A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA—loops of DNA found outside of regular chromosomes—are twice as likely to relapse and three times as likely to die within five years of diagnosis.
Scientists know very little about conditions in the ocean when life first evolved, but new research published in Nature Geoscience has revealed how geological processes controlled which nutrients were available to fuel their development.
Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the “Christchurch mutation” can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer’s disease.
In a paper published today in Nature Climate Change, an international team of academics explore the ways in which research has shown that a changing environment affects how our brains work, and how climate change could impact our brain function in the future.
In a recent publication in Nature Communications, a joint research team of Johannes Gutenberg University Mainz (JGU), the University of Cologne, and the University of Oldenburg has presented their findings on the functioning of an atypical cryptochrome protein (Cry).
The team reduced the amount of expensive platinum group metals needed to make an effective cell and found a new way to test future fuel cell innovations.
Today an international research team, including scientists from the University of Vienna’s Environment and Climate Hub, introduces a unique approach in fighting the climate crisis.
An international team led by scientists from the University of Liège has observed, for the first time in the visible range, a glow on the night side of the planet Mars. These new observations provide a better understanding of the dynamics of the upper atmosphere of the Red Planet and its variations throughout the year.
Roughly two decades ago, a community-wide reckoning emerged concerning the credibility of published literature in the social-behavioral sciences, especially psychology.
Physicists from the University of Luxembourg together with experts from Avant-garde Materials Simulation (AMS) and seven pharmaceutical companies have redefined the state-of-the-art in modeling and predicting the free energy of crystals.
A new study shows how targeted advertising messages can increase demand for solar systems.
Michigan State University researchers have solved the mystery of a poorly understood sperm structure called the cytoplasmic droplet, or CD. The CD is an expanded cytoplasm — watery, gel-like cell contents enclosed by cell membrane — found close to the head, at the neck of the sperm, in all mammals, including humans. This new genetic model is the first of its kind.
UCI researchers identified a gene critical for muscle repair, paving the way for lab-grown muscle to treat muscle disorders and injuries.
New device could improve the outcomes of cell-based therapies
Alamar Biosciences announces publication of paper on NULISA technology, a novel immunoassay with attomolar sensitivity and high multiplexing.
Researchers have developed a new method to image polymerization catalysis reactions one monomer at a time.
A multicenter study led by researchers at Sylvester Comprehensive Cancer Center shows how interactions between tumor cells and immune components of the microenvironment can impact treatment responses and outcomes in patients newly diagnosed with multiple myeloma who undergo combination treatments that include targeted immunotherapy.
Making decisions is hard. Even when we know what we want, our choice often leaves something else on the table. For a hungry mouse, every morsel counts. But what if the decision is more consequential than choosing between crumbs and cheese?
Off Barbados, researchers from Bremen have investigated how bacteria inadvertently release methane in order to obtain phosphorus – with significant effects on atmospheric greenhouse gases.
Asian malaria mosquito found to spread drug and diagnosis-resistant malaria in Africa.
Researchers found that one of the most promising electrolytes for designing longer lasting lithium batteries has complex nanostructures that act like micelle structures do in soaped water.
Research consortium investigators analyzed over 314,000 cells from rheumatoid arthritis tissue, defining six types of inflammation involving diverse cell types and disease pathways
The results open the door to exploring superconductivity and other exotic electronic states in three-dimensional materials.
Un equipo de astrónomos consiguió capturar en imágenes los restos erosionados de más de un centenar de galaxias enanas que se están transformando en galaxias enanas ultra compactas, es decir, en objetos con masas mayores que la de los cúmulos estelares, pero mucho más pequeñas que las galaxias enanas. Los hallazgos fueron realizados utilizando el telescopio de Gemini Norte, la mitad boreal del Observatorio Gemini que opera NOIRLab de NSF y AURA, y confirman que muchas galaxias enanas ultra compactas son probablemente los fósiles de galaxias enanas normales cuyas capas exteriores se desprendieron.
New hope for other nervous system disorders like ALS
Astronomers using the Gemini North telescope, one half of the International Gemini Observatory operated by NSF’s NOIRLab, have captured the eroding remains of more than 100 dwarf galaxies as they transition into ultra-compact dwarf galaxies, objects with masses much greater than star clusters yet much smaller than dwarf galaxies.
A research team led by Lawrence Berkeley National Laboratory has developed a high-performance coating material that self-assembles from 2D nanosheets, and which could significantly extend the shelf life of electronics, energy storage devices, health & safety products, and more. The researchers are the first to successfully scale up nanomaterial synthesis into useful materials for manufacturing and commercial applications.
A new report in Nature Geoscience has brought to light the challenge of air pollution levels in Africa and why international action is needed to combat it.
The largest floating ice shelves in the polar ice sheet have lost more than a third of their volume since 1978.
Researchers with the Translational Research in Neuroimaging and Data Science (TReNDs) Center at Georgia State have identified important new methods for accurately identifying possible biomarkers in adolescent brains that can reliably predict cognitive developments and psychiatric issues.
Scientists have unlocked the genetic basis underlying the remarkable variation in body size observed in song sparrows, one of North America’s most familiar and beloved songbirds. This discovery also provides insights into this species’ capacity to adapt to the challenges of climate change.
Whole genome sequencing of North American song sparrows has revealed the genetic underpinnings for a stunning range of body sizes found throughout the bird’s westernmost range—an adaptation that may make the birds more resilient to climate change. This work is the first output from a larger research effort to sequence song sparrow genomes from across North America, spanning nearly all of the 25 recognized subspecies.
CAR-T cell therapy is a last hope for many patients with blood, bone marrow or lymph gland cancer when other treatments such as chemotherapy are unsuccessful. A limiting factor of this otherwise very effective and safe therapy is that the cells used in the process quickly reach a state of exhaustion.
Researchers combined the features of clinical drugs to treat hepatitis C and viruses similar to COVID-19. This allowed them to synthesize BBH-1, a promising inhibitor that targets the breakdown of the SARS-CoV-2 virus. The researchers characterized samples using X-ray and neutron diffraction techniques to provide atomic-level insights on the structure of the BBH-1 inhibitor and how it binds to the SARS-CoV-2 protein.
Irvine, Calif., Nov. 6, 2023 — Agriculture is one of the hardest human activities to decarbonize; people must eat, but the land-use practices associated with growing crops account for roughly a quarter of global greenhouse gas emissions. Researchers at the University of California, Irvine and other institutions evaluate a new solution to this problem, one that eliminates farms altogether.
Prosthetic decodes signals from brain’s speech center to predict what sound someone is trying to say.
In a world grappling with a severe water crisis, contamination is a looming threat to public health. Researchers at the U.S. Department of Energy’s Argonne National Laboratory and partners have engineered a breakthrough solution.
Leading modeling experts from the U.S. Department of Energy’s Argonne National Laboratory and other institutions are sounding the alarm about the urgent need for improved energy system models in a recent Nature Energy paper.
A new pathologic scoring system that accurately assesses how much lung tumor is left after a patient receives presurgical cancer treatments can be used to predict survival, according to new research led by investigators at the Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center and the Mark Foundation Center for Advanced Genomics and Imaging at the Johns Hopkins University.
In order to survive, organisms must control the pressure inside them, from the single-cell level to tissues and organs. Measuring these pressures in living cells and tissues in physiological conditions is a challenge.
The USA is likely to see consistent job growth from the transition to net zero, but the gains will be unevenly distributed, shows a new analysis. The analysis, conducted by Imperial College London researchers and published today in Nature Climate Change, shows that some states will need new policies to ensure a ‘just’ transition.
Do we really know how the brain works? In the last several decades, scientists have made great strides in understanding this fantastically complex organ. Scientists now know a great deal about the brain’s cellular neurobiology and have learned much about the brain’s neural connections, and the components that make up these connections.
Superfluid feels two-dimensional to touch, with heat flowing along the edges of your finger.
A new study takes an important step toward reconstructing a global history of water over the past 2,000 years. Using geologic and biologic evidence preserved in natural archives — including globally distributed corals, trees, ice, cave formations and sediments — the researchers showed that the global water cycle has changed during periods of higher and lower temperatures in the recent past.
Nanoengineers have created a quasicrystal—a scientifically intriguing and technologically promising material structure—from nanoparticles using DNA, the molecule that encodes life.
In the 1980s, geophysicists made a startling discovery: two continent-sized blobs of unusual material were found deep near the center of the Earth, one beneath the African continent and one beneath the Pacific Ocean.
A new analysis of the bones and muscles in ancient fish gives new clues about how the shoulder evolved in animals – including us.
A pioneering study led by the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore and the University of Cambridge (UK) has uncovered vital insights into the distinct effects of BRCA2 mutations on breast tissue cells, shedding light on early breast cancer development in people with BRCA2 mutations.
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