Trizivir, a new product that combines three anti-HIV medicines into one single tablet, has been approved by the Food and Drug Administration. This marks an important advance for dosing of combination drug regimens.
Patients with aspirin-induced asthma, who constitute from 10% to 20% of the approximately 15 million U.S. asthma sufferers, can be successfully desensitized if they must take the product. (Chest, 11-00)
Antiprotease augmentation therapy reduces lung infection in patients with Alpha 1-Antitrypsin deficiency, the most prevalent, potentially lethal hereditary disorder among the white adult population in the United States. (Chest, 11-00)
Knoll Pharmaceutical Company today launched a national weight management program that will provide people who have at least 30 pounds to lose with an opportunity to receive for free up to 12 months of the prescription weight-loss medication, MERIDIA(tm).
Medicare patients enrolled in managed-care plans were significantly less likely than those with traditional Medicare fee-for-service coverage to receive needed coronary angiography--a potentially lifesaving diagnostic procedure--following a heart attack, even though the procedure is a highly recommended practice (New England Journal of Medicine, 11-15-00).
Thanks to a brand new monitoring device under clinical investigation, Dr. Robert Bourge was able to connect one patientÃs Sunday shortness of breath to an almost-weekly Saturday night dinner date with his girlfriend.
How effectively the body uses the insulin it produces is directly related to risk of developing high blood pressure, reported researchers from Wake Forest University Baptist Medical Center today at the American Heart Association's annual conference.
American Heart Association's 73rd Scientific Sessions tips include: 1- Blood components indicate risk of rejecting a transplanted heart; 2- Women less likely to get "aggressive" treatment for vessel disease.
Laughter, along with an active sense of humor, may help protect you against a heart attack, according to a new study by cardiologists at the University of Maryland Medical Center in Baltimore, presented at the American Heart Association's Meeting 11-15-00 in New Orleans.
New study shows that Internet users should check online health information for web site authorship and potential conflicts of interest. (Journal of Bone and Joint Surgery, 11-00)
1. Pneumocystis carinii pneumonia (PCP) among patients with human immunodeficiency virus is clustered in specific zip codes; 2. Low birthweight and prematurity increase ozone's effect on asthmatic kids 4 to 9.
From a routine study of the life span of human skin cells, a University of Wisconsin-Madison research project gave rise to an astonishing accident: A line of skin cells that simply wouldn't die.
Many of the 48 million American smokers will try to quit during the Great American Smokeout on November 16. Here are 10 questions and answers that may help them. They are excerpted from a consumer brochure from the Surgeon General.
Patients in chronic pain are so dissatisfied with the efficacy of their prescription and over-the-counter pain control medications that 78 percent are willing to try new treatments and 43 percent would spend more on a treatment if they knew it would work, according to a U.S. survey.
After studies spanning more than a decade, scientists at the University of North Carolina at Chapel Hill have become the first to identify and purify hepatic stem cells, progenitor cells capable of regenerating liver and bile duct tissue. (National Academy of Sciences, 10-24-00)
There is considerable delay among parents in recognizing when children with advanced cancer have no realistic chance of cure, according to a Dana-Farber Cancer Institute and ChildrenÃs Hospital-Boston study published in the November 15 issue of JAMA.
Results from a multicenter clinical trial headed by researchers at the University of Alabama at Birmingham show that weight loss induced by Xenical (orlistat) can significantly reduce elevated blood pressure in overweight people.
Reporting at the American Heart Association's Scientific Sessions, a U.S. Department of Veterans Affairs researcher finds that people at risk for heart disease, were four times more likely than others to suffer a myocardial infarction soon after eating a big meal.
Surprise findings by researchers at the University of Alabama at Birmingham indicate that white stroke patients may have a higher incidence of atherosclerotic plaques than black stroke patients.
Researchers at the University of Maryland Medical Center in Baltimore now think they know why some of the people who take aspirin are not protected from heart attacks. Their study shows that in the unprotected patients, high cholesterol is hindering the effectiveness of the aspirin.
Researchers at the University of Maryland School of Medicine and the University of Southern California have discovered a genetic biomarker that may help doctors to better diagnose and treat cancer of the esophagus. (Journal of the National Cancer Institute, 11-15-00)
If mouse studies hold true for humans, a daily cup of yogurt or dose of antibiotics may become the first effective treatments for a common and sometimes fatal obesity-related liver disorder, Hopkins scientists report. (Gastroenterology, 11-00)
The diet drug combination fen-phen was removed from the market in 1997 because of its association with heart valve abnormalities. New research reveals cellular events, apparently triggered by the neurotransmitter serotonin, that may explain the disease mechanisms.
A new study reports that sildenafil citrate (Viagra), when combined with nitrates, can cause serious and prolonged decreases in blood flow through critically narrowed coronary arteries. (Circulation, 11-14-00)
A new Mayo Clinic study shows that the same underlying factors that cause people to seek out the behaviors of coffee or alcohol consumption or smoking may also make them less likely to develop ParkinsonÃs disease. The findings may point to a new, underlying risk factor that could be helpful in diagnosing and treating the disease. (Neurology, 11-14-00)
A new website, www.thebrainmatters.org, focuses on the personal and societal impacts of neurological diseases, providing profiles of seven people living with neurological diseases and resources for others seeking help and information. The website goes online, Friday, Nov. 10.
Parkinson's disease occurs in men two times more frequently than in women, according to a study in the November 14 issue of Neurology, the scientific journal of the American Academy of Neurology.
Drinking coffee may reduce the risk of ParkinsonÃs disease, according to a study published in the November 14 issue of Neurology, the scientific journal of the American Academy of Neurology.
Smoking and having low levels of "good" cholesterol can be extra risky in people who've already had a heart attack, said researchers from Wake Forest University Baptist Medical Center (WFUBMC) today at the American Heart Association's annual fall conference.
In cell biology studies, researchers report "strong evidence" that a molecule called ubiquilin controls levels of certain proteins that are central to the early development of Alzheimer's disease. (Journal of Cell Biology 11-00)
Diabetes is a known risk factor for mortality in patients with heart disease. Now a major new study by cardiac researchers at Intermountan Health Care's LDS Hospital has found heart disease patients who are not diabetic, but who have moderately elevated blood glucose levels, are also at significantly higher risk for death.
Sexual dysfunction in men with high blood pressure may be aided by the newest type of hypertension drug, reported a Wake Forest University Baptist Medical Center researcher at the American Heart Association's annual conference.
Reducing the number of medications taken by heart transplant patients can eliminate unpleasant and unhealthy side effects without increasing the risk of organ rejection, reported a Wake Forest University Baptist Medical Center researcher at the Southern Thoracic Surgical Association meeting.
A Johns Hopkins study of Korean Americans found that they have hypertension at rates much higher than other Americans or their counterparts in Korea.
An examination of two rare, very different and hereditary bone disorders has revealed clues about the common genetic switches controlling normal bone development, according to new research guided by a Johns Hopkins Children's Center endocrinologist.
AHRQ today announced funding for a major new research initiative, called the EXCEED (Excellence Centers to Eliminate Ethnic/Racial Disparities) Initiative, intended to improve knowledge of the factors underlying ethnic and racial inequities in health care.
People diagnosed with depression during the 1996 Depression Screening Day were more likely to follow treatment recommendations if they had health insurance. (American Journal of Psychiatry, 11-00)
A new study of twin and nontwin sibling pairs reinforces the theory that sexual orientation is significantly influenced by one's genes. The study is the only one known to have used a large national probability sample. (American Journal of Psychiatry, 11-00)
Researchers from Lawrence Livermore National Laboratory and the UC Davis Cancer Center have agreed to collaborate on an integrated cancer program. Some 10-12 projects are already underway.
A new international, multicenter study has confirmed that perfectionism is inherent in individuals with the eating disorder anorexia nervosa. (American Journal of Psychiatry, 11-00)
Americans who get hands-on help from others so that they can accomplish life's basic daily activities are not necessarily elderly nor do they all live in nursing homes, according to a new report by AHRQ. Roughly 79 percent live in places other than institutions, and almost half are under 65 years of age.
Metabolism of nicotine products produces a substance that is a direct precursor to the tobacco-specific lung carcinogen NNK. (Proceedings of the National Academy of Sciences, 10-24-00)
Ninety-seven percent of pregnant women fail to sleep through the night by the end of their pregnancy, according to a new study by researchers at Saint Joseph's University and Delaware County (Pa.) Memorial Hospital. (Journal of Obstetric, Gynecologic, and Neonatal Nursing, 10-00)
For 7-year-old Kyle Schepens - near death due to a virulent form of heart disease - a new and surprisingly hopeful treatment allowed him to celebrate his eighth birthday. (Heart and Lung Transplantation, 11-00)
The following tip sheet reports works-in-progress on the newest approaches to Alzheimer's disease, epilepsy, stem cell therapy and seasonality from Hopkins' neuroscientists attending this month's meeting in New Orleans, November 4 to 9.
Endostatin, a drug that seeks to reduce tumors by cutting off their blood supply, appears to be safe and well-tolerated, according to preliminary results on 19 people studied in Boston.
The upcoming winter holidays can be a painful reminder for those who have experienced the death of a loved one. A seminar on Monday, Nov. 13 in Rochester will address general issues of grief and identify specific issues of grief associated with the holidays.
University of Michigan scientists have identified genetic mutations that cause a serious medical condition called hereditary lymphedema-distichiasis or LD. (American Journal of Human Genetics, 12-00)
Mayo Clinic researchers have developed a new laboratory method for detecting recurring cancer of the bladder sooner and more accurately. (The Journal of Urology, 11-00)
A study concludes that a hip replacement device developed at Mayo Clinic is successful in conserving bone, making it an attractive choice for younger patients. (Journal of Bone and Joint Surgery, 9-00)
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