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Newly Identified Pathway in Mitochondria Fuels Tumor Progression Across Cancer Types


Wistar Scientists identified a novel protein pathway across several types of cancer that controls how tumor cells acquire the energy necessary for movement, invasion and metastasis.
16-Dec-2016 10:05 AM EST Add to Favorites

The Wistar Institute Announces GSK Visiting Professor to Promote Academic-Industry Research Collaboration, Accelerate Drug Discovery


Wistar welcomes Kenneth W. Hance, Ph.D., M.P.H., Director of Antibody Therapies, Immuno-Oncology & Combinations DPU at GlaxoSmithKline (GSK), as its first Visiting Professor from GSK at Wistar.
15-Dec-2016 9:00 AM EST Add to Favorites

The Wistar Institute Awarded Nearly $9 Million to Advance Synthetic DNA Antibody-Based Therapy to Protect Against Zika Virus


The Bill & Melinda Gates Foundation has awarded an $8,777,578 million grant to The Wistar Institute to create a preventative Zika therapy utilizing synthetic DNA monoclonal antibodies (dMAbs).
30-Nov-2016 12:00 PM EST Add to Favorites

The Wistar Institute and Man’s Best Friend Therapeutics Announce Partnership to Advance Canine Melanoma Cancer Vaccine


The Wistar Institute and Man’s Best Friend Therapeutics are pleased to announce a new collaboration that leverages Wistar’s groundbreaking vaccine research and development with MBFT’s expertise in developing animal health products.
17-Nov-2016 11:05 AM EST Add to Favorites

DNA-Based Zika Vaccine Showed Protection From Infection, Brain Damage and Death

In this preclinical study, 100 percent of the animal models were protected from Zika after vaccination followed by a challenge with the Zika virus. In addition, they were protected from degeneration in the cerebral cortex and hippocampal areas of...
7-Nov-2016 2:00 PM EST Add to Favorites

Key Protein in Prostate Cancer Energy Production Identified

Scientists at The Wistar Institute have demonstrated how a protein called TRAP1 – an important regulator of energy production in healthy and cancerous cells – is an important driver of prostate cancer and appears to be a valuable therapeutic...
9-Nov-2016 4:00 PM EST Add to Favorites

Key Protein Implicated in Negative Side Effects of Senescence

Researchers at The Wistar Institute have identified a protein that plays a critical role in the expression of cytokines and chemokines, and that decreasing this protein suppresses the expression of these secreted factors. This suggests that there...
27-Oct-2016 2:00 PM EDT Add to Favorites

Estrogen Signaling Impacted Immune Response in Cancer


New research from The Wistar Institute showed that estrogen signaling was responsible for immunosuppressive effects in the tumor microenvironment across cancer types. These findings pave the way for combining immunotherapeutic treatments with...
17-Oct-2016 10:30 AM EDT Add to Favorites

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