease (Journal of Neurology, 5-24-00).
In a national study of 681 chronically depressed patients, psychotherapy combined with the antidepressant Serzone improved mood in 85 percent of patients after only three months of treatment, reported a research team, which included UT Southwestern Medical Center, in NEJM (5-18-00).
A very high intake of dietary fiber, mostly from fruits and vegetables, lowers blood glucose levels in diabetics, shows a study by UT Southwestern Medical Center researchers (NEJM, 5-11-00).
A number of incontinent women diagnosed with overactive bladder may have bladder obstructions their doctors miss, a study by UT Southwestern Medical Center urologists showed (Journal of Urology, 6-00).
UT Southwestern Allied Health Sciences School is collaborating with the University of Arkansas for Medical Sciences to support online instruction for students interested in earning a bachelor's degree in nuclear medicine technology.
An NIMH $1.6 million grant will fund a research project, led by an associate professor of psychiatry at UT Southwestern Medical Center at Dallas, which will involve seriously depressed patients who have suffered at least two major depressive episodes during their lives.
In medical tests analyzing brain function, Gulf War veterans who complain of dizziness showed results similar to those of victims of the Toyko subway nerve gas attack, according to a University of Texas Southwestern Medical Center study (Otolaryngology-Head and Neck Surgery, 3-00).
A resurgence in interest in the high-protein, low-carbohydrate diet has prompted UT Southwestern Medical Center doctors to zero in on the fad diet to see if it increases the risk of kidney stones and loss of bone.
Sedentary white rabbits have given UT Southwestern Medical Center researchers a glimpse of the molecular changes that alter the structure and function of muscles following exercise training (Applied Physiology, 3-00).
Myogen and UT Southwestern Medical Center have announced a new patent and technology-licensing agreement and the establishment of collaborative research programs targeted at developing drugs to treat heart failure.
An innovative method of physical therapy in use at the University of Texas Southwestern Medical Center is helping some disabled individuals trade in their wheelchairs for walkers.
A study of genetically obese rats has revealed that an overabundance of fat can collect in heart cells and cause them to die, UT Southwestern Medical Center researchers report (Proceedings of the National Academy of Sciences, 2-14-00).
The higher a man's prostate specific antigen level is, the more likely his prostate will continue to grow abnormally, report UT Southwestern Medical Center researchers (Journal of Urology, 1-00).
By studying the crystal structure of a protein molecule, UT Southwestern Medical Center scientists have discovered an important cell-regulation process that impacts cancer development and may lead to the development of cancer-fighting drugs(Science, 12-99).
A new $4 million grant will allow UT Southwestern Medical Center at Dallas researchers to offer the latest and most advanced treatments under investigation to people infected with human immunodeficiency virus (HIV), the virus that causes AIDS.
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