Focus: Cancer Center Featured Story 2

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Moffitt’s Radiation Oncology Department will utilize Cvergenx’s Genomic-Adjusted Radiation Dose (GARD) model.

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As published in JNCCN – Journal of the National Comprehensive Cancer Network, researchers at UT Southwestern Medical Center found significant racial and gender-based disparities in outcomes among patients with locoregional anal cancer.

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For more than a decade, SCCA/UWMC consistently has maintained a top standing among the top hospitals for adult cancer care in the U.S.

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Dana-Farber /Brigham and Women's Cancer Center is ranked no. 4 in cancer by U.S. News and World Report.

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Roswell Park Cancer Institute has been named a 2017–18 Best Hospital for cancer by U.S. News & World Report. The Buffalo, N.Y., comprehensive cancer center was ranked by the news outlet as 33rd among nearly 900 cancer hospitals reviewed nationwide, and was also recognized as high-performing in urology and lung cancer surgery.

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The U.S. Food and Drug Administration has awarded orphan drug status to SurVaxM, a promising immunotherapy vaccine developed at Roswell Park Cancer Institute and being studied as a treatment for glioblastoma, a type of brain cancer.

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100 cancer centers throughout the country have pledged to adopt a life-saving administration policy for vincristine

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In an animal model of obesity and breast cancer, tumor cells in obese animals but not lean animals had especially sensitive androgen receptors, allowing these cells to magnify growth signals from the hormone testosterone.

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NCCN Foundation Young Investigator Awards provide funding over a two-year period for research initiatives focused on assessing and improving outcomes in cancer care.

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A Yale chemistry professor is closing in on a medical breakthrough that could help cure a rare genetic disorder as well as pioneer a novel way of treating disease.

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A collaboration between two laboratories – one in Engineering and the other in Medicine – has led to a promising drug delivery system that uses nanoparticles to fight a particularly aggressive and hard-to-treat brain cancer.

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The Dana-Farber Cancer Institute is pleased to announce the opening of the new Leonard P. Zakim Center for Integrative Therapies and Healthy Living, underscoring Dana-Farber’s commitment to providing cutting-edge patient therapies and support for the “whole person” during and after treatment. Increasing data has indicated that integrative therapies can help alleviate side effects of cancer therapy.

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Many are finding that aspirin can slow or prevent one of mankind's deadliest diseases: cancer. While the mechanism is still debated, some experts say aspirin reduces the inflammation that drives cancer.

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Young patients with a particular type of leukemia who have relapsed after going into remission may find new hope through a treatment that involves modifying a patient’s own T cells, an important part of the immune system, to destroy cancer cells.

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The University of Kansas Cancer Center announced today that the National Cancer Institute (NCI) renewed its national cancer center designation for five years and that Children’s Mercy has been formally approved as a cancer center consortium partner

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When Yale researchers took a closer look at skin cells, they discovered the unaffected neighbor cells are not helplessly awaiting invasion of cancer cells but acting like cellular police, actively correcting tissue flaws created by their aberrant neighbors, the investigators report Aug. 2 in the journal Nature.

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Precision medicine has become the leading innovation of cancer treatment. Patients are routinely treated with drugs that are designed to target specific tumors and molecules. Despite the progress that has been made in targeted cancer therapies, the path has been slow and scientists have a long road ahead. In a collaborative project, researchers at the Moffitt Cancer Center and Dana-Farber Cancer Institute investigated the emerging field of radiomics has the potential to improve precision medicine by non-invasively assessing the molecular and clinical characteristics of lung tumors. Their work was published in the July 21 issue of eLIFE, a novel, emerging journal in biomedicine founded by National Academy members and Nobel Prize winners.

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HHMI Investigator Arul Chinnaiyan is using comprehensive tumor sequencing to better capture the drivers of metastatic cancer and treat the disease more effectively.

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A collaborative campaign brings together the leading funder of immunotherapy research internationally with North America’s largest nonprofit dedicated to supporting Israeli cancer research

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The Helping to Enhance Research in Oncology program will hold its tenth annual celebration event. The event honors those on cancer clinical trials and raises awareness for the importance of cancer clinical trials. The event will offer public information sessions about clinical trials.

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Roswell Park Cancer Institute and the Mayo Clinic Cancer Center are jointly hosting the 10th annual Spirit of EAGLES: Changing Patterns of Cancer in Native Communities conference, to be held Sept. 21–24 in Niagara Falls, New York.

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Writing today in the journal Cancer Research, James DeGregori, PhD, deputy director of the University of Colorado Cancer Center offers evidence that it is forces of evolution driven by natural selection acting in the ecosystem of the body that, in the presence of tissue damage, allow cells with dangerous mutations to thrive.

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Quick summaries for journalists that offer sources and story ideas from Fred Hutch. Each links to more detailed information and includes contact information for arranging interviews. Topics include Glioblastoma, tumor microenvironment and more.

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The Lung Cancer Mutation Consortium at the University of Colorado Cancer Center reports this week in the journal Cancer that 24 of 920 patients (3 percent) with advanced-stage lung cancer had mutations in the gene HER2. Seventy-one percent of these patients were never-smokers, with a median age of 62. The gene HER2 has been known as a breast cancer driver, with therapies approved to target HER2 mutations in this setting.

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Rutgers Cancer Institute of New Jersey investigators have received $450,000 in funding to support research projects in immunotherapy and basic science research that could impact pancreatic, breast and other cancers. The Pre- and Post-Doctoral Fellowship Grants were awarded by the New Jersey Commission on Cancer Research.

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University of Colorado Cancer Center study published online ahead of print in the journal Oncogene offers compelling evidence explaining failure of retinoic acid trials against breast cancer and offers a possible strategy for their use.

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The University of New Mexico Comprehensive Cancer Center has received designation as a Myelodysplastic Syndromes Foundation Center of Excellence. The designation puts UNM Comprehensive Cancer Center on the MDS Foundation’s list of international sites to which people with blood disorders may go to receive treatment. Myelodysplastic syndromes result from failure of the bone marrow to produce blood cells.

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The Lobo Cancer Challenge is a new bike ride fundraising event. Event proceeds will help to ensure that all New Mexicans have access to outstanding cancer care and benefit from the latest cancer research. The ride will take place September 23, 2017.

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For patients with advanced, inoperable stage 3 lung cancer, concurrent chemotherapy and the specialized radiation treatment, proton therapy, offers improved survival compared to historical data for standard of care, according to a new study from The University of Texas MD Anderson Cancer Center.

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Breast Cancer Surveillance Consortium (BCSC) investigators have received a $17 million program project grant renewal from the National Cancer Institute to study the effectiveness of different breast cancer screening and surveillance strategies using digital mammography, digital breast tomosynthesis (3D mammography), and breast MRI. Co-led by UC Davis researcher Diana Miglioretti, the consortium seeks to ensure that women get personalized care based on their individual risk and preferences.

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Integration of NCCN clinical recommendations into ION Solutions’ IntelliDoseTxM system will provide oncologists access to evidence-based treatment decision support based on the NCCN Guidelines®.

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Researchers at Fred Hutchinson Cancer Research Center showed about 70 percent of patients with the most common adult leukemia had their tumors shrink or disappear following an experimental chimeric antigen receptor (CAR) T-cell immunotherapy. The researchers also found that measuring genetic traces of cancer cells taken from bone marrow biopsies might be a better indicator of prognosis than the standard lymph node scan.

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Ludwig researchers show how a method that physically expands tissues can improve early breast cancer diagnostics and extend the capabilities of ordinary pathology labs

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A key committee for the U.S. Food and Drug Administration issued a first-of-its-kind recommendation this week, unanimously signing off on an experimental cancer treatment

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Moffitt researchers launched a first of its kind study comparing the long-term benefits of radiation therapy in women with breast cancer either before surgery or after surgery. Their study found that patients who have neoadjuvant radiation therapy have a significantly lower risk of developing a second primary tumor at any site.

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A research team led by scientists at UC San Francisco has developed a computational method to systematically probe massive amounts of open-access data to discover new ways to use drugs, including some that have already been approved for other uses.

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Janet Gordils-Perez, DNP, RN, ANP-BC, AOCNP, from Plainsboro Township, has been named Chief Nursing Officer at Rutgers Cancer Institute of New Jersey. She was recently promoted from her position as Director of Oncology Nursing. Dr. Gordils-Perez came to Rutgers Cancer Institute in 2004 from Memorial Sloan-Kettering Cancer Center, where she was an adult nurse practitioner and a clinical research nurse.

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As published in JNCCN, a University of Michigan Comprehensive Cancer Center study found that adherence to distress screening protocols set by the Commission on Cancer could lead to 18% fewer ER visits and 19% fewer hospitalizations.

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Ursa Brown-Glaberman, MD, received the National Cancer Institute’s Cancer Clinical Investigator Team Leadership Award. The NCI award is given to outstanding cancer clinical investigators. Cancer clinical investigators conduct clinical trials to discover new or better ways to find, prevent and treat cancer.

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Immune cells with a general knack for recognizing and killing many types of infected or abnormal cells also can be engineered to hunt down cells with specific targets on them to treat cancer, researchers at The University of Texas MD Anderson Cancer Center report in the journal Leukemia

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The treatment of osteosarcoma, the most common tumor of bone, is challenging. A study led by The University of Texas MD Anderson Cancer Center found a drug known as bone metastasis-targeting peptidomimetic (BMTP-11) has potential as a new therapeutic strategy for this devastating illness.

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University of Colorado Cancer Center's Thomas Flaig, MD, has been named chair of the NCCN Clinical Practice Guidelines in Oncology Panel for Bladder Cancer, a group of 34 multidisciplinary bladder experts from NCCN Member Institutions that will influence the future direction of care for the disease.

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Three case reports published in the New England Journal of Medicine demonstrate the promise of cancer immunotherapy in gray zone lymphoma, potentially paving the way for clinical trials utilizing this strategy in this and related conditions.

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With its internationally renowned school of veterinary medicine and its NCI-designated comprehensive cancer center, UC Davis is uniquely positioned to harness the power of each to tackle one of life’s greatest challenges: cancer.

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University of Pennsylvania study reveals narrow network insurance plans cut out access to NCCN Member Institutions and other top comprehensive cancer centers throughout the United States

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Feeding pregnant female mice a diet high in fat derived from common corn oil resulted in genetic changes that substantially increased breast cancer susceptibility in three generations of female offspring, reports a team of researchers led by scientists at Georgetown Lombardi Comprehensive Cancer Center.

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Fred Hutchinson Cancer Research Center’s board of trustees yesterday elected three new members, adding expertise in information technology, media and global health as it works to accelerate efforts to develop cures for cancer and other diseases.

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$400k grant to Johns Hopkins University School of Medicine investigator Cynthia Sears will carry out research aimed at improving effectiveness of immunotherapy in patients with colorectal cancer.