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Newswise: New enzyme discovery is another leap towards beating plastic waste
18-Mar-2022 10:20 AM EDT
New enzyme discovery is another leap towards beating plastic waste
University of Portsmouth

Scientists who helped to pioneer the use of enzymes to eat plastic have taken an important next step in developing nature-based solutions to the global plastics crisis.

16-Mar-2022 2:15 PM EDT
New model predicts how geographic features influence evolutionary outcomes
Washington University in St. Louis

Biologists have developed a new method to measure the extent to which regional geographic features — including barriers between regions, like mountains or water — affect local rates of speciation, extinction and dispersal for species. As a test case, they successfully used their model to delineate the movement and diversification of neotropical anole lizards.

Released: 21-Mar-2022 2:45 PM EDT
Effects of a Nurse-Led Telehealth Self-care Promotion Program on the Quality of Life of Community-Dwelling Older Adults: Systematic Review and Meta-analysis
Journal of Medical Internet Research

In recent years, telehealth has become a common channel for health care professionals to use to promote health and provide distance care. COVID-19 has further fostered the widespread use of this new technology, which can ...

Released: 21-Mar-2022 2:45 PM EDT
Clinical Outcomes Among Working Adults Using the Health Integrator Smartphone App: Analyses of Prespecified Secondary Outcomes in a Randomized Controlled Trial
Journal of Medical Internet Research

There is a need to find new methods that can enhance the individuals’ engagement in self-care and increase compliance to a healthy lifestyle for the prevention of noncommunicable diseases and improved quality of life. M...

Released: 21-Mar-2022 2:30 PM EDT
Effect of Sleep Disturbance Symptoms on Treatment Outcome in Blended Cognitive Behavioral Therapy for Depression (E-COMPARED Study): Secondary Analysis
Journal of Medical Internet Research

Sleep disturbance symptoms are common in major depressive disorder (MDD) and have been found to hamper the treatment effect of conventional face-to-face psychological treatments such as cognitive behavioral therapy. To in...

Released: 21-Mar-2022 2:15 PM EDT
Demographic and Psychosocial Characteristics Associated With Use of a Prostate Cancer Survivorship Website: Implications From a Multisite Randomized Controlled Trial
Journal of Medical Internet Research

Many prostate cancer (PC) survivors experience disease and treatment-related symptomatology in both the physical and psychosocial domains. Although the benefits and barriers to using web-based resources for cancer patient...

Released: 21-Mar-2022 1:50 PM EDT
A whale’s tale: the story hidden in their mouths
University of New South Wales

Baleen plates –the signature bristle-like apparatus toothless whales use to feed – reveal how these large aquatic mammals adapt to environmental changes over time.

Released: 21-Mar-2022 1:25 PM EDT
Study finds that an information shock is needed to make firms understand that music is changing
Bocconi University

The music industry, in little more than twenty years, has gone through two technological shocks linked to digitization: first the advent of downloads, which have replaced physical supports, then that of streaming, with the passage from the possession of a content to the right of access to a catalog.

Newswise: Research finds neighborhood green space tied to lower health care costs
Released: 21-Mar-2022 1:20 PM EDT
Research finds neighborhood green space tied to lower health care costs
Clemson University

A Clemson University faculty member collaborating with researchers from Kaiser Permanente Northern California Division of Research, has found that nature’s benefits may include savings on health care costs. The research, published March 17, 2022 in Environment International, suggests health care systems may spend hundreds of dollars less per person per year on medical care for people living in neighborhoods with the most green space than they do on those living near the least trees, shrubs and grass.

Released: 21-Mar-2022 1:20 PM EDT
Kids with complex conditions often lack adequate in-network care
Ohio State University

Children with complex medical conditions, especially those who require behavioral health treatment, often have to go outside of their insurance plans’ provider networks for care, a new study has found. Almost one in five children with complex, chronic medical conditions such as cystic fibrosis and Type 1 diabetes, who also need behavioral health care, are seen by specialists who are out of network, found the new study, led by researchers at The Ohio State University.

Newswise: Competition among worm sperm speeds up evolution
Released: 21-Mar-2022 1:00 PM EDT
Competition among worm sperm speeds up evolution
University of Oregon

From elaborate dances to stunning plumage displays to dramatic head-butting, male animals have an array of ways to distinguish themselves from competitors while wooing a potential mate. But it’s not their only chance to prove their worthiness. Sexual selection can take place after mating, too, and new research from University of Oregon scientists suggests that it can have a surprisingly large impact on evolution.

Newswise: Booster for immune protection after Corona infection
Released: 21-Mar-2022 12:55 PM EDT
Booster for immune protection after Corona infection
Max Planck Institute of Molecular Physiology

Our immune protection is provided by two systems working hand in hand. When infected with a virus, the immune system reacts by producing antibodies that can prevent the virus from infecting further cells.

Newswise: Computational approach enables spatial mapping of single-cell data within tissues
18-Mar-2022 4:50 PM EDT
Computational approach enables spatial mapping of single-cell data within tissues
University of Texas MD Anderson Cancer Center

A new computational approach developed by researchers at The University of Texas MD Anderson Cancer Center successfully combines data from parallel gene-expression profiling methods to create spatial maps of a given tissue at single-cell resolution. The resulting maps can provide unique biological insights into the cancer microenvironment and many other tissue types.

17-Mar-2022 11:35 AM EDT
Axi-cel proves effective as first-line treatment for high-risk lymphoma
University of Texas MD Anderson Cancer Center

Results from the ZUMA-12 trial led by researchers at The University of Texas MD Anderson Cancer Center showed that first-line treatment with axicabtagene ciloleucel (axi-cel), a chimeric antigen receptor (CAR) T cell therapy, achieved a high rate of complete response in patients with high-risk large B-cell lymphoma (LBCL). The study was published today in Nature Medicine, and results recently were presented at the 2021 American Society of Hematology (ASH) meeting.

Released: 21-Mar-2022 11:50 AM EDT
A novel painless and reliable allergy test
University of Bern

Although allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not always clear.

Released: 21-Mar-2022 11:40 AM EDT
New Study Identifies Small Yet Essential Workforce Providing Abortions in the U.S.
George Washington University

Efforts to determine the actual size and makeup of the abortion provider workforce in the U.S. often rely on surveys that are limited in scope or else focus solely on abortion facilities. To get more comprehensive pictures of the abortion provider workforce, researchers at the George Washington University combed through a national medical claims data set to examine the workforce providing abortion care and management of pregnancy loss.

Newswise: Tiny magnets could hold the secret to new quantum computers
Released: 21-Mar-2022 11:35 AM EDT
Tiny magnets could hold the secret to new quantum computers
Argonne National Laboratory

Argonne scientists have discovered a type of magnetic behavior that could help enable magnetically based quantum devices.

Released: 21-Mar-2022 11:15 AM EDT
Classifying Weather to Tease Out How Aerosols Influence Storms
Brookhaven National Laboratory

Machine learning study tracks large-scale weather patterns, providing baseline categories for disentangling how aerosol particles affect storm severity.

Released: 21-Mar-2022 10:10 AM EDT
COVID-19 pandemic fueled massive growth in green industry
University of Georgia

Most people would say the COVID-19 pandemic hasn’t been a great couple of years. But for the green industry, like plant nurseries and greenhouses, it’s been a boon. But will the uptick in gardening last once the last coronavirus restrictions are lifted? Probably not to the same extreme levels, according to new research from the University of Georgia. But for some, the introduction to gardening may have been just what they needed to dive into a new hobby.

Newswise: Clinical study finds that offering digital health platform Cardihab increases participation in cardiac rehabilitation
Released: 21-Mar-2022 10:05 AM EDT
Clinical study finds that offering digital health platform Cardihab increases participation in cardiac rehabilitation
JMIR Publications

“Cardihab provides an important option to help overcome barriers to participation in conventional in-person cardiac rehabilitation programs. Patients do not have to travel long distances to attend a program – they complete it from home while under clinical supervision. Cardihab also helps fit in with peoples’ busy work schedules and family commitments, and alleviates cost and time constraints associated with traditional programs. It has been a critical alternative particularly during COVID-19 whereby significant disruptions to traditional programs have been experienced Australia wide, and social distancing requirements presented further barriers to participation.” [Ms Souris]

     
Released: 21-Mar-2022 9:00 AM EDT
New Joint ACG-CAG Guidelines on Management of Anticoagulants and Antiplatelets during Acute GI Bleeding and Periendoscopic Period
American College of Gastroenterology (ACG)

Evidence-based clinical guidelines on the management of patients on common anticoagulant and antiplatelet therapies during gastrointestinal (GI) bleeding or undergoing elective endoscopy have been published jointly by the American College of Gastroenterology (ACG) and the Canadian Association of Gastroenterology (CAG).

Released: 21-Mar-2022 8:05 AM EDT
New experiment could confirm the fifth element
University of Portsmouth

An experiment which could confirm the fifth state of matter in the universe - and change physics as we know it - has been published in a new paper from the University of Portsmouth.

Newswise: Collisions of “Isobars” Produce Surprising Result
Released: 21-Mar-2022 7:05 AM EDT
Collisions of “Isobars” Produce Surprising Result
Department of Energy, Office of Science

Scientists compared collisions of ruthenium-96 ions with collisions of zirconium-96 ions, which have four fewer protons, expecting to see a greater separation of charged particles emerging from ruthenium collisions because its greater proton number generates a stronger magnetic field. The results instead showed slightly more charge separation in zirconium collisions. This suggests there may be more differences between these two “isobar” nuclei than just their proton numbers.

Released: 21-Mar-2022 6:00 AM EDT
Cerebral Protection in TAVR—Can We Do Without? A Real-World All-Comer Intention-to-Treat Study—Impact on Stroke Rate, Length of Hospital Stay, and Twelve-Month Mortality
Journal of Personalized Medicine

… Although rates of clinically overt cerebrovascular events associated with TAVR are reported to be low—particularly in low-risk patients [26]—… on patient population, study design, and stroke definition. As we treat more and more patients with TAVR …

Released: 21-Mar-2022 6:00 AM EDT
Successful transfemoral-transcatheter aortic valve replacement in high-risk patients with a grade 4 atheroma in the ascending aorta: cerebral protection with a filter device
General Thoracic and Cardiovascular Surgery

… quite high risk of procedure-related stroke after TAVR due to the grade 4 thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …

Released: 21-Mar-2022 6:00 AM EDT
The Heart Brain Team and Patient-Centered Management of Ischemic Stroke
Journal of the American College of Cardiology

… What is the role of routine cerebral embolic protection (CEP) with TAVR? Do all TAVR strokes occur because of intraprocedural catheter manipulations (Figure 7)? Are there neurological sequalae to the use of the CEP themselves? Can CEP be …

Released: 21-Mar-2022 6:00 AM EDT
Delivery of Stem Cell Secretome for Therapeutic Applications
ACS Applied Bio Materials

Delivery of Stem Cell Secretome for Therapeutic Applications F Li, J Zhang, K Yi, H Wang, H Wei, HF Chan, Y Tao… - ACS Applied Bio Materials, 2022 … delivery of stem cell secretome deserve more attention. In this review, we first discuss approaches for the production and characterization of stem cell secretome and their optimization strategies. Moreover, the up-to-date studies to improve the … [HTML] Cancer Stem Cell Markers for Urinary Carcinoma P Xia, DH Liu, ZJ Xu, F Ren - Stem Cells International, 2022 … Cancer stem cell (CSC) refers to cancer cells with stem cell properties, that is, they have the ability of “self-renewal” and “differentiation.” … In this review, cancer stem cell surface markers and functional markers in urinary system were summarized …

Released: 21-Mar-2022 6:00 AM EDT
Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement
Journal of Clinical Medicine

… In contrast, incidence of postprocedural stroke was relatively low in our study (1.8%), and periprocedural AF was not associated with higher risk of stroke. Risk of stroke after TAVR can be affected by various factors, including antithrombotic regimens …

Newswise: Scientists uncover new targets for treating Parkinson's disease
18-Mar-2022 2:35 PM EDT
Scientists uncover new targets for treating Parkinson's disease
La Jolla Institute for Immunology

Scientists at La Jolla Institute for Immunology (LJI) have found that people with Parkinson's disease have a clear "genetic signature" of the disease in their memory T cells. The scientists hope that targeting these genes may open the door to new Parkinson's treatments and diagnostics.

Released: 21-Mar-2022 2:45 AM EDT
Exploring the Discursive Emphasis on Patients and Coaches Who Participated in Technology-Assisted Diabetes Self-management Education: Clinical Implementation Study of Health360x
Journal of Medical Internet Research

Background: A critical unmet need for underserved patients with diabetes is regular access to sufficient support for diabetes self-management. Although advances in digital technologies have made way for eHealth applications that prov...

Newswise: Rare genetic anomaly linked to 20% of childhood Acute Myeloid Leukemia cases
Released: 20-Mar-2022 10:05 PM EDT
Rare genetic anomaly linked to 20% of childhood Acute Myeloid Leukemia cases
University of South Australia

New genetic research from UniSA shows that up to 19 per cent of childhood AML cases are linked to rare genetic changes that may be inherited through family blood lines.

Released: 20-Mar-2022 12:00 PM EDT
ASD modelling in organoids reveals imbalance of excitatory cortical neuron subtypes during early neurogenesis
Preprints

There is no clear genetic etiology or convergent pathophysiology for autism spectrum disorders (ASD). Using induced pluripotent stem cell (iPSC)-derived brain organoids and single-cell transcriptomics, we modeled alterations in the formation of the forebrain between sons with ASD and their unaffected fathers in ten families. Relative to fathers, probands with macrocephaly presented an increase in dorsal cortical plate excitatory neurons (EN-DCP) to the detriment of preplate lineages, whereas normocephalic ASD probands presented an opposite decrease in EN-DCP-related gene expression. Both cohorts converged in a dysregulation of outer radial glia genes related to translation.

Released: 20-Mar-2022 11:05 AM EDT
First Look at Emerging Tobacco Industry Product Shows New Consumer Interest and Awareness
Rutgers University-New Brunswick

Consumer interest and awareness in nicotine pouches – products that contain nicotine but have no tobacco and one of the newest industry products — is growing and they are most popular among younger smokers and those trying to quit, according to a Rutgers research study.

   
16-Mar-2022 2:00 PM EDT
Drug combination shows effectiveness in endometrial cancer patients
Dana-Farber Cancer Institute

Letrozole and abemaciclib cause tumor shrinkage or stabilization in 75% of patients in phase 2 trial. Approximately 30% of trial participants had their tumors shrink by more than 30%

Newswise: UNLV Researchers Discover New Form of Ice
Released: 18-Mar-2022 5:05 PM EDT
UNLV Researchers Discover New Form of Ice
University of Nevada, Las Vegas (UNLV)

By incrementally raising the pressure in diamond anvil cell, and periodically blasting it with a laser beam, UNLV scientists observed a sample of water ice make the transition from a known cubic phase, Ice-VII, to a newly discovered intermediate phase, Ice-VIIt, before settling into another known phase, Ice-X.

Released: 18-Mar-2022 4:45 PM EDT
Astronomers Closer to Unlocking Origin of Mysterious Fast Radio Bursts
University of Nevada, Las Vegas (UNLV)

Nearly 15 years after the discovery of fast radio bursts (FRBs), the origin of the millisecond-long, deep-space cosmic explosions remains a mystery. That may soon change, thanks to the work of an international team of scientists – including UNLV astrophysicist Bing Zhang – which tracked hundreds of the bursts from five different sources and found clues in FRB polarization patterns that may reveal their origin.

Newswise: New strategy reduces brain damage in Alzheimer’s and related disorders, in mice
Released: 18-Mar-2022 3:25 PM EDT
New strategy reduces brain damage in Alzheimer’s and related disorders, in mice
Washington University in St. Louis

Alzheimer’s disease is the most common and best known of the tauopathies, a set of neurodegenerative brain diseases caused by toxic tangles of the protein tau. A study by researchers at Washington University School of Medicine in St. Louis has shown that targeting astrocytes — an inflammatory cell in the brain — reduces tau-related brain damage and inflammation in mice.

Newswise: Texas Biomed and partners discover new, potent COVID-19 antibody cocktail
Released: 18-Mar-2022 3:20 PM EDT
Texas Biomed and partners discover new, potent COVID-19 antibody cocktail
Texas Biomedical Research Institute

Researchers at Texas Biomed and University of Alabama at Birmingham discovered an antibody cocktail against COVID-19 that appears effective against all variants and other coronaviruses. The cocktail has been exclusively licensed to Aridis Pharmaceuticals, which is seeking a manufacturing partner to advance the treatment to human clinical trials.

Released: 18-Mar-2022 3:10 PM EDT
Language may not shape social outcomes
Cornell University

Does language shape thought? Do the languages we speak affect how we live our lives? These are some of the oldest questions in the cognitive and social sciences, and a handful of high-profile research articles in the social sciences have argued that language systematically affects people’s values, beliefs and behaviors.

Released: 18-Mar-2022 3:00 PM EDT
Tracking Subjective Sleep Quality and Mood With Mobile Sensing: Multiverse Study
Journal of Medical Internet Research

Background: Sleep influences moods and mood disorders. Existing methods for tracking the quality of people’s sleep are laborious and obtrusive. If a method were available that would allow effortless and unobtrusive tracking of slee...

Newswise: Artificial intelligence paves the way to discovering new rare-earth compounds
Released: 18-Mar-2022 2:45 PM EDT
Artificial intelligence paves the way to discovering new rare-earth compounds
Ames National Laboratory

Artificial intelligence advances how scientists explore materials. Researchers from Ames Laboratory and Texas A&M University trained a machine-learning (ML) model to assess the stability of rare-earth compounds. The framework they developed builds on current state-of-the-art methods for experimenting with compounds and understanding chemical instabilities.



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