Strokes rates are high among African Americans, but concerns about medical cost, ambulance response time and unfamiliarity with the need for prompt hospital care impacted whether they called 9-1-1 immediately.
As part of a new personalized medicine initiative, the University of Maryland Medical Center is offering genetic testing to help doctors determine which medication a patient should take after a stenting procedure in order to prevent blood clots that could lead to serious – and potentially fatal – heart attacks and strokes.
Total anomalous pulmonary venous connection, one type of “blue baby” syndrome, is a potentially deadly congenital disorder that occurs when pulmonary veins don’t connect normally to the left atrium of the heart. TAPVC babies are born cyanotic from lack of oxygen. Semaphorin 3d guides the development of endothelial cells and is crucial for normal development of pulmonary veins. Mutations in Sema3d cause embryonic blood vessels to hook up in the wrong way.
Programming an implantable cardioverter-defibrillator (ICD) with a long-detection interval compared with a standard-detection interval resulted in a reduction in anti-tachycardia pacing episodes, ICD shocks delivered, and inappropriate shocks, according to a study in the May 8 issue of JAMA.
A study appearing in the Journal of Nutritional Biochemistry demonstrates that grapes are able to reduce heart failure associated with hypertension by increasing the activity of several genes responsible for antioxidant defense in the heart tissue.
When teenage girls are exposed to secondhand smoke at home, they tend to have lower levels of the “good” form of cholesterol that reduces heart disease risk, according to a recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
Researchers claim to have calculated for the first time, the upper safe limit of vitamin D levels, above which the associated risk for cardiovascular events or death raises significantly, according to a recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
Your genetic makeup can help determine how well your body will respond to weight loss efforts aimed at controlling high blood pressure, a new study confirms. The multi-institutional study, led by researchers at The Cardiovascular Institute, part of the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, may help clarify how hypertension develops and progresses in certain individuals and also identify people for whom weight loss programs are most likely to help reduce blood pressure.
Researchers at Washington University School of Medicine in St. Louis have described a missing link in understanding how damage to the body’s cellular power plants leads to Parkinson’s disease and, perhaps surprisingly, to some forms of heart failure.
Using a one-of-a-kind computer-aided program, Mayo Clinic has developed and implemented a Mayo-wide electronic warning system to identify patients at risk of QT-related deaths from an abnormality in the heart’s electrical system. The system informs all physicians, regardless of their specialty or QT awareness, if their patient’s ECG activated the QT alarm. In addition, the researchers discovered that the death rate of patients whose 12-lead electrocardiogram (ECG) activated the QT alert was nearly four times greater than all other patients who had an ECG. The findings are published in the current issue of Mayo Clinic Proceedings.
Long-term exposure to air pollution may be linked to heart attacks and strokes by speeding up atherosclerosis, or "hardening of the arteries," according to a University of Michigan public health researcher and colleagues from across the U.S.
Consuming grapes may help protect against organ damage associated with the progression of metabolic syndrome, according to research presented this week at the Experimental Biology conference in Boston.
Hair strands contain valuable information about senior citizens’ stress levels that can be used to determine an individual’s cardiovascular disease risk, according to a recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
A new study by University of North Carolina School of Medicine researchers finds that patients who suffer a STEMI heart attack while hospitalized are 10 times more likely to die than patients who suffer a STEMI outside the hospital.
A common test that records the heart’s electrical activity could predict potentially serious cardiovascular illness, according to a UC San Francisco-led study.
New finding in European Heart Journal contradicts recent study in the same publication; suggests evidence is lacking that digoxin increases mortality as a treatment for atrial fibrillation.
Researchers at the University of Michigan have identified a new potential therapeutic target for lowering cholesterol that could be an alternative or complementary therapy to statins.
Translating a Mayo Clinic stem-cell discovery, an international team has demonstrated that therapy with cardiopoietic (cardiogenically-instructed) or “smart” stem cells can improve heart health for people suffering from heart failure. This is the first application in patients of lineage-guided stem cells for targeted regeneration of a failing organ, paving the way to development of next generation regenerative medicine solutions. Results of the clinical trial appear online of the Journal of the American College of Cardiology.
Mayo Clinic physicians in Arizona have shown that tablet computers can be used to analyze electroencephalogram or EEG results outside of the clinic or hospital. Their study findings were recently presented at the American Academy of Neurology conference in San Diego.
A UCLA study shows that heart failure medications recommended by national guidelines are highly cost effective in saving lives and may also provide savings to the health care system.
Certified Primary Stroke Centers are three times more likely to administer clot-busting treatment for strokes than non-certified centers, reports a new study by researchers in the Perelman School of Medicine at the University of Pennsylvania.
In what promises to be an eye-opener for many doctors and patients who routinely depend on cholesterol testing, a study led by researchers at the Johns Hopkins University School of Medicine found that the standard formula used for decades to calculate low-density lipoprotein (LDL) cholesterol levels is often inaccurate. Of most concern, the researchers say, is their finding that the widely used formula underestimates LDL where accuracy matters most — in the range considered desirable for high-risk patients. Results of the study are published in an online article, ahead of print, in the Journal of the American College of Cardiology.
UCLA researchers have genetically engineered tomatoes to produce a peptide that mimics the actions of good cholesterol when consumed. In this early study, mice that were fed these tomatoes in freeze-dried, ground form had less inflammation and plaque build-up in their arteries.
A new study in the March 2013 Women’s Health Issues evaluates the Heart Truth educational campaign on provider knowledge of heart disease as it affects women. The team of researchers studied the delivery of The Heart Truth® Professional Education Campaign across three states to diverse audiences of healthcare providers. All of the healthcare providers showed improved knowledge on women and heart disease after participating in the lectures.
For the first time, a UCLA team has used a technique normally employed in treating brain aneurysms to treat severe, life-threatening irregular heart rhythms in two patients.
Millions of Americans take drugs to reduce their risk of heart attacks caused by blood clots. A new study suggests that a fear of brain bleeding if these patients receive stroke therapy may be unfounded, at least for most patients taking common clot-preventing therapies.
A single dose of an investigational anti-inflammatory drug called inclacumab considerably reduces damage to heart muscle during angioplasty (the opening of a blocked artery), according to a recent international clinical trial spearheaded by Dr. Jean-Claude Tardif, Director of the Research Centre at the Montreal Heart Institute, affiliated with the University of Montreal.
While two large clinical trials recently showed that adding niacin to statin therapy failed to improve clinical outcomes despite a significant increase in HDL-C levels, little is known about exactly why the increased HDL-C levels did not reduce the risk of cardiovascular events, including heart attack and stroke. Now, a small study from researchers the Perelman School of Medicine at the University of Pennsylvania, has shown that while niacin increased measured levels of HDL-C, it did not improve the functionality of HDL. This may provide an explanation for the failure of niacin to further reduce cardiovascular risk. The study results were reported today at the 62nd Annual Scientific Session of the American College of Cardiology in San Francisco.
New research from a multidisciplinary team at the Perelman School of Medicine at the University of Pennsylvania has shown that the combination of CPAP and weight loss for patients with OSA can help lower blood pressure better than either therapy alone. The study results were reported today at the 62nd Annual Scientific Session of the American College of Cardiology in San Francisco.
Researchers show how fish oils help lower blood pressure via vasodilation at ion channels. In vascular smooth muscle cells, such as those that line blood vessels, ion channels that span the outer membrane of a cell to let such ions as sodium, calcium, and potassium in and out, are critical to maintaining proper vessel pressure.
A study that analyzed data from more than 82,000 veterans suggests that infection with the human immunodeficiency virus (HIV) was associated with an increased risk of acute myocardial infarction (AMI, heart attack) beyond what is explained by recognized risk factors, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication.
As most people know, there are many differences between men and women (to say the least). But what if acknowledging those differences could save a life.
A treatment that's similar to kidney dialysis is removing cholesterol from the blood of patients who cannot control cholesterol through diet, exercise and medications.
An abdominal aortic aneurysm — a bulge in the large artery that carries blood away from the heart — can be immediately life-threatening if it grows large enough to rupture. The chance of survival when it ruptures is less than 10 percent.
Many who find out they have that risk are able to have a minimally invasive repair. But up to 30 percent instead face a major open operation because of the location of the aneurysm. This new customized graft allows them, too, to have a quick recovery.
Even after successful treatment, patients with Cushing’s disease who were older when diagnosed or had prolonged exposure to excess cortisol face a greater risk of dying or developing cardiovascular disease, according to a recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).
Researchers have found a genetic variant that doubles the likelihood that people will have calcium deposits on their aortic valve. Such calcification, if it becomes severe, can cause narrowing or a blockage of the aortic valve, a condition called aortic stenosis. The study is the first large-scale, genome-wide association study to uncover a genetic link to aortic valve calcification. An article detailing the findings is published in the February 7, 2013 issue of The New England Journal of Medicine.
Although heart disease remains the No. 1 killer nationally for women—responsible for one out of every three deaths—many of today’s women still underestimate the seriousness of the disease and their risks, says Liliana Cohen, MD, a board-certified cardiologist with The Robert Wood Johnson Medical Group.