The research may also advance understanding of the biochemical roots of Parkinson’s disease and other synucleinopathies, which affect more than 6.8 million Americans.
People who have had a heart attack may be slightly less likely than people in the general population to develop Parkinson’s disease later in life, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.
ISU researchers are embarking on an in-depth and comprehensive study to determine the underlying mechanisms by which singing can improve breathing and swallowing for people with Parkinson’s disease. The researchers will also track changes to brain activity and biomarkers of stress and inflammation to better understand how the social benefits of singing with others can slow the disease’s progression and its symptoms.
A five-year, $3.2 million grant from the National Institutes of Health will help a research team including faculty at Binghamton University, State University of New York explore serotonin's role in Parkinson's disease.
University of Maryland School of Medicine researchers developed a technique in laboratory animals to consistently and reproducibly open the blood-brain barrier. Their paper essentially provides a roadmap for other researchers to develop and test new therapies for brain diseases.
A new study shows that people with Parkinson’s disease who eat a diet that includes three or more servings per week of foods high in flavonoids, like tea, apples, berries and red wine, may have a lower chance of dying during the study period than people who do not eat as many flavonoids. The research is published in the January 26, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study looked at several types of flavonoids and found that higher consumption of flavan-3-ols and anthocyanins, both before and after a Parkinson’s diagnosis, was associated with lower risk of death during the study period.
New pose estimation software has the potential to help neurologists and their patients capture important clinical data using simple tools such as smartphones and tablets, according to a study by Johns Hopkins Medicine...
Researchers in a multi-institution study led by UCLA Health call for more research as well as customized treatments, education and support to empower women living with Parkinson’s disease to address their unmet medical needs.
Irvine, Calif., Jan. 19, 2022 — A team of University of California, Irvine researchers has discovered a possible reason why L-dopa, the front-line drug for treating Parkinson’s disease, loses efficacy and causes dyskinesia – involuntary, erratic muscle movements of the patient’s face, arms, legs and torso – as treatment progresses.
CLEVELAND: Cleveland Clinic has launched a landmark study to better understand why millions of people around the world suffer from brain diseases, with the goal of pinpointing disease biomarkers early, well before clinical symptoms present themselves.
The new Cleveland Clinic Brain Study – the largest clinical study ever for brain disease – will collect data from up to 200,000 neurologically healthy individuals over a 20-year period to identify brain disease biomarkers and targets for preventing and curing neurological disorders.
A new study suggests that people with early-stage Parkinson’s disease who regularly got one to two hours of moderate exercise twice a week, like walking or gardening, may have less trouble balancing, walking and doing daily activities later. The research is published in the January 12, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers found that those who exercised regularly over five years did better on cognitive tests and had slower progression of the disease in several aspects.
Mount Sinai researchers analyzed thousands of microglia from different brain regions of deceased patients who had been diagnosed with a variety of neuropsychiatric and neurodegenerative disorders. Their results, published in Nature Genetics, support the idea that microglia may play critical roles in some cases of brain disease while also providing a potentially valuable guide for future studies.
Researchers reporting in ACS Chemical Neuroscience have shown that, at least in the test tube, the SARS-CoV-2 N-protein interacts with a neuronal protein called α-synuclein and speeds the formation of amyloid fibrils, pathological protein bundles that have been implicated in Parkinson’s disease.
UC San Diego School of Medicine partners with The Michael J. Fox Foundation on a clinical study to identify biomarkers of Parkinson’s disease. The study seeks to recruit 4,000 participants by the end of 2023.