A new anti-asthma medication dramatically reduced increases in seasonal asthma attacks in children and young adults with allergic asthma, according to a multi-institutional study involving a UT Southwestern Medical Center physician.
Earth remote sensing satellites and social networking tools are in use to help respond to the multi-prong tragedy in Japan of earthquake, tsunami, and the crippling of nuclear power plants.
From 1965 to 2007, the population prevalence of persons who smoked 20 or more cigarettes per day declined significantly, and there was also a decrease in the prevalence of smoking 10 or more cigarettes a day, with these declines greater in California than in the rest of the U.S., according to a study in the March 16 issue of JAMA.
Modifying a patient’s dosage of the antiplatelet drug clopidogrel for 6 months depending on the patient’s level of platelet reactivity did not result in combined lower rates of nonfatal heart attack, stent thrombosis (clot) and cardiovascular death in patients who had a procedure such as balloon angioplasty and received a drug-releasing coronary stent, according to a study in the March 16 issue of JAMA.
An examination of data for more than 5 million Medicare beneficiaries finds that hospital regions that have a greater frequency of diagnoses have a lower case-fatality rate for chronic conditions such as coronary artery disease and kidney failure, according to a study in the March 16 issue of JAMA.
Even though clinical practice guidelines for patients with chronic kidney disease recommend specific treatment target levels for serum phosphorus, parathyroid hormone, and calcium to reduce the risk of cardiovascular events, an analysis of data from previous studies did not find a strong association between these biomarkers and the risk of death and cardiovascular events, except for higher serum phosphorus levels, according to an article in the March 16 issue of JAMA.
An inexpensive type 2 diabetes drug that has been around for more than 15 years works just as well and has fewer side effects than a half-dozen other, mostly newer and more expensive classes of medication used to control the chronic disease, new Johns Hopkins research suggests.
People who have a stroke are more likely to be dependent if they are depressed, older or have other medical problems, according to a study published in the March 15, 2011, print issue of Neurology®, the medical journal of the American Academy of Neurology.
Heavy alcohol consumption, specifically three or more glasses of liquor a day, is associated with an increased risk of death from pancreatic cancer, according to a report in the March 14 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
A meta-analysis of nine previous studies found that quitting smoking shortly before surgery was not associated with an increased risk of postoperative complications, according to a report published online today that will appear in the July 11 print issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
New research from the Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC) shows that newer, more expensive treatment options for prostate cancer were adopted rapidly and widely during 2002 – 2005 without proof of their cost-effectiveness.
Older people who receive Guided Care, a new form of primary care, use fewer expensive health services compared to older people who receive regular primary care.
The mystery of biodiversity – how thousands of similar species can co-exist in a single ecosystem – might best be understood as the result of a massive rock-paper-scissors tournament, a new study has revealed.
A new study in Honduras suggests that climate-related weather disasters may sometimes actually provide opportunities for the rural poor to improve their lives.
Calling it the “new periodic table for flies,” researchers at North Carolina State University and collaborators across the globe have mapped the evolutionary history of flies, providing a framework for further comparative studies on the insects that comprise more than 10 percent of all life on Earth.
In an article to appear in the April 2011 issue of the Notices of the American Mathematical Society, John W. Cain, a mathematician at Virginia Commonwealth University, presents a survey of six ongoing Challenge Problems in mathematical cardiology.
Breast cancer tumors take numerous paths to resist the targeted drug Herceptin, but a single roadblock at a crucial crossroads may restore a tumor's vulnerability to treatment, scientists at The University of Texas MD Anderson Cancer Center report on line at Nature Medicine.
Four novel biomarkers have been identified which may aid in the diagnosis and management of asthma and chronic obstructive pulmonary disease (COPD), according to a study conducted by researchers in Australia, who determined the biomarkers may be used in different combinations to successfully identify patients with either of the airway diseases. In conducting the study, the researchers relied on proteomics, an emerging field of science that focuses on the structure and functions of an organism’s proteins.
Monitoring blood for tiny particles released by cells lining the lungs may help clinicians diagnose emphysema in its earliest stages, according to researchers from Weill Cornell Medical College. The particles, called endothelial microparticles (EMPs), are shed during the disease process as tiny blood vessels in the lungs, called pulmonary capillaries, are injured and die.
During a regular annual physical exam, blood is usually drawn to check the health of a person's heart, kidneys and liver. Now, researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center say a blood test that detects the early development of emphysema -- well before symptoms occur -- may someday also be offered.
Depression is associated with an increased risk of developing kidney failure in the future, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). Approximately 10% of the US population will suffer from depression at some point during their lifetime.
Five genetic variants in humans – four new – associate with Nonalcoholic Fatty Liver Disease (NAFLD), according to a study published March 10 in PLoS Genetics.
A light-sensing receptor that’s packed inside the eye’s photoreceptor cells has an altogether surprising role in cells elsewhere in the body, Johns Hopkins scientists have discovered. Using fruit flies, they showed that this protein, called rhodopsin, also is critical for sensing temperature.
Researchers from across multiple disciplines at NYU Langone Medical Center created a new protein molecule derived from the growth factor progranulin may provide the basis for new therapies in inflammatory diseases, such as rheumatoid arthritis, according to a study published in the March 10, 2011 issue of Science.
Johns Hopkins Children’s Center researchers have discovered that most children with severe cerebral palsy have starkly asymmetric pelvic bones. The newly identified misalignment can affect how surgeries of the pelvis, spine and surrounding structures are performed, the researchers say.
Neena Singh, MD, PhD and colleagues at Case Western Reserve University School of Medicine have identified the first disease-specific biomarker for sporadic Creutzfeldt-Jakob disease (sCJD), a universally fatal, degenerative brain disease for which there is no cure.
Just when children are faced with intensifying peer pressure to misbehave, regions of the brain are actually blossoming in a way that heighten the ability to resist risky behavior, report researchers at three West Coast institutions.
Children in classrooms with inadequate material resources and children whose teachers feel they are not respected by colleagues exhibit more mental health problems than students in classrooms without these issues, finds a new study in the March issue of the Journal of Health and Social Behavior.
It’s all too familiar: researchers announce the discovery of a new drug that eradicates disease in animals. Then, a few years later, the drug bombs in human trials. Now, two medical ethicists argue that this pattern of boom and bust may be related to the way researchers predict outcomes of their work in early stages of drug development.
Communication technologies that help people stay connected to the workplace are often seen as solutions to balancing work and family life. However, a new study suggests there may be a “dark side” to the use of these technologies for workers’ health—and these effects seem to differ for women and men.
Nearly half of American teen drinkers would rather have a shot of liquor than a bottle of beer, a new study finds.
Researchers at the Institute for Regenerative Medicine at Wake Forest University Baptist Medical Center and colleagues reported today on a new advance in tissue engineering. The team is the first in the world to use patients’ own cells to build tailor-made urinary tubes and successfully replace damaged tissue.
Stroke survivors who have an irregular heartbeat called atrial fibrillation may be at higher risk of developing dementia than stroke survivors who do not have the heart condition, according to research published in the March 8, 2011, print issue of Neurology®, the medical journal of the American Academy of Neurology.
A new research study dramatically increases knowledge of how taste cells detect sugars, a key step in developing strategies to limit overconsumption. Scientists from the Monell Center and collaborators have discovered that taste cells have several additional sugar detectors other than the previously known sweet receptor.
Institute for Genome Sciences led pioneering investigation in new field of microbial forensics.
Young children who mouth or swallow jewelry containing cadmium may be exposed to as much as 100 times the recommended maximum exposure limit for the toxic metal, according to research published online March 4 ahead of print in the peer-reviewed journal Environmental Health Perspectives (EHP). The study measured bioavailability, or how much cadmium leached out of the jewelry. The research also found that damaged pieces of jewelry in some cases leached up to 30 times more cadmium than undamaged pieces.
Low physical activity increases kidney transplant patients’ likelihood of dying early, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The results suggest that patients need to exercise to fend off an early death.
Not all racial and ethnic groups have equal access to kidney transplantation, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results indicate that the reasons for these disparities are varied and that more focused efforts are needed to address them.
Vanderbilt researchers are studying heavy users of marijuana to help understand what exercise does for the brain, contributing to a field of research that uses exercise as a modality for prevention and treatment. Participants saw a significant decrease in their cravings and daily use after just a few sessions of running on the treadmill, according to a Vanderbilt study published today in the journal PLoS ONE. It is the first study to demonstrate that exercise can reduce cannabis use in persons who don't want to stop.
Evidence for a diversified sea-based economy among North American inhabitants dating from 12,200 to 11,400 years ago is emerging from three sites on California's Channel Islands.
Johns Hopkins scientists have discovered that PARIS — the protein — facilitates the most common form of Parkinson’s disease (PD), which affects about 1 million older Americans. The findings of their study, published March 4 in Cell, could lead to important new targets for treatment.
Patients with end-stage renal disease who opt for peritoneal dialysis experience no greater risk of catheter infection than those who undergo hemodialysis, a retrospective study at UT Southwestern Medical Center has found.
The public is on a different page with regard to the federal budget than either the House of Representatives or the Obama Administration, bringing a different set of priorities and a greater willingness to increase some domestic spending and taxes, concludes a new analysis by the University of Maryland’s Program for Public Consultation (PPC).
The discrimination that obese people feel, whether it is poor service at a restaurant or being treated differently in the workplace, may have a direct impact on their physical health, according to new research from Purdue University.
New research suggests that ibuprofen may offer protection against developing Parkinson’s disease, according to one of the largest studies to date investigating the possible benefits of the over-the-counter drug on the disease. The study is published in the March 2, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Researchers at the University of Michigan Comprehensive Cancer Center have identified a potential target to treat an aggressive type of prostate cancer. The target, a gene called SPINK1, could be to prostate cancer what HER2 has become for breast cancer.
Ordinary human cells reprogrammed as induced pluripotent stem cells may revolutionize personalized medicine by creating new and diverse therapies unique to individual patients. But important and unanswered questions have persisted about the safety of these cells, in particular whether their genetic material is altered during the reprogramming process. A new study finds that the genetic material of reprogrammed cells may in fact be compromised, and suggests that extensive genetic screening of hiPSCs become standard practice.
Animals’ capacity to adapt is a factor in how they are likely to respond to changing climate conditions.
1) Obese women had a 35 percent increased risk of breast cancer; 2) Risk was similar to increase in estrogen receptor-positive cancer; 3) Obesity may increase risk through mechanisms other than estrogen.
Many people suffer from a devastating condition known as critical limb ischemia (CLI) that can lead to muscle wasting and even amputation. The disease is linked to the blockage of blood flow to the skeletal muscle and current treatment options include rehabilitative exercise and surgical bypass of blood vessels. New preclinical research suggests there may be a way to restore blood supply in skeletal muscle without traditional intervention.
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