Newswise — Going on 20 years, the expertise of DIARECT AG is the design, manufacture and sales of recombinant and native antigens to the global IVD market.

We provide our customers with over 150 antigens, and our product range is constantly expanding. The major product lines are:

  • Recombinant Allergens, food- and aeroallergens
  • Autoimmune Antigens and corresponding Monoclonal Human Chimeric Antibodies, for use as positive controls and calibrators
  • Infectious Disease Antigens, mainly for tick-borne disease diagnostics

Our products are all produced and tested using strict guidelines to ensure high quality, lot-to-lot consistency and therefore distinguished performance in various diagnostic applications.

To meet today’s requirements for assay development, we recently launched a set of Biotinylated Autoantigens. Some second-generation ELISA technologies, e.g. bead-based arrays, use biotinylated antigens and subsequent conjugation to streptavidin-coated surfaces/beads. Using this approach the strength of attachment of antigens to the base is increased, which results in higher assay sensitivities.

Bead-based technologies for in-vitro diagnostics provide several advantages compared to traditional single protein measurement techniques, including:

  • high sensitivity
  • low sample volume
  • lower costs
  • rapid turnover while generating reproducible data
  • ease of performance
  • elimination of the need for trained personnel and specialized procedures

For this purpose we provide several of our autoimmune antigens in a biotinylated form and more are under development.

To get an overview of all our products, including the antigens to be presented at this year’s AACC, please visit our website at



DIARECT AG was established in 1998 and is listed at the FDA as manufacturer of human recombinant antigens for autoimmune testing. Our area of expertise lies in the development, large-scale production and worldwide distribution of recombinant and native antigens for autoimmune diagnostics. Additionally, our product portfolio includes antigens for allergy diagnostics and infectious serology, mainly focused on tick-borne diseases. The newest product line, biotinylated antigens includes several recombinant and non-recombinant autoimmune antigens. Providing our customers with products and services of constantly high quality, to improve the life of patients worldwide is our philosophy. Therefore, we have implemented Quality Management Systems that are certified for compliance with ISO 9001 and 13485 standards.

Our antigens undergo a rigorous series of tests in our quality control lab. Each lot is subjected to various biochemical and immunological analyses to assure conformance to strict product specifications. This guarantees consistent results, reduces assay development time and increases the productivity of our customers. Product and customer specific service is our trademark to improve and help you finding the best way to improve your assay development and/or research application.

For questions or additional information please feel free to contact us at:
Tel: +49 761 47979-0
Email: [email protected]