St. Jude Children's Research Hospital
Memphis, TN USA

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Gene Sequencing Project Discovers Mutations Tied to Deadly Brain Tumors in Young Children

The St. Jude Children’s Research Hospital-Washington University Pediatric Cancer Genome Project has identified new mutations in pediatric brain tumors known as high-grade gliomas (HGGs), which most often occur in the youngest patients. The...
4/6/2014 1:00 PM EDT

Tumor Suppressor Gene TP53 Mutated in 90 Percent of Most Common Childhood Bone Tumor

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The St. Jude Children’s Research Hospital—Washington University Pediatric Cancer Genome Project found mutations in the tumor suppressor gene TP53 in 90 percent of osteosarcomas, suggesting the alteration plays a key role early in development of...
4/3/2014 12:00 PM EDT

Adult Cancer Drugs Show Promise Against an Aggressive Childhood Brain Tumor

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The quest to improve survival of children with a high-risk brain tumor has led St. Jude Children’s Research Hospital investigators to two drugs already used to treat adults with breast, pancreatic, lung and other cancers. The study was published...
3/27/2014 12:00 PM EDT

Health Gap Between Adult Survivors of Childhood Cancer and Siblings Widens with Age

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Adult survivors of childhood cancer face significant health problems as they age and are five times more likely than their siblings to develop new cancers, heart and other serious health conditions beyond the age of 35, according to the latest...
3/17/2014 4:00 PM EDT

Gene Sequencing Project Discovers Common Driver of a Childhood Brain Tumor

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The St. Jude Children’s Research Hospital-Washington University Pediatric Cancer Genome Project has identified the most common genetic alteration ever reported in the brain tumor ependymoma and evidence that the alteration drives tumor...
2/19/2014 1:00 PM EST

Researchers Discover Immune Signature That Predicts Poor Outcome in Influenza Patients

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St. Jude Children’s Research Hospital scientists have identified a signature immune response that might help doctors identify which newly diagnosed influenza patients are most likely to develop severe symptoms and suffer poor outcomes. The...
2/10/2014 12:20 PM EST

Mechanism Discovered for How Amyotrophic Lateral Sclerosis Mutations Damage Nerve Function

St. Jude Children’s Research Hospital scientists led a study showing that mutations in a gene responsible for amyotrophic lateral sclerosis (ALS) disrupt the RNA transport system in nerve cells. The findings appear in the current issue of the...
2/5/2014 12:00 PM EST

Promising Class of Antibiotics Discovered for Treatment of Drug-Resistant Tuberculosis

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St. Jude Children’s Research Hospital scientists have discovered a promising new class of antibiotics that could aid efforts to overcome drug-resistance in tuberculosis, a global killer.
1/27/2014 1:00 PM EST

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