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Released: 3-Aug-2009 8:00 AM EDT
Tiny Cup Attached to Eye Improves Drug Delivery for Retinal Diseases
Children's Hospital Los Angeles

A new drug delivery system that uses a tiny silicone cup sealed to the outer surface (episclera) of the eyeball may offer a more effective method for the delivery of medicines for retinal and vitreous diseases. The device, called an episcleral drug reservoir, holds the potential to fundamentally change the delivery of medications for diseases like macular degeneration, diabetic retinopathy, uveitis and retinoblastoma.

Released: 2-Nov-2009 3:00 PM EST
Red Reflex Vision Exam Should Be Given to All Newborns, Report Recommends
Children's Hospital Los Angeles

With the number of premature births and medically fragile infants now increasing in the U.S., a basic eye exam, including a red reflex test, should be given to all children shortly after birth. Unfortunately, some 75 percent of all children under five in the U.S. have never had a comprehensive eye exam, notes Angela Buffenn, M.D., M.P.H., Director of the Orbit and Eye Movement Institute at The Vision Center of Childrens Hospital Los Angeles and co-author of the report.

5-Jan-2010 7:00 AM EST
Hand-Held SD-OCT Imaging Device Diagnoses Neonates with Progressive ROP Earlier, More Accurately
Children's Hospital Los Angeles

Using a hand-held spectral domain optical coherence tomography (SD-OCT) imaging device, researchers have obtained high-resolution retinal scans of premature infants with progressive retinopathy of prematurity (ROP), according to a report in this month’s Archives of Ophthalmology.

Released: 16-Apr-2010 9:00 AM EDT
Hand Held Imaging Device Provides Important Evidence in Diagnosis of Shaken Baby Syndrome
Children's Hospital Los Angeles

Ophthalmologists examining infants for possible Shaken Baby Syndrome found that a handheld Spectral Domain Optical Coherence Tomography (SD-OCT) device provided high-resolution images of the retina and the vitreoretinal interface in infants with SBS, reports a study in the current issue of Retina, The Journal of Retinal and Vitreous Diseases.

Released: 10-Jun-2010 9:00 AM EDT
Treatment with Naturally Occuring Protein Prevents and Reverses Brain Damage Caused by Meningitis
Children's Hospital Los Angeles

Studies suggest role for IL-10 in prevention and treatment of potentially devastating neurological disease in newborns.

Released: 9-Jul-2010 8:00 AM EDT
Physicians Study Beta-Natriuretic Peptide in Pediatric Trauma
Children's Hospital Los Angeles

Investigators at Childrens Hospital Los Angeles have found that unlike adults, levels of serum beta-natriuretic peptide (BNP) do not increase in pediatric trauma patients with serious head injuries.

Released: 30-Sep-2010 9:00 AM EDT
Researchers Discover Way to Overcome Radiation Resistance in Leukemia
Children's Hospital Los Angeles

Radiation-resistant leukemia cells can be killed by radiation after inhibition of a molecular target by a rationally-designed new drug.

Released: 18-Feb-2011 2:10 PM EST
Scientists Bioengineer a Protein to Fight Leukemia
Children's Hospital Los Angeles

Breakthrough discovery is first report of a recombinant human biotherapeutic active against leukemic stem cells.

Released: 4-Apr-2012 3:25 PM EDT
Investigators Discover Possible Treatment Option for Drug-Resistant ALL
Children's Hospital Los Angeles

“Trojan horse”- type therapy specifically targets ALL cancer cells.

Released: 23-Apr-2014 2:00 PM EDT
Pollutants from Coal-Burning Stoves Strongly Associated with Miscarriages in Mongolia
Children's Hospital Los Angeles

Burning coal for domestic heating may contribute to early fetal death according to a new study by experts from The Saban Research Institute of Children’s Hospital Los Angeles and Ulaanbaatar, Mongolia – the coldest capital city in the world.


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