An operation developed at Johns Hopkins to halt blinding retinal damage from age-related macular degeneration improved vision in nearly half of the first 100 patients treated, according to a recent report in the American Journal of Ophthalmology.
Millennium Pharmaceuticals, Inc. announced the presentation of preclinical and clinical study results demonstrating that an investigational proteasome inhibitor, LDP-341(formerly PS-341), the first in a new class of anti-cancer agents, is active against multiple myeloma.
Researchers from Dana-Farber Cancer Institute and Harvard Medical School presented data results of Hematology on laboratory studies evaluating the activity of Celgene's IMiDs on multiple myeloma cells. The five abstracts presented suggest that IMiDs may be beneficial in the treatment of multiple myeloma.
In the first study of its kind to include "baby boomers" in its results, researchers predicted demand for medical services provided by critical care and pulmonary specialists will outpace the future supply of these doctors by 2007. (JAMA, 12-6-00)
Substituting margarine for butter reduces "bad" cholesterol - called low-density lipoproteins (LDL) - in adults and children, according to researchers at UT Southwestern Medical Center at Dallas. (JAMA, 12-5-00)
A radioactive compound used for decades to find cancer is now showing surprising promise in helping to kill those tumors too. All 11 children treated for neuroblastoma in the drug's first clinical test initially had a positive response with no significant side effects.
Forty-six abstracts studying thalidomide in hematological disorders were published at the 42nd Annual American Society of Hematology Meeting, December 4, 2000.
A new study published in the Annals of Neurology shows that treatment with interferon beta-1a, or Avonex, has a significant beneficial effect on the cognitive impairment often suffered by people with relapsing multiple sclerosis (MS).
Osteoporosis isnÃt the only reason that some people have weak bones. PagetÃs disease can cause affected bones to become deformed and more likely to break, according to the December issue of Mayo Clinic Health Letter.
People with total cholesterol levels exceeding 240 could benefit substantially by eating 25 to 50 grams of soy protein daily, according to a scientific advisory directed to health-care professionals across the United States. (Circulation)
Emory University researchers have identified more than 400 human genes that are affected by long-term cocaine abuse. The discovery represents the first molecular profile, or fingerprint, for human drug addiction and ultimately could lead to new treatments for addiction.
The new year awaits, but many senior citizens, along with their younger counterparts, have given up on any resolution to start an exercise program. Or maybe they gave up years ago, intimidated by what they thought was required, and now assume itÃs too late. (Quest, 11-00)
Estrogen ñ even in men ñ may join food indulgence and lack of exercise as factors affecting obesity, researchers on two continents say. (Proceedings of the National Academy of Sciences, 11-7-00)
Comprehensive web site presents accumulated resources of leading drug information and global medical publisher, Wolters Kluwer International Health & Science.
A test commonly used to screen newborns' hearing may give false positives in up to a third of cases, causing new parents needless worry and costing more in the long run. But a slightly more complex test gives normal-hearing babies a passing grade nearly all the time. (American Journal of Audiology, 12-00)
Definity Health (formerly HealtheCare), which this fall launched a new consumer-driven health benefit, announced today that it has signed an agreement with Johns Hopkins University and Health System that will provide Definity Health members access to the academic center's extensive consumer health and wellness resources.
Feel a cold coming on? Extra rest and plenty of warm fluids are still the best ways to cope with the common cold, according to the December issue of Mayo Clinic Health Letter. While thereÃs hope that something will be discovered to cure the cold, researchers havenÃt found it yet.
Clineguide, proven effective by physicians and hospital administrators, premiers at eHealthcare World.
Many women (and men) can benefit from calcium supplements to their diets. The December issue of Mayo Clinic Health Letter offers these tips to make sure you are getting the most from calcium supplements.
How well a pneumonia vaccination will protect elderly Americans may depend on how stressed they are when they get the shots. A new Ohio State study is showing that even after six months, the vaccine may have been weakened by a person's stress levels. (Psychosomatic Medicine)
A Children's Hospital Medical Center of Cincinnati study indicates that most efforts to prevent obesity in childhood aren't likely to be successful. The study shows that only 21 percent of mothers of overweight preschoolers feel their children are overweight.
Incorporating Internet-based telemedicine technologies into the care of a very low birth weight infant results in greater family satisfaction with the care and may reduce the infant's length of hospitalization, per a Beth Israel Deaconess Medical Center study.
A University of Michigan researcher has made a surprising discovery that will make blood plasma transfusions even safer. This study will ensure that human parvovirus B19 is not transmitted through the donor plasma supply, potentially causing harmful effects in some patients.
For the first time, scientists at the University of North Carolina at Chapel Hill have used a gene-therapy technique in animals to continually produce very high amounts of a clotting protein similar to that lacking in people with hemophilia. (Molecular Therapy, 12-4-00)
An experimental targeted therapy for chronic myelogenous leukemia continues to show promise in early testing, and it may help to battle the disease even at its most aggressive and deadly stage, according to a researcher at UCLA's Jonsson Cancer Center.
People who suffer from high cholesterol tend to move oxygen from red blood cells to the tissues inefficiently, University of Minnesota surgeon Dr. Henry Buchwald reports. High amounts of cholesterol in red cell membranes is the likely culprit.
Chronic pain and addiction are complex phenomena, and there has been little effort in the medical community to understand the relationship between the two.
Holiday revelers would do well to note that most children who die in alcohol-related vehicle crashes are killed because they are not restrained.
Ever wonder why hunters make such dramatic fashion statements with the color orange?
Researchers at the University of Maryland schools of medicine and pharmacy found that anti-fever drugs such as aspirin and acetaminophen may prolong influenza A infections. (Pharmacotherapy, 12-00)
A top orthopedic surgeon at the University of Mississippi Medical Center performs a restorative hip surgery offered at few U.S. medical centers. The pioneering bone graft surgery gives the patient more mobility and lasts longer than artificial hip replacement.
Antex Biologics Inc. announced that it has filed patent applications for two additional novel proteins of Chlamydia trachomatis, the leading sexually transmitted disease in the US and worldwide. These two proteins are being evaluated as vaccine candidates.
In response to concerns over the safe use of a key treatment for severe cystic acne, the American Academy of Dermatology recently issued a new policy statement on isotretinoin, also known as Accutane.
Psychiatry debunks the commonly held notion that about 15 percent of people diagnosed with depression will commit suicide. (American Journal of Psychiatry, 12-00)
Adding spirulina to cultured immune system cells significantly increases the production of infection fighting cytokines, say immunologists at UC Davis School of Medicine and Medical Center. (Journal of Medicinal Foods)
Proponents of consumer drug ads say the promotions do more than sell pills, they also help educate people about medical conditions and treatments. But the controversial ads actually teach very little, according to a new analysis by researchers at UC Davis and UCLA. (The Journal of Family Practice, 12-00)
On-the-job stress doesn't just strain the nerves -- it can strain the back, too. That's the implication of a study at Ohio State University that provides the first-ever link between stress and back pain. (Spine, 12-1-00)
A 7-year-old patient with autism was found to have a chromosome with deleted segments of DNA. The segments are likely to contain genes that help determine susceptibility to the disorder, according to a study by a UC Irvine College of Medicine research team. (American Journal of Medical Genetics, 12-4-00)
Scientists at Johns Hopkins have developed a gene therapy that, within a week, quells abnormal rhythms in pig hearts, the animal hearts most similar to human. It's believed to be the first use of gene therapy for cardiac arrhythmias, the researchers say, and one with "a strong possibility" of transfer to human heart disease. (Nature Medicine, 12-00)
Researchers may have identified a new marker to spot individuals at risk of a first stroke. (Stroke, 12-00)
Researchers say bone marrow cells transplanted into the brain could be a source of neurons to replace those damaged or lost in neurological disorders. (Science, 12-1-00)
Stanford researchers have shown for the first time that adult bone marrow cells can migrate to the brain, express neuronal-specific proteins and begin to look like their neuronal neighbors. (Science, 12-1-00)
Nearly half of the school nurses surveyed for a recent University of Iowa study reported medication errors in their schools in the past year. The most common error was a missed dose. The findings are contained in a study led by associate professor of nursing at the UI. (Journal of School Health, 11-00)
Senior citizens might be a lot happier -- not to say healthier and maybe even a little wealthier -- if health-care providers and insurers stopped focusing exclusively on costs of prescriptions and instead looked closely at why patients take so many medications in the first place.
Human clinical trials are under way on an innovative peptide-based therapy developed at The University of Arizona College of Medicine that researchers hope will allow people infected with HIV to maintain good health without ever developing the symptoms associated with AIDS.
A new laser eye treatment at the University of Mississippi Medical Center benefits people who are farsighted with astigmatism. That's one-fourth of the visually impaired public. One of the first physicians in the nation to perform LASIK - began performing the corrective surgery Nov. 21.
The Cancer Information Service of New York was recently awarded one of four grants totaling $932,000 from the National Cancer Institute to improve awareness of and access to Internet-based cancer information in minority communities throughout the country.
There is a strong push to find methods that may improve survival of Lung cancer by diagnosing the disease at an earlier, presumably more curable, stage. However, whether early detection results in a higher number of cured patients remains unclear. (NEJM, 11-30-00)
Intense physical exercise may boost the bone density of certain fracture-prone bones in older women to the point where it equals that in men, according to a new study being presented this week at the 86th Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA).
Scientists from the fields of psychiatry, genetics and neurobiology will join in an information-exchange forum to address Alzheimer's disease research as it relates to genetic markers, medications (cognitive enhancers), minority populations, and clinical trial participation.
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