Cabozantinib, which targets tumor cell growth and tumor blood vessel growth, sharply improved progression-free survival over placebo in patients with extra-pancreatic and pancreatic neuroendocrine tumors
Perioperative immunotherapy plus neoadjuvant chemotherapy significantly improved event-free survival (EFS) in patients with resectable early-stage non-small cell lung cancer (NSCLC) compared to chemotherapy alone. Results from the Phase III CheckMate 77T study were presented today at the 2023 European Society of Medical Oncology (ESMO) Congress by researchers from The University of Texas MD Anderson Cancer Center.
Belzutifan significantly reduced the risk of progression of clear cell renal cell carcinoma (ccRCC), the most common type of kidney cancer, in patients previously treated with immune checkpoint inhibitors and anti-angiogenic therapies compared with everolimus in a phase 3 clinical trial.
Stimulating muscle fibers with magnets causes them to grow in the same direction, aligning muscle cells within tissue, Massachusetts Institute of Technology (MIT) and Boston University investigators report October 20 in the journal Device.
Researchers are studying the dramatic physical transformation that some insects undergo to give birth to live young.
Currently, the biggest hurdle for electric vehicles, or EVs, is the development of advanced battery technology to extend driving range, safety and reliability.New research has shown how a novel lithium-based electrolyte material (Li9N2Cl3) can be used to develop solid-state batteries that charge faster and store more energy than conventional designs.
Conventional sensors usually lack the sensitivity needed for studies of quantum phenomena and other complex cases. One solution is to use superconducting sensors, but amplifying their signals is challenging. Researchers built on advances from quantum computing to add a special type of amplifiers, superconducting traveling-wave parametric amplifiers, to superconducting sensors. These amplifiers are almost noiseless and operate at relatively high temperatures.
Scientists at the Department of Energy’s Oak Ridge National Laboratory used carefully planned chemical design, neutron scattering and high-performance computing to help develop a new catalytic recycling process. The catalyst selectively and sequentially deconstructs multiple polymers in mixed plastics into pristine monomers. The new organocatalyst has proven to efficiently and quickly deconstruct multiple polymers — in around two hours. Such polymers include those used in materials such as safety goggles (polycarbonates), foams (polyurethanes), water bottles (polyethylene terephthalates) and ropes or fishing nets (polyamides), which together comprise more than 30% of global plastic production. Until now, no single catalyst has been shown to be effective on all four of these polymers.
Tattoo removal may help to reduce violence and trauma in East Los Angeles, according to study results being presented at the American College of Surgeons (ACS) Clinical Congress 2023.
Adjustments in school boundaries and other forms of school redistricting have been linked to spikes in shooting-related injuries in urban areas, according to new study results being presented at the American College of Surgeons (ACS) Clinical Congress 2023.
Ten years after the creation of Rutgers Biomedical and Health Sciences, new university institutes and centers are bringing the world’s best medical ideas to New Jersey and beyond
A research facility in Ethiopia now bears the name of Curtis Youngs, recognizing the Iowa State University animal science professor’s pivotal contributions to ongoing programs to enhance dairy cattle genetics in the region. The overarching aim is to increase food security in Africa’s top livestock-producing nation by boosting milk production.
The Endocrine Society and the European Society of Endocrinology (ESE) are delighted to announce that they have awarded the 2024 Transatlantic Alliance Award to Professor Felix Beuschlein, MD.
Dr. Jae-Woo Choi of the Center for Water Cycle Research at the Korea Institute of Science and Technology (KIST) has developed an eco-friendly metal-organic skeleton-based solid flocculant that can effectively aggregate nanoplastics under visible light irradiation.
Consistently sleeping less than five hours a night might raise the risk of developing depressive symptoms, according to a new genetic study led by UCL researchers.
Argonne National Laboratory is training financial professionals to identify and avoid relationships with sanctioned or other high-risk entities that deal in advanced conventional weapons.
In a finding that helps elucidate how molten salts in advanced nuclear reactors might behave, scientists have shown how electrons interacting with the ions of the molten salt can form three states with different properties.
Seven private companies demonstrate the impact of partnering with the U.S. Department of Energy and its national laboratories to advance nuclear reactor designs, fight climate change and provide secure energy to the nation.
Jupiter has some of the most conspicuous atmospheric features in our solar system. The planet’s Great Red Spot, large enough to envelop Earth, is nearly as well known as some of the various rivers and mountains on the planet we call home. However, much like Earth, Jupiter is ever-changing, and there’s much about the planet we have yet to learn. NASA’s James Webb Space Telescope is unlocking some of those mysteries, revealing new features of Jupiter we’ve never seen before, including a high-speed jet speeding over the planet’s equator. While the jet stream is not as visually apparent or stunning as some of Jupiter’s other features, it’s giving researchers incredible insight into how the layers of the planet’s atmosphere interact with each other, and how Webb will aid in these investigations in the future.
Researchers have been able to pinpoint exactly when the muddy off-flavor emerges in farmed fish, which could help to make it easier to deal with the compounds that turn people away from farmed fish
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During the Early-Middle Devonian period, a large landmass called Gondwana—which included parts of today's Africa, South America, and Antarctica—was located near the South Pole. Unlike today's icy conditions, the climate was warmer, and the sea levels were higher, flooding most of the land.
Researchers at The University of Texas MD Anderson Cancer Center have discovered that lactate-producing intratumoral bacteria drives resistance to radiation therapy, suggesting that lactic acid-producing bacteria present in various cancers may serve as novel therapeutic targets. The study, published today in Cancer Cell, reported that a particular bacterial species, Lactobacillus iners (L. iners), caused cancer cells to respond to radiation by rewiring metabolic signaling pathways to resist treatment. The researchers also found that L. iners was associated with poorer clinical outcomes in patients with cervical cancer.
UC San Diego engineers have developed a recipe to make a certain class of ceramics tougher and more resistant to cracking. The newfound toughness of these ceramics paves the way for their use in extreme applications, such as spacecraft and other hypersonic vehicles.
Researchers at Kyushu University have discovered that turning brain immune cells into neurons successfully restores brain function after stroke-like injury in mice. These findings, published on October 10 in PNAS, suggest that replenishing neurons from immune cells could be a promising avenue for treating stroke in humans.
Today, The George Washington University (GW) School of Medicine and Health Sciences (SMHS), in collaboration with Pfizer Global Medical Grants, announces that four institutions will be awarded grants to implement GW’s Teledermatology clinic model in underserved areas across the United States. Targeting those who lack access to quality-based care for inflammatory dermatologic conditions, including Atopic Dermatitis (AD) and others, the grants will reach communities in Miami-Dade County, Florida, Los Angeles County, California, rural communities in Oregon, and downtown Philadelphia, PA.
Until now, scientists struggled to understand why some men experienced more side effects resulting from radiation therapy than others. New, Corewell Health research offers assurance to those who can now worry less about possible complications.
Astronomers have created a detailed atlas of almost 400,000 galaxies in our cosmic neighborhood. The Siena Galaxy Atlas was primarily built from data gathered in preparation for the Dark Energy Spectroscopic Instrument (DESI) experiment and will be an invaluable tool for research into gravitational waves, dark matter, the structure of our universe, and how galaxies evolve.
Taking inspiration from music streaming services, a team of engineers at the University of Michigan, Google and Georgia Tech has designed the simplest way for users to program their own exoskeleton assistance settings.
Identifying different types of body fluids can help forensic experts reconstruct a crime scene, but it’s difficult to do so
Researchers propose a novel approach that utilizes deep learning to generate three-dimensional holograms from colored two-dimensional images
A team from the Vehicle Safety Institute at TU Graz has used Human Body Models to investigate accidents involving electric scooters and identified the most important factors for preventing serious injuries
Special nanoparticles could one day improve modern imaging techniques. Developed by researchers at Martin Luther University Halle-Wittenberg (MLU), the properties of these unique nanoparticles change in reaction to heat. When combined with an integrated dye, the particles may be used in photoacoustic imaging to produce high-resolution, three-dimensional internal images of the human body
Klick Labs scientists discover voice tech as potential game changer in Type 2 diabetes detection
Australian researchers have developed a wearable device that can generate power from a user's bending finger and store memories
UC San Diego engineers have developed an experimental vaccine that could prevent the spread of metastatic cancers to the lungs. Its success lies in targeting a protein known to play a central role in cancer growth and spread, rather than targeting the primary tumor itself.
The Korea Institute of Science and Technology (KIST) announced that have presented a new artificial intelligence-based catalyst screening methodology and succeeded in developing a new catalytic material based on a ternary element-based alloy (Cu-Au-Pt) that is cheaper and performs more than twice as well as pure platinum catalysts.
In a world where unexpected emergencies and natural disasters are ever-present, preparedness is paramount. The American College of Surgeons (ACS) recently released the online version of its Disaster Management and Emergency Preparedness (eDMEP) course, making this important content accessible to a wider audience.
Michal Schnaider Beeri and team analyzed data from 100,000 people to determine if ADHD in adults leads to higher risk of dementia.
In APL Materials, researchers tested a molecular energy harvesting device that captures the energy from the natural motion of molecules in a liquid. Their work showed molecular motion can be used to generate a stable electric current. To create the device, they submerged nanoarrays of piezoelectric material in liquid, allowing the movement of the liquid to move the strands like seaweed waving in the ocean, except in this case the movement is on the molecular scale, and the strands are made of zinc oxide. When the zinc oxide material waves, bends, or deforms under motion, it generates electric potential.
Climate change and the rapid increase in frequency of extreme weather events around the globe reinforces the reality that these events are interconnected. In Chaos, researchers describe a climate network analysis method to explore the intensity, distribution, and evolution of this interlinked climate behavior, or teleconnections. The analysis combines the directions and distribution patterns of teleconnections to evaluate their intensity and to identify sensitive regions using global daily surface air temperature data. The method relies on advanced data processing and mathematical algorithms to find meaningful insights.
This is the first to explore the potential relationship between DED and air pollution and meteorological conditions in cold region of Northeast China. The incidence of DED is positively correlated with PM10, CO, O3, air pressure, air temperature and wind speed. The combined impacts of PM10, NO2, air pressure and air temperature are stronger. This study provides a reference for air pollution prevention and climate control, highlighting the importance of coupling study for drug development and risk prediction.
Highly vulnerable patients with alcohol use disorder (AUD) or substance use disorder (SUD) who received regular assessments after their initial intervention had substantially better outcomes a year later than those who did not receive the same follow-up, according to a new study. Fewer than one in ten people with SUD receive any form of treatment in a given year; among those who do, relapse and treatment reentry are common. A Screening, Brief Intervention, and Referral to Treatment (SBIRT) protocol is intended to facilitate treatment referrals, especially among patients with more severe SUDs, but research has shown it to be relatively ineffective in that regard. Adding a Recovery Management Checkup (RMC) intervention can improve treatment rates; RMC conceptualizes AUD and SUD as chronic conditions requiring longer-term monitoring via regular check-ins, early re-intervention in cases of relapse, and treatment retention strategies. For the study in Alcohol: Clinical & Experimental Resear
Can exercise, intermittent fasting and other lifestyle changes help patients with advanced breast cancer better tolerate side effects from treatment? A new $4-million NCI-funded study at Sylvester Comprehensive Cancer Center seeks to answer that question.
New technique could be used in medical diagnostics and advanced manufacturing.
The Korea Institute of Science and Technology (KIST) announced that has developed a new zero-dimensional and two-dimensional (2D-0D) semiconductor artificial junction material and observed the effect of a next-generation memory powered by light.
Nanozymes are synthetic materials that mimic the properties of natural enzymes for applications in biomedicine and chemical engineering. They are generally considered too toxic and expensive for use in agriculture and food science.
Ronald M. Stewart, MD, FACS, a trauma surgeon from San Antonio, Texas, will receive this year’s Distinguished Service Award of the American College of Surgeons (ACS).
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