A missing brain enzyme increases concentrations of a protein related to pain-killer addiction, according to an animal study. The results will be presented Monday at The Endocrine Society’s 95th Annual Meeting in San Francisco.
Scientists at The Scripps Research Institute have found evidence that an emotion-related brain region called the central amygdala—whose activity promotes feelings of malaise and unhappiness—plays a major role in sustaining cocaine addiction.
New findings provide vital step towards exploring pain medications that may lower risks of prescription drug abuse and side effects of painkillers.
The last few years have seen the emergence of a new drug problem in so-called "bath salts"—actually "designer stimulants," packaged and sold in ways that skirt drug laws. A review and update on these designer drugs is presented in the June Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
Researchers at Johns Hopkins have unraveled the molecular foundations of cocaine’s effects on the brain, and identified a compound that blocks cravings for the drug in cocaine-addicted mice. The compound, already proven safe for humans, is undergoing further animal testing in preparation for possible clinical trials in cocaine addicts, the researchers say.
The offspring of parents who were addicted to drugs or alcohol are more likely to be depressed in adulthood, according to a new study by University of Toronto researchers. In a paper published online in the journal Psychiatry Research this month, investigators examined the association between parental addictions and adult depression in a representative sample of 6,268 adults, drawn from the 2005 Canadian Community Health Survey. Of these respondents, 312 had a major depressive episode within the year preceding the survey and 877 reported that while they were under the age of 18 and still living at home that at least one parent who drank or used drugs “so often that it caused problems for the family”.
St. Louis College of Pharmacy, the city of St. Louis, and U.S. Drug Enforcement Administration collaborate to collect unwanted and expired medicine. This year, the result was more than 16,000 pounds collected.
Nationwide, only one in ten people with substance abuse disorders receive medical intervention, opposed to nearly 90% of those with diabetes – a problem that becomes exponentially worse in the Appalachian region, where deaths from prescription drug overdoses have jumped 360% in the last decade. Experts gathered at the Fourth Annual Scientific Meeting of The Ohio State University Center for Clinical and Translational Science (CCTS), to share ideas and examples to help reverse the deadly substance abuse trends that are further complicated by health disparities, social and economic issues unique to a region that spans 13 states.
Scientists at The Scripps Research Institute (TSRI) have reported successful preclinical tests of a new vaccine against heroin. The vaccine targets heroin and its psychoactive breakdown products in the bloodstream, preventing them from reaching the brain.
A study of adolescents receiving treatment for methamphetamine dependence has found that girls are more likely to continue using the drug during treatment than boys, suggesting that new approaches are needed for treating meth abuse among teen girls.
Research from the University of Adelaide suggests that mothers who eat junk food while pregnant have already programmed their babies to be addicted to a high fat, high sugar diet by the time they are weaned.
Young adults reduce their overall prescription drug misuse up to 65 percent if they are part of a community-based prevention effort while still in middle school, according to researchers at Iowa State University.
Police say prescription medication is often a gateway to narcotics like heroin. Remove potentially harmful medication from your home this weekend.
By stimulating one part of the brain with laser light, researchers at the National Institutes of Health (NIH) and the Ernest Gallo Clinic and Research Center at UC San Francisco (UCSF) have shown that they can wipe away addictive behavior in rats – or conversely turn non-addicted rats into compulsive cocaine seekers.
Data from a statewide survey of sixth-, eighth-, and 11th-grade Iowa students found an increased risk for alcohol use, binge drinking, and using marijuana and other illegal drugs, among children of deployed or recently returned military parents compared to children in non-military families.
A Wake Forest Baptist Medical Center team studying alcohol addiction has new research that might shed light on why some drinkers are more susceptible to addiction than others.
New research from the University of North Carolina School of Medicine for the first time explains exactly how two brain regions interact to promote emotionally motivated behaviors associated with anxiety and reward. The findings could lead to new mental health therapies for disorders such as addiction, anxiety, and depression.
Abuse of the anesthesia drug propofol is a "rapidly progressive form of substance dependence" that is being more commonly seen among health care professionals, reports a study in the April Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
A Case Western Reserve University professor has found that young people addicted to alcohol and drugs can increase their chances of recovery by helping others. In a study of nearly 200 juvenile offenders, Maria Pagano, PhD, found that youth who became active in AA-related helping (AAH) during treatment were less likely to test positive for alcohol and drugs during treatment and had greater psychosocial improvement.
Study shows striking demographic shift in hospital admissions due to prescription opiate and heroin-related overdoses, 1993-2009.
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