St. Jude Children's Research Hospital
Memphis, TN USA

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Inherited Gene Variation Helps Explain Drug Toxicity in Patients of East Asian Ancestry


About 10 percent of young leukemia patients of East Asian ancestry inherit a gene variation that is associated with reduced tolerance of a drug that is indispensable for curing acute lymphoblastic leukemia (ALL), the most common childhood cancer....
26-Jan-2015 6:00 PM EST

Tumor Suppressor Protein Plays Key Role in Maintaining Immune Balance


St. Jude Children’s Research Hospital scientists have discovered that a protein widely known for suppressing tumor formation also helps prevent autoimmune diseases and other problems by putting the brakes on the immune response. The research was...
15-Jan-2015 12:00 PM EST

Tracing Evolution of Chicken Flu Virus Yields Insight Into Origins of Deadly H7N9 Strain


An international research team has shown how changes in a flu virus that has plagued Chinese poultry farms for decades helped create the novel avian H7N9 influenza A virus that has sickened more than 375 people since 2013. The research appears in...
29-Dec-2014 2:00 PM EST

Cells Identified That Enhance Tumor Growth and Suppress Anti-Cancer Immune Attack

A study led by St. Jude Children’s Research Hospital scientists has identified the population of white blood cells that tumors use to enhance growth and suppress the disease-fighting immune system. The results, which appear in the December 18...
18-Dec-2014 5:00 PM EST

Youngest Bone Marrow Transplant Patients at Higher Risk of Cognitive Decline

St. Jude Children’s Research Hospital study identifies small group of patients at risk for intellectual decline after bone marrow transplantation; results set stage for new strategies to preserve IQ and fight cancer
11-Dec-2014 12:00 PM EST

Promising Compound Rapidly Eliminates Malaria Parasite


An international research collaborative has determined that a promising anti-malarial compound tricks the immune system to rapidly destroy red blood cells infected with the malaria parasite but leave healthy cells unharmed. St. Jude Children’s...
5-Dec-2014 1:00 PM EST

Survivors of Childhood Eye Cancer Experience Normal Cognitive Functioning as Adults


Most long-term survivors of retinoblastoma, particularly those who had been diagnosed with tumors by their first birthdays, have normal cognitive function as adults, according to a St. Jude Children’s Research Hospital study. The research, which...
24-Nov-2014 11:00 AM EST

Gene Therapy Provides Safe, Long-Term Relief for Patients with Severe Hemophilia B


Gene therapy developed at St. Jude Children’s Research Hospital, University College London (UCL) and the Royal Free Hospital has transformed life for men with a severe form of hemophilia B by providing a safe, reliable source of the blood clotting...
19-Nov-2014 7:45 PM EST

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