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9-Sep-2011 8:00 AM EDT
Large Increase Seen in Number of Lymph Nodes Evaluated for Colon Cancer
JAMA - Journal of the American Medical Association

During the past two decades there has been a significant increase in the percentage of patients who have a high number of lymph nodes evaluated during colon cancer operations, but this improvement is not associated with an increase in the overall proportion of colon cancers that are node positive, according to a study in the September 14 issue of JAMA.

9-Sep-2011 8:00 AM EDT
Study Examines Risk of Aortic Complications Among Patients with Common Congenital Heart Valve Defect
JAMA - Journal of the American Medical Association

While the incidence of the life-threatening condition of aortic dissection is significantly higher than in the general population, it remains low among patients with the congenital heart defect, bicuspid aortic valve; however, the incidence of aortic aneurysms is significantly high, according to a study in the September 14 issue of JAMA.

9-Sep-2011 1:20 PM EDT
Stronger Teen Graduated Driver Licensing Programs Show Mixed Results for Involvement in Fatal Crashes
JAMA - Journal of the American Medical Association

The use of stronger graduated driver licensing programs for 16- to 19-year old drivers in the U.S. that included restrictions on nighttime driving and allowed passengers were associated with a lower incidence of fatal crashes among 16-year old drivers, but a higher incidence among 18-year olds, according to a study in the September 14 issue of JAMA.

12-Sep-2011 3:40 PM EDT
Study Links 23 MicroRNAs to Laryngeal Cancer
Henry Ford Health

A Henry Ford Hospital study has identified 23 microRNAs for laryngeal cancer, 15 of which had yet to be reported in head and neck cancer. The researchers say the discovery could yield new insight into what causes certain cells to grow and become cancerous tumors in the voice box.

9-Sep-2011 11:45 AM EDT
Unique Study Shows Efficacy of Imaging in Evaluating Heart Drug Dalcetrapib
Mount Sinai Health System

Researchers from Mount Sinai School of Medicine have for the first time used several imaging techniques to prove the efficacy of a promising new treatment for atherosclerosis—the build-up of plaque in artery walls that can lead to a heart attack.

6-Sep-2011 2:00 PM EDT
Study Reveals Link Between High Cholesterol and Alzheimer’s Disease
American Academy of Neurology (AAN)

People with high cholesterol may have a higher risk of developing Alzheimer’s disease, according to a study published in the September 13, 2011, issue of Neurology®, the medical journal of the American Academy of Neurology.

8-Sep-2011 2:00 PM EDT
Enzyme Might Be Target for Treating Smoking, Alcoholism at Same Time
University of California, San Francisco (UCSF)

An enzyme that appears to play a role in controlling the brain's response to nicotine and alcohol in mice might be a promising target for a drug that simultaneously would treat nicotine addiction and alcohol abuse in people, according to a study by researchers at the Ernest Gallo Clinic and Research Center, affiliated with the University of California, San Francisco.

8-Sep-2011 1:10 PM EDT
Mayo Clinic Creates Healthy Aging and Independent Living Lab
Mayo Clinic

The Mayo Clinic Center for Innovation (CFI) announced today that Best Buy® is the founding consortium member of a new “living lab” in the Charter House, a continuing care retirement community in Rochester. John Noseworthy, M.D., President and CEO of Mayo Clinic, made the announcement at the Transform 2011 symposium today.

7-Sep-2011 1:15 PM EDT
Researchers Discover Blood Proteins Associated with Early Development of Lung Cancer
Fred Hutchinson Cancer Center

A research team led by Fred Hutchinson Cancer Research Center has discovered proteins in the blood that are associated with early lung cancer development in mice and humans. The advance brings the reality of a blood test for the early detection and diagnosis of lung cancer a step closer.

31-Aug-2011 4:15 PM EDT
New Studies on Bacterial Biofilm May Open Door to Treating Sinusitis
NovaBay Pharmaceuticals

The latest evidence for NVC-422’s power against biofilms comes from a just-published study by researchers at the University of Adelaide in Australia. The study focused on sinusitis, an ailment marked by an inflammation of the paranasal sinuses, often as a consequence of a bacterial infection.

9-Sep-2011 5:00 PM EDT
Fast-Paced, Fantastical Television Shows May Compromise Learning, Behavior of Young Children
University of Virginia

Young children who watch fast-paced, fantastical television shows may become handicapped in their readiness for learning, according to a new University of Virginia study published in the October issue of the journal Pediatrics.

7-Sep-2011 2:40 PM EDT
Scientists Find Link Between Seizures and Brain Tumors
University of Alabama at Birmingham

New research from the University of Alabama at Birmingham pinpoints the relationship between primary brain tumors and the onset of epileptic seizures and reveals that a drug used to treat Crohn’s disease inhibits those seizures and may be able to slow a tumor’s growth. The onset of seizures is a common symptom in gliomas and often is the first sign of a brain tumor. Sen. Ted Kennedy had a seizure in May 2008, and three days later doctors confirmed that he had a malignant glioma. Kennedy died the following year.

9-Sep-2011 12:40 PM EDT
Study Reveals Critical Similarity Between Two Types of Do-It-All Stem Cells
University of Wisconsin–Madison

In a study published today (Sunday, Sept. 11), researchers at the University of Wisconsin-Madison report the first full measurement of the proteins made by both types of stem cells. In a study that looked at four embryonic stem cells and four IPS cells, the proteins turned out to be 99 percent similar, says Joshua Coon, an associate professor of chemistry and biomolecular chemistry who directed the project.

7-Sep-2011 9:00 AM EDT
Hormone Predicts Which Kidney Patients Might Die Early
American Society of Nephrology (ASN)

1) High blood levels of the hormone FGF-23 warn of heart problems, need for dialysis, and early death among chronic kidney disease patients. 2) Tests for FGF-23 could identified those at risk. 3) 60 million people globally have chronic kidney disease, and most die from heart-related problems.

8-Sep-2011 4:00 PM EDT
Early Motor Experiences Give Infants a Social Jump Start
Kennedy Krieger Institute

Study indicates infants at risk for autism could benefit from motor training.

6-Sep-2011 2:00 PM EDT
Concurrent Chemo and Radiation Therapy Improves Long-Term Survival for Inoperable Stage III Lung Cancer
American College of Radiology (ACR)

Nearly 50,000 Americans are diagnosed each year with stage III or locally advanced NSCLC, for which surgery is usually not a viable treatment option. Optimizing nonsurgical treatment strategies for these patients is an ongoing research endeavor. In the August xx, 2011 issue of the Journal of the National Cancer Institute, RTOG researchers report that treating patients with concurrent chemotherapy and radiation therapy significantly increased five-year survival rates compared with treating patients with radiation therapy upon completion of chemotherapy treatment.

1-Sep-2011 11:00 AM EDT
Teeny Teeth Indicate Ancient Shark Nurseries
Society of Vertebrate Paleontology

Scientists have suggested that some ancient sharks bred in the shallows of freshwater lakes, forming nurseries for their hatchlings. Reporting in the most recent issue of the Journal of Vertebrate Paleontology, a team of German paleontologists support this claim with spectacular 230 million-year-old fossil egg capsules and tiny teeth from Kyrgyzstan.

6-Sep-2011 9:05 AM EDT
Polymer from Brown Algae May Boost Battery Performance
Georgia Institute of Technology, Research Communications

By looking to Mother Nature for solutions, researchers have identified a promising new binder material for lithium-ion battery electrodes that could not only boost energy storage, but also eliminate the use of toxic compounds now used in manufacturing the components.

7-Sep-2011 4:45 PM EDT
Newly Discovery Heart ‘Mechanism’ to Provide New Targets for Heart Therapies
University of Maryland, Baltimore

University of Maryland researchers patented and licensed a “Bio-glue” that allows simulation of mechanical and chemical heartbeats from a single cell.

2-Sep-2011 12:40 PM EDT
Medical Management Alone May Be Best Treatment Course for Stroke Prevention
RUSH

Patients with narrowed arteries in the brain who received intensive medical treatment had fewer strokes and deaths than patients who received a brain stent in addition to medical treatment, according to the initial results from the first, nationwide stroke prevention trial to compare the two treatment options. The results of the National Institutes of Health (NIH) study called Stenting versus Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) are published in the online first edition of the New England Journal of Medicine.

6-Sep-2011 3:00 AM EDT
Sorting Out Major Brain Stent Study: Cedars-Sinai Experts Say Procedure Effective for Some Patients
Cedars-Sinai

An article appearing in the Sept. 7 New England Journal of Medicine, reporting on NIH research on brain stents, says aggressive medical treatment without stenting is better for high-risk stroke patients. But experts at Cedars-Sinai Medical Center who were involved in the study believe this procedure is appropriate for some patients. They say this study is a helpful start but not likely to be the final word on understanding when stenting may be appropriate, and raise concerns about several study limitations and exclusions.

7-Sep-2011 12:00 PM EDT
Stroke Prevention Trial Has Immediate Implications for Treating Patients
Houston Methodist

People who received intensive medical treatment following a first stroke had fewer second episodes and were less likely to die than people who received brain stents in addition to medical treatment, according to a new report in the New England Journal of Medicine, to be published online Sept. 7. All patients in the study had experienced one stroke and were considered at high risk for a second one.

6-Sep-2011 11:00 AM EDT
Study Points to Strategy for Overcoming Resistance to Targeted Cancer Drug
Dana-Farber Cancer Institute

Dana-Farber Cancer Institute researchers have discovered a pair of backup circuits in cancer cells that enable the cells to dodge the effect of cetuximab. Until now, scientists haven't known why cancers that initially respond to cetuximab become resistant to it, or how to overcome such resistance.

6-Sep-2011 9:05 AM EDT
Mount Sinai Researchers Find Promising New Target in Treating and Preventing the Progression of Heart Failure
Mount Sinai Health System

Researchers at Mount Sinai School of Medicine have identified a new drug target that may treat and/or prevent heart failure, published in this week's Nature.

2-Sep-2011 2:15 PM EDT
Fetal Tissue Plays Pivotal Role in Formation of Insulin-Producing Cells
University of California, San Francisco (UCSF)

A somewhat mysterious soft tissue found in the fetus during early development in the womb plays a pivotal role in the formation of mature beta cells the sole source of the body’s insulin. This discovery, made by scientists at University of California, San Francisco (UCSF) and Texas A&M University, may lead to new ways of addressing Type 1 and Type 2 diabetes.

1-Sep-2011 9:30 AM EDT
Looking for the Roots of Racial Bias in Delivery of Health Care
Johns Hopkins Medicine

New Johns Hopkins research shows that medical students — just like the general American population — may have unconscious if not overt preferences for white people, but this innate bias does not appear to translate into different or lesser health care of other races.

1-Sep-2011 4:35 PM EDT
BRCA1 Gene Mutation Associated with Neoadjuvant Chemotherapy
University of Texas MD Anderson Cancer Center

Inherited BRCA1 gene mutation associated with better response to neoadjuvant chemotherapy in breast cancer patients.

2-Sep-2011 12:55 PM EDT
Research Review Finds Simulation an Effective Way to Train Health Care Professionals
Mayo Clinic

An analysis led by Mayo Clinic (http://www.mayoclinic.org/) researchers found that simulation-based training is an effective way to teach physicians, nurses, dentists, emergency medical technicians and other health professionals.

31-Aug-2011 5:05 PM EDT
Anti-Inflammatory Drugs Taken in Early Pregnancy More than Double Risk of Miscarriage
Universite de Montreal

The risk of miscarriage is 2.4 times greater for women who took any type and dosage of nonaspirin nonsteroidal anti-inflammatory drugs (NSAIDs) in early pregnancy, according to a University of Montreal study in CMAJ.

6-Sep-2011 8:00 AM EDT
Structural Engineering Expert Explains How 9/11 Terrorists Came Up Short
Michigan Technological University

As deadly as the attacks on the World Trade Center were, thousands more could have perished if the towers had fallen immediately.

1-Sep-2011 3:35 PM EDT
No Link Between Menopause and Increased Risk of Fatal Heart Attack
Johns Hopkins Medicine

Contradicting the long-held medical belief that the risk of cardiovascular death for women spikes sharply after menopause, new research from Johns Hopkins suggests instead that heart disease mortality rates in women progress at a constant rate as they age.

30-Aug-2011 2:45 PM EDT
Non-Epileptic Seizures May Be Misdiagnosed Longer in Veterans
American Academy of Neurology (AAN)

Psychogenic non-epileptic seizures may go undiagnosed for much longer in veterans compared to civilians, according to a new study published in the September 6, 2011, print issue of Neurology®, the medical journal of the American Academy of Neurology. This type of seizure is different from seizures related to epilepsy and is thought to have a psychological origin.

1-Sep-2011 4:05 PM EDT
Researchers Find Missing Genes May Separate Coach Potato from Active Cousin
McMaster University

Thousands of scientists around the world are working on AMPK but the McMaster team is the first to demonstrate its essential role in exercise. Their research appears in the current issue of the Proceedings of the National Academy of Sciences.

1-Sep-2011 9:00 AM EDT
World's Smallest Electric Motor Made From a Single Molecule
Tufts University

Chemists at Tufts University's School of Arts and Sciences have developed the world's first single molecule electric motor, a development that may potentially create a new class of devices that could be used in applications ranging from medicine to engineering.

2-Sep-2011 2:00 PM EDT
TB Vaccine Candidate Shows Early Promise
Albert Einstein College of Medicine

Researchers at Albert Einstein College of Medicine of Yeshiva University report in the September 4 online edition of Nature Medicine that they have developed a tuberculosis (TB) vaccine candidate that proved both potent and safe in animal studies. According to the World Health Organization, TB kills an estimated 1.7 million people each year and infects one out of three people around the globe. With drug-resistant strains spreading, a vaccine for preventing TB is urgently needed.

31-Aug-2011 3:15 PM EDT
ATS Publishes Clinical Practice Guidelines on Interpretation of FENO Levels
American Thoracic Society (ATS)

The American Thoracic Society has issued the first-ever guidelines on the use of fractional exhaled nitric oxide (FENO) address when to use FENO and how to interpret FENO levels in different clinical settings. The guidelines, which appear in the September 1 American Journal of Respiratory and Critical Care Medicine, are graded based on the available evidence in the literature.

25-Aug-2011 1:00 PM EDT
Feeding Cows Natural Plant Extracts Can Reduce Dairy Farm Odors and Feed Costs
American Chemical Society (ACS)

With citizens’ groups seeking government regulation of foul-smelling ammonia emissions from large dairy farms, scientists today reported that adding natural plant extracts to cow feed can reduce levels of the gas by one-third while reducing the need to fortify cow feed with expensive protein supplements. They reported here at the 242nd National Meeting & Exposition of the American Chemical Society (ACS).

1-Sep-2011 9:00 AM EDT
Signs of Aging May be Linked to Undetected Blocked Brain Blood Vessels
RUSH

Many common signs of aging, such as shaking hands, stooped posture and walking slower, may be due to tiny blocked vessels in the brain that can’t be detected by current technology.

1-Sep-2011 11:20 AM EDT
From Paint to Pastes, Physicists Capture Microscopic Origins of Thinning and Thickening Fluids
Cornell University

In things thick and thin: Cornell physicists explain how fluids – such as paint or paste - behave by observing how micron-sized suspended particles dance in real time. Using high-speed microscopy, the scientists unveil how these particles are responding to fluid flows from shear – a specific way of stirring.

30-Aug-2011 1:45 PM EDT
Two Genes that Cause Familial ALS Shown to Work Together
Columbia University Irving Medical Center

Although several genes have been linked to amyotrophic lateral sclerosis (ALS), it is still unknown how they cause this progressive neurodegenerative disease. In a new study, Columbia University Medical Center (CUMC) researchers have demonstrated that two ALS-associated genes work in tandem to support the long-term survival of motor neurons. The findings were published in the September 1 online edition of the Journal of Clinical Investigation.

30-Aug-2011 5:00 PM EDT
Scientists Discover Secret Life of Chromatin
University of Texas MD Anderson Cancer Center

DNA/histone combination, a destination for cell signals, also talks to other proteins

30-Aug-2011 12:50 PM EDT
SmokingPaST Framework: New Planning Tool Helps Employers, Towns and State and National Policymakers Determine Lives Saved, and ROI from Tobacco Treatment Efforts
American Journal of Health Promotion

The newly released Smoking Prevalence, Savings, and Treatment (SmokingPaST) Framework is a tool designed to calculate the impact of investments in tobacco treatment programs on health and medical cost savings. The framework combines what is already known about the medical costs of smoking, the health benefits of quitting and the effectiveness of different quit methods.

25-Aug-2011 1:00 PM EDT
“Plastic Bottle” Solution for Arsenic-Contaminated Water Threatening 100 Million People
American Chemical Society (ACS)

With almost 100 million people in developing countries exposed to dangerously high levels of arsenic in their drinking water, and unable to afford complex purification technology, scientists today described a simple, inexpensive method for removing arsenic based on chopped up pieces of ordinary plastic beverage bottles coated with a nutrient found in many foods and dietary supplements.

25-Aug-2011 1:00 PM EDT
Potatoes Reduce Blood Pressure in People with Obesity and High Blood Pressure
American Chemical Society (ACS)

The potato’s stereotype as a fattening food for health-conscious folks to avoid is getting another revision today as scientists report that just a couple servings of spuds a day reduces blood pressure almost as much as oatmeal without causing weight gain. Scientists reported on the research, done on a group of overweight people with high blood pressure, at the 242nd National Meeting & Exposition of the American Chemical Society (ACS), being held here this week.

31-Aug-2011 11:00 AM EDT
Federal Investment in Electronic Health Records Likely to Reap Returns in Quality of Care
Case Western Reserve University

Research published today in the New England Journal of Medicine gives cause for optimism that federal investments in electronic health records could reap major benefits in better patient care and health outcomes.

31-Aug-2011 11:25 AM EDT
CPR Studies Recommend ‘Stay the Course’
University of Alabama at Birmingham

Researchers with the Resuscitation Outcomes Consortium, which includes UAB, report in the New England Journal of Medicine on the first two large-scale ROC trials. Both trials were evaluating new strategies for cardiopulmonary resuscitation following cardiac arrest.

23-Aug-2011 1:15 PM EDT
Choice of Seizure Drug for Brain Tumor Patients May Affect Survival
American Academy of Neurology (AAN)

New research suggests brain tumor patients who take the seizure drug valproic acid on top of standard treatment may live longer than people who take other kinds of epilepsy medications to control seizures. The research is published in the August 31, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology.



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