Feature Channels: Infectious Diseases

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Released: 29-Jul-2010 10:00 AM EDT
Study Finds Vaccination Strategies Could Help Slow Spread of Infectious Disease in Rural Areas
Kansas State University

The best way to prevent the spread of disease in rural areas may be by targeting select popular hangouts, according to a new study by the Kansas State University EpiCenter research team.

Released: 28-Jul-2010 11:50 AM EDT
Professor Uncovers Mysterious Workings of Cholera Bacteria
Rensselaer Polytechnic Institute (RPI)

Researchers have found that an enzyme in the bacteria that causes cholera uses a previously unknown mechanism in providing the bacteria with energy. Because the enzyme is not found in most other organisms, including humans, the finding offers insights into how drugs might be created to kill the bacteria without harming humans.

Released: 26-Jul-2010 4:00 PM EDT
Study Identifies Effective, Inexpensive Test for Tuberculosis in Children
Tulane University

An international team of researchers comparing recently-developed methods for diagnosing tuberculosis in children in resource-poor countries has concluded that the best test for high-risk children is the microscopic-observation drug-susceptibility (MODS) technique using two gastric aspirate specimens from each child tested.

Released: 21-Jul-2010 2:00 PM EDT
Don't Let Dengue Turn Your Florida Vacation Into a 'Bone-Aching' Experience
Loyola Medicine

Loyola infectious disease physician tells how to protect yourself, family from the dengue fever outbreak in the Sunshine State.

Released: 21-Jul-2010 4:50 AM EDT
Nature to Provide Eco-friendly Method for Reducing Mosquitoes
University of Haifa

New research at the University of Haifa has made a breakthrough in identifying chemical substances released by mosquitoes' natural predators that function as warning signals for egg laying mosquitoes.

Released: 19-Jul-2010 7:00 AM EDT
Half of HIV-Exposed Babies in Parts of Africa Not Receiving Available HIV Prevention Drug
University of Alabama at Birmingham

A JAMA study finds programmatic failures and common problems that occur along the path to mother-to-child transmission prevention, including HIV testing inadequacies and patients not taking their medications, authors say. Nevirapine's usefulness is limited by how many infected and at-risk persons receive the drug, says Elizabeth Stringer, M.D., UAB associate professor of obstetrics and gynecology and the lead author of the study in the JAMA HIV/AIDS theme issue.

15-Jul-2010 9:00 AM EDT
Dissolving Microneedles Improve Flu Vaccine Delivery
Georgia Institute of Technology, Research Communications

A new vaccine-delivery patch based on hundreds of microscopic needles that dissolve into the skin could allow persons without medical training to painlessly administer vaccines – while providing improved immunization against diseases such as influenza.

Released: 16-Jul-2010 10:40 AM EDT
Scientists Identify Nature's Insect Repellents
Rockefeller University

Two compounds emitted by mosquito predators that make the mosquitoes less inclined to lay eggs in pools of water may provide new environmentally friendly tactics for repelling and controlling disease-carrying insects.

Released: 16-Jul-2010 8:00 AM EDT
Dengue Fever Expert – GW’s Dr. Peter Hotez Available to Comment
George Washington University

Dr. Peter Hotez of The George Washington University Medical Center is available to comment on the recent outbreak of Dengue virus in the Florida Keys.

Released: 16-Jul-2010 8:00 AM EDT
Cancer Drugs May Help Stop Major Parasite
Washington University in St. Louis

A parasite estimated to afflict as many as 12 million people worldwide relies on a family of genes that should make it vulnerable to compounds developed to treat cancer and other disorders, researchers at Washington University School of Medicine in St. Louis have found.

9-Jul-2010 12:00 AM EDT
Bringing True Accountability to Health Care: Lessons from Efforts to Reduce Hospital-Acquired Infections
Johns Hopkins Medicine

In health care reform discussions, talk inevitably turns to making hospitals and physicians accountable for patient outcomes. But in a commentary being published in the July 14 issue of the Journal of the American Medical Association, Johns Hopkins patient safety expert Peter Pronovost, M.D., Ph.D., argues that the health care industry doesn’t yet have measurable, achievable and routine ways to prevent patient harm — and that, in many cases, there are too many barriers in the way to attain them.

Released: 13-Jul-2010 11:30 AM EDT
Newly Discovered Antibodies May Boost AIDS Vaccine Research
GeoVax Labs

GeoVax is developing a vaccine that presents the natural form of HIV envelope proteins to the immune system on virus-like particles with the envelope proteins present in clusters of three, a confirmation known as trimers.

9-Jul-2010 8:20 AM EDT
Couple-Focused Intervention Appears Effective in Reducing HIV Risk Behaviors Among African Americans
JAMA - Journal of the American Medical Association

A risk reduction program focused on African American heterosexual couples appears to diminish risky sexual behaviors among couples in which one partner is HIV-positive and the other is not, according to a report posted online today that will appear in the September 27 print issue of Archives of Internal Medicine, one of the JAMA/Archives journals. The study was published online today in advance of its upcoming presentation at the International AIDS Conference in Vienna, Austria.

Released: 12-Jul-2010 8:35 AM EDT
"Dawning of a New Age" in Bacteria Research
Loyola Medicine

Lowly bacteria are turning out to be much more complex than previously thought. Researchers describe an example of bacterial complexity which once was thought to be rare in bacteria.

Released: 8-Jul-2010 12:50 PM EDT
UC San Diego To Lead New Malaria Research Center in South America
UC San Diego Health

Tropical disease specialist Joseph Vinetz, MD, of the University of California, San Diego School of Medicine will lead an ambitious multi-national effort to help control and eventually conquer malaria, establishing a new Peruvian/Brazilian International Center of Excellence in Malaria Research Center (ICEMR) with a seven-year, $9.2 million grant from the National Institutes of Health.

Released: 6-Jul-2010 8:00 AM EDT
Map of Herpes Virus Protein Suggests a New Drug Therapy
Tufts University

New research reveals the unusual structure of a key protein complex that allows a herpes virus to invade cells. This close-up of the herpes virus’s “cell-entry machinery” sheds light on how herpes viruses work and provides a promising new target for antiviral drugs.

28-Jun-2010 1:25 PM EDT
Study Finds Higher STD Rates Among Users of Erectile Dysfunction Drugs
University of Southern California (USC)

The analysis of insurance records of more than 1.4 million U.S. men over 40 found that those who used ED drugs were more likely to have sexually transmitted diseases than were non-users. Physicians who prescribe erectile dysfunction drugs for their male patients should be sure to discuss the importance of safer sex practices, even with older patients.

1-Jul-2010 9:35 AM EDT
Researchers Urge Wider Use of Diarrheal Disease Control Measures
Johns Hopkins Bloomberg School of Public Health

Researchers from the Johns Hopkins Bloomberg School of Public Health urge wider use of oral rehydration solution (ORS), zinc supplementation and rotavirus vaccine to reduce the deaths from diarrheal disease worldwide. Diarrheal disease kills approximately 1.5 million children under age 5 each year. The researchers’ findings and recommendations are published in the July 3 edition of The Lancet.

28-Jun-2010 4:40 PM EDT
Stem Cell Therapy May Provide New Approach to Fight Infection
American Thoracic Society (ATS)

A new study from researchers in Ottawa and Toronto suggests that a commonly used type of bone marrow stem cell may be able to help treat sepsis, a deadly condition that can occur when an infection spreads throughout the body.

29-Jun-2010 12:55 PM EDT
Intervention Effort Cuts HIV Incidence Among Female Sex Workers
UC San Diego Health

A team of researchers from the University of California San Diego and Mexico has found that even a modest behavioral intervention program averaging just 35 minutes can measurably reduce the incidence of HIV and sexually transmitted infections (STIs) among female sex workers in the U.S.-Mexico border region – and that the program succeeds at comparatively little expense.

Released: 25-Jun-2010 1:20 PM EDT
Antioxidants May Help Prevent Malaria Complications That Damage Brain
University of Utah Health

Using an experimental mouse model for malaria, an international group of scientists has discovered that adding antioxidant therapy to traditional antimalarial treatment may prevent long-lasting cognitive impairment in cerebral malaria.

23-Jun-2010 3:30 PM EDT
Virus Works with Gene to Cause Crohn's-Like Illness
Washington University in St. Louis

Scientists have shown that a specific virus can interact with a mutation in the host's genes to trigger disease. The observation may help explain why many people with disease risk genes do not actually develop disease.

16-Jun-2010 9:00 AM EDT
Early-Life Exposure to Polychlorinated Biphenyls Reduces Immune Response to Vaccination
Environmental Health Perspectives (NIEHS)

Children exposed to polychlorinated biphenyls (PCBs) early in life later had a diminished immune response to diphtheria and tetanus vaccinations, according to a study published online June 20 ahead of print in the peer-reviewed journal Environmental Health Perspectives (EHP).

Released: 18-Jun-2010 10:30 AM EDT
SAHM Strongly Recommends Human Papillomavirus Vaccination for 9- to 26-Year-Old Males
Society for Adolescent Health and Medicine

Routine use of HPV vaccine in males provides direct benefits to men and their sexual partners, will increase overall immunization rates among both males and females, and may be cost-effective; SAHM strongly recommends routine use of HPV vaccination in males as well as in females. We urge clinicians and insurance organizations to consider the benefit of routine vaccination for all age-appropriate patients, regardless of gender, in an effort to support the primary prevention of disease among adolescents and adults.

11-Jun-2010 12:05 PM EDT
Maternal, Infant Antiretrovirals Both Effective in Preventing HIV Transmission Through Breast Milk
University of North Carolina Health Care System

The largest study to date to examine methods to prevent HIV infection among breastfeeding infants concludes that giving antiretroviral drugs to HIV-infected breastfeeding mothers in sub-Saharan Africa or giving an HIV-fighting syrup to their babies are both effective.

14-Jun-2010 4:15 PM EDT
Incidence of Malaria Jumps When Amazon Forests Are Cut
University of Wisconsin–Madison

Establishing a firm link between environmental change and human disease has always been an iffy proposition. Now, however, a team of scientists from the University of Wisconsin-Madison, writing in the current (June 16, 2010) online issue of the CDC journal Emerging Infectious Diseases, presents the most enumerated case to date linking increased incidence of malaria to land-use practices in the Amazon.

Released: 16-Jun-2010 10:00 AM EDT
Computer-Aided Influenza Virus Vaccine Created
Stony Brook Medicine

A team of molecular biologists and computer scientists at Stony Brook University have used a novel method to weaken influenza virus by designing hundreds of mutations to its genetic code to create an effective vaccine.

   
14-Jun-2010 4:00 PM EDT
Major Study Examines CF Survival Rates and MRSA Infections
Case Western Reserve University

A team of researchers led by Elliott Dasenbrook, MD, MHS, Assistant Professor of Medicine and Pediatrics at Case Western Reserve School of Medicine and Associate Director of the Adult Cystic Fibrosis Program at University Hospitals Case Medical Center’s Rainbow Babies & Children’s Hospital today published the findings from a major study about cystic fibrosis (CF) survival rates.

15-Jun-2010 9:50 AM EDT
2009 H1N1 Vaccine Protects Against 1918 Influenza Virus; Cross-Protection Helps Alleviate Bioterrorism Concerns
Mount Sinai Health System

Researchers at Mount Sinai School of Medicine have determined people who were vaccinated against the 2009 H1N1 influenza virus may also be protected against the lethal 1918 Spanish influenza virus, which killed more than 50 million people worldwide.

Released: 15-Jun-2010 9:00 AM EDT
How Bacteria Boost the Immune System
Loyola Medicine

Scientists have long known that certain types of bacteria boost the immune system. A new study is showing how bacteria perform this essential task.

Released: 15-Jun-2010 9:00 AM EDT
Vitamin D May Protect Against Influenza and Other Viruses
Greenwich Hospital

Vitamin D may help reduce the incidence and severity of viral respiratory tract infections including influenza, according to a new study conducted by investigators at Greenwich Hospital and Yale University School of Medicine.

Released: 11-Jun-2010 1:00 PM EDT
New Immunizations Guidelines Everyone Should Know
Butler University

Summer is all about barbeques and lazy days at the pool. It’s also a good time to start thinking about preparing for flu season, and the vaccinations you or your child may need for the upcoming year, says Carrie Maffeo, a professor of pharmacy at Butler University, who specializes in immunizations.

Released: 11-Jun-2010 1:00 PM EDT
The Key to Better Infection Control is Better Disinfecting Tools
BioNeutral Group

Currently, disinfecting formulations can take more than 10 minutes after application to eradicate a microorganism, and they are often toxic formulations. The amount of time required for effectiveness and the harm the products inflict on the environment make this an unrealistic and unviable solution to the problem. One scientist may have found an effective alternative.

Released: 11-Jun-2010 1:00 PM EDT
New Progress for HIV/AIDS Therapeutic Vaccine As First Trial Moves Forward
GeoVax Labs

According to Melanie Thompson, Principal Investigator at The AIDS Research Consortium of Atlanta (ARCA). "A vaccine that enhanced the body's ability to control HIV and delayed or decreased the dependence on anti-HIV drugs would be a major breakthrough for HIV treatment."

Released: 11-Jun-2010 1:00 PM EDT
New Grant Supports Development of Antimicrobial Sutures to Combat Infection
PolyMedix

A new discovery may help curb surgical site infections (SSI) through the use of a novel antibiotic agent that can be incorporated into sutures.

Released: 11-Jun-2010 11:30 AM EDT
Directly Observed HIV Treatment by Patient-Nominated Treatment Supporter Improves Survival
Johns Hopkins Bloomberg School of Public Health

Community-based model of directly observed therapy has no effect on virologic outcomes, but significantly improves HIV patient survival.

Released: 10-Jun-2010 9:00 AM EDT
Treatment with Naturally Occuring Protein Prevents and Reverses Brain Damage Caused by Meningitis
Children's Hospital Los Angeles

Studies suggest role for IL-10 in prevention and treatment of potentially devastating neurological disease in newborns.

Released: 9-Jun-2010 2:50 PM EDT
Texas Tech Enters License Agreement for Technology That Combats Antibiotic-Resistant Bacteria
Texas Tech University

When used in conjunction with these antibiotics, the chemical additives overcome enzymes produced by resistant bacteria that allow them to survive exposure to antibiotics.

Released: 9-Jun-2010 12:00 PM EDT
Faculty Tackles Immune System Differences Between the Sexes
Johns Hopkins Bloomberg School of Public Health

Sex Hormones and Immunity to Infection investigates the role biological sex plays in immune responses to infection and the possibility that males and females may differ in their responses to treatments.

4-Jun-2010 5:00 PM EDT
Study Examines ICU Outbreak of Staph Aureus With Resistance to Methicillin and Linezolid
JAMA - Journal of the American Medical Association

An outbreak of infection due to linezolid and methicillin-resistant Staphylococcus aureus (LRSA) in 12 intensive care unit patients in Spain was associated with transmission within the hospital and extensive usage of the antibiotic linezolid, often used for the treatment of serious infections, with reductions in linezolid use and infection-control measures associated with resolution of the outbreak, according to a study in the June 9 issue of JAMA.

Released: 3-Jun-2010 3:00 PM EDT
For Infants with Influenza, Oseltamivir Seems Safe and Effective
Wolters Kluwer Health: Lippincott

Given promptly, the antiviral drug oseltamivir (Tamiflu) appears safe and effective for infants hospitalized with influenza, reports a study in the June issue of The Pediatric Infectious Disease Journal. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health, a leading provider of information and business intelligence for students, professionals, and institutions in medicine, nursing, allied health, and pharmacy.

Released: 2-Jun-2010 12:30 PM EDT
Einstein Awarded NIH Grant to Study Drug-Resistant TB
Albert Einstein College of Medicine

The National Institutes of Health (NIH) has awarded scientists at Albert Einstein College of Medicine of Yeshiva University a five-year, $3.9 million grant to study how extensively drug-resistant tuberculosis (XDR-TB) is transmitted in rural South Africa. The findings could alter public health approaches for controlling the XDR-TB epidemic in the developing world.

Released: 2-Jun-2010 9:00 AM EDT
Headed to Soccer's World Cup in South Africa? Worry About Health Basics, Not Malaria
University of Alabama at Birmingham

A new study shows that travelers to the upcoming World Cup soccer matches in South Africa should focus less on avoiding tropical diseases such as malaria and concentrate more on protecting themselves from more common illnesses – acute diarrhea, sexually transmitted diseases, insect and tick bites, and vaccine-preventable infections, especially influenza and measles. The report is based a 13-year period of GeoSentinel monitoring among travelers to South Africa.

Released: 2-Jun-2010 9:00 AM EDT
Mutant Gene Link to West Nile Virus in Horses
University of Adelaide

The same mutated gene that makes humans more susceptible to the potentially fatal West Nile virus is also responsible for the virus affecting horses, according to scientists at the University of Adelaide.

Released: 1-Jun-2010 4:25 PM EDT
A Third of Young Girls Get HPV Vaccine to Prevent Cervical Cancer
Washington University in St. Louis

Only about one in three young women has received the human papillomavirus (HPV) vaccine to help prevent cervical cancer, according to a new report from researchers at Washington University School of Medicine in St. Louis.

Released: 28-May-2010 4:45 PM EDT
Cold Sore Virus May Contribute to Cognitive and Brain Abnormalities in Schizophrenia
Johns Hopkins Medicine

Exposure to the common virus that causes cold sores may be partially responsible for shrinking regions of the brain and the loss of concentration skills, memory, coordinated movement and dexterity widely seen in patients with schizophrenia, according to research led by Johns Hopkins scientists.

Released: 27-May-2010 5:00 PM EDT
Flu Doesn't Die Out, It Hides Out
University of Michigan

Every autumn, as predictably as falling leaves, flu season descends upon us. Every spring, just as predictably, the season comes to a close. This cyclical pattern, common in temperate regions, is well known, but the driving forces behind it have been in question.

24-May-2010 8:30 AM EDT
Shape Matters: The Corkscrew Twist of H. Pylori Lets It Set Up Shop in the Stomach
Fred Hutchinson Cancer Center

The bacterium Helicobacter pylori, which lives in the human stomach and is associated with ulcers and gastric cancer, is shaped like a corkscrew, or helix. For years researchers have hypothesized that the bacterium’s twisty shape is what enables it to survive – and thrive – within the stomach’s acid-drenched environment, but until now they have had no proof.

Released: 27-May-2010 8:40 AM EDT
Professor Receives NIH Grant to Develop Antibiotics That Can Kill Resistant Tuberculosis Strains
Northeastern University

Northeastern biology professor Kim Lewis has received a three-year $1.16 million grant from the National Institutes of Health to lead the development of new treatments against tuberculosis, a disease that is increasingly resistant to antibiotics, killing nearly two million people worldwide each year.

Released: 25-May-2010 12:00 PM EDT
Researchers Move Closer to a Universal Influenza Vaccine
Mount Sinai Health System

Researchers at Mount Sinai School of Medicine have developed a new influenza vaccine that brings science one step closer to a universal influenza vaccine that would eliminate the need for seasonal flu shots. The new findings can be found in the inaugural issue of mBio®, the first online, open-access journal published by the American Society for Microbiology.



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