Sleep disturbance symptoms are common in major depressive disorder (MDD) and have been found to hamper the treatment effect of conventional face-to-face psychological treatments such as cognitive behavioral therapy. To in...
Many prostate cancer (PC) survivors experience disease and treatment-related symptomatology in both the physical and psychosocial domains. Although the benefits and barriers to using web-based resources for cancer patient...
Baleen plates –the signature bristle-like apparatus toothless whales use to feed – reveal how these large aquatic mammals adapt to environmental changes over time.
The music industry, in little more than twenty years, has gone through two technological shocks linked to digitization: first the advent of downloads, which have replaced physical supports, then that of streaming, with the passage from the possession of a content to the right of access to a catalog.
A Clemson University faculty member collaborating with researchers from Kaiser Permanente Northern California Division of Research, has found that nature’s benefits may include savings on health care costs. The research, published March 17, 2022 in Environment International, suggests health care systems may spend hundreds of dollars less per person per year on medical care for people living in neighborhoods with the most green space than they do on those living near the least trees, shrubs and grass.
Children with complex medical conditions, especially those who require behavioral health treatment, often have to go outside of their insurance plans’ provider networks for care, a new study has found. Almost one in five children with complex, chronic medical conditions such as cystic fibrosis and Type 1 diabetes, who also need behavioral health care, are seen by specialists who are out of network, found the new study, led by researchers at The Ohio State University.
From elaborate dances to stunning plumage displays to dramatic head-butting, male animals have an array of ways to distinguish themselves from competitors while wooing a potential mate. But it’s not their only chance to prove their worthiness. Sexual selection can take place after mating, too, and new research from University of Oregon scientists suggests that it can have a surprisingly large impact on evolution.
Our immune protection is provided by two systems working hand in hand. When infected with a virus, the immune system reacts by producing antibodies that can prevent the virus from infecting further cells.
A new computational approach developed by researchers at The University of Texas MD Anderson Cancer Center successfully combines data from parallel gene-expression profiling methods to create spatial maps of a given tissue at single-cell resolution. The resulting maps can provide unique biological insights into the cancer microenvironment and many other tissue types.
Results from the ZUMA-12 trial led by researchers at The University of Texas
MD Anderson Cancer Center showed that first-line treatment with axicabtagene ciloleucel (axi-cel), a chimeric antigen receptor (CAR) T cell therapy, achieved a high rate of complete response in patients with high-risk large B-cell lymphoma (LBCL). The study was published today in Nature Medicine, and results recently were presented at the 2021 American Society of Hematology (ASH) meeting.
Although allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not always clear.
Efforts to determine the actual size and makeup of the abortion provider workforce in the U.S. often rely on surveys that are limited in scope or else focus solely on abortion facilities. To get more comprehensive pictures of the abortion provider workforce, researchers at the George Washington University combed through a national medical claims data set to examine the workforce providing abortion care and management of pregnancy loss.
Most people would say the COVID-19 pandemic hasn’t been a great couple of years. But for the green industry, like plant nurseries and greenhouses, it’s been a boon. But will the uptick in gardening last once the last coronavirus restrictions are lifted? Probably not to the same extreme levels, according to new research from the University of Georgia. But for some, the introduction to gardening may have been just what they needed to dive into a new hobby.
“Cardihab provides an important option to help overcome barriers to participation in conventional in-person cardiac rehabilitation programs. Patients do not have to travel long distances to attend a program – they complete it from home while under clinical supervision. Cardihab also helps fit in with peoples’ busy work schedules and family commitments, and alleviates cost and time constraints associated with traditional programs. It has been a critical alternative particularly during COVID-19 whereby significant disruptions to traditional programs have been experienced Australia wide, and social distancing requirements presented further barriers to participation.” [Ms Souris]
Evidence-based clinical guidelines on the management of patients on common anticoagulant and antiplatelet therapies during gastrointestinal (GI) bleeding or undergoing elective endoscopy have been published jointly by the American College of Gastroenterology (ACG) and the Canadian Association of Gastroenterology (CAG).
An experiment which could confirm the fifth state of matter in the universe - and change physics as we know it - has been published in a new paper from the University of Portsmouth.
Scientists compared collisions of ruthenium-96 ions with collisions of zirconium-96 ions, which have four fewer protons, expecting to see a greater separation of charged particles emerging from ruthenium collisions because its greater proton number generates a stronger magnetic field. The results instead showed slightly more charge separation in zirconium collisions. This suggests there may be more differences between these two “isobar” nuclei than just their proton numbers.
… Although rates of clinically overt cerebrovascular events associated with TAVR
are reported to be low—particularly in low-risk patients [26]—… on patient population,
study design, and stroke definition. As we treat more and more patients with TAVR …
… quite high risk of procedure-related stroke after TAVR due to the grade 4
thrombus formation in the ascending aorta, treated with TF-TAVR with the Sentinel
CPS insertion. To our knowledge, the usefulness of a filter device insertion prior to …
… What is the role of routine cerebral embolic protection (CEP) with TAVR? Do all
TAVR strokes occur because of intraprocedural catheter manipulations (Figure 7)?
Are there neurological sequalae to the use of the CEP themselves? Can CEP be …
Delivery of Stem Cell Secretome for Therapeutic Applications F Li, J Zhang, K Yi, H Wang, H Wei, HF Chan, Y Tao… - ACS Applied Bio Materials, 2022 … delivery of stem cell secretome deserve more attention. In this review, we first
discuss approaches for the production and characterization of stem cell secretome
and their optimization strategies. Moreover, the up-to-date studies to improve the …
[HTML] Cancer Stem Cell Markers for Urinary Carcinoma P Xia, DH Liu, ZJ Xu, F Ren - Stem Cells International, 2022 … Cancer stem cell (CSC) refers to cancer cells with stem cell properties, that is,
they have the ability of “self-renewal” and “differentiation.” … In this review, cancer
stem cell surface markers and functional markers in urinary system were summarized …
… In contrast, incidence of postprocedural stroke was relatively low in our study (1.8%),
and periprocedural AF was not associated with higher risk of stroke. Risk of stroke
after TAVR can be affected by various factors, including antithrombotic regimens …
Scientists at La Jolla Institute for Immunology (LJI) have found that people with Parkinson's disease have a clear "genetic signature" of the disease in their memory T cells. The scientists hope that targeting these genes may open the door to new Parkinson's treatments and diagnostics.
Background: A critical unmet need for underserved patients with diabetes is regular access to sufficient support for diabetes self-management. Although advances in digital technologies have made way for eHealth applications that prov...
New genetic research from UniSA shows that up to 19 per cent of childhood AML cases are linked to rare genetic changes that may be inherited through family blood lines.
There is no clear genetic etiology or convergent pathophysiology for autism spectrum disorders (ASD). Using induced pluripotent stem cell (iPSC)-derived brain organoids and single-cell transcriptomics, we modeled alterations in the formation of the forebrain between sons with ASD and their unaffected fathers in ten families. Relative to fathers, probands with macrocephaly presented an increase in dorsal cortical plate excitatory neurons (EN-DCP) to the detriment of preplate lineages, whereas normocephalic ASD probands presented an opposite decrease in EN-DCP-related gene expression. Both cohorts converged in a dysregulation of outer radial glia genes related to translation.
Consumer interest and awareness in nicotine pouches – products that contain nicotine but have no tobacco and one of the newest industry products — is growing and they are most popular among younger smokers and those trying to quit, according to a Rutgers research study.
Letrozole and abemaciclib cause tumor shrinkage or stabilization in 75% of patients in phase 2 trial. Approximately 30% of trial participants had their tumors shrink by more than 30%
By incrementally raising the pressure in diamond anvil cell, and periodically blasting it with a laser beam, UNLV scientists observed a sample of water ice make the transition from a known cubic phase, Ice-VII, to a newly discovered intermediate phase, Ice-VIIt, before settling into another known phase, Ice-X.
Nearly 15 years after the discovery of fast radio bursts (FRBs), the origin of the millisecond-long, deep-space cosmic explosions remains a mystery. That may soon change, thanks to the work of an international team of scientists – including UNLV astrophysicist Bing Zhang – which tracked hundreds of the bursts from five different sources and found clues in FRB polarization patterns that may reveal their origin.
Alzheimer’s disease is the most common and best known of the tauopathies, a set of neurodegenerative brain diseases caused by toxic tangles of the protein tau. A study by researchers at Washington University School of Medicine in St. Louis has shown that targeting astrocytes — an inflammatory cell in the brain — reduces tau-related brain damage and inflammation in mice.
Researchers at Texas Biomed and University of Alabama at Birmingham discovered an antibody cocktail against COVID-19 that appears effective against all variants and other coronaviruses. The cocktail has been exclusively licensed to Aridis Pharmaceuticals, which is seeking a manufacturing partner to advance the treatment to human clinical trials.
Does language shape thought? Do the languages we speak affect how we live our lives? These are some of the oldest questions in the cognitive and social sciences, and a handful of high-profile research articles in the social sciences have argued that language systematically affects people’s values, beliefs and behaviors.
Background: Sleep influences moods and mood disorders. Existing methods for tracking the quality of people’s sleep are laborious and obtrusive. If a method were available that would allow effortless and unobtrusive tracking of slee...
Artificial intelligence advances how scientists explore materials. Researchers from Ames Laboratory and Texas A&M University trained a machine-learning (ML) model to assess the stability of rare-earth compounds. The framework they developed builds on current state-of-the-art methods for experimenting with compounds and understanding chemical instabilities.
Scientists have generated an atlas of the cell types present in the white adipose tissue of humans and in mice, allowing them to look at the composition of fat in unprecedented detail.
Tracing the impact of a single protein, Piezo1, Penn researchers found that restoring it in muscles affected by Duchenne muscular dystrophy could improve their ability to heal efficiently
Researchers led by the University of Bristol show that the earliest jaws in the fossil record were caught in a trade-off between maximising their strength and their speed.
Researchers have uncovered new information about how the area of the brain responsible for memory is triggered when the eyes come to rest on a face versus another object or image.