A task force led by researchers at the Byrd Polar and Climate Research Center at The Ohio State University has released a draft action plan to help central Ohio prepare for climate change.
Case Western Reserve and Cleveland Clinic are leading development of a computerized tissue-imaging program that could soon help identify which lung cancer patients are likely to face an earlier recurrence of the disease.
Biomedical engineers at Case Western Reserve University in Cleveland, Ohio, and Worcester Polytechnic Institute in Worcester, Mass. are growing tracheas by coaxing cells to form three distinct tissue types after assembling them into a tube structure-without relying on scaffolding strategies currently being investigated by other groups.
When people eat at home, there’s typically not much left on their plates – and that means there’s likely less going to landfills, according to new research from The Ohio State University.
In findings that one day may help people sleep better, scientists have uncovered the first molecular evidence that two anciently conserved proteins in the brains of insects and mammals share a common biological ancestry as regulators of body temperature rhythms crucial to metabolism and sleep. Researchers publish their data in the journal Genes & Development.
Exercise has numerous, well-documented health benefits. Could it also play a role in preventing and reducing substance misuse and abuse in adolescents? This is the intriguing question that a team of investigators from Case Western Reserve University School of Medicine and Cleveland Clinic seeks to answer. In a review article recently published in Birth Defects Research, the trio of researchers supplies a rationale for the use of exercise, particularly assisted exercise, in the prevention and adjunctive treatment of substance-use disorders – including alcohol, marijuana, cocaine, opioids, and heroin.
Korie Edwards, associate professor of sociology at The Ohio State University, talks about how race and power structures are perceived in churches, and also how religion plays a role among youth.
Genomic profiling of mostly untreatable and deadly nerve sheath tumors led scientists to test a possible therapeutic strategy that inhibited tumor growth in lab tests on human tumor cells and mouse models, according to research in the journal Cancer Cell.
When it comes to heart health emergencies, many Americans don’t have the knowledge to aid others, and often don’t know the proper way to help themselves, according to a new Cleveland Clinic survey.
The survey found that slightly more than half of Americans (54 percent) say they know how to perform CPR; however, only one in six know that the recommended technique for bystander CPR consists of just chest compressions – and no breaths – on an adult. Even fewer, 11 percent, know the correct pace for performing these compressions (100 to 120 beats per minute).
In one of the first successes of its kind, researchers have inhibited the spreading of cancer cells from one part of the body to another. In doing so, they relied on a new model of how cancer metastasizes that emphasizes epigenetics, which examines how genes are turned on and off.
When the body attacks its own healthy tissues in an autoimmune disease, peripheral nerve damage handicaps people and causes persistent neuropathic pain when insulation on healing nerves doesn’t fully regenerate. Unfortunately, there are no effective ways to treat the condition. Now scientists describe in Nature Medicine an experimental molecular therapy that restores insulation on peripheral nerves in mice, improves limb function, and results in less observable discomfort.
A study of four medical marijuana outlets in California suggests that many of their customers don’t fit the profile expected for businesses focused on sick patients.
More people are walking away from a type of cardiac arrest that is nearly always fatal, thanks to a new protocol being tested at The Ohio State University Wexner Medical Center. It’s called an ECPR alert.
Researchers used 3D imaging with molecular testing to uncover new insight into the earliest stages of mammalian pregnancy—offering clues to unsolved questions in pregnancy. Investigators report Feb. 9 in Nature Communications they demonstrated in mice that glands in the uterus must link and communicate directly with the embryo so it will implant and begin pregnancy.
Cleveland Clinic researchers have published findings in Nature Communications on a new stem cell pathway that allows a highly aggressive form of breast cancer - triple-negative breast cancer - to thrive.
Before medical science can bioengineer human organs in a lab for therapeutic use, two remaining hurdles are ensuring genetic stability—so the organs are free from the risk of tumor growth—and producing organ tissues of sufficient volume and size for viable transplant into people. Scientists report in Stem Cell Reports achieving both goals with a new production method for bioengineered human gut and liver tissues.
A research team at Case Western Reserve is asking an important question about the self-evident paradox standing in the way of our generally accepted theory of how the Earth's inner core formed. The "inner core nucleation paradox" suggests that there is now satisfactory solution to account for the existence of a solid inner core. So, now what?
Dr. Sandra Faulkner’s new book, “Real Women Run: Running as Feminist Embodiment,” brings poetic inquiry, ethnography and feminist analysis to the study of women runners of all identities and how they fit or do not fit cultural expectations. Faulkner makes the case for a more physical feminism.
A team of researchers from Case Western Reserve University School of Medicine have used Nobel prize-winning microscope technology to see full length serotonin receptors for the first time. The tiny proteins—approximately a billionth of a meter long—are common drug targets, despite limited available information about their structure. Now, new images published in Nature Communications provide snapshots of the receptors, including details about molecular binding sites that could lead to more precise drug design.