Scientists at the University of Chicago, Harvard, and China have described the surprising discovery and function of a new DNA modification in insects, worms, and algae.
ORNL scientists combined atomic force microscopy and mass spectrometry into one instrument that can probe a polymer sample in three dimensions and overlay information about the topography of its surface, the atomic-scale mechanical behavior of the bulk sample, and subsurface chemistry. Their results are published in ACS Nano.
Scientists at the Department of Energy’s SLAC National Accelerator Laboratory and Utrecht University have identified key mechanisms of the aging process of catalyst particles that are used to refine crude oil into gasoline. This advance could lead to more efficient gasoline production.
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Chemists funded by NIH are working to develop “greener” processes for discovering, developing and manufacturing medicines and other molecules with therapeutic potential, as well as compounds used in biomedical research. Organic chemist Bob Lees describes some of these efforts.
The lab of Kristen Lynch, PhD studies how this splicing occurs in T cells and how it is regulated by multiple proteins. A new study describes a cascade of events that may explain changes in gene expression that occur during the development of the human immune system.
In a move that could improve the energy storage of everything from portable electronics to electric microgrids, University of Wisconsin–Madison and Brookhaven National Laboratory researchers have developed a novel X-ray imaging technique to visualize and study the electrochemical reactions in lithium-ion rechargeable batteries containing a new type of material, iron fluoride.
Research teams led by Edward Yu of Iowa State University and the Ames Laboratory have described the structure of two closely related protein pumps that allow bacteria to resist certain medications.
University at Buffalo researchers have discovered a way to easily and effectively fasten proteins to nanoparticles – essentially an arranged marriage – by simply mixing them together. The biotechnology, described April 20 online in the journal Nature Chemistry, is in its infancy. But it already has shown promise for developing an HIV vaccine and as a way to target cancer cells.
A new mathematical model that uses drug-target kinetics to predict how drugs work in vivo may provide a foundation to improve drug discovery, which is frequently hampered by the inability to predict effective doses of drugs. The discovery by Peter Tonge, a Professor of Chemistry and Radiology, and Director of Infectious Disease Research at the Institute for Chemical Biology and Drug Discovery (ICB & DD) at Stony Brook University, along with collaborators at Stony Brook University and AstraZeneca, will be published advanced online on April 20 in Nature Chemical Biology.
Climate models calculate a changing mix of clouds and emissions that interact with solar energy. To narrow the broad range of possible answers from a climate model, researchers analyzed the effect of several proven numerical stand-ins for atmospheric processes on the energy flux at the top of the atmosphere. They found that the flux is the main driver of surface temperature change.
By combining biocompatible light-capturing nanowire arrays with select bacterial populations, a potentially game-changing new artificial photosynthesis system offers a win/win situation for the environment: solar-powered green chemistry using sequestered carbon dioxide.
A little-known element called californium is making big waves in how scientists look at the periodic table. According to new research by a Florida State University professor, californium is what’s known to be a transitional element, meaning it links one part of the Periodic Table of Elements to the next.
Neuroscientists at NYU Langone Medical Center have discovered how the powerful brain hormone oxytocin acts on individual brain cells to prompt specific social behaviors – findings that could lead to a better understanding of how oxytocin and other hormones could be used to treat behavioral problems resulting from disease or trauma to the brain.
A new breakthrough battery—one that has significantly higher energy, lasts longer, and is cheaper and safer—will likely be impossible without a new material discovery. And a new material discovery could take years, if not decades, since trial and error has been the best available approach. But Lawrence Berkeley National Laboratory scientist Kristin Persson says she can take some of the guesswork out of the discovery process with her Electrolyte Genome.
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