St. Jude Children's Research Hospital
Memphis, TN USA

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Sun Damage Causes Genetic Changes That Predispose Children and Adolescents to Melanoma


The St. Jude Children’s Research Hospital—Washington University Pediatric Cancer Genome Project found that melanoma in some adolescent and adult patients involves many of the same genetic alterations and would likely respond to the same therapy....
4-Mar-2015 2:05 PM EST

Inherited Gene Variation Leaves Young Leukemia Patients at Risk for Peripheral Neuropathy


Researchers have identified the first genetic variation that is associated with increased risk and severity of peripheral neuropathy following treatment with a widely used anti-cancer drug. Investigators also found evidence of how it may be possible...
24-Feb-2015 11:00 AM EST

Possible Strategy Identified to Combat Major Parasitic Tropical Disease


Research led by St. Jude Children’s Research Hospital scientists has identified a potential target in the quest to develop a more effective treatment for leishmaniasis, a parasitic tropical disease that kills thousands and sickens more than 1...
18-Feb-2015 1:00 PM EST

Survivors of Childhood Cancer at Risk for Developing Hormone Deficiencies as Adults

Decades after undergoing cranial irradiation for childhood cancer, St. Jude Children’s Research Hospital investigators found that adult survivors of pediatric cancer remain at risk for pituitary hormone deficiencies that may diminish their health...
13-Feb-2015 11:00 AM EST

Inherited Gene Variations Tied to Treatment-Related Hearing Loss in Cancer Patients


St. Jude Children’s Research Hospital investigators have discovered inherited genetic variations that are associated with rapid hearing loss in young cancer patients treated with the drug cisplatin. The research appears in the current online issue...
9-Feb-2015 12:20 PM EST

Inherited Gene Variation Helps Explain Drug Toxicity in Patients of East Asian Ancestry


About 10 percent of young leukemia patients of East Asian ancestry inherit a gene variation that is associated with reduced tolerance of a drug that is indispensable for curing acute lymphoblastic leukemia (ALL), the most common childhood cancer....
26-Jan-2015 6:00 PM EST

Tumor Suppressor Protein Plays Key Role in Maintaining Immune Balance


St. Jude Children’s Research Hospital scientists have discovered that a protein widely known for suppressing tumor formation also helps prevent autoimmune diseases and other problems by putting the brakes on the immune response. The research was...
15-Jan-2015 12:00 PM EST

Tracing Evolution of Chicken Flu Virus Yields Insight Into Origins of Deadly H7N9 Strain


An international research team has shown how changes in a flu virus that has plagued Chinese poultry farms for decades helped create the novel avian H7N9 influenza A virus that has sickened more than 375 people since 2013. The research appears in...
29-Dec-2014 2:00 PM EST

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